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The map label for this gene is era [H]

Identifier: 220917393

GI number: 220917393

Start: 2542753

End: 2543685

Strand: Reverse

Name: era [H]

Synonym: A2cp1_2293

Alternate gene names: 220917393

Gene position: 2543685-2542753 (Counterclockwise)

Preceding gene: 220917394

Following gene: 220917392

Centisome position: 50.58

GC content: 72.13

Gene sequence:

>933_bases
ATGGCCAGCAAGAAGAAGACCCCGTTCCGCGCCGGCTTCGTCGCCATCGTCGGCCGGCCGAACGTGGGGAAGTCCACGCT
GCTGAACCGCGTGCTCGGCGAGCACGTGGCCATCGTCAGCCCCCGCCCGCAGACCACCCGCACCCGCATCCTGGGCGTCC
ACAACGTCCCGGGCGCGCAGGTGGCGTTCTTCGACACCCCCGGCCTGCACAAGGCCAAGGGCGCGCTCAACCGGCGCATG
GTCGAGACCGCGCTGTCCACGCTGTCGGAGGTGGACGCGGTGCTCATGCTCATCGAGGCCGGCACCGGCCCCGAGGGTCG
CGTCGAGGTGGGCGAGTCCACCCGCTGGGCGATCGACGAGGTCCGGCGCGCGCGGAAGCCGGCGGTGCTGGGCGTCAACA
AGATGGACCGCGCGCCCCGCGCCACGCTGCTGCCGGTCATCGACGCCTACCGCGGGCTGCACGACTGGGCCGACATCGTC
CCGTTCTCGGCGCTCACGGGCGAGAACGTGGACACCCTGGTGCAGGCGCTCATCCGGCGGCTGCCCGAGTCCGAGGCCCC
GCTGTTCCCGGCCGACGTGCTCACCGACCAGGCGGAGCGCGCGCTGGCGGCGGAGTACGTGCGCGAGCAGGTGATGCTGC
AGACGCGCCAGGAGATCCCGTACGCGGCCGCGGTCGAGGTGGAGGAGTTCGACGAGTCCGGCCGGCGCGAGCGCGGCGGG
CTGGTCCGCATCTCGGCGCTCGTGGTGGTCGAGCGCGACTCGCAGAAGGCGATCGTGATCGGCAAGCAGGGCGCGATGCT
GAAGAAGATCGGCACGCGCGCGCGCGAGGGGCTGGAGCGGCTGCTCGGGTGCAAGGTGTTCCTGTCGCTGACCGTGAAGG
TGGACGAGCGCTGGAGCGAGCGCGAGGGCGCGCTGAAGAGGTTCGGGCTGTGA

Upstream 100 bases:

>100_bases
ACCCGCGGCGCGCAGCCCTAGCGCGCGCCGCCGCACGAAGGAACCCGGGCGCCCGCGCCCCCTCCGCCTCGAGCGGACGG
GCGCGGGCGCGATCACCTCC

Downstream 100 bases:

>100_bases
CGGCCCCCCGCCCCGTGGTGGCGCTGGTGGGCCGCCCGAACGTCGGGAAGTCCACGCTGTTCAACCGGCTGGCCGGCCGG
CGCGTCGCGATCGTGGAGGA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 309

Protein sequence:

>310_residues
MASKKKTPFRAGFVAIVGRPNVGKSTLLNRVLGEHVAIVSPRPQTTRTRILGVHNVPGAQVAFFDTPGLHKAKGALNRRM
VETALSTLSEVDAVLMLIEAGTGPEGRVEVGESTRWAIDEVRRARKPAVLGVNKMDRAPRATLLPVIDAYRGLHDWADIV
PFSALTGENVDTLVQALIRRLPESEAPLFPADVLTDQAERALAAEYVREQVMLQTRQEIPYAAAVEVEEFDESGRRERGG
LVRISALVVVERDSQKAIVIGKQGAMLKKIGTRAREGLERLLGCKVFLSLTVKVDERWSEREGALKRFGL

Sequences:

>Translated_310_residues
MASKKKTPFRAGFVAIVGRPNVGKSTLLNRVLGEHVAIVSPRPQTTRTRILGVHNVPGAQVAFFDTPGLHKAKGALNRRM
VETALSTLSEVDAVLMLIEAGTGPEGRVEVGESTRWAIDEVRRARKPAVLGVNKMDRAPRATLLPVIDAYRGLHDWADIV
PFSALTGENVDTLVQALIRRLPESEAPLFPADVLTDQAERALAAEYVREQVMLQTRQEIPYAAAVEVEEFDESGRRERGG
LVRISALVVVERDSQKAIVIGKQGAMLKKIGTRAREGLERLLGCKVFLSLTVKVDERWSEREGALKRFGL
>Mature_309_residues
ASKKKTPFRAGFVAIVGRPNVGKSTLLNRVLGEHVAIVSPRPQTTRTRILGVHNVPGAQVAFFDTPGLHKAKGALNRRMV
ETALSTLSEVDAVLMLIEAGTGPEGRVEVGESTRWAIDEVRRARKPAVLGVNKMDRAPRATLLPVIDAYRGLHDWADIVP
FSALTGENVDTLVQALIRRLPESEAPLFPADVLTDQAERALAAEYVREQVMLQTRQEIPYAAAVEVEEFDESGRRERGGL
VRISALVVVERDSQKAIVIGKQGAMLKKIGTRAREGLERLLGCKVFLSLTVKVDERWSEREGALKRFGL

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=307, Percent_Identity=41.042345276873, Blast_Score=221, Evalue=6e-59,
Organism=Escherichia coli, GI87082120, Length=178, Percent_Identity=33.1460674157303, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34055; Mature: 33924

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKKKTPFRAGFVAIVGRPNVGKSTLLNRVLGEHVAIVSPRPQTTRTRILGVHNVPGAQ
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEEEEECCCCCE
VAFFDTPGLHKAKGALNRRMVETALSTLSEVDAVLMLIEAGTGPEGRVEVGESTRWAIDE
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEECCCCHHHHHH
VRRARKPAVLGVNKMDRAPRATLLPVIDAYRGLHDWADIVPFSALTGENVDTLVQALIRR
HHHHCCCCEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHH
LPESEAPLFPADVLTDQAERALAAEYVREQVMLQTRQEIPYAAAVEVEEFDESGRRERGG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCHHCCC
LVRISALVVVERDSQKAIVIGKQGAMLKKIGTRAREGLERLLGCKVFLSLTVKVDERWSE
EEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEHHHHHH
REGALKRFGL
HHHHHHHCCC
>Mature Secondary Structure 
ASKKKTPFRAGFVAIVGRPNVGKSTLLNRVLGEHVAIVSPRPQTTRTRILGVHNVPGAQ
CCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCEEEECCCCCCCCEEEEEEECCCCCE
VAFFDTPGLHKAKGALNRRMVETALSTLSEVDAVLMLIEAGTGPEGRVEVGESTRWAIDE
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCEEECCCCHHHHHH
VRRARKPAVLGVNKMDRAPRATLLPVIDAYRGLHDWADIVPFSALTGENVDTLVQALIRR
HHHHCCCCEECCHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHH
LPESEAPLFPADVLTDQAERALAAEYVREQVMLQTRQEIPYAAAVEVEEFDESGRRERGG
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHCCCHHCCC
LVRISALVVVERDSQKAIVIGKQGAMLKKIGTRAREGLERLLGCKVFLSLTVKVDERWSE
EEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEHHHHHH
REGALKRFGL
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA