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The map label for this gene is hyfC [H]

Identifier: 220904937

GI number: 220904937

Start: 2008342

End: 2009193

Strand: Reverse

Name: hyfC [H]

Synonym: Ddes_1672

Alternate gene names: 220904937

Gene position: 2009193-2008342 (Counterclockwise)

Preceding gene: 220904938

Following gene: 220904936

Centisome position: 69.92

GC content: 56.34

Gene sequence:

>852_bases
ATGCTGTCCATCCTCAGTGCTGTCGGCGGATTGATATTGTCGCCCCTGGTGGGGGGCCTGCTTACCGGGGTTGACCGCCG
TCTCACGGCGCGGCTGCAATCGCGCCTGGGGCCGCCCCTGCTTCAGCCTTTTTACGATGTCTTCAAGCTTTTCGGTAAAG
AAGCCAGCGTAACCAATGCCTGGCTTGTATTCAGCGCCTATATGACGCTTATCTCCTCGGCTTTGGCACTGCTCATATTC
TTTATGGGTGGCGACCTGCTGCTGCTTTTCTTTGTGCTTACGGTGGGTGCTGTTTTTCAGGTGGTGGGCGCCCTGTGTGT
TCCTTCGCCCTACAGCAACGTGGGCGCGCAGCGCGAGCTTCTGCTCATGCTGGCCTATGAACCCATACTGATTTTGGTTT
TTGTCGGCTTTGCCATGTGCACGGGATCTTTTTCCATTGAGGCCGTGTTTGCCCAGGACCAGCCCCTGCTGCTCAAGATG
CCCCTGCTGTTTCTGGCGCTGGGCTACGCCCTGACCATCAAGCTGCGCAAGTCGCCCTTTGATATTTCTGCCAGCCATCA
TGGCCATCAGGAACTGGTAAAGGGTGTGCAGACGGAATATTCCGGTCCTTACCTGGGCATCATTGAGCTGGCCCACTGGC
TTGACCTTGTGCTTATTCTCGGTTTGTGCGCCATGTTCTGGCACACCAGCGTCATTGGCATGGCCACGCTGGTGGCGGCT
TCGCTGTTTACAGAAATCCTCATCGACAACATCACCGCCCGGCTTACCTGGCAGTGGATGGTGCAGAAGAAATCCCTGTT
GCTCGGCATGGGGCTGGCCCTGGTTAATCTTTTATGGCTGTACGTGGCGTAA

Upstream 100 bases:

>100_bases
ACTTTTACCTGACCCAGTACTTTGGCGAAGGCACTATAACACGGGCCATTGATATTATATCCACGGCCTTTCTCATCGTC
CTGGTAGGAGGTCTGCTCTA

Downstream 100 bases:

>100_bases
GGAGGCAGGCATATGGGTTTTGTAGACAAAATGATAAAGCGGAGCCGGCTCAAGTCGCCATGGATTGTCCATTTTGACTG
CGGCTCCTGCAACGGTTGCG

Product: respiratory-chain NADH dehydrogenase subunit 1

Products: H2; oxidized ferredoxin [C]

Alternate protein names: NA

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MLSILSAVGGLILSPLVGGLLTGVDRRLTARLQSRLGPPLLQPFYDVFKLFGKEASVTNAWLVFSAYMTLISSALALLIF
FMGGDLLLLFFVLTVGAVFQVVGALCVPSPYSNVGAQRELLLMLAYEPILILVFVGFAMCTGSFSIEAVFAQDQPLLLKM
PLLFLALGYALTIKLRKSPFDISASHHGHQELVKGVQTEYSGPYLGIIELAHWLDLVLILGLCAMFWHTSVIGMATLVAA
SLFTEILIDNITARLTWQWMVQKKSLLLGMGLALVNLLWLYVA

Sequences:

>Translated_283_residues
MLSILSAVGGLILSPLVGGLLTGVDRRLTARLQSRLGPPLLQPFYDVFKLFGKEASVTNAWLVFSAYMTLISSALALLIF
FMGGDLLLLFFVLTVGAVFQVVGALCVPSPYSNVGAQRELLLMLAYEPILILVFVGFAMCTGSFSIEAVFAQDQPLLLKM
PLLFLALGYALTIKLRKSPFDISASHHGHQELVKGVQTEYSGPYLGIIELAHWLDLVLILGLCAMFWHTSVIGMATLVAA
SLFTEILIDNITARLTWQWMVQKKSLLLGMGLALVNLLWLYVA
>Mature_283_residues
MLSILSAVGGLILSPLVGGLLTGVDRRLTARLQSRLGPPLLQPFYDVFKLFGKEASVTNAWLVFSAYMTLISSALALLIF
FMGGDLLLLFFVLTVGAVFQVVGALCVPSPYSNVGAQRELLLMLAYEPILILVFVGFAMCTGSFSIEAVFAQDQPLLLKM
PLLFLALGYALTIKLRKSPFDISASHHGHQELVKGVQTEYSGPYLGIIELAHWLDLVLILGLCAMFWHTSVIGMATLVAA
SLFTEILIDNITARLTWQWMVQKKSLLLGMGLALVNLLWLYVA

Specific function: Unknown

COG id: COG0650

COG function: function code C; Formate hydrogenlyase subunit 4

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Escherichia coli, GI87082115, Length=220, Percent_Identity=36.3636363636364, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1789077, Length=213, Percent_Identity=30.5164319248826, Blast_Score=85, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 30938; Mature: 30938

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSILSAVGGLILSPLVGGLLTGVDRRLTARLQSRLGPPLLQPFYDVFKLFGKEASVTNA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHH
WLVFSAYMTLISSALALLIFFMGGDLLLLFFVLTVGAVFQVVGALCVPSPYSNVGAQREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHH
LLMLAYEPILILVFVGFAMCTGSFSIEAVFAQDQPLLLKMPLLFLALGYALTIKLRKSPF
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEECCCC
DISASHHGHQELVKGVQTEYSGPYLGIIELAHWLDLVLILGLCAMFWHTSVIGMATLVAA
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFTEILIDNITARLTWQWMVQKKSLLLGMGLALVNLLWLYVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSILSAVGGLILSPLVGGLLTGVDRRLTARLQSRLGPPLLQPFYDVFKLFGKEASVTNA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHH
WLVFSAYMTLISSALALLIFFMGGDLLLLFFVLTVGAVFQVVGALCVPSPYSNVGAQREL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHHH
LLMLAYEPILILVFVGFAMCTGSFSIEAVFAQDQPLLLKMPLLFLALGYALTIKLRKSPF
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHEEEEECCCC
DISASHHGHQELVKGVQTEYSGPYLGIIELAHWLDLVLILGLCAMFWHTSVIGMATLVAA
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLFTEILIDNITARLTWQWMVQKKSLLLGMGLALVNLLWLYVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton; reduced ferredoxin [C]

Specific reaction: Proton + reduced ferredoxin = H2 + oxidized ferredoxin [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]