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The map label for this gene is clpC [H]

Identifier: 220930935

GI number: 220930935

Start: 104235

End: 106655

Strand: Direct

Name: clpC [H]

Synonym: Hore_00870

Alternate gene names: 220930935

Gene position: 104235-106655 (Clockwise)

Preceding gene: 220930934

Following gene: 220930936

Centisome position: 4.04

GC content: 42.63

Gene sequence:

>2421_bases
ATGTTCGGGAGATTTACTGAAAGAGCAAGAAAAGTTTTAAGTCTGGCCGAAAAAGAAGCTGTTGGCTTTAAACATAACTA
TGTAGGCACAGAGCATATTTTGCTGGGTCTGGTTAAAGAAGGGCAGGGAGTTGCTGCAAAGGCTCTAAAAGATGTTGGTA
TCTCTGAAGAAAAAGTTAAGGAGCAGATAACCAAGTTGATCGGTGAGGGAAATCAGGAGGTGAGTGGACCTATCAGTCTT
ACCCCCCGGAGTAAAAAGGTCCTCAACCTGGCTCTGGATGAGGCCAGGCGTCTCGGTCATAACTATATTGGAACCGAGCA
TATCTTGCTGGGATTAATTAGAGAAGGAGAAGGTGTAGCTGTTAGAATCCTGGCAAATCTTAATAATGGTGACCTCCAAA
ATATCAGGGAACAGGTAATTGAGTTACTTGGTGGTAAAGGGAATACCCGCCATCAGGATGGAACCAGGAGGAGTGAAACC
CCTAATTTAGATGAATATAGCAGGGATTTGACCAAACTGGCTGATCAGGTTAAGCTTGATCCGGTCATCGGACGCGAAAA
GGAAATAGAAAGGGTCATTCAGGTTTTAAGCAGGAGAACCAAGAATAACCCGGTTTTAATCGGAGAGCCCGGGGTTGGTA
AAACCGCCATTGTGGAAGGTTTGGCTCAGCGTATTGTCGATGAAAGTGTTCCTGATGTATTACTGAATAAAAGGGTAGTT
GCTTTAGATTTAAGTTCAATTGTAGCCGGTTCTAAATACAGGGGTGAATTTGAAAAGAGACTTAAGGCTGTTATGAATGA
TATAGTGAAAAGTGGTAATATTATTCTATTTATTGATGAGCTTCACACTCTGGTGGGAGCAGGTGCTGCTGAAGGTGCTA
TTGATGCGGCCAATATTCTCAAACCGGCTCTTGCCCGTGGTGAGCTTCAGGCCATCGGAGCCACTACCCTCGATGAGTAT
CGAAAATATATTGAAAAAGACCCGGCCCTGGAAAGGAGATTCCAGTCCATTCTGGTAGAGGAGCCGACTCCGGAAGAGAC
TATAGAGATTTTGAAGGGGCTACGGGACCCCTATGAAGCCCATCATAAAGTCAAGATAAGTGATGAAGCTATTAAAGCGG
CTGTAAACCTTTCACACCGTTATATTACTGACCGGTTTTTACCCGATAAAGCCATTGATCTTATCGATGAAGCTGCCTCC
AGGGTAAGACTGGGTAGTGATACCAGACCACCTGAATTAAAAGATTTGAATAAAAAGCTGGAAGAGGTAAAAAAAGAAAA
GGAAGCCGCGGTTAAGAATCAGGAATTTGAAAAAGCTGCTGAATTAAGGGATAAAGAAAAAGAACTAGAGAAAGAGTTTG
AAAACATTCAGGAGAAATGGGAAAAAGAAAAAGAAAAGAGTGAAAGTACTGTAACCACTGAGGAAATAGCAGAGATAGTT
TCAAGCTGGACCGGAATACCTGTAACCAAGCTTGAGCAAGCAGAAACTGCCAAACTACTCCATCTAGAAGAAGAGCTGCA
CAAACGGGTAGTTGGCCAGGACGAGGCCATTCAGGCTGTTTCCCAGGCGGTGAGAAGGGCCCGGGCTGGTTTAAAGGATC
CGAAGAGACCGATTGGCTCATTTATTTTTCTTGGTCCTACTGGAGTTGGGAAAACTGAGCTGGCCAGGGCTCTGGCTGAA
GCTATGTTTAATGATGAAGAGACTATGGTAAGAATAGATATGTCCGAATATATGGAAAAACATGCTGTATCAAGACTGGT
AGGCTCACCTCCAGGATATGTAGGACATGAAGAAGGGGGACAGTTAACAGAGCCCATTAGAAGGCGCCCTTATTCTGTTG
TACTTTTTGATGAGATTGAAAAAGCCCATCCCGATGTATTTAATATCCTTCTTCAGATCCTGGAAGATGGTCATTTGACC
GATACCCATGGGCGCAGAGTTGATTTCAAGAATACTGTTGTTATAATGACTTCAAATGTTGGGGCTAATTTTATCGAAAA
GCAGTCAAGGTTAGGCTTTAAAGCCGGAAATGATGAAAAACAAAATTACGAAGATATGAAGGATAAGTTAATGTCAGATT
TAAGGAGGACCTTCAGGCCCGAGTTTTTAAACAGGGTTGATGAAATTATTGTCTTCCATGCTCTAAACAGGGATCATATT
AAGCAGATTGTAGATCTGATGCTGGATGATGTTAAAAAACGCCTTGAGGACAAGGAAATTGATATTGAAGTTACTGAAGG
AGCAAAACATGTTCTTGCTGAAAAAGGGTTTGACTCAGAATTTGGAGCCCGTCCTTTGAGACGAACAATTCAGCGAATGG
TTGAAAACCCATTATCTGAAAAGATCCTGGAAGGAAAAGTTAAAGAAGGGGATAAAGTTGTTGTCGATGAACAGGATGGG
AAAGTAGTCGTGGGCAAATGA

Upstream 100 bases:

>100_bases
TCTACAGAAATTAGAGGGGAAAGAACTGACCCCAACCGAAAGGGATATTAAAAGAGCTGAATTAATTAAGACGAGATTAA
ATATGTAAGGAGGAGATAAA

Downstream 100 bases:

>100_bases
CCCGGTTTATTGTTGTAAAATCATGACAAAAATGTTATAATGAAAATATCACTATATTTCGGGAGTTAAAGAATTATGCC
CAGACCTAAAACCTATTATA

Product: ATPase AAA-2 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 806; Mature: 806

Protein sequence:

>806_residues
MFGRFTERARKVLSLAEKEAVGFKHNYVGTEHILLGLVKEGQGVAAKALKDVGISEEKVKEQITKLIGEGNQEVSGPISL
TPRSKKVLNLALDEARRLGHNYIGTEHILLGLIREGEGVAVRILANLNNGDLQNIREQVIELLGGKGNTRHQDGTRRSET
PNLDEYSRDLTKLADQVKLDPVIGREKEIERVIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVDESVPDVLLNKRVV
ALDLSSIVAGSKYRGEFEKRLKAVMNDIVKSGNIILFIDELHTLVGAGAAEGAIDAANILKPALARGELQAIGATTLDEY
RKYIEKDPALERRFQSILVEEPTPEETIEILKGLRDPYEAHHKVKISDEAIKAAVNLSHRYITDRFLPDKAIDLIDEAAS
RVRLGSDTRPPELKDLNKKLEEVKKEKEAAVKNQEFEKAAELRDKEKELEKEFENIQEKWEKEKEKSESTVTTEEIAEIV
SSWTGIPVTKLEQAETAKLLHLEEELHKRVVGQDEAIQAVSQAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
AMFNDEETMVRIDMSEYMEKHAVSRLVGSPPGYVGHEEGGQLTEPIRRRPYSVVLFDEIEKAHPDVFNILLQILEDGHLT
DTHGRRVDFKNTVVIMTSNVGANFIEKQSRLGFKAGNDEKQNYEDMKDKLMSDLRRTFRPEFLNRVDEIIVFHALNRDHI
KQIVDLMLDDVKKRLEDKEIDIEVTEGAKHVLAEKGFDSEFGARPLRRTIQRMVENPLSEKILEGKVKEGDKVVVDEQDG
KVVVGK

Sequences:

>Translated_806_residues
MFGRFTERARKVLSLAEKEAVGFKHNYVGTEHILLGLVKEGQGVAAKALKDVGISEEKVKEQITKLIGEGNQEVSGPISL
TPRSKKVLNLALDEARRLGHNYIGTEHILLGLIREGEGVAVRILANLNNGDLQNIREQVIELLGGKGNTRHQDGTRRSET
PNLDEYSRDLTKLADQVKLDPVIGREKEIERVIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVDESVPDVLLNKRVV
ALDLSSIVAGSKYRGEFEKRLKAVMNDIVKSGNIILFIDELHTLVGAGAAEGAIDAANILKPALARGELQAIGATTLDEY
RKYIEKDPALERRFQSILVEEPTPEETIEILKGLRDPYEAHHKVKISDEAIKAAVNLSHRYITDRFLPDKAIDLIDEAAS
RVRLGSDTRPPELKDLNKKLEEVKKEKEAAVKNQEFEKAAELRDKEKELEKEFENIQEKWEKEKEKSESTVTTEEIAEIV
SSWTGIPVTKLEQAETAKLLHLEEELHKRVVGQDEAIQAVSQAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
AMFNDEETMVRIDMSEYMEKHAVSRLVGSPPGYVGHEEGGQLTEPIRRRPYSVVLFDEIEKAHPDVFNILLQILEDGHLT
DTHGRRVDFKNTVVIMTSNVGANFIEKQSRLGFKAGNDEKQNYEDMKDKLMSDLRRTFRPEFLNRVDEIIVFHALNRDHI
KQIVDLMLDDVKKRLEDKEIDIEVTEGAKHVLAEKGFDSEFGARPLRRTIQRMVENPLSEKILEGKVKEGDKVVVDEQDG
KVVVGK
>Mature_806_residues
MFGRFTERARKVLSLAEKEAVGFKHNYVGTEHILLGLVKEGQGVAAKALKDVGISEEKVKEQITKLIGEGNQEVSGPISL
TPRSKKVLNLALDEARRLGHNYIGTEHILLGLIREGEGVAVRILANLNNGDLQNIREQVIELLGGKGNTRHQDGTRRSET
PNLDEYSRDLTKLADQVKLDPVIGREKEIERVIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVDESVPDVLLNKRVV
ALDLSSIVAGSKYRGEFEKRLKAVMNDIVKSGNIILFIDELHTLVGAGAAEGAIDAANILKPALARGELQAIGATTLDEY
RKYIEKDPALERRFQSILVEEPTPEETIEILKGLRDPYEAHHKVKISDEAIKAAVNLSHRYITDRFLPDKAIDLIDEAAS
RVRLGSDTRPPELKDLNKKLEEVKKEKEAAVKNQEFEKAAELRDKEKELEKEFENIQEKWEKEKEKSESTVTTEEIAEIV
SSWTGIPVTKLEQAETAKLLHLEEELHKRVVGQDEAIQAVSQAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
AMFNDEETMVRIDMSEYMEKHAVSRLVGSPPGYVGHEEGGQLTEPIRRRPYSVVLFDEIEKAHPDVFNILLQILEDGHLT
DTHGRRVDFKNTVVIMTSNVGANFIEKQSRLGFKAGNDEKQNYEDMKDKLMSDLRRTFRPEFLNRVDEIIVFHALNRDHI
KQIVDLMLDDVKKRLEDKEIDIEVTEGAKHVLAEKGFDSEFGARPLRRTIQRMVENPLSEKILEGKVKEGDKVVVDEQDG
KVVVGK

Specific function: Competence gene repressor; required for cell growth at high temperature. Negative regulator of comK expression. May interact with MecA to negatively regulate comK [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=303, Percent_Identity=37.953795379538, Blast_Score=199, Evalue=6e-51,
Organism=Escherichia coli, GI1788943, Length=867, Percent_Identity=48.3275663206459, Blast_Score=776, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=411, Percent_Identity=40.8759124087591, Blast_Score=290, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6320464, Length=749, Percent_Identity=46.328437917223, Blast_Score=650, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=879, Percent_Identity=39.8179749715586, Blast_Score=595, Evalue=1e-170,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 90442; Mature: 90442

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGRFTERARKVLSLAEKEAVGFKHNYVGTEHILLGLVKEGQGVAAKALKDVGISEEKVK
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHH
EQITKLIGEGNQEVSGPISLTPRSKKVLNLALDEARRLGHNYIGTEHILLGLIREGEGVA
HHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEE
VRILANLNNGDLQNIREQVIELLGGKGNTRHQDGTRRSETPNLDEYSRDLTKLADQVKLD
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
PVIGREKEIERVIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVDESVPDVLLNKRVV
CCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHCCEEE
ALDLSSIVAGSKYRGEFEKRLKAVMNDIVKSGNIILFIDELHTLVGAGAAEGAIDAANIL
EEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCHHHHHH
KPALARGELQAIGATTLDEYRKYIEKDPALERRFQSILVEEPTPEETIEILKGLRDPYEA
HHHHHCCCHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHC
HHKVKISDEAIKAAVNLSHRYITDRFLPDKAIDLIDEAASRVRLGSDTRPPELKDLNKKL
CCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
EEVKKEKEAAVKNQEFEKAAELRDKEKELEKEFENIQEKWEKEKEKSESTVTTEEIAEIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SSWTGIPVTKLEQAETAKLLHLEEELHKRVVGQDEAIQAVSQAVRRARAGLKDPKRPIGS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
FIFLGPTGVGKTELARALAEAMFNDEETMVRIDMSEYMEKHAVSRLVGSPPGYVGHEEGG
EEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
QLTEPIRRRPYSVVLFDEIEKAHPDVFNILLQILEDGHLTDTHGRRVDFKNTVVIMTSNV
CHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEECCCEEEEEECCC
GANFIEKQSRLGFKAGNDEKQNYEDMKDKLMSDLRRTFRPEFLNRVDEIIVFHALNRDHI
CCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHH
KQIVDLMLDDVKKRLEDKEIDIEVTEGAKHVLAEKGFDSEFGARPLRRTIQRMVENPLSE
HHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHH
KILEGKVKEGDKVVVDEQDGKVVVGK
HHHHCCCCCCCEEEEECCCCEEEECC
>Mature Secondary Structure
MFGRFTERARKVLSLAEKEAVGFKHNYVGTEHILLGLVKEGQGVAAKALKDVGISEEKVK
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHH
EQITKLIGEGNQEVSGPISLTPRSKKVLNLALDEARRLGHNYIGTEHILLGLIREGEGVA
HHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEE
VRILANLNNGDLQNIREQVIELLGGKGNTRHQDGTRRSETPNLDEYSRDLTKLADQVKLD
EEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
PVIGREKEIERVIQVLSRRTKNNPVLIGEPGVGKTAIVEGLAQRIVDESVPDVLLNKRVV
CCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCHHHHHCCEEE
ALDLSSIVAGSKYRGEFEKRLKAVMNDIVKSGNIILFIDELHTLVGAGAAEGAIDAANIL
EEEHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCCHHHHHH
KPALARGELQAIGATTLDEYRKYIEKDPALERRFQSILVEEPTPEETIEILKGLRDPYEA
HHHHHCCCHHHHCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHC
HHKVKISDEAIKAAVNLSHRYITDRFLPDKAIDLIDEAASRVRLGSDTRPPELKDLNKKL
CCEEEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
EEVKKEKEAAVKNQEFEKAAELRDKEKELEKEFENIQEKWEKEKEKSESTVTTEEIAEIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
SSWTGIPVTKLEQAETAKLLHLEEELHKRVVGQDEAIQAVSQAVRRARAGLKDPKRPIGS
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
FIFLGPTGVGKTELARALAEAMFNDEETMVRIDMSEYMEKHAVSRLVGSPPGYVGHEEGG
EEEECCCCCCHHHHHHHHHHHHHCCCHHEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCC
QLTEPIRRRPYSVVLFDEIEKAHPDVFNILLQILEDGHLTDTHGRRVDFKNTVVIMTSNV
CHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHHCCCCCCCCCCEEECCCEEEEEECCC
GANFIEKQSRLGFKAGNDEKQNYEDMKDKLMSDLRRTFRPEFLNRVDEIIVFHALNRDHI
CCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHH
KQIVDLMLDDVKKRLEDKEIDIEVTEGAKHVLAEKGFDSEFGARPLRRTIQRMVENPLSE
HHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHH
KILEGKVKEGDKVVVDEQDGKVVVGK
HHHHCCCCCCCEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8016066; 7584024; 9384377; 8195092 [H]