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The map label for this gene is yhcK [H]

Identifier: 220915271

GI number: 220915271

Start: 168139

End: 169008

Strand: Direct

Name: yhcK [H]

Synonym: A2cp1_0150

Alternate gene names: 220915271

Gene position: 168139-169008 (Clockwise)

Preceding gene: 220915270

Following gene: 220915272

Centisome position: 3.34

GC content: 78.97

Gene sequence:

>870_bases
ATGGGCGACGACCCCACCCGCGTCCGGACCCCGGAGGAGCGCGCCGCCGCCGCGGCCGGCCACTGCCTCGTGTTCGTGGC
GGGGGACGGCGCGCTCGGCCTGCGGGTGCCGCTCGACGGCGAGGTGGTGCTCGGGCGCGATCCGTCCTGCGCGGTGGCGC
TGCCCGCCTCCGACGTCTCGCGCCGGCACGCCCGCGTGGTGCCGGACGGCGACGGCCACCTGGTGCTCGACCTCGGCTCC
ACCAACGGCACCTGGGTGAACGGCCGCGAGGTGGCGGTGCACCGGCTCGCCCCGGGCGACCGGGTGCAGGTGGGCGCGTT
CGTGGCGCGCTACCTGCGGGCCGGCGACGCGGAGGAGTCGGAGCTCGCCGCGCTGGCCGACCTGGCGCTGCGCGATCCGC
TCACCGGCCTCCCCAACCGCCGCGCCTTCGAGGAGTCGCTCCGCCGCGAGGTGGCGCGGGCGCGGCGCGGCGGCGACCGG
CTGGCGGTGGCGGTGCTCGACGTGGATCGCTTCAAGGACGTGAACGACCGGCACGGCCACGCGGCGGGCGACGTCGCGCT
CGCCGAGGTGGCGCGCCGGGCATCGGCGGCGCTGCGGGCCGGGGATCTCCTGGCGCGCATCGGCGGCGAGGAGCTCGCCG
CCATCCTGCCCGGCGCCGACGTGGCGGCCGCCGCCGAGGTGGCCGAGCGCGTCCGTCGCGCGGTGGGCACGGAGCCGGTG
CAGGCGGGCGGGCAGGCGATCCGCGTGACCGTCTCGCTCGGCTGCGCCGAGCTCGCGCCCGACGACGCCGACGGCGCCGA
CCTGTTCGCACGGGCCGACGGCCACCTGTACCGCGCCAAGCACGCCGGCCGCGATCGCGTGGAGTTCTGA

Upstream 100 bases:

>100_bases
TCGCGCTCACCGTGCCCGACCAGGACTTCGAGCGCATCCACTGGCGGGTGTAGCGCATCGCGCGCCCGGCGCGCGGGGCC
CGGTGTAGACTCGCGGTCGC

Downstream 100 bases:

>100_bases
TCGGCCGGCGGCGGCGCCCGGGTGCGCCGCCCCGCGATCCCCCGCCCTCACCCGAACGCGCCCGGCGGCGCGCGCCCGGC
CCGGCAGGAAAGCCTGCGCC

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MGDDPTRVRTPEERAAAAAGHCLVFVAGDGALGLRVPLDGEVVLGRDPSCAVALPASDVSRRHARVVPDGDGHLVLDLGS
TNGTWVNGREVAVHRLAPGDRVQVGAFVARYLRAGDAEESELAALADLALRDPLTGLPNRRAFEESLRREVARARRGGDR
LAVAVLDVDRFKDVNDRHGHAAGDVALAEVARRASAALRAGDLLARIGGEELAAILPGADVAAAAEVAERVRRAVGTEPV
QAGGQAIRVTVSLGCAELAPDDADGADLFARADGHLYRAKHAGRDRVEF

Sequences:

>Translated_289_residues
MGDDPTRVRTPEERAAAAAGHCLVFVAGDGALGLRVPLDGEVVLGRDPSCAVALPASDVSRRHARVVPDGDGHLVLDLGS
TNGTWVNGREVAVHRLAPGDRVQVGAFVARYLRAGDAEESELAALADLALRDPLTGLPNRRAFEESLRREVARARRGGDR
LAVAVLDVDRFKDVNDRHGHAAGDVALAEVARRASAALRAGDLLARIGGEELAAILPGADVAAAAEVAERVRRAVGTEPV
QAGGQAIRVTVSLGCAELAPDDADGADLFARADGHLYRAKHAGRDRVEF
>Mature_288_residues
GDDPTRVRTPEERAAAAAGHCLVFVAGDGALGLRVPLDGEVVLGRDPSCAVALPASDVSRRHARVVPDGDGHLVLDLGST
NGTWVNGREVAVHRLAPGDRVQVGAFVARYLRAGDAEESELAALADLALRDPLTGLPNRRAFEESLRREVARARRGGDRL
AVAVLDVDRFKDVNDRHGHAAGDVALAEVARRASAALRAGDLLARIGGEELAAILPGADVAAAAEVAERVRRAVGTEPVQ
AGGQAIRVTVSLGCAELAPDDADGADLFARADGHLYRAKHAGRDRVEF

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI87082007, Length=167, Percent_Identity=41.9161676646707, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788381, Length=185, Percent_Identity=36.7567567567568, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=36.046511627907, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1786584, Length=164, Percent_Identity=34.7560975609756, Blast_Score=104, Evalue=9e-24,
Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=38.6075949367089, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI87081881, Length=206, Percent_Identity=34.4660194174757, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI87081977, Length=217, Percent_Identity=29.9539170506912, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787802, Length=172, Percent_Identity=32.5581395348837, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1787816, Length=158, Percent_Identity=33.5443037974684, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788085, Length=200, Percent_Identity=27.5, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787541, Length=158, Percent_Identity=32.2784810126582, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788956, Length=179, Percent_Identity=34.6368715083799, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87081974, Length=158, Percent_Identity=27.2151898734177, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 30257; Mature: 30126

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: PS50006 FHA_DOMAIN ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.3 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDDPTRVRTPEERAAAAAGHCLVFVAGDGALGLRVPLDGEVVLGRDPSCAVALPASDVS
CCCCCCCCCCCHHHHHHCCCCEEEEEECCCCEEEEECCCCCEEECCCCCCEEEECCHHHH
RRHARVVPDGDGHLVLDLGSTNGTWVNGREVAVHRLAPGDRVQVGAFVARYLRAGDAEES
HHCCEECCCCCCEEEEEECCCCCCEECCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCHH
ELAALADLALRDPLTGLPNRRAFEESLRREVARARRGGDRLAVAVLDVDRFKDVNDRHGH
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHCCCCCCCCC
AAGDVALAEVARRASAALRAGDLLARIGGEELAAILPGADVAAAAEVAERVRRAVGTEPV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCH
QAGGQAIRVTVSLGCAELAPDDADGADLFARADGHLYRAKHAGRDRVEF
HCCCEEEEEEEEECHHHCCCCCCCCCCEEEECCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
GDDPTRVRTPEERAAAAAGHCLVFVAGDGALGLRVPLDGEVVLGRDPSCAVALPASDVS
CCCCCCCCCCHHHHHHCCCCEEEEEECCCCEEEEECCCCCEEECCCCCCEEEECCHHHH
RRHARVVPDGDGHLVLDLGSTNGTWVNGREVAVHRLAPGDRVQVGAFVARYLRAGDAEES
HHCCEECCCCCCEEEEEECCCCCCEECCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCHH
ELAALADLALRDPLTGLPNRRAFEESLRREVARARRGGDRLAVAVLDVDRFKDVNDRHGH
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEHHHHCCCCCCCCC
AAGDVALAEVARRASAALRAGDLLARIGGEELAAILPGADVAAAAEVAERVRRAVGTEPV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCH
QAGGQAIRVTVSLGCAELAPDDADGADLFARADGHLYRAKHAGRDRVEF
HCCCEEEEEEEEECHHHCCCCCCCCCCEEEECCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8969498; 9384377 [H]