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The map label for this gene is hmp [H]

Identifier: 220915546

GI number: 220915546

Start: 481932

End: 482909

Strand: Direct

Name: hmp [H]

Synonym: A2cp1_0427

Alternate gene names: 220915546

Gene position: 481932-482909 (Clockwise)

Preceding gene: 220915545

Following gene: 220915547

Centisome position: 9.58

GC content: 74.03

Gene sequence:

>978_bases
ATGGCGGGCCGCCGCAGCCCCGCCTATGTCCTTTCGATGAGCGAGCCTGCCCTCGAGACCCGCGCCATCCGCACCGCCGT
CCCGCCGGAGGGCGAGCCGGTCCGCGCCGAGGTCCCGCGGCGGCGCATCAAGGACCTCGAGGTGATGGTCGCCGACGTCA
TCCAGGAGACGCCGGACACCACCACGCTCGTGCTCTTCACCGGCAACGATCGGCTCGACTACCTGGCCGGCCACTTCCTG
ACCATCGACCCGCGCCAGTTCCCGGCGCTCGAGCGATGGGTGGCCTACCTCGAGGACCTCAAGGGGAAGCGCGAGGCGCC
GCGCGCCTACTCGCTGGCGTCCGCGCCGCACGAGCGCTACCTCGCCATCACGGTGAAGGAGGAGACGTACCAGAGCGGGC
GCACGCGGTACCCGCCGCTCCTCTCGCCGATGCTGGTGCGGCGCACGCCGCGCGGCAGCCGCTTCGTCATCACCGGCTTC
ACCGGGCCCTACGTGCTGCCTCCGCGCGTGGAGGAGAAGACCGACCACCTCGTGCACGTGGTGGCCGGCTCCGGCTCGGT
GCCGAACTGGTCGATCCTGAAGCACGCGCTCCGCGAGCACCCGCGCCTGCGCCACACGTTCGTCTACTCGAACCGGACCT
GGGACGACGTCATCTACCGCGACGGCCTGCGCCAGCTCGAGGCCGAGCACCCCGACCGGCTGCGGGTGGTGCACACGCTC
ACCCGCGAGCCGGAGCCGGAGCGCCACGGGCCCGGCGTGCGGCGCGGCCGCATCTCGGCGGAGCTCCTCCGCGAGCTCGT
CCCGGATCCGCGCGCCGCGCTCTGGTACGCCTGCGGCCCCGCGGTCGGGCCCATCGAGCGCGCCGCCGCGAAGGAGCGCG
GCGAGACCCCCGCCCCCCGGTTCCTGGAGGCCGCGCTCGCCGCGCTGGACGAGCTCGGCGTGCCGCGCGACCGGGTGAAG
CGCGAGTCGTACGGGTAG

Upstream 100 bases:

>100_bases
GCGCTGCTCGCGGCTCGACCGCCTGGCTCGGTCCGGGGATGGATTCACGCGCTCTGAGCCCGGCTCGCCTCCCTCCGTCG
CCGGCAGACTCGATCGCGGC

Downstream 100 bases:

>100_bases
CGCCCCGCGCCATTCCGTGGCGCCCGCGCGCGCGACGATCTACCTTTCCGCCCGCCCGTGCCCCGGACCCTGCGCGCCAT
CCCCACGCTCCTCAAGGTCG

Product: oxidoreductase FAD/NAD(P)-binding domain-containing protein

Products: NA

Alternate protein names: Rieske-type oxygenase; RO [H]

Number of amino acids: Translated: 325; Mature: 324

Protein sequence:

>325_residues
MAGRRSPAYVLSMSEPALETRAIRTAVPPEGEPVRAEVPRRRIKDLEVMVADVIQETPDTTTLVLFTGNDRLDYLAGHFL
TIDPRQFPALERWVAYLEDLKGKREAPRAYSLASAPHERYLAITVKEETYQSGRTRYPPLLSPMLVRRTPRGSRFVITGF
TGPYVLPPRVEEKTDHLVHVVAGSGSVPNWSILKHALREHPRLRHTFVYSNRTWDDVIYRDGLRQLEAEHPDRLRVVHTL
TREPEPERHGPGVRRGRISAELLRELVPDPRAALWYACGPAVGPIERAAAKERGETPAPRFLEAALAALDELGVPRDRVK
RESYG

Sequences:

>Translated_325_residues
MAGRRSPAYVLSMSEPALETRAIRTAVPPEGEPVRAEVPRRRIKDLEVMVADVIQETPDTTTLVLFTGNDRLDYLAGHFL
TIDPRQFPALERWVAYLEDLKGKREAPRAYSLASAPHERYLAITVKEETYQSGRTRYPPLLSPMLVRRTPRGSRFVITGF
TGPYVLPPRVEEKTDHLVHVVAGSGSVPNWSILKHALREHPRLRHTFVYSNRTWDDVIYRDGLRQLEAEHPDRLRVVHTL
TREPEPERHGPGVRRGRISAELLRELVPDPRAALWYACGPAVGPIERAAAKERGETPAPRFLEAALAALDELGVPRDRVK
RESYG
>Mature_324_residues
AGRRSPAYVLSMSEPALETRAIRTAVPPEGEPVRAEVPRRRIKDLEVMVADVIQETPDTTTLVLFTGNDRLDYLAGHFLT
IDPRQFPALERWVAYLEDLKGKREAPRAYSLASAPHERYLAITVKEETYQSGRTRYPPLLSPMLVRRTPRGSRFVITGFT
GPYVLPPRVEEKTDHLVHVVAGSGSVPNWSILKHALREHPRLRHTFVYSNRTWDDVIYRDGLRQLEAEHPDRLRVVHTLT
REPEPERHGPGVRRGRISAELLRELVPDPRAALWYACGPAVGPIERAAAKERGETPAPRFLEAALAALDELGVPRDRVKR
ESYG

Specific function: Catalyzes the opening of ring B of 1,4-androstadiene- 3,17,-dione (ADD) and 4-androstene-3,17-dione (ADD) with concomitant aromatization of ring A. The ring B is subsequently hydroxylated to yield a catechol and then subject to meta- cleavage [H]

COG id: COG1018

COG function: function code C; Flavodoxin reductases (ferredoxin-NADPH reductases) family 1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR017927
- InterPro:   IPR001041
- InterPro:   IPR001709
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR001221
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00970 FAD_binding_6; PF00111 Fer2; PF00175 NAD_binding_1 [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36801; Mature: 36669

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGRRSPAYVLSMSEPALETRAIRTAVPPEGEPVRAEVPRRRIKDLEVMVADVIQETPDT
CCCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
TTLVLFTGNDRLDYLAGHFLTIDPRQFPALERWVAYLEDLKGKREAPRAYSLASAPHERY
EEEEEEECCCCHHHHCCCEEEECCHHCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCE
LAITVKEETYQSGRTRYPPLLSPMLVRRTPRGSRFVITGFTGPYVLPPRVEEKTDHLVHV
EEEEEEHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCEECCCCCCCCCCEEEEE
VAGSGSVPNWSILKHALREHPRLRHTFVYSNRTWDDVIYRDGLRQLEAEHPDRLRVVHTL
EECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
TREPEPERHGPGVRRGRISAELLRELVPDPRAALWYACGPAVGPIERAAAKERGETPAPR
HCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHH
FLEAALAALDELGVPRDRVKRESYG
HHHHHHHHHHHCCCCHHHHHHCCCC
>Mature Secondary Structure 
AGRRSPAYVLSMSEPALETRAIRTAVPPEGEPVRAEVPRRRIKDLEVMVADVIQETPDT
CCCCCCCEEEECCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
TTLVLFTGNDRLDYLAGHFLTIDPRQFPALERWVAYLEDLKGKREAPRAYSLASAPHERY
EEEEEEECCCCHHHHCCCEEEECCHHCHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCCCE
LAITVKEETYQSGRTRYPPLLSPMLVRRTPRGSRFVITGFTGPYVLPPRVEEKTDHLVHV
EEEEEEHHHHHCCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCEECCCCCCCCCCEEEEE
VAGSGSVPNWSILKHALREHPRLRHTFVYSNRTWDDVIYRDGLRQLEAEHPDRLRVVHTL
EECCCCCCCHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCHHHHHHHHH
TREPEPERHGPGVRRGRISAELLRELVPDPRAALWYACGPAVGPIERAAAKERGETPAPR
HCCCCCCCCCCCCHHCCHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHCCCCCCHH
FLEAALAALDELGVPRDRVKRESYG
HHHHHHHHHHHCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD [C]

Metal ions: Iron-Sulfur [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]