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The map label for this gene is fadR [H]

Identifier: 220931347

GI number: 220931347

Start: 546069

End: 546653

Strand: Direct

Name: fadR [H]

Synonym: Hore_05020

Alternate gene names: 220931347

Gene position: 546069-546653 (Clockwise)

Preceding gene: 220931342

Following gene: 220931348

Centisome position: 21.18

GC content: 37.78

Gene sequence:

>585_bases
ATGAAAGGGCAGGAAGCATTAACTACCAGAGATGAAATATTGAAGGCTGCCAGGAATTTATTTGCCGAGAGGGGGTTCCA
TGAGGCTTCCATGTCCAGTATTGCTAAAGAAGCCGGAGTAGGCAAAGGGACCCTGTACTGGTATTTTGACAGTAAACAGG
AACTATTTAAGGAATTAATAAAAACCGGTGGTAAAATTATTGAAGACAAGATACATAAATGGGTAAAAGAGGAGACTTCA
CCTGAAGAATTTATAAAAATGTTTATTGAAACAGGACTGAAACATCTTTCCAATAATAAAAGAATAATCAGGGCATTATT
CTCCAGTGATGAACTGGGAAGAGAGTTTAAGCGAGAATTATTTGAAACCAGGTACAGAATTATTAACAGTCTGGAAATGG
TGATACAGCAGGGGATAAATGAAGGGAAATTTAGAGAGGTTTCAACCAGACACGCTGCTGCCGCTATTATAGGTATAATA
AATGGTATGACTCCAGCTTTATTATGTGATACTGAAGATGATATAGAGGAGCTGCTCGGTTTCAGTTTTGATTTTATTAT
GAAAGGATTGGGGAAGGGGGATTAA

Upstream 100 bases:

>100_bases
CTGTTAAAAACATTAATTTTTTTGACATAAATTAAAAATAGTGTTAAAATAATAATTGACTGACCGGTAGGTCGAGAAGA
ATATACCAGGAGGAGATAGC

Downstream 100 bases:

>100_bases
AAAAGAATGTTTTTAAATAAAAGGTATATTTATTTTATTGTCATTTTAATGATGTTCAGTATTTTGGTACCTCTGGATAA
AATATATGCTGAAGAAGTAC

Product: TetR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MKGQEALTTRDEILKAARNLFAERGFHEASMSSIAKEAGVGKGTLYWYFDSKQELFKELIKTGGKIIEDKIHKWVKEETS
PEEFIKMFIETGLKHLSNNKRIIRALFSSDELGREFKRELFETRYRIINSLEMVIQQGINEGKFREVSTRHAAAAIIGII
NGMTPALLCDTEDDIEELLGFSFDFIMKGLGKGD

Sequences:

>Translated_194_residues
MKGQEALTTRDEILKAARNLFAERGFHEASMSSIAKEAGVGKGTLYWYFDSKQELFKELIKTGGKIIEDKIHKWVKEETS
PEEFIKMFIETGLKHLSNNKRIIRALFSSDELGREFKRELFETRYRIINSLEMVIQQGINEGKFREVSTRHAAAAIIGII
NGMTPALLCDTEDDIEELLGFSFDFIMKGLGKGD
>Mature_194_residues
MKGQEALTTRDEILKAARNLFAERGFHEASMSSIAKEAGVGKGTLYWYFDSKQELFKELIKTGGKIIEDKIHKWVKEETS
PEEFIKMFIETGLKHLSNNKRIIRALFSSDELGREFKRELFETRYRIINSLEMVIQQGINEGKFREVSTRHAAAAIIGII
NGMTPALLCDTEDDIEELLGFSFDFIMKGLGKGD

Specific function: Transcriptional regulator in fatty acid degradation. Represses transcription of genes required for fatty acid transport and beta-oxidation, including acdA, fadA, fadB, fadE, fadF, fadG, fadH, fadM, fadN, lcfA and lcfB. Binding of FadR to DNA is specifical

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH tetR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR015893
- InterPro:   IPR011075
- InterPro:   IPR001647
- InterPro:   IPR013570 [H]

Pfam domain/function: PF08359 TetR_C_4; PF00440 TetR_N [H]

EC number: NA

Molecular weight: Translated: 22101; Mature: 22101

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS01081 HTH_TETR_1 ; PS50977 HTH_TETR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGQEALTTRDEILKAARNLFAERGFHEASMSSIAKEAGVGKGTLYWYFDSKQELFKELI
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHH
KTGGKIIEDKIHKWVKEETSPEEFIKMFIETGLKHLSNNKRIIRALFSSDELGREFKREL
HHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHH
FETRYRIINSLEMVIQQGINEGKFREVSTRHAAAAIIGIINGMTPALLCDTEDDIEELLG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHC
FSFDFIMKGLGKGD
CCHHHHHHHCCCCC
>Mature Secondary Structure
MKGQEALTTRDEILKAARNLFAERGFHEASMSSIAKEAGVGKGTLYWYFDSKQELFKELI
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHH
KTGGKIIEDKIHKWVKEETSPEEFIKMFIETGLKHLSNNKRIIRALFSSDELGREFKREL
HHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHH
FETRYRIINSLEMVIQQGINEGKFREVSTRHAAAAIIGIINGMTPALLCDTEDDIEELLG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHC
FSFDFIMKGLGKGD
CCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]