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The map label for this gene is tolC [C]

Identifier: 220931348

GI number: 220931348

Start: 546660

End: 548075

Strand: Direct

Name: tolC [C]

Synonym: Hore_05030

Alternate gene names: 220931348

Gene position: 546660-548075 (Clockwise)

Preceding gene: 220931347

Following gene: 220931349

Centisome position: 21.2

GC content: 38.7

Gene sequence:

>1416_bases
ATGTTTTTAAATAAAAGGTATATTTATTTTATTGTCATTTTAATGATGTTCAGTATTTTGGTACCTCTGGATAAAATATA
TGCTGAAGAAGTACTTACATTAACTGAAGTATTACAGGCAGGACTAAAGGAAAACCCGGATATTAAGAATACAAGACTGG
ATCTGGAAAATGCCAGGTTAGATTTGAGCATTTCCTGGCGTAACCTTTTACCTGAAGTAAACCTGCAGTCGGCCTATACC
AGGTTAGGGGAGCCACCACAGGTCCCGGGTTTTCAGTATCAACGTGTAGAGACCGGTATCCCGGGAGAATATCCCGACAG
TGATATTGTATACTTATATCCTGAAATGATTGAAGGTCCTCAGGATAATTATACAACTACTATCACCTTAAACCAGCCCC
TGTTTATGGGAGGGAGGTTGCTTCTGGGGATAGATCAGGCCAGAAAGGGTGTTGAACTGGCTAGAAGTGTCCTGGAGCAG
AAAAAGGAAGATACCCTGTACCAGCTCATTAACACCTATTATAATACCTTGCTGTTATCAGACCGGCTACAGGTTGAAGA
AGAGGGCCTGGACCTGATCAGGGAGCAAAAAGAGGTAATCAGGGCCGGTATTGAAGCCGGAACTATTTTAAAGACAGATC
TTCTCCAGGTGGAGATTGAAGAAAATAAAGCCTGGCAGCGTCTCCAGAAGGTAAAAAATCAGTATAAACTTGCCCTGAAA
CAATTATATGTAATGTCCGGGCTGGATAAAAGTGTTTTGAAGGAGCAAGAGGTTATACTTAAGAAGCCTCAGTTTAAACC
TGAAGTAAATATAAATGATCTGTCCAGTCTCATAAAATTAGCTAAAGAGAACAGGCCTGATTTAAAAATGTTATCCATCA
ATGAAGAGATGATAAAAAACAATATAACTATGGAAAAAAGAAGCAACTGGCCCAGTTTTATGGTCAGTGGAAACTATTCC
TGGCAGGGTGAGGAGTTAAAATTTGAAGACCCTGAATGGACAGTTACCATAAGTGGGAGTCTACCCCTGTTTCAGGGTGG
TAAATCGGGAAAGAGACTCAAAAAGATTAATAATGAATTTGATAAGATCAGAGAGAAAAAGCAATATGTTTCAGAAATGG
TTGAGGTTGAAGTAACAAATGTTTTTAACAAAATAAATGAACTTGAAGAAAATGTTGTTATTCAAGACCAGAATTTAAAC
AAGGCGCAGGAAAATTTAAGACTGGTTAATAGCAGGTATAAAGTAGGAATGGTCACCAATCTTGATGTTATGAATGCCCG
GTTGTTGTATCGGCAGAGTAAACTGGGACTCCTTCAGGCTGAGTTTAATTATAAACTGGCCATGTATGAACTGTTATATA
AAACCGGAAGACTTGGAGAGTTTGTTGAGGAGGTAGTTAACAATGAAACCAAATAA

Upstream 100 bases:

>100_bases
TCCAGCTTTATTATGTGATACTGAAGATGATATAGAGGAGCTGCTCGGTTTCAGTTTTGATTTTATTATGAAAGGATTGG
GGAAGGGGGATTAAAAAAGA

Downstream 100 bases:

>100_bases
ACCAGTAATAGTTACTTTAATGTTTTTAATGTTAGTTACGTTATTAAGCGGGCAGGTATTTGGTGAGACTCAAATACCGG
TTAGTGTTATTGAGCCCGGG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: Outer Membrane Protein; Type I Secretion Outer Membrane Protein lC Family; Outer Membrane Protein lC; LC Family Type I Secretion Outer Membrane Protein; Type I Secretion Outer Membrane Protein; Acriflavin Resistance Protein; Type I Secretion Outer Membrane Protein lC; Outer Membrane Channel Protein; Type I Secretion Outer Membrane Protein lc Family; Outer Membrane Macrolide Efflux Protein; Outer Membrane Efflux Protein Domain-Containing Protein; RND Efflux System Outer Membrane Lipoprotein; Outer Membrane Protein-Like; RND Efflux System Outer Membrane Lipoprotein NodT Family; RND Family Efflux Pump Outer Membrane Protein; Outer Membrane Protein-Like Protein; Periplasmic Type I Secretion System; ABC Export System Outer Membrane Protein; Type I Secretion Outer Membrane Protein RsaFb; Outer Membrane Efflux Family Protein; Outer Membrane Export Factor

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MFLNKRYIYFIVILMMFSILVPLDKIYAEEVLTLTEVLQAGLKENPDIKNTRLDLENARLDLSISWRNLLPEVNLQSAYT
RLGEPPQVPGFQYQRVETGIPGEYPDSDIVYLYPEMIEGPQDNYTTTITLNQPLFMGGRLLLGIDQARKGVELARSVLEQ
KKEDTLYQLINTYYNTLLLSDRLQVEEEGLDLIREQKEVIRAGIEAGTILKTDLLQVEIEENKAWQRLQKVKNQYKLALK
QLYVMSGLDKSVLKEQEVILKKPQFKPEVNINDLSSLIKLAKENRPDLKMLSINEEMIKNNITMEKRSNWPSFMVSGNYS
WQGEELKFEDPEWTVTISGSLPLFQGGKSGKRLKKINNEFDKIREKKQYVSEMVEVEVTNVFNKINELEENVVIQDQNLN
KAQENLRLVNSRYKVGMVTNLDVMNARLLYRQSKLGLLQAEFNYKLAMYELLYKTGRLGEFVEEVVNNETK

Sequences:

>Translated_471_residues
MFLNKRYIYFIVILMMFSILVPLDKIYAEEVLTLTEVLQAGLKENPDIKNTRLDLENARLDLSISWRNLLPEVNLQSAYT
RLGEPPQVPGFQYQRVETGIPGEYPDSDIVYLYPEMIEGPQDNYTTTITLNQPLFMGGRLLLGIDQARKGVELARSVLEQ
KKEDTLYQLINTYYNTLLLSDRLQVEEEGLDLIREQKEVIRAGIEAGTILKTDLLQVEIEENKAWQRLQKVKNQYKLALK
QLYVMSGLDKSVLKEQEVILKKPQFKPEVNINDLSSLIKLAKENRPDLKMLSINEEMIKNNITMEKRSNWPSFMVSGNYS
WQGEELKFEDPEWTVTISGSLPLFQGGKSGKRLKKINNEFDKIREKKQYVSEMVEVEVTNVFNKINELEENVVIQDQNLN
KAQENLRLVNSRYKVGMVTNLDVMNARLLYRQSKLGLLQAEFNYKLAMYELLYKTGRLGEFVEEVVNNETK
>Mature_471_residues
MFLNKRYIYFIVILMMFSILVPLDKIYAEEVLTLTEVLQAGLKENPDIKNTRLDLENARLDLSISWRNLLPEVNLQSAYT
RLGEPPQVPGFQYQRVETGIPGEYPDSDIVYLYPEMIEGPQDNYTTTITLNQPLFMGGRLLLGIDQARKGVELARSVLEQ
KKEDTLYQLINTYYNTLLLSDRLQVEEEGLDLIREQKEVIRAGIEAGTILKTDLLQVEIEENKAWQRLQKVKNQYKLALK
QLYVMSGLDKSVLKEQEVILKKPQFKPEVNINDLSSLIKLAKENRPDLKMLSINEEMIKNNITMEKRSNWPSFMVSGNYS
WQGEELKFEDPEWTVTISGSLPLFQGGKSGKRLKKINNEFDKIREKKQYVSEMVEVEVTNVFNKINELEENVVIQDQNLN
KAQENLRLVNSRYKVGMVTNLDVMNARLLYRQSKLGLLQAEFNYKLAMYELLYKTGRLGEFVEEVVNNETK

Specific function: Required For Proper Expression Of Outer Membrane Protein Genes Such As Ompf, Nmpc, Protein 2, Hemolysin, Colicin V, Or Colicin E1. May Be Specialized For Signal Sequence Independent, Extracellular Secretion In Gram-Negative Bacteria. [C]

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Outer Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 54661; Mature: 54661

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLNKRYIYFIVILMMFSILVPLDKIYAEEVLTLTEVLQAGLKENPDIKNTRLDLENARL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEE
DLSISWRNLLPEVNLQSAYTRLGEPPQVPGFQYQRVETGIPGEYPDSDIVYLYPEMIEGP
EEEEEHHHCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEHHHHCCC
QDNYTTTITLNQPLFMGGRLLLGIDQARKGVELARSVLEQKKEDTLYQLINTYYNTLLLS
CCCCEEEEEECCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLQVEEEGLDLIREQKEVIRAGIEAGTILKTDLLQVEIEENKAWQRLQKVKNQYKLALK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHH
QLYVMSGLDKSVLKEQEVILKKPQFKPEVNINDLSSLIKLAKENRPDLKMLSINEEMIKN
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHC
NITMEKRSNWPSFMVSGNYSWQGEELKFEDPEWTVTISGSLPLFQGGKSGKRLKKINNEF
CCCCHHCCCCCCEEEECCCCCCCCCCEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
DKIREKKQYVSEMVEVEVTNVFNKINELEENVVIQDQNLNKAQENLRLVNSRYKVGMVTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHCCEEEEEEEC
LDVMNARLLYRQSKLGLLQAEFNYKLAMYELLYKTGRLGEFVEEVVNNETK
CHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MFLNKRYIYFIVILMMFSILVPLDKIYAEEVLTLTEVLQAGLKENPDIKNTRLDLENARL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEE
DLSISWRNLLPEVNLQSAYTRLGEPPQVPGFQYQRVETGIPGEYPDSDIVYLYPEMIEGP
EEEEEHHHCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCEEEEEHHHHCCC
QDNYTTTITLNQPLFMGGRLLLGIDQARKGVELARSVLEQKKEDTLYQLINTYYNTLLLS
CCCCEEEEEECCCHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DRLQVEEEGLDLIREQKEVIRAGIEAGTILKTDLLQVEIEENKAWQRLQKVKNQYKLALK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHH
QLYVMSGLDKSVLKEQEVILKKPQFKPEVNINDLSSLIKLAKENRPDLKMLSINEEMIKN
HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCHHHHHC
NITMEKRSNWPSFMVSGNYSWQGEELKFEDPEWTVTISGSLPLFQGGKSGKRLKKINNEF
CCCCHHCCCCCCEEEECCCCCCCCCCEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHHH
DKIREKKQYVSEMVEVEVTNVFNKINELEENVVIQDQNLNKAQENLRLVNSRYKVGMVTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHHCCEEEEEEEC
LDVMNARLLYRQSKLGLLQAEFNYKLAMYELLYKTGRLGEFVEEVVNNETK
CHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA