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The map label for this gene is ilvH

Identifier: 221230379

GI number: 221230379

Start: 2043701

End: 2044210

Strand: Reverse

Name: ilvH

Synonym: MLBr_01695

Alternate gene names: 221230379

Gene position: 2044210-2043701 (Counterclockwise)

Preceding gene: 221230380

Following gene: 221230378

Centisome position: 62.55

GC content: 58.24

Gene sequence:

>510_bases
ATGGTAGGGTTGCCAACGCACACCTTGTCGGTTCTGGTCGAGGACACTCCCGGCGTGCTCGCGCGGGTGGCGGCACTGTT
CTCTCGGCGCGGTTTCAATATTGAGTCGTTGGCTGTCGGTGCTACTGAGTGCAAGACTATGTCGCGAATGACCATCGTTG
TCTCTGCCGAGGAGACCCCGCTCGAGCAGGTCACCAAGCAGCTGCACAAGTTGATTAACGTCATCAAGGTTGTTGAGCAA
GAGGCTGACAACTCGCTGTCCCGCGAGCTGGCGTTGATCAAGGTGCGGGCCGAAGCTGGTACCCGCAGCCAGGTAATCGA
AGCGGTACACTTGTTCCGCGCCAGGGTTATTGATGTATCGCTCGAGTCACTGACTGTCGAGGCCACTGGTGACTGCAGCA
AAATTGAGGCGTTGCTGCGTGTGCTGGAGCCTTTCGGCGTACGAGAAATCGTCCAATCGGGAGTGGTCTCGTTATCTCGC
GGTCCGCGCGGTATCGGCACAGTCAGGTAG

Upstream 100 bases:

>100_bases
CCGCGGTATCCGCCCGCTCTTTGATGACGAAAGCGAAGGGCATGTTTGACTGTGCGTCGGCGACGATGCAGAGCCTAGCG
ATGAGGAGGAATGGCGCATA

Downstream 100 bases:

>100_bases
CTAACACGAAGGAGATAGTCACGTGGCAGACGTTTTGGATGAGTCACTATCATTGTTCTACGACGACAATGCAGATCTGT
CGATCATTCAGCGACGCAAA

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MVGLPTHTLSVLVEDTPGVLARVAALFSRRGFNIESLAVGATECKTMSRMTIVVSAEETPLEQVTKQLHKLINVIKVVEQ
EADNSLSRELALIKVRAEAGTRSQVIEAVHLFRARVIDVSLESLTVEATGDCSKIEALLRVLEPFGVREIVQSGVVSLSR
GPRGIGTVR

Sequences:

>Translated_169_residues
MVGLPTHTLSVLVEDTPGVLARVAALFSRRGFNIESLAVGATECKTMSRMTIVVSAEETPLEQVTKQLHKLINVIKVVEQ
EADNSLSRELALIKVRAEAGTRSQVIEAVHLFRARVIDVSLESLTVEATGDCSKIEALLRVLEPFGVREIVQSGVVSLSR
GPRGIGTVR
>Mature_169_residues
MVGLPTHTLSVLVEDTPGVLARVAALFSRRGFNIESLAVGATECKTMSRMTIVVSAEETPLEQVTKQLHKLINVIKVVEQ
EADNSLSRELALIKVRAEAGTRSQVIEAVHLFRARVIDVSLESLTVEATGDCSKIEALLRVLEPFGVREIVQSGVVSLSR
GPRGIGTVR

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain

Homologues:

Organism=Escherichia coli, GI1786266, Length=156, Percent_Identity=42.9487179487179, Blast_Score=122, Evalue=9e-30,
Organism=Saccharomyces cerevisiae, GI6319837, Length=205, Percent_Identity=30.2439024390244, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ILVH_MYCLE (O33113)

Other databases:

- EMBL:   Z99263
- EMBL:   AL583923
- PIR:   T45414
- RefSeq:   NP_302165.1
- ProteinModelPortal:   O33113
- SMR:   O33113
- EnsemblBacteria:   EBMYCT00000028035
- GeneID:   910799
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1695
- NMPDR:   fig|272631.1.peg.1037
- Leproma:   ML1695
- GeneTree:   EBGT00050000016800
- HOGENOM:   HBG335310
- OMA:   IERELAM
- ProtClustDB:   PRK11895
- BioCyc:   MLEP272631:ML1695-MONOMER
- BRENDA:   2.2.1.6
- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912
- TIGRFAMs:   TIGR00119

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C

EC number: =2.2.1.6

Molecular weight: Translated: 18285; Mature: 18285

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGLPTHTLSVLVEDTPGVLARVAALFSRRGFNIESLAVGATECKTMSRMTIVVSAEETP
CCCCCCHHHEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHEEEEEECCCCC
LEQVTKQLHKLINVIKVVEQEADNSLSRELALIKVRAEAGTRSQVIEAVHLFRARVIDVS
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHEEE
LESLTVEATGDCSKIEALLRVLEPFGVREIVQSGVVSLSRGPRGIGTVR
HHHEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MVGLPTHTLSVLVEDTPGVLARVAALFSRRGFNIESLAVGATECKTMSRMTIVVSAEETP
CCCCCCHHHEEEECCCCHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHEEEEEECCCCC
LEQVTKQLHKLINVIKVVEQEADNSLSRELALIKVRAEAGTRSQVIEAVHLFRARVIDVS
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHEEE
LESLTVEATGDCSKIEALLRVLEPFGVREIVQSGVVSLSRGPRGIGTVR
HHHEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11234002