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The map label for this gene is add [H]

Identifier: 220915237

GI number: 220915237

Start: 130845

End: 131975

Strand: Direct

Name: add [H]

Synonym: A2cp1_0116

Alternate gene names: 220915237

Gene position: 130845-131975 (Clockwise)

Preceding gene: 220915236

Following gene: 220915238

Centisome position: 2.6

GC content: 71.53

Gene sequence:

>1131_bases
ATGGCCCAGGCCGCCGCGACGACGCTCCCGCAGGTGACGGAGGCGCTCGTCCGCGACCTCCCCAAGACCGACCTGCACTG
CCACCTCGACGGCTCGGTCCGGCTCGCCACCGTGCTGGACCTCGCCGCGCAGCAGGGGGTGCGCCTGCCCGCCGAGACGC
CCGAGGGGCTCGCGAAGGCCATCCACATGGGCGAGGTGTGCGCCTCGCTGGAGGACTACCTCACCGCGTTCGACGTCACG
CTCGCGGTGCTCCAGACCGAGGAGGCGCTGTACCGGACCGCCTACGAGCTCGCGCTCGACGCGGCCGCCGAGAACGTCCG
CTACCTCGAGGTCCGCTACTCGCCGGTCCTGCACACCAGGAAGGGCCTGAAGCCCACCTCCATCGTGGACGCGGTGCTGG
CCGGGCTGCGGGCGGCGCGGCGCGAGACCGGGATCGAGTCGAACGTCATCATCTGCGGGATCCGCCACATCGATCCCATG
ACCTCGGTGCGCCTCGCCGAGCTGGCGGTCGCGTACAAGGGCAAGGGCGTGGTGGGGTTCGACCTCGCCGGCGCGGAGGA
GGGCCACCCGGCGCGGCGTCACCGCGACGCGGTCCAGCTCATCCTCGACAACAACGTGAACGTGACCATCCACGCCGGGG
AGGCGTTCGGACCGGAGTCCATCGCGCAGGCGGTGCACTGGTGCGGCGCCCACCGCATCGGCCACGGCGTGCGGCTGCGC
GAGAACGGCGACCTGCTCAACTACCTGAACGACCACCGCATCCCGCTGGAGATGTGCCCGTCGTCGAACGTCCAGACCGG
CTCGGTGCAGGGCTTCGCGAGCCACCCGCTCAAGTTCTACTTCGACTTCGGCCTGCGGGTCTCGGTGAACACCGACAACC
GCCTCATCACCGACACCACCGTCACGAAGGAGCTGCTGGTGGCGCACCGCGAGATGGGCTTCACGCTGGAGGACCTCTGC
ACCGTGCTGGTGCAGGGCTTCAAGAGCGCGTTCCTGCCGTTCCGCGACAAGCAGGAGCTGCTCCGGCGGGTGAACCTGGA
GATCGCGCAGGTGCTCGCGCGCCACGGCGCGCCGGCGCCGGTCGCGGGCGACGGCGCGGCCCGCGCGGCGGTCGAGGCGG
GGACGCCGTGA

Upstream 100 bases:

>100_bases
CTAGCGCGCCTGCCCCGTTCGCCGGGCGCGGGCCCCACCTCGCCGGGCGGCGCCCCCACCCGCCCCTCCCTCCGAGGCGG
CGGCGGCGTATGATCCGGGC

Downstream 100 bases:

>100_bases
CCGCGCGCCTGCGCTACCGCTCGCCGGTGGGGATCCTCACGGTCGAGGCGAGCGACGAGGGGGTGTTCGGCCTTTCGTTC
GGCGATCGCGGGCCGTCGCG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 376; Mature: 375

Protein sequence:

>376_residues
MAQAAATTLPQVTEALVRDLPKTDLHCHLDGSVRLATVLDLAAQQGVRLPAETPEGLAKAIHMGEVCASLEDYLTAFDVT
LAVLQTEEALYRTAYELALDAAAENVRYLEVRYSPVLHTRKGLKPTSIVDAVLAGLRAARRETGIESNVIICGIRHIDPM
TSVRLAELAVAYKGKGVVGFDLAGAEEGHPARRHRDAVQLILDNNVNVTIHAGEAFGPESIAQAVHWCGAHRIGHGVRLR
ENGDLLNYLNDHRIPLEMCPSSNVQTGSVQGFASHPLKFYFDFGLRVSVNTDNRLITDTTVTKELLVAHREMGFTLEDLC
TVLVQGFKSAFLPFRDKQELLRRVNLEIAQVLARHGAPAPVAGDGAARAAVEAGTP

Sequences:

>Translated_376_residues
MAQAAATTLPQVTEALVRDLPKTDLHCHLDGSVRLATVLDLAAQQGVRLPAETPEGLAKAIHMGEVCASLEDYLTAFDVT
LAVLQTEEALYRTAYELALDAAAENVRYLEVRYSPVLHTRKGLKPTSIVDAVLAGLRAARRETGIESNVIICGIRHIDPM
TSVRLAELAVAYKGKGVVGFDLAGAEEGHPARRHRDAVQLILDNNVNVTIHAGEAFGPESIAQAVHWCGAHRIGHGVRLR
ENGDLLNYLNDHRIPLEMCPSSNVQTGSVQGFASHPLKFYFDFGLRVSVNTDNRLITDTTVTKELLVAHREMGFTLEDLC
TVLVQGFKSAFLPFRDKQELLRRVNLEIAQVLARHGAPAPVAGDGAARAAVEAGTP
>Mature_375_residues
AQAAATTLPQVTEALVRDLPKTDLHCHLDGSVRLATVLDLAAQQGVRLPAETPEGLAKAIHMGEVCASLEDYLTAFDVTL
AVLQTEEALYRTAYELALDAAAENVRYLEVRYSPVLHTRKGLKPTSIVDAVLAGLRAARRETGIESNVIICGIRHIDPMT
SVRLAELAVAYKGKGVVGFDLAGAEEGHPARRHRDAVQLILDNNVNVTIHAGEAFGPESIAQAVHWCGAHRIGHGVRLRE
NGDLLNYLNDHRIPLEMCPSSNVQTGSVQGFASHPLKFYFDFGLRVSVNTDNRLITDTTVTKELLVAHREMGFTLEDLCT
VLVQGFKSAFLPFRDKQELLRRVNLEIAQVLARHGAPAPVAGDGAARAAVEAGTP

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=340, Percent_Identity=34.7058823529412, Blast_Score=179, Evalue=3e-45,
Organism=Homo sapiens, GI61175224, Length=246, Percent_Identity=26.0162601626016, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1787910, Length=326, Percent_Identity=34.3558282208589, Blast_Score=187, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17538512, Length=352, Percent_Identity=32.6704545454545, Blast_Score=164, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI32565969, Length=337, Percent_Identity=33.2344213649852, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6324188, Length=285, Percent_Identity=25.6140350877193, Blast_Score=114, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24645260, Length=343, Percent_Identity=28.2798833819242, Blast_Score=102, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 40735; Mature: 40604

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAAATTLPQVTEALVRDLPKTDLHCHLDGSVRLATVLDLAAQQGVRLPAETPEGLAKA
CCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHH
IHMGEVCASLEDYLTAFDVTLAVLQTEEALYRTAYELALDAAAENVRYLEVRYSPVLHTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHH
KGLKPTSIVDAVLAGLRAARRETGIESNVIICGIRHIDPMTSVRLAELAVAYKGKGVVGF
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEE
DLAGAEEGHPARRHRDAVQLILDNNVNVTIHAGEAFGPESIAQAVHWCGAHRIGHGVRLR
ECCCCCCCCCHHHHHHHEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEE
ENGDLLNYLNDHRIPLEMCPSSNVQTGSVQGFASHPLKFYFDFGLRVSVNTDNRLITDTT
CCCCHHHHHCCCCCCCEECCCCCCCCCCCCCHHCCCEEEEEECCEEEEECCCCEEEECHH
VTKELLVAHREMGFTLEDLCTVLVQGFKSAFLPFRDKQELLRRVNLEIAQVLARHGAPAP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHCCCCCC
VAGDGAARAAVEAGTP
CCCCCHHHHCCCCCCC
>Mature Secondary Structure 
AQAAATTLPQVTEALVRDLPKTDLHCHLDGSVRLATVLDLAAQQGVRLPAETPEGLAKA
CCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHH
IHMGEVCASLEDYLTAFDVTLAVLQTEEALYRTAYELALDAAAENVRYLEVRYSPVLHTR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHH
KGLKPTSIVDAVLAGLRAARRETGIESNVIICGIRHIDPMTSVRLAELAVAYKGKGVVGF
CCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEE
DLAGAEEGHPARRHRDAVQLILDNNVNVTIHAGEAFGPESIAQAVHWCGAHRIGHGVRLR
ECCCCCCCCCHHHHHHHEEEEECCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEE
ENGDLLNYLNDHRIPLEMCPSSNVQTGSVQGFASHPLKFYFDFGLRVSVNTDNRLITDTT
CCCCHHHHHCCCCCCCEECCCCCCCCCCCCCHHCCCEEEEEECCEEEEECCCCEEEECHH
VTKELLVAHREMGFTLEDLCTVLVQGFKSAFLPFRDKQELLRRVNLEIAQVLARHGAPAP
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCHHHHHHHHHCCCCCC
VAGDGAARAAVEAGTP
CCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA