Click here to switch to the map view.

The map label for this gene is rodA

Identifier: 221229360

GI number: 221229360

Start: 23660

End: 25057

Strand: Reverse

Name: rodA

Synonym: MLBr_00019

Alternate gene names: 221229360

Gene position: 25057-23660 (Counterclockwise)

Preceding gene: 221229361

Following gene: 221229359

Centisome position: 0.77

GC content: 56.58

Gene sequence:

>1398_bases
ATGACAACGCAACTTCAGCCGGTGGTCACAGTGACACCTCCGTTGCCCACGCGACGTAACGCTGAGCTGCTGCTACTTGG
CTTCGCCGCCGTGATCACCGTCGCCGCACTGGCCATCGTGGAAGCCAACCAAGAGAGAAACTTTCGTTGGTACCTGGCCG
GCTACGGGCTGATCTTCTGGTCATTGTTCGCATCCGCCCATCTAGCTATAAGACGTTTCGCTCCCTACACCGACCCGCTA
CTACTACCAATAGTGGCCTTGCTCAACGGACTGGGCCTGGTGATGATCCACCGACTCGACCTTGTTGATAACGACGTCAC
CGGTCACCATCACACCAGTGCGGCCCAACAGATGCTGTGGACCCTGGTCGGGGTGGCCGCATTTGTGCTGGTGATGACCG
TGTTAAAAGACCATCGCCAGCTCGCACGCTATGGCTACATATCCGGATTGACGGGTCTGGTTTTCTTGGCAATTCCCGCA
CCGCTGCCCGAACAAAACGGTGCTAAGATTTGGATCCGCTTTCCGGGTTTTTCGATTCAGCCCGCCGAATTTTCGAAGAT
TCTGTTGCTGATCTTCTTCGCAGCAGTGCTAGTCGCTAAACGCAGCCTGTTCACCAGCGCCGGTAAGCATTTAATAGGTA
TGACCCTGCCCCGGCCGCGAGACCTCGCGCCGTTACTGGCTGCCTGGGTGATCTCGGTAAGTGTGATGGTCTTCGAAAAG
GACCTCGGCACTTCGCTGCTGCTCTACGCATCGTTTCTGGTGGTGGTTTACCTCGCCACTCAGCGTCTCAGTTGGGTCAT
CATCGGCCTGGTGTTGTTCACTGCGGGAAGCACTATAGCATACTTCACTTTCGAACACATCCGGGTTCGCATGCAAGTGT
GGTGGGATCCCTTCACCAATCTCGATGTCGGTGGCTATCAGATTGTGCAATCGCTTTTTAGCTTCGCTACCGGAGGTATT
TTCGGCACCGGCCTGGGTAACGGTCAACCCGATGCCATACCTGCGGCCTCAACTGATTTCATTATCGCCGTATTCGGCGA
AGAGCTTGGATTGGTGGGCCTAGCTGCCCTTCTCATGCTCTACACGATTGTCATCGTCCGCGGCCTGCGCACGGCTATCG
CCACACGCGACAGTTTCGGTAAACTGTTGGCCGCAGGTCTGGCATCGACGCTGGCCATCCAACTGTTCATCGTCAGCGGT
GGCGTTACCACGCTCATTCCGCTGACCGGCTTGACCACACCGTGGATGTCTTACGGTGGATCGTCATTGCTGGCGAACTA
TGTGCTGCTGGCCATCCTGGCACGCATCTCGCATAGCGCTCGACATCCGTTACGCAGCCGCCCACACAACACGTCCCCGA
TCGCGGTGGCAAGTACCGAAGTGATCGAAAGGGTATGA

Upstream 100 bases:

>100_bases
CCGCAAGTACCGCGCCGACAACGCCGGTGGGCACCTCGCAGACGGTCACCATCCTTCCACCACCCCCACCCCAACCGGGC
ATCGACTGCCGGGCGGTGGC

Downstream 100 bases:

>100_bases
ACACCTCTCTCCGCCGAATCTCGGTGACCGTGATGGCGTTGATCGTGCTGCTGCTGCTCAACGCCACGGTAACGCAGGTG
TTCACCGCCGACGGACTGCG

Product: putative cell-division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTTQLQPVVTVTPPLPTRRNAELLLLGFAAVITVAALAIVEANQERNFRWYLAGYGLIFWSLFASAHLAIRRFAPYTDPL
LLPIVALLNGLGLVMIHRLDLVDNDVTGHHHTSAAQQMLWTLVGVAAFVLVMTVLKDHRQLARYGYISGLTGLVFLAIPA
PLPEQNGAKIWIRFPGFSIQPAEFSKILLLIFFAAVLVAKRSLFTSAGKHLIGMTLPRPRDLAPLLAAWVISVSVMVFEK
DLGTSLLLYASFLVVVYLATQRLSWVIIGLVLFTAGSTIAYFTFEHIRVRMQVWWDPFTNLDVGGYQIVQSLFSFATGGI
FGTGLGNGQPDAIPAASTDFIIAVFGEELGLVGLAALLMLYTIVIVRGLRTAIATRDSFGKLLAAGLASTLAIQLFIVSG
GVTTLIPLTGLTTPWMSYGGSSLLANYVLLAILARISHSARHPLRSRPHNTSPIAVASTEVIERV

Sequences:

>Translated_465_residues
MTTQLQPVVTVTPPLPTRRNAELLLLGFAAVITVAALAIVEANQERNFRWYLAGYGLIFWSLFASAHLAIRRFAPYTDPL
LLPIVALLNGLGLVMIHRLDLVDNDVTGHHHTSAAQQMLWTLVGVAAFVLVMTVLKDHRQLARYGYISGLTGLVFLAIPA
PLPEQNGAKIWIRFPGFSIQPAEFSKILLLIFFAAVLVAKRSLFTSAGKHLIGMTLPRPRDLAPLLAAWVISVSVMVFEK
DLGTSLLLYASFLVVVYLATQRLSWVIIGLVLFTAGSTIAYFTFEHIRVRMQVWWDPFTNLDVGGYQIVQSLFSFATGGI
FGTGLGNGQPDAIPAASTDFIIAVFGEELGLVGLAALLMLYTIVIVRGLRTAIATRDSFGKLLAAGLASTLAIQLFIVSG
GVTTLIPLTGLTTPWMSYGGSSLLANYVLLAILARISHSARHPLRSRPHNTSPIAVASTEVIERV
>Mature_464_residues
TTQLQPVVTVTPPLPTRRNAELLLLGFAAVITVAALAIVEANQERNFRWYLAGYGLIFWSLFASAHLAIRRFAPYTDPLL
LPIVALLNGLGLVMIHRLDLVDNDVTGHHHTSAAQQMLWTLVGVAAFVLVMTVLKDHRQLARYGYISGLTGLVFLAIPAP
LPEQNGAKIWIRFPGFSIQPAEFSKILLLIFFAAVLVAKRSLFTSAGKHLIGMTLPRPRDLAPLLAAWVISVSVMVFEKD
LGTSLLLYASFLVVVYLATQRLSWVIIGLVLFTAGSTIAYFTFEHIRVRMQVWWDPFTNLDVGGYQIVQSLFSFATGGIF
GTGLGNGQPDAIPAASTDFIIAVFGEELGLVGLAALLMLYTIVIVRGLRTAIATRDSFGKLLAAGLASTLAIQLFIVSGG
VTTLIPLTGLTTPWMSYGGSSLLANYVLLAILARISHSARHPLRSRPHNTSPIAVASTEVIERV

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family

Homologues:

Organism=Escherichia coli, GI1786277, Length=282, Percent_Identity=31.2056737588652, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1786853, Length=291, Percent_Identity=34.7079037800687, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSW_MYCLE (Q50186)

Other databases:

- EMBL:   Z70722
- EMBL:   AL583917
- PIR:   C86911
- PIR:   T10012
- RefSeq:   NP_301145.1
- EnsemblBacteria:   EBMYCT00000029322
- GeneID:   910311
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML0019
- NMPDR:   fig|272631.1.peg.17
- Leproma:   ML0019
- GeneTree:   EBGT00050000015955
- HOGENOM:   HBG729614
- OMA:   AAILMLY
- ProtClustDB:   CLSK790195
- BioCyc:   MLEP272631:ML0019-MONOMER
- InterPro:   IPR001182
- InterPro:   IPR018365

Pfam domain/function: PF01098 FTSW_RODA_SPOVE

EC number: NA

Molecular weight: Translated: 50469; Mature: 50338

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x22132d18)-; HASH(0x2175c744)-; HASH(0x21756874)-; HASH(0x217581d4)-; HASH(0x21756a9c)-; HASH(0x11f66454)-; HASH(0x2175e128)-; HASH(0x21757f28)-; HASH(0x2175b24c)-; HASH(0x2122ae84)-; HASH(0x21759908)-; HASH(0x216e3988)-; HASH(0x21756748)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTQLQPVVTVTPPLPTRRNAELLLLGFAAVITVAALAIVEANQERNFRWYLAGYGLIFW
CCCCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
SLFASAHLAIRRFAPYTDPLLLPIVALLNGLGLVMIHRLDLVDNDVTGHHHTSAAQQMLW
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TLVGVAAFVLVMTVLKDHRQLARYGYISGLTGLVFLAIPAPLPEQNGAKIWIRFPGFSIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCCCC
PAEFSKILLLIFFAAVLVAKRSLFTSAGKHLIGMTLPRPRDLAPLLAAWVISVSVMVFEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHEEEC
DLGTSLLLYASFLVVVYLATQRLSWVIIGLVLFTAGSTIAYFTFEHIRVRMQVWWDPFTN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHEEEEEEEECCCCC
LDVGGYQIVQSLFSFATGGIFGTGLGNGQPDAIPAASTDFIIAVFGEELGLVGLAALLML
CCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHH
YTIVIVRGLRTAIATRDSFGKLLAAGLASTLAIQLFIVSGGVTTLIPLTGLTTPWMSYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHEEHHHCCCCCHHHHCCC
SSLLANYVLLAILARISHSARHPLRSRPHNTSPIAVASTEVIERV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHCH
>Mature Secondary Structure 
TTQLQPVVTVTPPLPTRRNAELLLLGFAAVITVAALAIVEANQERNFRWYLAGYGLIFW
CCCCCCEEEECCCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHH
SLFASAHLAIRRFAPYTDPLLLPIVALLNGLGLVMIHRLDLVDNDVTGHHHTSAAQQMLW
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
TLVGVAAFVLVMTVLKDHRQLARYGYISGLTGLVFLAIPAPLPEQNGAKIWIRFPGFSIQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCCCC
PAEFSKILLLIFFAAVLVAKRSLFTSAGKHLIGMTLPRPRDLAPLLAAWVISVSVMVFEK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHEEEC
DLGTSLLLYASFLVVVYLATQRLSWVIIGLVLFTAGSTIAYFTFEHIRVRMQVWWDPFTN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHEEEEEEEECCCCC
LDVGGYQIVQSLFSFATGGIFGTGLGNGQPDAIPAASTDFIIAVFGEELGLVGLAALLML
CCCCHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHH
YTIVIVRGLRTAIATRDSFGKLLAAGLASTLAIQLFIVSGGVTTLIPLTGLTTPWMSYGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCHHEEHHHCCCCCHHHHCCC
SSLLANYVLLAILARISHSARHPLRSRPHNTSPIAVASTEVIERV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11234002