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The map label for this gene is radA [H]

Identifier: 220930936

GI number: 220930936

Start: 106731

End: 108086

Strand: Direct

Name: radA [H]

Synonym: Hore_00880

Alternate gene names: 220930936

Gene position: 106731-108086 (Clockwise)

Preceding gene: 220930935

Following gene: 220930937

Centisome position: 4.14

GC content: 42.85

Gene sequence:

>1356_bases
ATGCCCAGACCTAAAACCTATTATATCTGCAGTGAATGTGGTTATAAATCTGCTAAATGGATGGGACGTTGTCTAAACTG
TGGTGCCTGGAATACTTTTCAGGAACTGGATGAAGAAGCCATTGAGGAAAAGGTGGATATCAAGGTTACCCCTAGTTCAA
TAACTGATATAAAAGCCGGGGCCTGTCCCCGGCTTTCTTCCGGTATTGGGGAGTTTGACAGGGTGCTTGGTGGAGGTGTT
GTGCCCGGTTCTTTAATTCTACTTGGAGGTGCCCCTGGAATAGGTAAATCGACCCTGGTTCTTCAAATGGCCAGGCACTT
CAGCGAAAAATATGGAAAAGTTTTATATGTCAGTGGTGAAGAATCAGCTTCCCAGTTAAAAATGAGGGCCGGGAGGCTCG
GGGCTATAAATGAGGATTTATATGTTCTTTCTGAAACTAATTTTCAACAAATTTATGGTGTTATACAAAATGAAAAATAT
GAATTAATAATAATAGATTCTATACAAACAATATTTGACCCCCGGATTGAATCTACCCCCGGTAGTATAAGCCAGGTTAA
GGAAGTTACTAATAGGTTACTTATTCAGGCCAAGAAACTGGAAGTTCCCATCGTTTTAATAGGACATGTTACCAAGGAAG
GACATCTGGCCGGTCCCCGGGTCCTGGAACATTTGGTTGATACAGTTCTTCAGTTTGAAGGGGACAGGAATTACATCTAT
CGAATTCTCAGGGCAGTAAAAAATCGTTTTGGCTCTACAAATGAGATAGGTGTCTTTGAAATGATGGGAAGTGGTATGAG
AGAAGTGGTTAATCCCTCGGAAATTTTCCTTAAAGGGAGGGCCCAGGGGGTATCGGGTTCTGTGATAGTTCCGGTTGTCG
AGGGGAGTAGACCCCTTCTTGTTGAGGTTCAGGCCCTGGTAACCTACTCGAGTTTTGGGACCCCCCAGCGGTTAACAACC
GGTGTTGACCGGAAGAGGGTTTCTATTTTACTGGCTGTCCTGGAGAAAAAGGCTGGTATTAATTTTCATAATCAGGATGT
TAATATTAATATAACAGGGGGCTTAAAAGTAGAAGAGCCGGCCCTGGATCTCGGTATAATAACAGCTATTTTATCAAGTT
GTAAAGACCAGGAGGTAGCTCCGGACCTGGCTGTGATTGGAGAAGTAGGACTGGCCGGGGAGATACGGGCTGTCAGTCAG
ATAGAGAGGCGTTTAAGTGAATTAAAAAAGATGGGCTTTAAGGAAGTTGTTATTCCTGGAGGCAATATATCTGGTCTGGA
CTTTGACCCGGATATTAATATAGTTGAAGTTAAAAATGTTAATGATCTCATGAAGATATTGTTTAACAGGAGGTGA

Upstream 100 bases:

>100_bases
TGGGAAAGTAGTCGTGGGCAAATGACCCGGTTTATTGTTGTAAAATCATGACAAAAATGTTATAATGAAAATATCACTAT
ATTTCGGGAGTTAAAGAATT

Downstream 100 bases:

>100_bases
TGTAATGGATGGAAAAAAGGTGAGCTGGGGTGAAGTACTAAAAATTCTGGCTCCGGGAACCCTGCTCAGGGAAGGGCTTG
AAAATGTGTTACGTGCTAAA

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms homolog [H]

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MPRPKTYYICSECGYKSAKWMGRCLNCGAWNTFQELDEEAIEEKVDIKVTPSSITDIKAGACPRLSSGIGEFDRVLGGGV
VPGSLILLGGAPGIGKSTLVLQMARHFSEKYGKVLYVSGEESASQLKMRAGRLGAINEDLYVLSETNFQQIYGVIQNEKY
ELIIIDSIQTIFDPRIESTPGSISQVKEVTNRLLIQAKKLEVPIVLIGHVTKEGHLAGPRVLEHLVDTVLQFEGDRNYIY
RILRAVKNRFGSTNEIGVFEMMGSGMREVVNPSEIFLKGRAQGVSGSVIVPVVEGSRPLLVEVQALVTYSSFGTPQRLTT
GVDRKRVSILLAVLEKKAGINFHNQDVNINITGGLKVEEPALDLGIITAILSSCKDQEVAPDLAVIGEVGLAGEIRAVSQ
IERRLSELKKMGFKEVVIPGGNISGLDFDPDINIVEVKNVNDLMKILFNRR

Sequences:

>Translated_451_residues
MPRPKTYYICSECGYKSAKWMGRCLNCGAWNTFQELDEEAIEEKVDIKVTPSSITDIKAGACPRLSSGIGEFDRVLGGGV
VPGSLILLGGAPGIGKSTLVLQMARHFSEKYGKVLYVSGEESASQLKMRAGRLGAINEDLYVLSETNFQQIYGVIQNEKY
ELIIIDSIQTIFDPRIESTPGSISQVKEVTNRLLIQAKKLEVPIVLIGHVTKEGHLAGPRVLEHLVDTVLQFEGDRNYIY
RILRAVKNRFGSTNEIGVFEMMGSGMREVVNPSEIFLKGRAQGVSGSVIVPVVEGSRPLLVEVQALVTYSSFGTPQRLTT
GVDRKRVSILLAVLEKKAGINFHNQDVNINITGGLKVEEPALDLGIITAILSSCKDQEVAPDLAVIGEVGLAGEIRAVSQ
IERRLSELKKMGFKEVVIPGGNISGLDFDPDINIVEVKNVNDLMKILFNRR
>Mature_450_residues
PRPKTYYICSECGYKSAKWMGRCLNCGAWNTFQELDEEAIEEKVDIKVTPSSITDIKAGACPRLSSGIGEFDRVLGGGVV
PGSLILLGGAPGIGKSTLVLQMARHFSEKYGKVLYVSGEESASQLKMRAGRLGAINEDLYVLSETNFQQIYGVIQNEKYE
LIIIDSIQTIFDPRIESTPGSISQVKEVTNRLLIQAKKLEVPIVLIGHVTKEGHLAGPRVLEHLVDTVLQFEGDRNYIYR
ILRAVKNRFGSTNEIGVFEMMGSGMREVVNPSEIFLKGRAQGVSGSVIVPVVEGSRPLLVEVQALVTYSSFGTPQRLTTG
VDRKRVSILLAVLEKKAGINFHNQDVNINITGGLKVEEPALDLGIITAILSSCKDQEVAPDLAVIGEVGLAGEIRAVSQI
ERRLSELKKMGFKEVVIPGGNISGLDFDPDINIVEVKNVNDLMKILFNRR

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=456, Percent_Identity=44.5175438596491, Blast_Score=388, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 49372; Mature: 49241

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRPKTYYICSECGYKSAKWMGRCLNCGAWNTFQELDEEAIEEKVDIKVTPSSITDIKAG
CCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCC
ACPRLSSGIGEFDRVLGGGVVPGSLILLGGAPGIGKSTLVLQMARHFSEKYGKVLYVSGE
CCCCHHHCHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECC
ESASQLKMRAGRLGAINEDLYVLSETNFQQIYGVIQNEKYELIIIDSIQTIFDPRIESTP
CHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCCEEEEEEECHHHHHCCCCCCCC
GSISQVKEVTNRLLIQAKKLEVPIVLIGHVTKEGHLAGPRVLEHLVDTVLQFEGDRNYIY
CHHHHHHHHHHHHHEEHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHH
RILRAVKNRFGSTNEIGVFEMMGSGMREVVNPSEIFLKGRAQGVSGSVIVPVVEGSRPLL
HHHHHHHHHCCCCCCCCHHHHHCCCHHHHCCHHHEEEEECCCCCCCCEEEEEECCCCCEE
VEVQALVTYSSFGTPQRLTTGVDRKRVSILLAVLEKKAGINFHNQDVNINITGGLKVEEP
EEEEEHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEECCEEEEEEECCCEECCC
ALDLGIITAILSSCKDQEVAPDLAVIGEVGLAGEIRAVSQIERRLSELKKMGFKEVVIPG
CHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECC
GNISGLDFDPDINIVEVKNVNDLMKILFNRR
CCCCCCCCCCCCCEEEECCHHHHHHHHHCCC
>Mature Secondary Structure 
PRPKTYYICSECGYKSAKWMGRCLNCGAWNTFQELDEEAIEEKVDIKVTPSSITDIKAG
CCCCEEEEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCC
ACPRLSSGIGEFDRVLGGGVVPGSLILLGGAPGIGKSTLVLQMARHFSEKYGKVLYVSGE
CCCCHHHCHHHHHHHHCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEECC
ESASQLKMRAGRLGAINEDLYVLSETNFQQIYGVIQNEKYELIIIDSIQTIFDPRIESTP
CHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCCEEEEEEECHHHHHCCCCCCCC
GSISQVKEVTNRLLIQAKKLEVPIVLIGHVTKEGHLAGPRVLEHLVDTVLQFEGDRNYIY
CHHHHHHHHHHHHHEEHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHH
RILRAVKNRFGSTNEIGVFEMMGSGMREVVNPSEIFLKGRAQGVSGSVIVPVVEGSRPLL
HHHHHHHHHCCCCCCCCHHHHHCCCHHHHCCHHHEEEEECCCCCCCCEEEEEECCCCCEE
VEVQALVTYSSFGTPQRLTTGVDRKRVSILLAVLEKKAGINFHNQDVNINITGGLKVEEP
EEEEEHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHCCCCEECCEEEEEEECCCEECCC
ALDLGIITAILSSCKDQEVAPDLAVIGEVGLAGEIRAVSQIERRLSELKKMGFKEVVIPG
CHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECC
GNISGLDFDPDINIVEVKNVNDLMKILFNRR
CCCCCCCCCCCCCEEEECCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 8016066 [H]