BacMap

Definition	Anaeromyxobacter dehalogenans 2CP-1 chromosome, complete genome.
Accession	NC_011891
Length	5,029,329

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The map label for this gene is cypB [H]

Identifier: 220917394

GI number: 220917394

Start: 2543765

End: 2544271

Strand: Reverse

Name: cypB [H]

Synonym: A2cp1_2294

Alternate gene names: 220917394

Gene position: 2544271-2543765 (Counterclockwise)

Preceding gene: 220917395

Following gene: 220917393

Centisome position: 50.59

GC content: 66.86

Gene sequence:

>507_bases
ATGGCCGAGGAGCTGTACGCGACGTTCAAGACGTCGATGGGCGACATCGTGGTGAAGCTGCTGCCGGAGAAGGCGCCCAA
GACCGTGAAGAACTTCGTGGACCTGGCCGAGGGTGCGCGCGAGTGGACCGACCCGCGCACCGGTCAGAAGGTGACGAAGC
CGCTCTACGACGGCACGGTGTTCCACCGCGTCATCCCGGACTTCATGATCCAGGGCGGTGATCCGCTCGGCACCGGCACC
GGCGGCCCCGGGTACCGGTTCGAGGACGAGATCGGCCCGGACAACGTGTTCTCGAAGCCCGGCCTGCTCGCCATGGCGAA
CGCCGGCCCGAACACGAACGGCTCGCAGTTCTTCATCACCGAGGTGGAGACGCCCTGGCTGAACAAGGGGCACACCATCT
TCGGCGAGGTGGTCAAGGGCGGGGAGCTCGTCCCGAAGATCACCCGCGCCGGCAACGCCAAGGTCAAGCTCGAGAAGGTC
ACCATCACCCGCGGCGCGCAGCCCTAG

Upstream 100 bases:

>100_bases
TGAAGGTCACCATCACCGGCGAGCGCCCCACCTGCAAGTAGCGACAACCCGGGCCCGTGCGCGGGCCCGCCACCCGGCGG
CGCGCCGGGAGAGGTGAACC

Downstream 100 bases:

>100_bases
CGCGCGCCGCCGCACGAAGGAACCCGGGCGCCCGCGCCCCCTCCGCCTCGAGCGGACGGGCGCGGGCGCGATCACCTCCA
TGGCCAGCAAGAAGAAGACC

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase B; Cyclophilin ScCypB; Rotamase B; S-cyclophilin [H]

Number of amino acids: Translated: 168; Mature: 167

Protein sequence:

>168_residues
MAEELYATFKTSMGDIVVKLLPEKAPKTVKNFVDLAEGAREWTDPRTGQKVTKPLYDGTVFHRVIPDFMIQGGDPLGTGT
GGPGYRFEDEIGPDNVFSKPGLLAMANAGPNTNGSQFFITEVETPWLNKGHTIFGEVVKGGELVPKITRAGNAKVKLEKV
TITRGAQP

Sequences:

>Translated_168_residues
MAEELYATFKTSMGDIVVKLLPEKAPKTVKNFVDLAEGAREWTDPRTGQKVTKPLYDGTVFHRVIPDFMIQGGDPLGTGT
GGPGYRFEDEIGPDNVFSKPGLLAMANAGPNTNGSQFFITEVETPWLNKGHTIFGEVVKGGELVPKITRAGNAKVKLEKV
TITRGAQP
>Mature_167_residues
AEELYATFKTSMGDIVVKLLPEKAPKTVKNFVDLAEGAREWTDPRTGQKVTKPLYDGTVFHRVIPDFMIQGGDPLGTGTG
GPGYRFEDEIGPDNVFSKPGLLAMANAGPNTNGSQFFITEVETPWLNKGHTIFGEVVKGGELVPKITRAGNAKVKLEKVT
ITRGAQP

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706339, Length=142, Percent_Identity=51.4084507042254, Blast_Score=135, Evalue=1e-32,
Organism=Homo sapiens, GI24308049, Length=152, Percent_Identity=50, Blast_Score=131, Evalue=3e-31,
Organism=Homo sapiens, GI64276486, Length=133, Percent_Identity=45.1127819548872, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI10863927, Length=163, Percent_Identity=41.7177914110429, Blast_Score=108, Evalue=2e-24,
Organism=Homo sapiens, GI19557636, Length=148, Percent_Identity=39.1891891891892, Blast_Score=107, Evalue=7e-24,
Organism=Homo sapiens, GI5031987, Length=163, Percent_Identity=41.7177914110429, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI4758950, Length=139, Percent_Identity=46.0431654676259, Blast_Score=104, Evalue=3e-23,
Organism=Homo sapiens, GI4826932, Length=133, Percent_Identity=48.1203007518797, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI256017253, Length=163, Percent_Identity=40.4907975460123, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI221139811, Length=163, Percent_Identity=40.4907975460123, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI256017251, Length=163, Percent_Identity=40.4907975460123, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI178057341, Length=163, Percent_Identity=39.8773006134969, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI4505991, Length=139, Percent_Identity=44.6043165467626, Blast_Score=100, Evalue=5e-22,
Organism=Homo sapiens, GI310129267, Length=158, Percent_Identity=39.2405063291139, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI310120620, Length=158, Percent_Identity=39.2405063291139, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI209417936, Length=164, Percent_Identity=39.6341463414634, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI30102944, Length=164, Percent_Identity=39.6341463414634, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI219842199, Length=164, Percent_Identity=39.6341463414634, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI42560244, Length=139, Percent_Identity=45.3237410071942, Blast_Score=97, Evalue=5e-21,
Organism=Homo sapiens, GI310110104, Length=158, Percent_Identity=38.6075949367089, Blast_Score=97, Evalue=6e-21,
Organism=Homo sapiens, GI169163387, Length=163, Percent_Identity=38.6503067484663, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI169164185, Length=163, Percent_Identity=38.6503067484663, Blast_Score=96, Evalue=1e-20,
Organism=Homo sapiens, GI169163623, Length=163, Percent_Identity=38.6503067484663, Blast_Score=96, Evalue=1e-20,
Organism=Homo sapiens, GI22547212, Length=142, Percent_Identity=44.3661971830986, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI7657473, Length=142, Percent_Identity=44.3661971830986, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI22547215, Length=142, Percent_Identity=44.3661971830986, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI310127646, Length=164, Percent_Identity=39.0243902439024, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI310114371, Length=164, Percent_Identity=39.0243902439024, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI310119221, Length=164, Percent_Identity=39.0243902439024, Blast_Score=94, Evalue=4e-20,
Organism=Homo sapiens, GI303305009, Length=149, Percent_Identity=40.2684563758389, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI5174637, Length=146, Percent_Identity=40.4109589041096, Blast_Score=94, Evalue=8e-20,
Organism=Homo sapiens, GI45439316, Length=149, Percent_Identity=38.9261744966443, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI5454154, Length=139, Percent_Identity=42.4460431654676, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI310132444, Length=163, Percent_Identity=37.4233128834356, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI310113152, Length=163, Percent_Identity=37.4233128834356, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI6631100, Length=145, Percent_Identity=42.0689655172414, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI150418007, Length=160, Percent_Identity=38.75, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI239751853, Length=160, Percent_Identity=33.75, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI113428306, Length=160, Percent_Identity=33.75, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI169214050, Length=160, Percent_Identity=33.75, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI20911035, Length=151, Percent_Identity=33.7748344370861, Blast_Score=82, Evalue=2e-16,
Organism=Homo sapiens, GI27735045, Length=143, Percent_Identity=32.8671328671329, Blast_Score=81, Evalue=3e-16,
Organism=Homo sapiens, GI310127745, Length=152, Percent_Identity=36.8421052631579, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI310119290, Length=152, Percent_Identity=36.8421052631579, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI310114540, Length=152, Percent_Identity=36.8421052631579, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI289803023, Length=164, Percent_Identity=31.0975609756098, Blast_Score=74, Evalue=8e-14,
Organism=Homo sapiens, GI14277126, Length=149, Percent_Identity=32.8859060402685, Blast_Score=67, Evalue=6e-12,
Organism=Escherichia coli, GI1786736, Length=152, Percent_Identity=37.5, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI1789763, Length=153, Percent_Identity=33.9869281045752, Blast_Score=71, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17539496, Length=160, Percent_Identity=43.125, Blast_Score=124, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17565860, Length=143, Percent_Identity=45.4545454545455, Blast_Score=116, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17506311, Length=167, Percent_Identity=42.5149700598802, Blast_Score=113, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI17566266, Length=145, Percent_Identity=46.2068965517241, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17552780, Length=161, Percent_Identity=44.7204968944099, Blast_Score=110, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17559074, Length=148, Percent_Identity=45.2702702702703, Blast_Score=107, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17551282, Length=159, Percent_Identity=45.9119496855346, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17551284, Length=159, Percent_Identity=45.9119496855346, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17539498, Length=143, Percent_Identity=41.958041958042, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71997782, Length=136, Percent_Identity=41.9117647058824, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17506307, Length=141, Percent_Identity=45.3900709219858, Blast_Score=103, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17552782, Length=144, Percent_Identity=43.75, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17552784, Length=139, Percent_Identity=44.6043165467626, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71980594, Length=146, Percent_Identity=37.6712328767123, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI71980590, Length=146, Percent_Identity=36.3013698630137, Blast_Score=95, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17532641, Length=142, Percent_Identity=38.0281690140845, Blast_Score=95, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17532643, Length=163, Percent_Identity=40.4907975460123, Blast_Score=93, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI115533296, Length=148, Percent_Identity=38.5135135135135, Blast_Score=81, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32563659, Length=150, Percent_Identity=32, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320359, Length=144, Percent_Identity=47.9166666666667, Blast_Score=117, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323562, Length=150, Percent_Identity=47.3333333333333, Blast_Score=115, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6323246, Length=145, Percent_Identity=47.5862068965517, Blast_Score=107, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6320510, Length=140, Percent_Identity=46.4285714285714, Blast_Score=103, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6321848, Length=163, Percent_Identity=39.2638036809816, Blast_Score=95, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6322492, Length=167, Percent_Identity=40.1197604790419, Blast_Score=92, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17986117, Length=145, Percent_Identity=46.8965517241379, Blast_Score=127, Evalue=3e-30,
Organism=Drosophila melanogaster, GI45549139, Length=154, Percent_Identity=43.5064935064935, Blast_Score=113, Evalue=7e-26,
Organism=Drosophila melanogaster, GI19922376, Length=145, Percent_Identity=37.2413793103448, Blast_Score=106, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24664125, Length=154, Percent_Identity=41.5584415584416, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21357783, Length=154, Percent_Identity=41.5584415584416, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24650807, Length=160, Percent_Identity=43.125, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17647301, Length=145, Percent_Identity=42.7586206896552, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI19922912, Length=140, Percent_Identity=47.1428571428571, Blast_Score=100, Evalue=8e-22,
Organism=Drosophila melanogaster, GI20130249, Length=144, Percent_Identity=43.75, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21357249, Length=134, Percent_Identity=39.5522388059701, Blast_Score=94, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24652460, Length=148, Percent_Identity=34.4594594594595, Blast_Score=89, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24586038, Length=164, Percent_Identity=38.4146341463415, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17136360, Length=143, Percent_Identity=38.4615384615385, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355677, Length=152, Percent_Identity=34.2105263157895, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 18176; Mature: 18045

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEELYATFKTSMGDIVVKLLPEKAPKTVKNFVDLAEGAREWTDPRTGQKVTKPLYDGTV
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHH
FHRVIPDFMIQGGDPLGTGTGGPGYRFEDEIGPDNVFSKPGLLAMANAGPNTNGSQFFIT
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEE
EVETPWLNKGHTIFGEVVKGGELVPKITRAGNAKVKLEKVTITRGAQP
ECCCCCCCCCCHHHHHHHCCCCCCHHHHCCCCCEEEEEEEEEECCCCC
>Mature Secondary Structure 
AEELYATFKTSMGDIVVKLLPEKAPKTVKNFVDLAEGAREWTDPRTGQKVTKPLYDGTV
CHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHH
FHRVIPDFMIQGGDPLGTGTGGPGYRFEDEIGPDNVFSKPGLLAMANAGPNTNGSQFFIT
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEE
EVETPWLNKGHTIFGEVVKGGELVPKITRAGNAKVKLEKVTITRGAQP
ECCCCCCCCCCHHHHHHHCCCCCCHHHHCCCCCEEEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9025285 [H]