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The map label for this gene is cobL [H]

Identifier: 220905241

GI number: 220905241

Start: 2381945

End: 2383747

Strand: Direct

Name: cobL [H]

Synonym: Ddes_1979

Alternate gene names: 220905241

Gene position: 2381945-2383747 (Clockwise)

Preceding gene: 220905240

Following gene: 220905242

Centisome position: 82.9

GC content: 66.78

Gene sequence:

>1803_bases
ATGAAAAATCAGGTTGCACTGCCCGGCATTGCCGTGCCCTCCCCCACACCGAGCGAAGACGCGAGCCGGACTGCAGCGAC
TGGCCCCCCGGAGACGCGTGAGGCCCTGTCCACCGCGGAACATGCCGTCCCTTCTGCCGTTACGGACGCAGCAGCGCAGG
TTACCGCCGCCCGCGACACGGCCGGCACAGCACGCGATACTCCCGCAGAGGCCCCCTCTGACAACGGCCAGCCCCCGGCA
GACGATGCCCCCGCAGAAGCCCCGGCACTTGTGGCCGCACCGTCACAGTCCAGGCAGAAAAACCCGGTGGAAAGCAACCC
CGTTGCCTCCAGGGCTGTAAAAAAACGGCGCAAGCCGGCACAACAGCCGCCGCAGGAGCAAACCCCACCCGCCCAGCCGG
ACGATTGGCCGCCCATGTCTGAAATTCTGCAATCCTGCTTTGTTTTTGAGCCTACTACAGCGCAGCCCAGCCCCATCACG
GTACTTGGCCTGGACTGCGGGCGCCCGCGTGGACTTGCGTCCCTGACAGCCGAGCAGAAATTGCTGTTGCACAAGGCCGA
TGTGATCTGCGGCGGCCGCCAGATACTGCACGACCTGACGGGGCATGCCCCCGAAGATGGACCGGGCGGCACAGCCCCCG
GCCCAGATGGCGAAGCAGCCAGACAGGAAACGCTCAACGCCCGCCTGCTGCCCCTGAGTACGCCGCTGGAACCCGTCATC
ACCCGCCTGAGCCAGATGCGCGCCGCCGGTGAACGTGTCATCATGCTGGCCGACGGCGACCCCCTGCTTTTCGGCATCGG
GGGAACACTTGTGCGCCTTCTCGGGCAGGATGCCGTAGAGCTTGTGCCTGCGGTCAGCTCTCTGCAACAGGCCTGCGCCC
GCCTGGCCTTGCCCTGGCACAGGGTGATCTGCCTGTCGCTGCACGGACGCGATGACCTTGGGCCGCTCAATGCGGCTGTA
AGCAAAAATGCACCGCTCTGCGTACTTACCGACGCCCGCATGTCGCCGGACGTGCTGGCCCGCCACCTGCTGGACCGGGG
GGTGGACTGGTTCACCGTGCATGTTTTCGAGCGCATGGGCGCGCCGGACGAGCAAGGCAGTCACCTGAGCATGGCTCAGG
CCGCCGGAGGTGTTTTTGGCCCGGCCTGCACCCTTGTGCTTGTTCCCGGCGACGCGCCCCGCCGCGCGCGGCTCGGCCTC
AACGCCGGAGAACTGGCTGTGGACAGGGGGCTGATCAGCAAAAAACCCGTGCGCGCAGCTGCTCTGGCTCTTCTGCAGAT
AGAGCCGCACCATGTGGTGTGGGATGTCGGTTCCGGCTCCGGAGCCGTGGCCCTTGAAGCCACGGTACTGGCGCACGAAG
GCCGCGTGGTGGCGGTTGAGCGCTCTGTGGGCCGCGCCATGAGCATCCAGGAAAACCGCCGCCGCTTTGGCGCGGCCACT
CTGGATGTACGCCTGGGGCAGGCCCCGGAGTGCCTGCCCTCGCTGCCCGATCCGCACCGTGTTTTTGTCGGTGGCGGGCT
TTCCGGCGAAGATGGAGAAGATCTCCTGGGGCATGTCTGCCTGCGCCTGCCCCCTGGCGGGCGCGTGGTGGCAAGCTGCG
TTCTGCTGGACACCCTGTGCCTGTGCCGCCGCTTTTTTGAACGCCTCGGCTGGCCGGTGGAGATCAGTCAGATTCAGGCT
TCCGAAGGCAGGGAACTGGGCGGCGATGTGCATCTGGCCGCCATGAATCCCGTATTTCTGCTGGCGGCCCAAAAACCGGC
CCCGGAGAGCACCGGCCGCGCCGGTCAGGGGGCGCGCTCATGA

Upstream 100 bases:

>100_bases
GGCAGGTGGCCGCCAAAGCCGCTGCAGTGGCGGCAAAATTTGCGGGACACCCCGTGCGGCTGCACCTTTTTCACACCGAC
GGCAGGGAATTACTGGCATT

Downstream 100 bases:

>100_bases
GACGCATCCCGAGCAGCGGCAACAGCACACCCGGCAGACAACAGACAGCAGGCGCCATGACTACCTGCAAACATGACGAA
AAGAATACGGCCCATATGAC

Product: precorrin-6y C5,15-methyltransferase subunit CbiE

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 600; Mature: 600

Protein sequence:

>600_residues
MKNQVALPGIAVPSPTPSEDASRTAATGPPETREALSTAEHAVPSAVTDAAAQVTAARDTAGTARDTPAEAPSDNGQPPA
DDAPAEAPALVAAPSQSRQKNPVESNPVASRAVKKRRKPAQQPPQEQTPPAQPDDWPPMSEILQSCFVFEPTTAQPSPIT
VLGLDCGRPRGLASLTAEQKLLLHKADVICGGRQILHDLTGHAPEDGPGGTAPGPDGEAARQETLNARLLPLSTPLEPVI
TRLSQMRAAGERVIMLADGDPLLFGIGGTLVRLLGQDAVELVPAVSSLQQACARLALPWHRVICLSLHGRDDLGPLNAAV
SKNAPLCVLTDARMSPDVLARHLLDRGVDWFTVHVFERMGAPDEQGSHLSMAQAAGGVFGPACTLVLVPGDAPRRARLGL
NAGELAVDRGLISKKPVRAAALALLQIEPHHVVWDVGSGSGAVALEATVLAHEGRVVAVERSVGRAMSIQENRRRFGAAT
LDVRLGQAPECLPSLPDPHRVFVGGGLSGEDGEDLLGHVCLRLPPGGRVVASCVLLDTLCLCRRFFERLGWPVEISQIQA
SEGRELGGDVHLAAMNPVFLLAAQKPAPESTGRAGQGARS

Sequences:

>Translated_600_residues
MKNQVALPGIAVPSPTPSEDASRTAATGPPETREALSTAEHAVPSAVTDAAAQVTAARDTAGTARDTPAEAPSDNGQPPA
DDAPAEAPALVAAPSQSRQKNPVESNPVASRAVKKRRKPAQQPPQEQTPPAQPDDWPPMSEILQSCFVFEPTTAQPSPIT
VLGLDCGRPRGLASLTAEQKLLLHKADVICGGRQILHDLTGHAPEDGPGGTAPGPDGEAARQETLNARLLPLSTPLEPVI
TRLSQMRAAGERVIMLADGDPLLFGIGGTLVRLLGQDAVELVPAVSSLQQACARLALPWHRVICLSLHGRDDLGPLNAAV
SKNAPLCVLTDARMSPDVLARHLLDRGVDWFTVHVFERMGAPDEQGSHLSMAQAAGGVFGPACTLVLVPGDAPRRARLGL
NAGELAVDRGLISKKPVRAAALALLQIEPHHVVWDVGSGSGAVALEATVLAHEGRVVAVERSVGRAMSIQENRRRFGAAT
LDVRLGQAPECLPSLPDPHRVFVGGGLSGEDGEDLLGHVCLRLPPGGRVVASCVLLDTLCLCRRFFERLGWPVEISQIQA
SEGRELGGDVHLAAMNPVFLLAAQKPAPESTGRAGQGARS
>Mature_600_residues
MKNQVALPGIAVPSPTPSEDASRTAATGPPETREALSTAEHAVPSAVTDAAAQVTAARDTAGTARDTPAEAPSDNGQPPA
DDAPAEAPALVAAPSQSRQKNPVESNPVASRAVKKRRKPAQQPPQEQTPPAQPDDWPPMSEILQSCFVFEPTTAQPSPIT
VLGLDCGRPRGLASLTAEQKLLLHKADVICGGRQILHDLTGHAPEDGPGGTAPGPDGEAARQETLNARLLPLSTPLEPVI
TRLSQMRAAGERVIMLADGDPLLFGIGGTLVRLLGQDAVELVPAVSSLQQACARLALPWHRVICLSLHGRDDLGPLNAAV
SKNAPLCVLTDARMSPDVLARHLLDRGVDWFTVHVFERMGAPDEQGSHLSMAQAAGGVFGPACTLVLVPGDAPRRARLGL
NAGELAVDRGLISKKPVRAAALALLQIEPHHVVWDVGSGSGAVALEATVLAHEGRVVAVERSVGRAMSIQENRRRFGAAT
LDVRLGQAPECLPSLPDPHRVFVGGGLSGEDGEDLLGHVCLRLPPGGRVVASCVLLDTLCLCRRFFERLGWPVEISQIQA
SEGRELGGDVHLAAMNPVFLLAAQKPAPESTGRAGQGARS

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 62787; Mature: 62787

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNQVALPGIAVPSPTPSEDASRTAATGPPETREALSTAEHAVPSAVTDAAAQVTAARDT
CCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
AGTARDTPAEAPSDNGQPPADDAPAEAPALVAAPSQSRQKNPVESNPVASRAVKKRRKPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCC
QQPPQEQTPPAQPDDWPPMSEILQSCFVFEPTTAQPSPITVLGLDCGRPRGLASLTAEQK
CCCCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHH
LLLHKADVICGGRQILHDLTGHAPEDGPGGTAPGPDGEAARQETLNARLLPLSTPLEPVI
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCHHHHH
TRLSQMRAAGERVIMLADGDPLLFGIGGTLVRLLGQDAVELVPAVSSLQQACARLALPWH
HHHHHHHHCCCEEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
RVICLSLHGRDDLGPLNAAVSKNAPLCVLTDARMSPDVLARHLLDRGVDWFTVHVFERMG
EEEEEEECCCCCCCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEHHHHHHCC
APDEQGSHLSMAQAAGGVFGPACTLVLVPGDAPRRARLGLNAGELAVDRGLISKKPVRAA
CCCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCHHHCCCCCCHHHHHCCCCCCCCHHHH
ALALLQIEPHHVVWDVGSGSGAVALEATVLAHEGRVVAVERSVGRAMSIQENRRRFGAAT
HEEHEEECCCEEEEECCCCCCEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCEE
LDVRLGQAPECLPSLPDPHRVFVGGGLSGEDGEDLLGHVCLRLPPGGRVVASCVLLDTLC
EEEECCCCCHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHH
LCRRFFERLGWPVEISQIQASEGRELGGDVHLAAMNPVFLLAAQKPAPESTGRAGQGARS
HHHHHHHHCCCCEEEEHEECCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKNQVALPGIAVPSPTPSEDASRTAATGPPETREALSTAEHAVPSAVTDAAAQVTAARDT
CCCCCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
AGTARDTPAEAPSDNGQPPADDAPAEAPALVAAPSQSRQKNPVESNPVASRAVKKRRKPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCC
QQPPQEQTPPAQPDDWPPMSEILQSCFVFEPTTAQPSPITVLGLDCGRPRGLASLTAEQK
CCCCCCCCCCCCCCCCCCHHHHHHHHEEECCCCCCCCCEEEEECCCCCCCCHHHHHHHHH
LLLHKADVICGGRQILHDLTGHAPEDGPGGTAPGPDGEAARQETLNARLLPLSTPLEPVI
HHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCHHHHH
TRLSQMRAAGERVIMLADGDPLLFGIGGTLVRLLGQDAVELVPAVSSLQQACARLALPWH
HHHHHHHHCCCEEEEEECCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
RVICLSLHGRDDLGPLNAAVSKNAPLCVLTDARMSPDVLARHLLDRGVDWFTVHVFERMG
EEEEEEECCCCCCCCHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEHHHHHHCC
APDEQGSHLSMAQAAGGVFGPACTLVLVPGDAPRRARLGLNAGELAVDRGLISKKPVRAA
CCCCCCCCCHHHHHCCCCCCCEEEEEEECCCCCCHHHCCCCCCHHHHHCCCCCCCCHHHH
ALALLQIEPHHVVWDVGSGSGAVALEATVLAHEGRVVAVERSVGRAMSIQENRRRFGAAT
HEEHEEECCCEEEEECCCCCCEEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHCCEE
LDVRLGQAPECLPSLPDPHRVFVGGGLSGEDGEDLLGHVCLRLPPGGRVVASCVLLDTLC
EEEECCCCCHHCCCCCCCCEEEEECCCCCCCHHHHHHHHHEECCCCCHHHHHHHHHHHHH
LCRRFFERLGWPVEISQIQASEGRELGGDVHLAAMNPVFLLAAQKPAPESTGRAGQGARS
HHHHHHHHCCCCEEEEHEECCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]