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The map label for this gene is engA [H]

Identifier: 220917392

GI number: 220917392

Start: 2541359

End: 2542756

Strand: Reverse

Name: engA [H]

Synonym: A2cp1_2292

Alternate gene names: 220917392

Gene position: 2542756-2541359 (Counterclockwise)

Preceding gene: 220917393

Following gene: 220917391

Centisome position: 50.56

GC content: 72.96

Gene sequence:

>1398_bases
GTGACGGCCCCCCGCCCCGTGGTGGCGCTGGTGGGCCGCCCGAACGTCGGGAAGTCCACGCTGTTCAACCGGCTGGCCGG
CCGGCGCGTCGCGATCGTGGAGGACGTGCCCGGCGTGACCCGCGACCGCAACTACGCCGACGTGATCTGGGAAGGCCGCG
CCGTCTCGGTGGTGGACACCGGCGGCTTCGAGCCCGAGTCGCGCGACCGCCTCATGTCGCAGGTGCGCGAGCAGGCCCAG
CTCGCGGTGGACGAGGCCTCGGCGGTGGTGCTGGTGGTGGACGGCCGCGACGGCCTGACCGCGCTCGATCGCAACGTGGC
GGACCTGCTCCGGCGCGCCGGCAAGCCGCTGTTCGTCGCGGTGAACAAGGTGGACACCGCCCGCACCGAGGAGGACGTGC
CGCTGGCCGAGTTCTACGGGCTCGGGTTCGGCGAGGTGCACGCCGTCTCGGCCGAGCACGGGCGCGGCGTGTCCGGGCTG
GTGGACGCGATCGTCGAGAAGCTCGCGCTCCCGCCGCTCCCGCCGGCGCCGGAGGAGGCCGACGAGCCGCAGGAGGTCTC
GGAGGCGGAGCGGCCGGTCGGCGACATCCGGCTCGCCATCGTGGGCCGGCCCAACGTGGGCAAGAGCACGTTCGTGAACG
CGCTGCTCGGCGAGGAGCGCTTCGTGGTCTCCGACGTGCCCGGCACCACCCGCGACGCGATCGACTCGCTGGTCGCGCAC
AAGGGCCGGCGCTTCGTGGTCACCGACACCGCCGGGATCCGGCGCAAGCGCTCGATCGCGCAGAAGGTCGAGTCCTTCTC
GGTGGTCCGCGCCATGAAGGCGATGGATCAGGCCGAGGTGGTGGCGTGCCTCCTCGACGCGACCGAGGCCGGCGTCGAGC
AGGACGCTCGGCTCCTCGGCCTGGTGGCGGAGAAGGGCAAGGCGCTGGTCATCGTGGTGAACAAGTGGGACATCGCCGAG
CGCGAGGGCGCCACGCAGGACTGGTACCGCAAGGAGCTCACCAAGCGCCTGCCGTTCGTGGGCTTCGCGCCGATGCTGTT
CGTCTCCGCGAAGGAGCGGCGCGGCGTGCACCGCGTGCTGGAGAAGGCCGCGCGCCTGGTGGAGCAGTACCGGGCCCGGT
TCCCCACGCCGCAGCTCAACGAGCTGCTCGAGGCGCTGCAGGACGAGCACCCGGCCCCCATCGCCCGCGGGCGCCGGGTG
AAGCTCTACTACGTCGCCCAGGTGGCCTACGCCCCGCCCACGTTCGTCATCCAGGCCAACCACCCGGATGGCCTGACCGA
CCACTACCGCCGCTACATCGAGAACCGGTTCCGCGCCGCGTTCGGGCTGGAGGTGCCGATGCGCCTGGTGTTCAAGGAGC
GCCAGCACCGCGCCCGCCCGCGGCGGCCCCGCGAGTAG

Upstream 100 bases:

>100_bases
GGCTGGAGCGGCTGCTCGGGTGCAAGGTGTTCCTGTCGCTGACCGTGAAGGTGGACGAGCGCTGGAGCGAGCGCGAGGGC
GCGCTGAAGAGGTTCGGGCT

Downstream 100 bases:

>100_bases
GGCGGTCGGGCCGGCCCGGCGGGGCGGGCTTTCGCTTGACGCCCCCCGGGTAGCCGCCTAGATTGGCCCGGTTTTCCTCA
CATTTTCGCCGAGCACGCAC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MTAPRPVVALVGRPNVGKSTLFNRLAGRRVAIVEDVPGVTRDRNYADVIWEGRAVSVVDTGGFEPESRDRLMSQVREQAQ
LAVDEASAVVLVVDGRDGLTALDRNVADLLRRAGKPLFVAVNKVDTARTEEDVPLAEFYGLGFGEVHAVSAEHGRGVSGL
VDAIVEKLALPPLPPAPEEADEPQEVSEAERPVGDIRLAIVGRPNVGKSTFVNALLGEERFVVSDVPGTTRDAIDSLVAH
KGRRFVVTDTAGIRRKRSIAQKVESFSVVRAMKAMDQAEVVACLLDATEAGVEQDARLLGLVAEKGKALVIVVNKWDIAE
REGATQDWYRKELTKRLPFVGFAPMLFVSAKERRGVHRVLEKAARLVEQYRARFPTPQLNELLEALQDEHPAPIARGRRV
KLYYVAQVAYAPPTFVIQANHPDGLTDHYRRYIENRFRAAFGLEVPMRLVFKERQHRARPRRPRE

Sequences:

>Translated_465_residues
MTAPRPVVALVGRPNVGKSTLFNRLAGRRVAIVEDVPGVTRDRNYADVIWEGRAVSVVDTGGFEPESRDRLMSQVREQAQ
LAVDEASAVVLVVDGRDGLTALDRNVADLLRRAGKPLFVAVNKVDTARTEEDVPLAEFYGLGFGEVHAVSAEHGRGVSGL
VDAIVEKLALPPLPPAPEEADEPQEVSEAERPVGDIRLAIVGRPNVGKSTFVNALLGEERFVVSDVPGTTRDAIDSLVAH
KGRRFVVTDTAGIRRKRSIAQKVESFSVVRAMKAMDQAEVVACLLDATEAGVEQDARLLGLVAEKGKALVIVVNKWDIAE
REGATQDWYRKELTKRLPFVGFAPMLFVSAKERRGVHRVLEKAARLVEQYRARFPTPQLNELLEALQDEHPAPIARGRRV
KLYYVAQVAYAPPTFVIQANHPDGLTDHYRRYIENRFRAAFGLEVPMRLVFKERQHRARPRRPRE
>Mature_464_residues
TAPRPVVALVGRPNVGKSTLFNRLAGRRVAIVEDVPGVTRDRNYADVIWEGRAVSVVDTGGFEPESRDRLMSQVREQAQL
AVDEASAVVLVVDGRDGLTALDRNVADLLRRAGKPLFVAVNKVDTARTEEDVPLAEFYGLGFGEVHAVSAEHGRGVSGLV
DAIVEKLALPPLPPAPEEADEPQEVSEAERPVGDIRLAIVGRPNVGKSTFVNALLGEERFVVSDVPGTTRDAIDSLVAHK
GRRFVVTDTAGIRRKRSIAQKVESFSVVRAMKAMDQAEVVACLLDATEAGVEQDARLLGLVAEKGKALVIVVNKWDIAER
EGATQDWYRKELTKRLPFVGFAPMLFVSAKERRGVHRVLEKAARLVEQYRARFPTPQLNELLEALQDEHPAPIARGRRVK
LYYVAQVAYAPPTFVIQANHPDGLTDHYRRYIENRFRAAFGLEVPMRLVFKERQHRARPRRPRE

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=469, Percent_Identity=41.7910447761194, Blast_Score=329, Evalue=2e-91,
Organism=Escherichia coli, GI1788919, Length=164, Percent_Identity=34.1463414634146, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI2367268, Length=215, Percent_Identity=29.3023255813954, Blast_Score=70, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17507259, Length=134, Percent_Identity=30.5970149253731, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323665, Length=181, Percent_Identity=34.2541436464088, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 51553; Mature: 51421

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPRPVVALVGRPNVGKSTLFNRLAGRRVAIVEDVPGVTRDRNYADVIWEGRAVSVVDT
CCCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCHHEEECCCEEEEEEC
GGFEPESRDRLMSQVREQAQLAVDEASAVVLVVDGRDGLTALDRNVADLLRRAGKPLFVA
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEE
VNKVDTARTEEDVPLAEFYGLGFGEVHAVSAEHGRGVSGLVDAIVEKLALPPLPPAPEEA
EECCCCCCCCCCCCHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DEPQEVSEAERPVGDIRLAIVGRPNVGKSTFVNALLGEERFVVSDVPGTTRDAIDSLVAH
CCCHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHC
KGRRFVVTDTAGIRRKRSIAQKVESFSVVRAMKAMDQAEVVACLLDATEAGVEQDARLLG
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LVAEKGKALVIVVNKWDIAEREGATQDWYRKELTKRLPFVGFAPMLFVSAKERRGVHRVL
HHHCCCCEEEEEEECCCCHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCHHHCCHHHHH
EKAARLVEQYRARFPTPQLNELLEALQDEHPAPIARGRRVKLYYVAQVAYAPPTFVIQAN
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCEEEEECC
HPDGLTDHYRRYIENRFRAAFGLEVPMRLVFKERQHRARPRRPRE
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TAPRPVVALVGRPNVGKSTLFNRLAGRRVAIVEDVPGVTRDRNYADVIWEGRAVSVVDT
CCCCCEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCHHEEECCCEEEEEEC
GGFEPESRDRLMSQVREQAQLAVDEASAVVLVVDGRDGLTALDRNVADLLRRAGKPLFVA
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEE
VNKVDTARTEEDVPLAEFYGLGFGEVHAVSAEHGRGVSGLVDAIVEKLALPPLPPAPEEA
EECCCCCCCCCCCCHHHHHCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
DEPQEVSEAERPVGDIRLAIVGRPNVGKSTFVNALLGEERFVVSDVPGTTRDAIDSLVAH
CCCHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHC
KGRRFVVTDTAGIRRKRSIAQKVESFSVVRAMKAMDQAEVVACLLDATEAGVEQDARLLG
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHH
LVAEKGKALVIVVNKWDIAEREGATQDWYRKELTKRLPFVGFAPMLFVSAKERRGVHRVL
HHHCCCCEEEEEEECCCCHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHCCHHHCCHHHHH
EKAARLVEQYRARFPTPQLNELLEALQDEHPAPIARGRRVKLYYVAQVAYAPPTFVIQAN
HHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEEEECCCCEEEEECC
HPDGLTDHYRRYIENRFRAAFGLEVPMRLVFKERQHRARPRRPRE
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA