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The map label for this gene is cmpR [H]

Identifier: 220905118

GI number: 220905118

Start: 2236846

End: 2237772

Strand: Reverse

Name: cmpR [H]

Synonym: Ddes_1855

Alternate gene names: 220905118

Gene position: 2237772-2236846 (Counterclockwise)

Preceding gene: 220905124

Following gene: 220905111

Centisome position: 77.88

GC content: 56.63

Gene sequence:

>927_bases
ATGAACATTGATCACTTGAAAACATTTCATAAAATTGCCGAAACCGGCAATTTTACCCAGGCCGCGCGCGACCTTTTTCT
TACACAGCCCGCAGTGAGCATGCAGGTACAGAGCCTTGAGAACAGTCTTGGCGTTCCCCTGTTCGACCGGTCGCGACGCA
AGGTGAACCTCACAAGCGAAGGGCGTGTGCTCTACGAATACACCCAGCGTATATTCAGTCTTGTCAACCAGATGCAGGAC
GAATTCCAGAGCCTCAGCCAGCTTGATACCGGCCGCCTCGTGCTTGGCGCATCGGCCATTATGAGCGCCTACTATCTGCC
CGGTTATATGGTACTTTTTCATCAGCGTCATCCCGGCGTCACTCTGGATCTGGCTGTGCACAATTCGCACGTCATTGCCG
AAAAAGTATACCGGGGAGAGCTGGAGATCGGTTTTTGCGGCTCATCGCCGTCGCATCCCAATCTTCGCGCACATTTTTTG
CACCGTGAGCCGCTTATTGTGGTTGCGGGGCGCAAGTCCGCCCTGGCGCAAAAGGACGGCCCGGTCTGTGCCGATGACCT
GCTGGCGCACCCCTTTATCCTGCGGGAGCAGGGAACCCGCGTGACCAACAAGGTGCAGGAATGGTTCAAGACACATGCCG
GTCGCCCCGAACGGCCGTCATTCATGACCGTGGACAATATGGAGGTTGCCAAGCAACTGGTGATCAACGGGCTGGGGGTT
ACGGCCCTGCCGCGGTACGCGGCCGCTCTGGAACTGGCCGCGGGACAGCTGACGCAGTTGCGGCTGGAATCTTTTGACCT
GCATGTGAACTATTCGCTGGTCTATATGGAAGGGCAGCGCCTGAGCCGTACGGTAACGCATTTTCTGGCGCTGCTTTTTG
AGCTTGGCGTACCTTTGCCCGAAGAAATTCTGTCGCGCCTGCCATAG

Upstream 100 bases:

>100_bases
CGGCAAAGGCGTACCACGGCGACGCGGTTGACAATCACCGTCATCTGCACGAGCATTTGCGGACATTGAGCATTTTTCAA
CAAGGCCGGTTGATGCCCGC

Downstream 100 bases:

>100_bases
GTCTGTCTGCCGTCTTCCTGCACCGGTCCAGCCGCGCCCGGCAGTGGACACGAGTCAGACTGCTTTCTGTCGATACACTA
CATTGAAAGCGCCCCGTTCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MNIDHLKTFHKIAETGNFTQAARDLFLTQPAVSMQVQSLENSLGVPLFDRSRRKVNLTSEGRVLYEYTQRIFSLVNQMQD
EFQSLSQLDTGRLVLGASAIMSAYYLPGYMVLFHQRHPGVTLDLAVHNSHVIAEKVYRGELEIGFCGSSPSHPNLRAHFL
HREPLIVVAGRKSALAQKDGPVCADDLLAHPFILREQGTRVTNKVQEWFKTHAGRPERPSFMTVDNMEVAKQLVINGLGV
TALPRYAAALELAAGQLTQLRLESFDLHVNYSLVYMEGQRLSRTVTHFLALLFELGVPLPEEILSRLP

Sequences:

>Translated_308_residues
MNIDHLKTFHKIAETGNFTQAARDLFLTQPAVSMQVQSLENSLGVPLFDRSRRKVNLTSEGRVLYEYTQRIFSLVNQMQD
EFQSLSQLDTGRLVLGASAIMSAYYLPGYMVLFHQRHPGVTLDLAVHNSHVIAEKVYRGELEIGFCGSSPSHPNLRAHFL
HREPLIVVAGRKSALAQKDGPVCADDLLAHPFILREQGTRVTNKVQEWFKTHAGRPERPSFMTVDNMEVAKQLVINGLGV
TALPRYAAALELAAGQLTQLRLESFDLHVNYSLVYMEGQRLSRTVTHFLALLFELGVPLPEEILSRLP
>Mature_308_residues
MNIDHLKTFHKIAETGNFTQAARDLFLTQPAVSMQVQSLENSLGVPLFDRSRRKVNLTSEGRVLYEYTQRIFSLVNQMQD
EFQSLSQLDTGRLVLGASAIMSAYYLPGYMVLFHQRHPGVTLDLAVHNSHVIAEKVYRGELEIGFCGSSPSHPNLRAHFL
HREPLIVVAGRKSALAQKDGPVCADDLLAHPFILREQGTRVTNKVQEWFKTHAGRPERPSFMTVDNMEVAKQLVINGLGV
TALPRYAAALELAAGQLTQLRLESFDLHVNYSLVYMEGQRLSRTVTHFLALLFELGVPLPEEILSRLP

Specific function: Activates transcription of the cmpABCD operon under carbon dioxide-limited conditions. Specifically binds to the cmpR- cmpA intergenic region [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788481, Length=300, Percent_Identity=30.3333333333333, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI157672245, Length=172, Percent_Identity=34.3023255813954, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI1788887, Length=248, Percent_Identity=30.241935483871, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI87082132, Length=266, Percent_Identity=26.6917293233083, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI145693193, Length=304, Percent_Identity=28.2894736842105, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790208, Length=246, Percent_Identity=28.0487804878049, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1786401, Length=294, Percent_Identity=25.1700680272109, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1789639, Length=262, Percent_Identity=26.7175572519084, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787806, Length=250, Percent_Identity=25.2, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1788748, Length=178, Percent_Identity=28.6516853932584, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI145693105, Length=248, Percent_Identity=25, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790399, Length=251, Percent_Identity=25.0996015936255, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789204, Length=145, Percent_Identity=27.5862068965517, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787879, Length=256, Percent_Identity=27.34375, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787128, Length=131, Percent_Identity=30.5343511450382, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI48994962, Length=163, Percent_Identity=27.6073619631902, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787949, Length=264, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081904, Length=201, Percent_Identity=27.363184079602, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788297, Length=250, Percent_Identity=25.2, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787601, Length=142, Percent_Identity=27.4647887323944, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789173, Length=257, Percent_Identity=25.6809338521401, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87081978, Length=272, Percent_Identity=25.3676470588235, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786448, Length=266, Percent_Identity=25.5639097744361, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788706, Length=261, Percent_Identity=25.6704980842912, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788296, Length=243, Percent_Identity=24.6913580246914, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1790262, Length=252, Percent_Identity=25, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790783, Length=313, Percent_Identity=23.3226837060703, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34587; Mature: 34587

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIDHLKTFHKIAETGNFTQAARDLFLTQPAVSMQVQSLENSLGVPLFDRSRRKVNLTSE
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCC
GRVLYEYTQRIFSLVNQMQDEFQSLSQLDTGRLVLGASAIMSAYYLPGYMVLFHQRHPGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCEEEEEEECCCCE
TLDLAVHNSHVIAEKVYRGELEIGFCGSSPSHPNLRAHFLHREPLIVVAGRKSALAQKDG
EEEEEECCCHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCEEEEECCCHHHHCCCC
PVCADDLLAHPFILREQGTRVTNKVQEWFKTHAGRPERPSFMTVDNMEVAKQLVINGLGV
CCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHCCCCH
TALPRYAAALELAAGQLTQLRLESFDLHVNYSLVYMEGQRLSRTVTHFLALLFELGVPLP
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECHHHHHHHHHHHHHHHHHCCCCH
EEILSRLP
HHHHHHCC
>Mature Secondary Structure
MNIDHLKTFHKIAETGNFTQAARDLFLTQPAVSMQVQSLENSLGVPLFDRSRRKVNLTSE
CCCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCC
GRVLYEYTQRIFSLVNQMQDEFQSLSQLDTGRLVLGASAIMSAYYLPGYMVLFHQRHPGV
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHCCCEEEEEEECCCCE
TLDLAVHNSHVIAEKVYRGELEIGFCGSSPSHPNLRAHFLHREPLIVVAGRKSALAQKDG
EEEEEECCCHHHHHHHHCCCEEEEECCCCCCCCCCEEEEECCCCEEEEECCCHHHHCCCC
PVCADDLLAHPFILREQGTRVTNKVQEWFKTHAGRPERPSFMTVDNMEVAKQLVINGLGV
CCCHHHHHHCCEEEECCCCHHHHHHHHHHHHHCCCCCCCCEEEECCHHHHHHHHHCCCCH
TALPRYAAALELAAGQLTQLRLESFDLHVNYSLVYMEGQRLSRTVTHFLALLFELGVPLP
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEEEEECHHHHHHHHHHHHHHHHHCCCCH
EEILSRLP
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]