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The map label for this gene is htpG [H]

Identifier: 220905459

GI number: 220905459

Start: 2647648

End: 2649630

Strand: Direct

Name: htpG [H]

Synonym: Ddes_2197

Alternate gene names: 220905459

Gene position: 2647648-2649630 (Clockwise)

Preceding gene: 220905455

Following gene: 220905461

Centisome position: 92.14

GC content: 58.3

Gene sequence:

>1983_bases
ATGGCAGAGGCAGATAGGAATCCCCGCCAGTTTCGTGCAGAGGTGCGTAAGGTTTTACACATCCTTACCAACTCCCTCTA
TACCAACCGGGAAATTTTTTTGCGTGAGCTTATTTCCAACGCTTCGGACGCGCTGGACAAACTGCGTTTTCGCATCAACC
GCGGCGAAAGCCCCCGCTTGCCCGATCTGCCGCTGGAAATTCGCATCTCACTCGACAAAGAGGCGAAAACCATCACCATT
GCCGATACCGGTCTGGGCATGACCGCCGATGAACTGGCGGAGCACCTGGGTACCATAGCCAAATCCGGTTCAGAGCAGTT
TTTGGCCGACATCGCGGCCGAAAAGGCTGCCAAGGCAACATCCGCCAGCGGCAAGGACGATACCGCAGACGAAGAGCAAA
ACGCCGGGGCCGAGGCTGATGCCACCAATATCATCGGGCGCTTCGGCGTGGGTTTTTACTCGGTCTTTATGGTGGCTGAA
AAAGTAACTGTCACCTCGCGCCCGGCATTTGGCGAAGACAGCGCCGCCCACACCTGGACCAGCGATGGCCTTGGAACCTA
CACGGTCGCGCCGGCGGAAGGCGACGAGCCACAGCGTGGTACGGTTATCACTGCATGGCTCAAGGACGATGCCGTGGAGT
TTCTTGAAAAATTCCGCGTAGAGTCTGCCATCCGCAAGCACTCTGCCTTTGTGCCTTTTCCTGTCCTTGTGGACGGCGAG
CAGGTCAATACCCAGCCCGCCCTGTGGCGTGAGCCCAAGTTTTCCGTCACGCAGGAGCAGTACGCGGCCTTTTACAAGGC
TCTTACCTATGACAGCAAAGACCCGCTGGATGTGCTGCATTTTTCCGTTGACGCTCCCGTGCAGTTCAACGCCCTCTTTT
TCATTCCCGACAACGCCCAGGATTTCTTCGGCGCAGACCGCGACTTCTGGGGGCTGGATCTCTACGCCCGCCGCGTGCTG
ATCCAGCACCGCAACAAAGAACTGATCCCCGAGTACCTGGCATTCCTCAAGGGCGTGGTCGACACCGAAGACCTGCCCCT
GAACATCTCGCGCGAAACACTGCAGGAAAACGTGGTTCTGCGCAAGATCAACCAGGTCATCATCAAGCAGACCCTCGGCC
ATCTTGAAAAGCTGGCAAAAAATGATGCGGAAAAATATGCGGCCTTCTGGCGTCTGCACGGGAAGGTTTTCAAGCTCGGC
TATCACGATTTTGCCAACCGCGAGAGGGTCACTGCCCTGCTGCGCTTCAATTCTTCCACCCTGGCCGACGCCGAAGCCCT
GACCAGCCTGGACGAATACATGGACCGCGCGCCCGAAGGCCAAAAAACCTTCTGGTATGTGGCCGCGCCCAACCGTGAGG
CAGCGCGCCTGAACCCGCATATGGAGCGCTTTCGCCAAAAGGGCATAGAGGTTCTCTATCTTTTTGAACCCATTGACGAA
TTCGTCATGGACGGCCTTGGCCGTTACAAGGAATGGGACTTCAGGTCTGTGGAAACCGCGGCTGATGACGCCCTCAAGGA
CTTCAGCGACAAGGAAAGCCCGACCCGCGAGGCCGCCGCACCCCTTTCGGACGAAGATAGCGCCAGCTTTGACGGCCTGC
TGACCCGCATGAAGGAAGTGCTGGGCGACAAGGTAACGGAAGTGCGCGTTTCGCACCGCCTGGCCGACAGCCCCGCCGTG
CTTGTCTCGCCTGACGGCGGCCTTTCCTCGTCTATGGAAAAGCTGCTCAAGGTCATGCAGAAGGACGATTCCCTCCCGGT
AAAAGTGCTGGAGGTCAACCGCGACCACCCCCTGCTGCGCAACATGCTGCGCATGTTCAAGGCCGACAGCAGCGACAGGA
TCCTGGCCGAGATGACCCAGAGCCTTTTTGATGCCAGCCTGCTGCTGGACGGCTACCTCAAAGACCCGCAGGCCCTGGCC
GCCCGCACCGGCAAACTGCTGGAAGAAGCCGCAGCCTGGTATACAGAGGTGCGCAAAATATAA

Upstream 100 bases:

>100_bases
CCTCCGAAGCTACAATTTTTTCACCTCGCAGCCATCACGCCCCTTGAAAAATCAAAAAGCGGTATTATCTGCAAGGATAT
CGCTTTTCAGGAGGTTTGTC

Downstream 100 bases:

>100_bases
GGGCGCGGGGAATGGCTGCTTTTACAAAAGCTCCTCCTCCGCGCCCTGCTCTCAACACCCTTGGCATGGATCAAAGCCGT
CGCCCGGGCTGCCTGAAAGA

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 660; Mature: 659

Protein sequence:

>660_residues
MAEADRNPRQFRAEVRKVLHILTNSLYTNREIFLRELISNASDALDKLRFRINRGESPRLPDLPLEIRISLDKEAKTITI
ADTGLGMTADELAEHLGTIAKSGSEQFLADIAAEKAAKATSASGKDDTADEEQNAGAEADATNIIGRFGVGFYSVFMVAE
KVTVTSRPAFGEDSAAHTWTSDGLGTYTVAPAEGDEPQRGTVITAWLKDDAVEFLEKFRVESAIRKHSAFVPFPVLVDGE
QVNTQPALWREPKFSVTQEQYAAFYKALTYDSKDPLDVLHFSVDAPVQFNALFFIPDNAQDFFGADRDFWGLDLYARRVL
IQHRNKELIPEYLAFLKGVVDTEDLPLNISRETLQENVVLRKINQVIIKQTLGHLEKLAKNDAEKYAAFWRLHGKVFKLG
YHDFANRERVTALLRFNSSTLADAEALTSLDEYMDRAPEGQKTFWYVAAPNREAARLNPHMERFRQKGIEVLYLFEPIDE
FVMDGLGRYKEWDFRSVETAADDALKDFSDKESPTREAAAPLSDEDSASFDGLLTRMKEVLGDKVTEVRVSHRLADSPAV
LVSPDGGLSSSMEKLLKVMQKDDSLPVKVLEVNRDHPLLRNMLRMFKADSSDRILAEMTQSLFDASLLLDGYLKDPQALA
ARTGKLLEEAAAWYTEVRKI

Sequences:

>Translated_660_residues
MAEADRNPRQFRAEVRKVLHILTNSLYTNREIFLRELISNASDALDKLRFRINRGESPRLPDLPLEIRISLDKEAKTITI
ADTGLGMTADELAEHLGTIAKSGSEQFLADIAAEKAAKATSASGKDDTADEEQNAGAEADATNIIGRFGVGFYSVFMVAE
KVTVTSRPAFGEDSAAHTWTSDGLGTYTVAPAEGDEPQRGTVITAWLKDDAVEFLEKFRVESAIRKHSAFVPFPVLVDGE
QVNTQPALWREPKFSVTQEQYAAFYKALTYDSKDPLDVLHFSVDAPVQFNALFFIPDNAQDFFGADRDFWGLDLYARRVL
IQHRNKELIPEYLAFLKGVVDTEDLPLNISRETLQENVVLRKINQVIIKQTLGHLEKLAKNDAEKYAAFWRLHGKVFKLG
YHDFANRERVTALLRFNSSTLADAEALTSLDEYMDRAPEGQKTFWYVAAPNREAARLNPHMERFRQKGIEVLYLFEPIDE
FVMDGLGRYKEWDFRSVETAADDALKDFSDKESPTREAAAPLSDEDSASFDGLLTRMKEVLGDKVTEVRVSHRLADSPAV
LVSPDGGLSSSMEKLLKVMQKDDSLPVKVLEVNRDHPLLRNMLRMFKADSSDRILAEMTQSLFDASLLLDGYLKDPQALA
ARTGKLLEEAAAWYTEVRKI
>Mature_659_residues
AEADRNPRQFRAEVRKVLHILTNSLYTNREIFLRELISNASDALDKLRFRINRGESPRLPDLPLEIRISLDKEAKTITIA
DTGLGMTADELAEHLGTIAKSGSEQFLADIAAEKAAKATSASGKDDTADEEQNAGAEADATNIIGRFGVGFYSVFMVAEK
VTVTSRPAFGEDSAAHTWTSDGLGTYTVAPAEGDEPQRGTVITAWLKDDAVEFLEKFRVESAIRKHSAFVPFPVLVDGEQ
VNTQPALWREPKFSVTQEQYAAFYKALTYDSKDPLDVLHFSVDAPVQFNALFFIPDNAQDFFGADRDFWGLDLYARRVLI
QHRNKELIPEYLAFLKGVVDTEDLPLNISRETLQENVVLRKINQVIIKQTLGHLEKLAKNDAEKYAAFWRLHGKVFKLGY
HDFANRERVTALLRFNSSTLADAEALTSLDEYMDRAPEGQKTFWYVAAPNREAARLNPHMERFRQKGIEVLYLFEPIDEF
VMDGLGRYKEWDFRSVETAADDALKDFSDKESPTREAAAPLSDEDSASFDGLLTRMKEVLGDKVTEVRVSHRLADSPAVL
VSPDGGLSSSMEKLLKVMQKDDSLPVKVLEVNRDHPLLRNMLRMFKADSSDRILAEMTQSLFDASLLLDGYLKDPQALAA
RTGKLLEEAAAWYTEVRKI

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=705, Percent_Identity=35.0354609929078, Blast_Score=394, Evalue=1e-109,
Organism=Homo sapiens, GI155722983, Length=652, Percent_Identity=36.6564417177914, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI20149594, Length=421, Percent_Identity=37.5296912114014, Blast_Score=263, Evalue=5e-70,
Organism=Homo sapiens, GI154146191, Length=421, Percent_Identity=34.6793349168646, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI153792590, Length=421, Percent_Identity=34.6793349168646, Blast_Score=239, Evalue=5e-63,
Organism=Escherichia coli, GI1786679, Length=657, Percent_Identity=39.2694063926941, Blast_Score=424, Evalue=1e-120,
Organism=Caenorhabditis elegans, GI17559162, Length=695, Percent_Identity=32.9496402877698, Blast_Score=386, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI115535205, Length=659, Percent_Identity=37.4810318664643, Blast_Score=378, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI17542208, Length=698, Percent_Identity=32.5214899713467, Blast_Score=337, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI115535167, Length=437, Percent_Identity=40.7322654462243, Blast_Score=291, Evalue=6e-79,
Organism=Saccharomyces cerevisiae, GI6325016, Length=708, Percent_Identity=33.8983050847458, Blast_Score=379, Evalue=1e-106,
Organism=Saccharomyces cerevisiae, GI6323840, Length=703, Percent_Identity=33.8549075391181, Blast_Score=377, Evalue=1e-105,
Organism=Drosophila melanogaster, GI24586016, Length=661, Percent_Identity=35.8547655068079, Blast_Score=374, Evalue=1e-103,
Organism=Drosophila melanogaster, GI21357739, Length=689, Percent_Identity=34.2525399129173, Blast_Score=358, Evalue=5e-99,
Organism=Drosophila melanogaster, GI17647529, Length=418, Percent_Identity=36.8421052631579, Blast_Score=265, Evalue=5e-71,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 74147; Mature: 74016

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEADRNPRQFRAEVRKVLHILTNSLYTNREIFLRELISNASDALDKLRFRINRGESPRL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDLPLEIRISLDKEAKTITIADTGLGMTADELAEHLGTIAKSGSEQFLADIAAEKAAKAT
CCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
SASGKDDTADEEQNAGAEADATNIIGRFGVGFYSVFMVAEKVTVTSRPAFGEDSAAHTWT
CCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCC
SDGLGTYTVAPAEGDEPQRGTVITAWLKDDAVEFLEKFRVESAIRKHSAFVPFPVLVDGE
CCCCCEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCC
QVNTQPALWREPKFSVTQEQYAAFYKALTYDSKDPLDVLHFSVDAPVQFNALFFIPDNAQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHEEEECCCCEEEEEEEEECCCCH
DFFGADRDFWGLDLYARRVLIQHRNKELIPEYLAFLKGVVDTEDLPLNISRETLQENVVL
HHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
RKINQVIIKQTLGHLEKLAKNDAEKYAAFWRLHGKVFKLGYHDFANRERVTALLRFNSST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCHHHCCHHHHHHHEEECCCH
LADAEALTSLDEYMDRAPEGQKTFWYVAAPNREAARLNPHMERFRQKGIEVLYLFEPIDE
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHCCHHHHHHHHCCCEEEEEECHHHH
FVMDGLGRYKEWDFRSVETAADDALKDFSDKESPTREAAAPLSDEDSASFDGLLTRMKEV
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHH
LGDKVTEVRVSHRLADSPAVLVSPDGGLSSSMEKLLKVMQKDDSLPVKVLEVNRDHPLLR
HCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHH
NMLRMFKADSSDRILAEMTQSLFDASLLLDGYLKDPQALAARTGKLLEEAAAWYTEVRKI
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AEADRNPRQFRAEVRKVLHILTNSLYTNREIFLRELISNASDALDKLRFRINRGESPRL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PDLPLEIRISLDKEAKTITIADTGLGMTADELAEHLGTIAKSGSEQFLADIAAEKAAKAT
CCCCEEEEEEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
SASGKDDTADEEQNAGAEADATNIIGRFGVGFYSVFMVAEKVTVTSRPAFGEDSAAHTWT
CCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCC
SDGLGTYTVAPAEGDEPQRGTVITAWLKDDAVEFLEKFRVESAIRKHSAFVPFPVLVDGE
CCCCCEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCC
QVNTQPALWREPKFSVTQEQYAAFYKALTYDSKDPLDVLHFSVDAPVQFNALFFIPDNAQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHEEEECCCCEEEEEEEEECCCCH
DFFGADRDFWGLDLYARRVLIQHRNKELIPEYLAFLKGVVDTEDLPLNISRETLQENVVL
HHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
RKINQVIIKQTLGHLEKLAKNDAEKYAAFWRLHGKVFKLGYHDFANRERVTALLRFNSST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHEEECCHHHCCHHHHHHHEEECCCH
LADAEALTSLDEYMDRAPEGQKTFWYVAAPNREAARLNPHMERFRQKGIEVLYLFEPIDE
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHCCHHHHHHHHCCCEEEEEECHHHH
FVMDGLGRYKEWDFRSVETAADDALKDFSDKESPTREAAAPLSDEDSASFDGLLTRMKEV
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHH
LGDKVTEVRVSHRLADSPAVLVSPDGGLSSSMEKLLKVMQKDDSLPVKVLEVNRDHPLLR
HCCHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHH
NMLRMFKADSSDRILAEMTQSLFDASLLLDGYLKDPQALAARTGKLLEEAAAWYTEVRKI
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA