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The map label for this gene is pyrK [H]

Identifier: 220905461

GI number: 220905461

Start: 2651228

End: 2652037

Strand: Direct

Name: pyrK [H]

Synonym: Ddes_2199

Alternate gene names: 220905461

Gene position: 2651228-2652037 (Clockwise)

Preceding gene: 220905459

Following gene: 220905462

Centisome position: 92.27

GC content: 59.63

Gene sequence:

>810_bases
ATGTCGCAACCAACTTCATGCGAGCTGAGTGTCCTGGACCTTGTGCCCTTTGGGCAAACCGGCAACGAAAGCCGCTTCTT
CGCACTGCGCCTTACCCGCCCCGAATGGACCAAGTGGCGGCCGGGCCAGTTTGTCATGATCCGTCCCCAGTCTTTCGGGC
TTGAAATCCCCTGGGCACGGCCCCTCGGCATATGCCATATGACCGCCCGCCACATGATCTGTTTTTTTCAGGTTGTGGGC
AAAGGCACAAAGCGCATGTCCGAACTGCGCCCCGGTGACAGGGTGCGCGCATGGGGTCCCCTCGGCAACGGCTTCGTCAC
CGAACCCGATACTCCCACGCTGCTGCTGGCCGGGGGCATGGGCATTGTGCCTTTTGTGGGCTATGTGAGCGAGCATCCCA
AGCCCTGGAACGTCACGATGCTTTTCGGCCATCGCGAATCCATAAGCTGTTATCCCGTGGACAGCATCAATGAACATGTG
CCGCTTGACAGCCTGCGCGAGACCGTACCCGGCGATCTGGACAATTTTATATTTTCCATACAGGAGCGCATGACGGAATA
CGCCGAACAAAAAGGCCTTGTTCTGGCCTGCGGCCCCACGCCGTTCATGCGGACCGTGCAAAAATTCGCCGCCGAACTGG
GCGTGCGCTGCCAGCTTTCTCTCGAAAACCGCATGGCCTGCGGCGTGGGAGCCTGCCTTGGCTGCGTGACCAAAACAACA
GAAGCCTGGCCCGTACCCGCCAAACGCGGCAGCCAGGTACAGGCGTGCAACCACGGCCCTGTATTCTGGTCAGACCAGAT
AGAACTGTAG

Upstream 100 bases:

>100_bases
TCGCCCCTGCAAAAGCCACATTAAAAAAGGGGGTTTAATTATCCCGTTTACCCGGCAGCGCCCGGTTGACCAGTTGACCA
AGTACGCCTATAGTCAGCGC

Downstream 100 bases:

>100_bases
TCCGTTGAAAAAGAGCGCACGGGGCATTGCAGCACTGTTTTGCCCCGCAGCGCCGTTTGTAGCCGGAACATGCGTCCCAC
GCGCCTGCCCGGCGCGACCG

Product: oxidoreductase FAD/NAD(P)-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 268

Protein sequence:

>269_residues
MSQPTSCELSVLDLVPFGQTGNESRFFALRLTRPEWTKWRPGQFVMIRPQSFGLEIPWARPLGICHMTARHMICFFQVVG
KGTKRMSELRPGDRVRAWGPLGNGFVTEPDTPTLLLAGGMGIVPFVGYVSEHPKPWNVTMLFGHRESISCYPVDSINEHV
PLDSLRETVPGDLDNFIFSIQERMTEYAEQKGLVLACGPTPFMRTVQKFAAELGVRCQLSLENRMACGVGACLGCVTKTT
EAWPVPAKRGSQVQACNHGPVFWSDQIEL

Sequences:

>Translated_269_residues
MSQPTSCELSVLDLVPFGQTGNESRFFALRLTRPEWTKWRPGQFVMIRPQSFGLEIPWARPLGICHMTARHMICFFQVVG
KGTKRMSELRPGDRVRAWGPLGNGFVTEPDTPTLLLAGGMGIVPFVGYVSEHPKPWNVTMLFGHRESISCYPVDSINEHV
PLDSLRETVPGDLDNFIFSIQERMTEYAEQKGLVLACGPTPFMRTVQKFAAELGVRCQLSLENRMACGVGACLGCVTKTT
EAWPVPAKRGSQVQACNHGPVFWSDQIEL
>Mature_268_residues
SQPTSCELSVLDLVPFGQTGNESRFFALRLTRPEWTKWRPGQFVMIRPQSFGLEIPWARPLGICHMTARHMICFFQVVGK
GTKRMSELRPGDRVRAWGPLGNGFVTEPDTPTLLLAGGMGIVPFVGYVSEHPKPWNVTMLFGHRESISCYPVDSINEHVP
LDSLRETVPGDLDNFIFSIQERMTEYAEQKGLVLACGPTPFMRTVQKFAAELGVRCQLSLENRMACGVGACLGCVTKTTE
AWPVPAKRGSQVQACNHGPVFWSDQIEL

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR000951
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 29972; Mature: 29841

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPTSCELSVLDLVPFGQTGNESRFFALRLTRPEWTKWRPGQFVMIRPQSFGLEIPWAR
CCCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCHHCCEECCCCC
PLGICHMTARHMICFFQVVGKGTKRMSELRPGDRVRAWGPLGNGFVTEPDTPTLLLAGGM
CCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEECCCCCCEEECCCCCEEEEECCC
GIVPFVGYVSEHPKPWNVTMLFGHRESISCYPVDSINEHVPLDSLRETVPGDLDNFIFSI
CHHHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHH
QERMTEYAEQKGLVLACGPTPFMRTVQKFAAELGVRCQLSLENRMACGVGACLGCVTKTT
HHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCC
EAWPVPAKRGSQVQACNHGPVFWSDQIEL
CCCCCCCCCCCEEEECCCCCEEECCCCCC
>Mature Secondary Structure 
SQPTSCELSVLDLVPFGQTGNESRFFALRLTRPEWTKWRPGQFVMIRPQSFGLEIPWAR
CCCCCCCEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCCEEEECCHHCCEECCCCC
PLGICHMTARHMICFFQVVGKGTKRMSELRPGDRVRAWGPLGNGFVTEPDTPTLLLAGGM
CCHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEECCCCCCEEECCCCCEEEEECCC
GIVPFVGYVSEHPKPWNVTMLFGHRESISCYPVDSINEHVPLDSLRETVPGDLDNFIFSI
CHHHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCCCCCCHHHHHHHCCCCHHHHHHHH
QERMTEYAEQKGLVLACGPTPFMRTVQKFAAELGVRCQLSLENRMACGVGACLGCVTKTT
HHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHHHCCC
EAWPVPAKRGSQVQACNHGPVFWSDQIEL
CCCCCCCCCCCEEEECCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]