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The map label for this gene is pepC [H]

Identifier: 221230666

GI number: 221230666

Start: 2629994

End: 2631325

Strand: Reverse

Name: pepC [H]

Synonym: MLBr_02213

Alternate gene names: 221230666

Gene position: 2631325-2629994 (Counterclockwise)

Preceding gene: 221230667

Following gene: 221230665

Centisome position: 80.52

GC content: 62.54

Gene sequence:

>1332_bases
ATGCCGACCCTTGCGTCGACCACGTCGTCACCGACAGCCATGATGTTGGGCATGCCGGCTAGCGCTGCAGACCTCTGCGA
ATTCATCAACGCGTCCCCCTCGCCGTTTCATGTCTGCGCTACCGTGGCCGGTCGGCTACTCGACGCCGGTTACGCCGAAC
TCAGTGAGGTCGAGCGTTGGCCGGACCATCCGGGCCGATACTTCATCGTCCGCGCTGGCTCTCTGGTCGCTTGGAGTGCG
GGTCAGGGCGTCAAGGCACACGCCCCGTTTCGCATAGTGGGTGCGCATACCGACAGCCCGAATTTGCGAGTAAAGCAGCA
TCCGGACCTGCTGGTCGCCGGCTGGCGGGTGGTCGCATTGCAGCCCTATGGGGGAGCTTGGCTCAACTCCTGGCTGGATC
GCGATCTGGGTGTCAGTGGGCGGTTATCGGTGCGCTCAGCGGGTAAAGGTTCCGAGATCACCGATCGGCTTGTTCGGATA
GACGATCCGATTCTGCGGGTGCCGCAGTTGGCCATCCATTTAGCCGAGGATCGCAAGTCGCTCACCTTGGATCCGCAGCG
TCATGTAAACGCGGTATGGGGTGTCGGCGACAAAGCTGGGTCGTTGTTGGAGTACGTTGCTGAGCGCACCGGAGTGGCTG
TGGCCGACGTGTTGGCTGTCGACTTGATGACGCATGATCTGGTCCCGTCGATGGTGATCGGTGCCGATGCCAACCTGCTC
AGTGCACCCCGGCTGGATAACCAGGTCAGCTGCTATGCGGGCATGGAGGCTTTACTGGCCTCGGTGCCGCACGACTGCCT
CCCCGTGTTGGCGCTCTTTGACCATGAGGAAGTGGGTTCGACCTCAGACCGTGGTGCACGGTCAAACCTGCTGAGCACTG
TTTTGGAACGTATCGTGCTAGCGGCCGGTGGCGGCCGGGACGACTACCTGCGACGGTTGCCCGCTTCGCTGTTGGTCTCA
GCCGATATGGCGCACGCCACCCACCCGAATTACCCGGAGTGTCACGAACCCAGCCATCTCATTGAGGTCAACGCGGGCCC
GGTGCTCAAGGTGCACCCGAATCTGCGGTATGCCACCGATGGGCGCACGGCAGCTGCGTTCGAGGTGGCCTGCCAGCAAG
CCGGGGTCAGATTGCAGCGTTACGAGCACCGCGCCGACCGGCCGTGTGGTTCGACGATCGGGCCACTGGCTTCGGCTCGG
ACCGGTATTCCCACCGTCGATGTCGGTGCTGCCCAACTTGCGATGCACTCGGCACGGGAATTGATGGGTGCTCACGACGT
GGCTGTCTACTCTGCCGCGCTGCAGGCGTTCTTTTCTGCCGATTTGTTCTAA

Upstream 100 bases:

>100_bases
GTGCACAGTTGCCTCGCCGCTAATGTCGATGGTGACTCCAAGGAAGATCGCGGTAGACGTCACCGGCGCAAGTATGGATT
GCAGCTGAAACGGAGTTACT

Downstream 100 bases:

>100_bases
AGGCATAGGTTCTGCTGATATAGCGCTCAACGTGGAGATGGTCACATTCCAGTGCGGCGATCCAGCGAAGGTAGCCCGTT
GGGGTCGTGCACTAACGTGC

Product: putative aminopeptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MPTLASTTSSPTAMMLGMPASAADLCEFINASPSPFHVCATVAGRLLDAGYAELSEVERWPDHPGRYFIVRAGSLVAWSA
GQGVKAHAPFRIVGAHTDSPNLRVKQHPDLLVAGWRVVALQPYGGAWLNSWLDRDLGVSGRLSVRSAGKGSEITDRLVRI
DDPILRVPQLAIHLAEDRKSLTLDPQRHVNAVWGVGDKAGSLLEYVAERTGVAVADVLAVDLMTHDLVPSMVIGADANLL
SAPRLDNQVSCYAGMEALLASVPHDCLPVLALFDHEEVGSTSDRGARSNLLSTVLERIVLAAGGGRDDYLRRLPASLLVS
ADMAHATHPNYPECHEPSHLIEVNAGPVLKVHPNLRYATDGRTAAAFEVACQQAGVRLQRYEHRADRPCGSTIGPLASAR
TGIPTVDVGAAQLAMHSARELMGAHDVAVYSAALQAFFSADLF

Sequences:

>Translated_443_residues
MPTLASTTSSPTAMMLGMPASAADLCEFINASPSPFHVCATVAGRLLDAGYAELSEVERWPDHPGRYFIVRAGSLVAWSA
GQGVKAHAPFRIVGAHTDSPNLRVKQHPDLLVAGWRVVALQPYGGAWLNSWLDRDLGVSGRLSVRSAGKGSEITDRLVRI
DDPILRVPQLAIHLAEDRKSLTLDPQRHVNAVWGVGDKAGSLLEYVAERTGVAVADVLAVDLMTHDLVPSMVIGADANLL
SAPRLDNQVSCYAGMEALLASVPHDCLPVLALFDHEEVGSTSDRGARSNLLSTVLERIVLAAGGGRDDYLRRLPASLLVS
ADMAHATHPNYPECHEPSHLIEVNAGPVLKVHPNLRYATDGRTAAAFEVACQQAGVRLQRYEHRADRPCGSTIGPLASAR
TGIPTVDVGAAQLAMHSARELMGAHDVAVYSAALQAFFSADLF
>Mature_442_residues
PTLASTTSSPTAMMLGMPASAADLCEFINASPSPFHVCATVAGRLLDAGYAELSEVERWPDHPGRYFIVRAGSLVAWSAG
QGVKAHAPFRIVGAHTDSPNLRVKQHPDLLVAGWRVVALQPYGGAWLNSWLDRDLGVSGRLSVRSAGKGSEITDRLVRID
DPILRVPQLAIHLAEDRKSLTLDPQRHVNAVWGVGDKAGSLLEYVAERTGVAVADVLAVDLMTHDLVPSMVIGADANLLS
APRLDNQVSCYAGMEALLASVPHDCLPVLALFDHEEVGSTSDRGARSNLLSTVLERIVLAAGGGRDDYLRRLPASLLVSA
DMAHATHPNYPECHEPSHLIEVNAGPVLKVHPNLRYATDGRTAAAFEVACQQAGVRLQRYEHRADRPCGSTIGPLASART
GIPTVDVGAAQLAMHSARELMGAHDVAVYSAALQAFFSADLF

Specific function: Unknown

COG id: COG1362

COG function: function code E; Aspartyl aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M18 family [H]

Homologues:

Organism=Homo sapiens, GI156416028, Length=456, Percent_Identity=35.9649122807018, Blast_Score=267, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17552916, Length=450, Percent_Identity=34.2222222222222, Blast_Score=242, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6321905, Length=459, Percent_Identity=32.8976034858388, Blast_Score=256, Evalue=6e-69,
Organism=Saccharomyces cerevisiae, GI6322746, Length=452, Percent_Identity=30.7522123893805, Blast_Score=203, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022984
- InterPro:   IPR001948 [H]

Pfam domain/function: PF02127 Peptidase_M18 [H]

EC number: NA

Molecular weight: Translated: 47273; Mature: 47142

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLASTTSSPTAMMLGMPASAADLCEFINASPSPFHVCATVAGRLLDAGYAELSEVERW
CCCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHC
PDHPGRYFIVRAGSLVAWSAGQGVKAHAPFRIVGAHTDSPNLRVKQHPDLLVAGWRVVAL
CCCCCCEEEEECCCEEEEECCCCCCCCCCEEEEEECCCCCCCEEECCCCEEEECEEEEEE
QPYGGAWLNSWLDRDLGVSGRLSVRSAGKGSEITDRLVRIDDPILRVPQLAIHLAEDRKS
CCCCCHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
LTLDPQRHVNAVWGVGDKAGSLLEYVAERTGVAVADVLAVDLMTHDLVPSMVIGADANLL
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SAPRLDNQVSCYAGMEALLASVPHDCLPVLALFDHEEVGSTSDRGARSNLLSTVLERIVL
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHH
AAGGGRDDYLRRLPASLLVSADMAHATHPNYPECHEPSHLIEVNAGPVLKVHPNLRYATD
HCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEECCCCEEECC
GRTAAAFEVACQQAGVRLQRYEHRADRPCGSTIGPLASARTGIPTVDVGAAQLAMHSARE
CCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHH
LMGAHDVAVYSAALQAFFSADLF
HHCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PTLASTTSSPTAMMLGMPASAADLCEFINASPSPFHVCATVAGRLLDAGYAELSEVERW
CCCCCCCCCCCEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHC
PDHPGRYFIVRAGSLVAWSAGQGVKAHAPFRIVGAHTDSPNLRVKQHPDLLVAGWRVVAL
CCCCCCEEEEECCCEEEEECCCCCCCCCCEEEEEECCCCCCCEEECCCCEEEECEEEEEE
QPYGGAWLNSWLDRDLGVSGRLSVRSAGKGSEITDRLVRIDDPILRVPQLAIHLAEDRKS
CCCCCHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCC
LTLDPQRHVNAVWGVGDKAGSLLEYVAERTGVAVADVLAVDLMTHDLVPSMVIGADANLL
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
SAPRLDNQVSCYAGMEALLASVPHDCLPVLALFDHEEVGSTSDRGARSNLLSTVLERIVL
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHHH
AAGGGRDDYLRRLPASLLVSADMAHATHPNYPECHEPSHLIEVNAGPVLKVHPNLRYATD
HCCCCHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEECCCCEEECC
GRTAAAFEVACQQAGVRLQRYEHRADRPCGSTIGPLASARTGIPTVDVGAAQLAMHSARE
CCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHH
LMGAHDVAVYSAALQAFFSADLF
HHCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]