The gene/protein map for NC_011891 is currently unavailable.
Definition Anaeromyxobacter dehalogenans 2CP-1 chromosome, complete genome.
Accession NC_011891
Length 5,029,329

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The map label for this gene is cypB [H]

Identifier: 220917395

GI number: 220917395

Start: 2544331

End: 2545023

Strand: Reverse

Name: cypB [H]

Synonym: A2cp1_2295

Alternate gene names: 220917395

Gene position: 2545023-2544331 (Counterclockwise)

Preceding gene: 220917396

Following gene: 220917394

Centisome position: 50.6

GC content: 71.57

Gene sequence:

>693_bases
ATGACGCGCTCCTCCCTTCTGGTGATTTCACTGTTCGTGTCGCTGGCCGTCCCGCCCGCCGCCCGCGCGCAGGCGCCCGC
GGCCGCCCCGGCCAAGGGCAAGGACCTGTACGCGGTGTTCGAGACCTCGCGCGGCAAGATCGGCGTGAAGCTGCTGCCGG
CCGAGGCGCCGAAGACGGTCGAGAACTTCGTCCAGCTCGCCGAGGGCAAGAAGGCGTTCACCGACCCGCTCACCGGGCAG
CAGCGCAAGGCGCCGTACTTCGACGGCCTGCTGTTCCACCGCGTGATCCCCGGCTTCATGATCCAGGGCGGCGATCCGGC
CACGCGCGGCGCGCCGCTCGGCAGCTCGGCGCAGAAGAACCTCCCGTTCGGCGTCTCGGGGCCCGGCTACAAGTTCGAGG
ACGAGCTGCCGGCGCCCGGGACCCGCCTGTTCGAGAAGCCCTGCGTCCTCGCCATGGCGAACTCGGGCCCGAACACGAAC
GGCTCGCAGTTCTTCATCACCGAGGGCGCCGGCGACCGCGTGCCGCAGCTCGAGCCGCGGGCCTGCGACTCGAAGTCGGG
CGTGTGCGGCTACACGCGCTTCGGGCAGGGCGTGTGCGGCTGCGACCTGGTCGGCGGCATCGCCCGCGCCGGGAACTCGC
AGACGCGGCTGGTGAAGGTCACCATCACCGGCGAGCGCCCCACCTGCAAGTAG

Upstream 100 bases:

>100_bases
GGCGCCGCCAAGGGAGCCCGCAAGGGGACGCGCCCCCGGCGCTGAGGGGCGCCGTCTTTCCATTTGCCGGGGCTCCCACC
CGCGACTAGCATCCCGCGGC

Downstream 100 bases:

>100_bases
CGACAACCCGGGCCCGTGCGCGGGCCCGCCACCCGGCGGCGCGCCGGGAGAGGTGAACCATGGCCGAGGAGCTGTACGCG
ACGTTCAAGACGTCGATGGG

Product: cyclophilin type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase B; Cyclophilin ScCypB; Rotamase B; S-cyclophilin [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MTRSSLLVISLFVSLAVPPAARAQAPAAAPAKGKDLYAVFETSRGKIGVKLLPAEAPKTVENFVQLAEGKKAFTDPLTGQ
QRKAPYFDGLLFHRVIPGFMIQGGDPATRGAPLGSSAQKNLPFGVSGPGYKFEDELPAPGTRLFEKPCVLAMANSGPNTN
GSQFFITEGAGDRVPQLEPRACDSKSGVCGYTRFGQGVCGCDLVGGIARAGNSQTRLVKVTITGERPTCK

Sequences:

>Translated_230_residues
MTRSSLLVISLFVSLAVPPAARAQAPAAAPAKGKDLYAVFETSRGKIGVKLLPAEAPKTVENFVQLAEGKKAFTDPLTGQ
QRKAPYFDGLLFHRVIPGFMIQGGDPATRGAPLGSSAQKNLPFGVSGPGYKFEDELPAPGTRLFEKPCVLAMANSGPNTN
GSQFFITEGAGDRVPQLEPRACDSKSGVCGYTRFGQGVCGCDLVGGIARAGNSQTRLVKVTITGERPTCK
>Mature_229_residues
TRSSLLVISLFVSLAVPPAARAQAPAAAPAKGKDLYAVFETSRGKIGVKLLPAEAPKTVENFVQLAEGKKAFTDPLTGQQ
RKAPYFDGLLFHRVIPGFMIQGGDPATRGAPLGSSAQKNLPFGVSGPGYKFEDELPAPGTRLFEKPCVLAMANSGPNTNG
SQFFITEGAGDRVPQLEPRACDSKSGVCGYTRFGQGVCGCDLVGGIARAGNSQTRLVKVTITGERPTCK

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI24308049, Length=145, Percent_Identity=41.3793103448276, Blast_Score=92, Evalue=3e-19,
Organism=Homo sapiens, GI7706339, Length=180, Percent_Identity=38.3333333333333, Blast_Score=85, Evalue=5e-17,
Organism=Homo sapiens, GI64276486, Length=146, Percent_Identity=36.3013698630137, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI256017253, Length=132, Percent_Identity=42.4242424242424, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI221139811, Length=132, Percent_Identity=42.4242424242424, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI256017251, Length=132, Percent_Identity=42.4242424242424, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI10863927, Length=125, Percent_Identity=40.8, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI19557636, Length=172, Percent_Identity=32.5581395348837, Blast_Score=78, Evalue=7e-15,
Organism=Homo sapiens, GI209417936, Length=122, Percent_Identity=41.8032786885246, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI30102944, Length=122, Percent_Identity=41.8032786885246, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI219842199, Length=122, Percent_Identity=41.8032786885246, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI310129267, Length=184, Percent_Identity=32.6086956521739, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI310120620, Length=184, Percent_Identity=32.6086956521739, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI178057341, Length=122, Percent_Identity=40.9836065573771, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI4826932, Length=183, Percent_Identity=35.5191256830601, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI310110104, Length=181, Percent_Identity=33.1491712707182, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI45439316, Length=218, Percent_Identity=33.0275229357798, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI5031987, Length=180, Percent_Identity=33.8888888888889, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI303305009, Length=207, Percent_Identity=32.3671497584541, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI4505991, Length=123, Percent_Identity=39.8373983739837, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI5174637, Length=205, Percent_Identity=32.6829268292683, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI310127646, Length=125, Percent_Identity=36, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI310114371, Length=125, Percent_Identity=36, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI310119221, Length=125, Percent_Identity=36, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4758950, Length=123, Percent_Identity=39.0243902439024, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI42560244, Length=131, Percent_Identity=38.1679389312977, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI310132444, Length=123, Percent_Identity=38.2113821138211, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI310113152, Length=123, Percent_Identity=38.2113821138211, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI169164185, Length=122, Percent_Identity=36.0655737704918, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI169163623, Length=122, Percent_Identity=36.0655737704918, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI169163387, Length=124, Percent_Identity=34.6774193548387, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17539496, Length=196, Percent_Identity=34.6938775510204, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17551284, Length=182, Percent_Identity=37.9120879120879, Blast_Score=84, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17551282, Length=182, Percent_Identity=37.9120879120879, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17506311, Length=131, Percent_Identity=41.9847328244275, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17566266, Length=169, Percent_Identity=36.6863905325444, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17565860, Length=178, Percent_Identity=35.9550561797753, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17559074, Length=175, Percent_Identity=34.8571428571429, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17552784, Length=188, Percent_Identity=35.1063829787234, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17539498, Length=184, Percent_Identity=34.2391304347826, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71997782, Length=193, Percent_Identity=30.5699481865285, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17552780, Length=126, Percent_Identity=43.6507936507937, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17552782, Length=173, Percent_Identity=36.9942196531792, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323562, Length=176, Percent_Identity=34.6590909090909, Blast_Score=75, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6320510, Length=230, Percent_Identity=32.1739130434783, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320359, Length=185, Percent_Identity=36.2162162162162, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323246, Length=128, Percent_Identity=39.0625, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321848, Length=189, Percent_Identity=35.978835978836, Blast_Score=67, Evalue=2e-12,
Organism=Drosophila melanogaster, GI17986117, Length=131, Percent_Identity=38.9312977099237, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI19922912, Length=130, Percent_Identity=40, Blast_Score=77, Evalue=7e-15,
Organism=Drosophila melanogaster, GI19922376, Length=204, Percent_Identity=31.3725490196078, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45549139, Length=178, Percent_Identity=33.7078651685393, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24650807, Length=123, Percent_Identity=39.8373983739837, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24664125, Length=178, Percent_Identity=32.5842696629214, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21357783, Length=178, Percent_Identity=32.5842696629214, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17647301, Length=204, Percent_Identity=30.8823529411765, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 24129; Mature: 23998

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTRSSLLVISLFVSLAVPPAARAQAPAAAPAKGKDLYAVFETSRGKIGVKLLPAEAPKTV
CCCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHH
ENFVQLAEGKKAFTDPLTGQQRKAPYFDGLLFHRVIPGFMIQGGDPATRGAPLGSSAQKN
HHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCC
LPFGVSGPGYKFEDELPAPGTRLFEKPCVLAMANSGPNTNGSQFFITEGAGDRVPQLEPR
CCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCC
ACDSKSGVCGYTRFGQGVCGCDLVGGIARAGNSQTRLVKVTITGERPTCK
CCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCC
>Mature Secondary Structure 
TRSSLLVISLFVSLAVPPAARAQAPAAAPAKGKDLYAVFETSRGKIGVKLLPAEAPKTV
CCCHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCEEEEEEECCCCEEEEEEECCCCCHHH
ENFVQLAEGKKAFTDPLTGQQRKAPYFDGLLFHRVIPGFMIQGGDPATRGAPLGSSAQKN
HHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCC
LPFGVSGPGYKFEDELPAPGTRLFEKPCVLAMANSGPNTNGSQFFITEGAGDRVPQLEPR
CCCCCCCCCCCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCC
ACDSKSGVCGYTRFGQGVCGCDLVGGIARAGNSQTRLVKVTITGERPTCK
CCCCCCCCCCHHHHCCCCCCHHHHHHHHHCCCCCEEEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9025285 [H]