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The map label for this gene is bepF [H]

Identifier: 220931349

GI number: 220931349

Start: 548062

End: 549591

Strand: Direct

Name: bepF [H]

Synonym: Hore_05040

Alternate gene names: 220931349

Gene position: 548062-549591 (Clockwise)

Preceding gene: 220931348

Following gene: 220931350

Centisome position: 21.26

GC content: 42.81

Gene sequence:

>1530_bases
ATGAAACCAAATAAACCAGTAATAGTTACTTTAATGTTTTTAATGTTAGTTACGTTATTAAGCGGGCAGGTATTTGGTGA
GACTCAAATACCGGTTAGTGTTATTGAGCCCGGGGTTAAAAGTATCAGGGTTGAGGAATCTGTTACCGGGGTTATAAAAC
CCTATCAGGTGGTTAATTTATCAACAAAAACAGGCGGAATAGTTGATGAGATTCTGGTTGAGGTTGGTCAAAGGGTTGAA
GCAGGTGAACCCCTGTTAAAGCTTGAACAGGAAGAATTAAAGGCCCAGGTAAAGCAGGCCAGAGCTCAACTTGCCATGGC
AAGGGCTTCTTTCAAAAAAATAAAGGATGGAGCCAGTCCAGAAGATGTTGAAAAAGTTCGTGGTGCCTATAACCAGGCCC
TTGCTTCATATAATGGAGCCAGAAAAGCCTTGAATATAATAAAAGATATGTATGAGGATAAAACAAGTCAGGAACAGCAG
CTTACAGCAGCCAGGACAAAGCTGGACACTGCCTCTAAAAAGCTGGAACTGGCCCGGGAGCAACTGAAGCAGACTGAAGT
AAGTTATGAACAGGCGGAAAAGAGTTATAAGAGGATGGAGTACCTCTATGAAGAGGGAGTAATTACTGAAAGTGAATTTG
ATAAAGTTAAAACCCAGTATGAAAATGCAAAATCTGCTCTCAAGTCGGCTGAACTGGGACTGGAACAGGCTAAGGTCAAT
TATGAGGGGGCCCTTAAAGGGTATAATCTGGTTAAAGAAATCTATGAAAACCCCCGGTCCCTGGAACAGCAGCTTTTAAA
TGCTGAAACCCAGTATGAAGTGGCCAAAGCCAACCTCCAGATTGCTAAAGCCAACCTGGACCAGGTTCTAATGGGGGCTG
AAGAGGAGGATTTACAGTCAGCCCGGGCCCAGGTGGAACAGGCTGAAGTTGCCCTGGAATTGGCCAACATTAGACTCAGG
GATAGTGTCTTAGAAAGCCCGTTTCCGGGACTTATTGCTGCTGTTAATATTAATGAAGGTGAGATGGCCCCTCCAGGAAA
TCCTGTTATCAAGGTTGTTAACCTTGATAAAGTGTATGCTGAAATTGAGGTATCAGCCAGTACAGTAACCAGTTTAGAGA
CAGGTGATCTAGTAAGAGTAGAGATCCTTCCACTGGCTAATATGTCTATGACAGGTAAAATAGAGACAATTGCTCCTGAT
GTAGATCCGCGGAGCAGAGCCTATCCTGTTAAGGTAGTTATCCCCAATTCGAAAAATATGATTAAAGGGGGAATGTATTG
TCGGGTTTACCTTACGTTAAAAGAGTCAAATCGTGGGGTAGTTGTCCCGGTAGATTCTGTTCTTGACCTGGAAGAAAAAC
CCTATATATTTGTAGTTAATAACGGTAAGGCTGAAAAGAGATTTATTGAGACGGGCTTAATTAACGATACAGAAGTTCAG
GTCATTGATGGTTTGAATCCTGATGAAAGAGTTGTAGTCAAGGGCCAGTATAAACTTACCGATGGGGCTCCGGTTAAGGT
GGTGAACTAA

Upstream 100 bases:

>100_bases
CTGGGACTCCTTCAGGCTGAGTTTAATTATAAACTGGCCATGTATGAACTGTTATATAAAACCGGAAGACTTGGAGAGTT
TGTTGAGGAGGTAGTTAACA

Downstream 100 bases:

>100_bases
AATGAAATTACCTGATCTGGCAATAAAAAGACCGGTTACAACAACAATGATAGTTTTACTTGCAGTCCTGCTGGGTTTTA
TCTCCCTGACAAGGGTAAAC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 509; Mature: 509

Protein sequence:

>509_residues
MKPNKPVIVTLMFLMLVTLLSGQVFGETQIPVSVIEPGVKSIRVEESVTGVIKPYQVVNLSTKTGGIVDEILVEVGQRVE
AGEPLLKLEQEELKAQVKQARAQLAMARASFKKIKDGASPEDVEKVRGAYNQALASYNGARKALNIIKDMYEDKTSQEQQ
LTAARTKLDTASKKLELAREQLKQTEVSYEQAEKSYKRMEYLYEEGVITESEFDKVKTQYENAKSALKSAELGLEQAKVN
YEGALKGYNLVKEIYENPRSLEQQLLNAETQYEVAKANLQIAKANLDQVLMGAEEEDLQSARAQVEQAEVALELANIRLR
DSVLESPFPGLIAAVNINEGEMAPPGNPVIKVVNLDKVYAEIEVSASTVTSLETGDLVRVEILPLANMSMTGKIETIAPD
VDPRSRAYPVKVVIPNSKNMIKGGMYCRVYLTLKESNRGVVVPVDSVLDLEEKPYIFVVNNGKAEKRFIETGLINDTEVQ
VIDGLNPDERVVVKGQYKLTDGAPVKVVN

Sequences:

>Translated_509_residues
MKPNKPVIVTLMFLMLVTLLSGQVFGETQIPVSVIEPGVKSIRVEESVTGVIKPYQVVNLSTKTGGIVDEILVEVGQRVE
AGEPLLKLEQEELKAQVKQARAQLAMARASFKKIKDGASPEDVEKVRGAYNQALASYNGARKALNIIKDMYEDKTSQEQQ
LTAARTKLDTASKKLELAREQLKQTEVSYEQAEKSYKRMEYLYEEGVITESEFDKVKTQYENAKSALKSAELGLEQAKVN
YEGALKGYNLVKEIYENPRSLEQQLLNAETQYEVAKANLQIAKANLDQVLMGAEEEDLQSARAQVEQAEVALELANIRLR
DSVLESPFPGLIAAVNINEGEMAPPGNPVIKVVNLDKVYAEIEVSASTVTSLETGDLVRVEILPLANMSMTGKIETIAPD
VDPRSRAYPVKVVIPNSKNMIKGGMYCRVYLTLKESNRGVVVPVDSVLDLEEKPYIFVVNNGKAEKRFIETGLINDTEVQ
VIDGLNPDERVVVKGQYKLTDGAPVKVVN
>Mature_509_residues
MKPNKPVIVTLMFLMLVTLLSGQVFGETQIPVSVIEPGVKSIRVEESVTGVIKPYQVVNLSTKTGGIVDEILVEVGQRVE
AGEPLLKLEQEELKAQVKQARAQLAMARASFKKIKDGASPEDVEKVRGAYNQALASYNGARKALNIIKDMYEDKTSQEQQ
LTAARTKLDTASKKLELAREQLKQTEVSYEQAEKSYKRMEYLYEEGVITESEFDKVKTQYENAKSALKSAELGLEQAKVN
YEGALKGYNLVKEIYENPRSLEQQLLNAETQYEVAKANLQIAKANLDQVLMGAEEEDLQSARAQVEQAEVALELANIRLR
DSVLESPFPGLIAAVNINEGEMAPPGNPVIKVVNLDKVYAEIEVSASTVTSLETGDLVRVEILPLANMSMTGKIETIAPD
VDPRSRAYPVKVVIPNSKNMIKGGMYCRVYLTLKESNRGVVVPVDSVLDLEEKPYIFVVNNGKAEKRFIETGLINDTEVQ
VIDGLNPDERVVVKGQYKLTDGAPVKVVN

Specific function: May contribute to resistance to some drugs, such as deoxycholate, sodium dodecyl sulfate and nalidixic acid, in the absence of BepD and BepE [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 56236; Mature: 56236

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNKPVIVTLMFLMLVTLLSGQVFGETQIPVSVIEPGVKSIRVEESVTGVIKPYQVVNL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHEEEHHHHHCCCCCEEEEEE
STKTGGIVDEILVEVGQRVEAGEPLLKLEQEELKAQVKQARAQLAMARASFKKIKDGASP
CCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EDVEKVRGAYNQALASYNGARKALNIIKDMYEDKTSQEQQLTAARTKLDTASKKLELARE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QLKQTEVSYEQAEKSYKRMEYLYEEGVITESEFDKVKTQYENAKSALKSAELGLEQAKVN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
YEGALKGYNLVKEIYENPRSLEQQLLNAETQYEVAKANLQIAKANLDQVLMGAEEEDLQS
CCCCHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHCCEEEEECCHHHHHHCCCHHHHHH
ARAQVEQAEVALELANIRLRDSVLESPFPGLIAAVNINEGEMAPPGNPVIKVVNLDKVYA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCEEEE
EIEVSASTVTSLETGDLVRVEILPLANMSMTGKIETIAPDVDPRSRAYPVKVVIPNSKNM
EEEECHHHEEECCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCC
IKGGMYCRVYLTLKESNRGVVVPVDSVLDLEEKPYIFVVNNGKAEKRFIETGLINDTEVQ
CCCCEEEEEEEEEEECCCEEEEECHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCCCCEE
VIDGLNPDERVVVKGQYKLTDGAPVKVVN
EEECCCCCCEEEEEEEEEECCCCCEEEEC
>Mature Secondary Structure
MKPNKPVIVTLMFLMLVTLLSGQVFGETQIPVSVIEPGVKSIRVEESVTGVIKPYQVVNL
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHEEEHHHHHCCCCCEEEEEE
STKTGGIVDEILVEVGQRVEAGEPLLKLEQEELKAQVKQARAQLAMARASFKKIKDGASP
CCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EDVEKVRGAYNQALASYNGARKALNIIKDMYEDKTSQEQQLTAARTKLDTASKKLELARE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QLKQTEVSYEQAEKSYKRMEYLYEEGVITESEFDKVKTQYENAKSALKSAELGLEQAKVN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
YEGALKGYNLVKEIYENPRSLEQQLLNAETQYEVAKANLQIAKANLDQVLMGAEEEDLQS
CCCCHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHCCEEEEECCHHHHHHCCCHHHHHH
ARAQVEQAEVALELANIRLRDSVLESPFPGLIAAVNINEGEMAPPGNPVIKVVNLDKVYA
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEECCEEEE
EIEVSASTVTSLETGDLVRVEILPLANMSMTGKIETIAPDVDPRSRAYPVKVVIPNSKNM
EEEECHHHEEECCCCCEEEEEEEEECCCCCCCEEEEECCCCCCCCCCEEEEEEECCCCCC
IKGGMYCRVYLTLKESNRGVVVPVDSVLDLEEKPYIFVVNNGKAEKRFIETGLINDTEVQ
CCCCEEEEEEEEEEECCCEEEEECHHHHCCCCCCEEEEEECCCHHHHHHHHCCCCCCCEE
VIDGLNPDERVVVKGQYKLTDGAPVKVVN
EEECCCCCCEEEEEEEEEECCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12271122 [H]