Click here to switch to the map view.

The map label for this gene is yabD [H]

Identifier: 221229513

GI number: 221229513

Start: 313926

End: 314714

Strand: Direct

Name: yabD [H]

Synonym: MLBr_00239

Alternate gene names: 221229513

Gene position: 313926-314714 (Clockwise)

Preceding gene: 221229510

Following gene: 221229514

Centisome position: 9.61

GC content: 60.46

Gene sequence:

>789_bases
TTGGTCGATGCCCATACCCACCTCGACGCGTGCGGCGCCCGCGACGCCGATGACGTGAATGCCATCGTTGAGCGAGCCGC
GGCTGTAGGTGTGGTTGCGGTCGTCACCGTCGCAGACGACTTGGAATCTGCGCGTTGGGTCATTGCTGCCGCCGGGTGGG
ACCGGCGGGTGTACGCGGCGGTGGCGTTGCACCCGACGCGAGCAAACTCGCTCACCAGTGCCGCTCGGGCCAAGATTGAA
CAACTGGCGGCCCATCCGCGGATGGTGGCTGTCGGCGAGACCGGTATGGATTTGTATTGGCCCGGCCGCCTCGACAGCTG
TGCCCCACCTGACGTGCAGCGCGAGGCGTTCGCATGGCATATTGATCTTGCCAAGCGATGTGGCAAACCGCTGATGATCC
ACAACCGGCAAGCTGACGCGGAAGTGCTTGACGTCTTGCGTGCTGAGGGCGCCCCCGAGCAAGTAATTTTTCATTGTTTT
TCGTCTAATGCTGCGATGGCCCGCCGCTGCGTAGACGCCGGGTGGATGCTCAGCTTGTCCGGGACGGTGAGTTTCCGTAA
TGCTCGTCCCCTGCGGGAAGCTGTTCCGTTGATCCCAGCGCAACAGCTTCTGGTGGAAACCGATGCGCCATTTTTGACCC
CGCATCCCCACCGGGGTCTAGCTAACGAACCTTACTGCCTTCCTTACACTGTTAGAGCCGTTGCTGAATTGGTTGAACGT
TCCCCAGAAGAGCTGGCGCAAATCACCACTAGCAATGCTCTACGCGTGTACAAGCTAGGATCTGTATAG

Upstream 100 bases:

>100_bases
ATAGGGCCTCATCGAGACTCCACCCTATTGTGTGTGCGTGAGTTCTAACCGCCTAGTTAGACAACAAGACGCGCCTCCTG
CGCCGGAACCCCTGTCACCG

Downstream 100 bases:

>100_bases
GTTAGGTTGCCTAGCTCGCTCTCTCGCCATTACGGCGTAGATCGTAACTTGGCTAGCTCAGACGCGAGGGAGCTCCGGCG
TGATTTCCCTTACATCCTGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 262

Protein sequence:

>262_residues
MVDAHTHLDACGARDADDVNAIVERAAAVGVVAVVTVADDLESARWVIAAAGWDRRVYAAVALHPTRANSLTSAARAKIE
QLAAHPRMVAVGETGMDLYWPGRLDSCAPPDVQREAFAWHIDLAKRCGKPLMIHNRQADAEVLDVLRAEGAPEQVIFHCF
SSNAAMARRCVDAGWMLSLSGTVSFRNARPLREAVPLIPAQQLLVETDAPFLTPHPHRGLANEPYCLPYTVRAVAELVER
SPEELAQITTSNALRVYKLGSV

Sequences:

>Translated_262_residues
MVDAHTHLDACGARDADDVNAIVERAAAVGVVAVVTVADDLESARWVIAAAGWDRRVYAAVALHPTRANSLTSAARAKIE
QLAAHPRMVAVGETGMDLYWPGRLDSCAPPDVQREAFAWHIDLAKRCGKPLMIHNRQADAEVLDVLRAEGAPEQVIFHCF
SSNAAMARRCVDAGWMLSLSGTVSFRNARPLREAVPLIPAQQLLVETDAPFLTPHPHRGLANEPYCLPYTVRAVAELVER
SPEELAQITTSNALRVYKLGSV
>Mature_262_residues
MVDAHTHLDACGARDADDVNAIVERAAAVGVVAVVTVADDLESARWVIAAAGWDRRVYAAVALHPTRANSLTSAARAKIE
QLAAHPRMVAVGETGMDLYWPGRLDSCAPPDVQREAFAWHIDLAKRCGKPLMIHNRQADAEVLDVLRAEGAPEQVIFHCF
SSNAAMARRCVDAGWMLSLSGTVSFRNARPLREAVPLIPAQQLLVETDAPFLTPHPHRGLANEPYCLPYTVRAVAELVER
SPEELAQITTSNALRVYKLGSV

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=27.8195488721804, Blast_Score=91, Evalue=8e-19,
Organism=Homo sapiens, GI110349730, Length=266, Percent_Identity=27.8195488721804, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI226061853, Length=272, Percent_Identity=27.5735294117647, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI14042943, Length=273, Percent_Identity=23.8095238095238, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI226061614, Length=259, Percent_Identity=26.6409266409266, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI225903424, Length=216, Percent_Identity=28.2407407407407, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI226061595, Length=235, Percent_Identity=26.8085106382979, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1787342, Length=264, Percent_Identity=34.469696969697, Blast_Score=149, Evalue=1e-37,
Organism=Escherichia coli, GI87082439, Length=265, Percent_Identity=28.3018867924528, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI48994985, Length=255, Percent_Identity=29.4117647058824, Blast_Score=97, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI71980746, Length=266, Percent_Identity=29.3233082706767, Blast_Score=114, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17559024, Length=274, Percent_Identity=29.9270072992701, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17543026, Length=190, Percent_Identity=30.5263157894737, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565396, Length=194, Percent_Identity=28.3505154639175, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648690, Length=275, Percent_Identity=29.4545454545455, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI221330018, Length=274, Percent_Identity=24.8175182481752, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24586117, Length=208, Percent_Identity=27.8846153846154, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28456; Mature: 28456

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS01137 TATD_1 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDAHTHLDACGARDADDVNAIVERAAAVGVVAVVTVADDLESARWVIAAAGWDRRVYAA
CCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEHHHHCCCCEEEEECCCCCEEEEE
VALHPTRANSLTSAARAKIEQLAAHPRMVAVGETGMDLYWPGRLDSCAPPDVQREAFAWH
EEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCCCCCHHHHEEE
IDLAKRCGKPLMIHNRQADAEVLDVLRAEGAPEQVIFHCFSSNAAMARRCVDAGWMLSLS
EEHHHHCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEC
GTVSFRNARPLREAVPLIPAQQLLVETDAPFLTPHPHRGLANEPYCLPYTVRAVAELVER
CEEEECCCCCHHHHCCCCCHHHHHEECCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHC
SPEELAQITTSNALRVYKLGSV
CHHHHHHHHCCCCEEEEEECCC
>Mature Secondary Structure
MVDAHTHLDACGARDADDVNAIVERAAAVGVVAVVTVADDLESARWVIAAAGWDRRVYAA
CCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEHHHHCCCCEEEEECCCCCEEEEE
VALHPTRANSLTSAARAKIEQLAAHPRMVAVGETGMDLYWPGRLDSCAPPDVQREAFAWH
EEECCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCCCCCHHHHEEE
IDLAKRCGKPLMIHNRQADAEVLDVLRAEGAPEQVIFHCFSSNAAMARRCVDAGWMLSLS
EEHHHHCCCCEEEECCCCHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCEEEEEC
GTVSFRNARPLREAVPLIPAQQLLVETDAPFLTPHPHRGLANEPYCLPYTVRAVAELVER
CEEEECCCCCHHHHCCCCCHHHHHEECCCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHC
SPEELAQITTSNALRVYKLGSV
CHHHHHHHHCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]