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The map label for this gene is uvsE [H]

Identifier: 220904817

GI number: 220904817

Start: 1856089

End: 1857345

Strand: Direct

Name: uvsE [H]

Synonym: Ddes_1549

Alternate gene names: 220904817

Gene position: 1856089-1857345 (Clockwise)

Preceding gene: 220904816

Following gene: 220904822

Centisome position: 64.59

GC content: 57.12

Gene sequence:

>1257_bases
GTGATACGCTATGGCTTTGCATGCAAAACCGTTGGTCTGCCCGGAGCGGCACAAAGTAGTCTTACCCTGTCGCGTGCAAG
CCGGGACAATCTCCTGTCCGTCAGCCGGAACAATCTTGGTGCGCTGGAAACCATGCTGCGCTACTGCCACAGACAGTCTC
TTGCGCTCATGCGCGTCAGTTCCGATATTATTCCGCTGGCTTCGCACGAAGCGGTGCATTTTGACTGGCAGACCGAACTG
CGGTCCGAGCTTGAAAGCCTGGCCGCCCTTGCCCACCAGAGCGGCGTGCGCCTTTCCATGCACCCAGGCCAGTACACTGT
GCTCAACTCTCCCCGCCCGGATGTGGTGCGCAAGGCTGTGGCCGATCTGGCGTATCATGCGGCTTTTCTTGATGCCCTGC
AGGCCGGGCCGGAGTGCCGCATAATCCTGCACCTTGGCGGCGGCTATGGCGACAGGGAGTCCGCACTGCAACGCCTGCGC
AGCAACCTGGCTGCCTTGCCCGCTTCCATCCTGCAAAGGCTGGCCCTGGAAAACGATGAGCGCATCTATACTATTGAGGA
TGTTCTCGCAGTCTGCCGTGATTTTGATCTGCCTGCCGTTTTTGATATTTTCCATCACGAGCTGAACCCGCCCCCGCATG
GCGACACACAGTACTGGCTTGACCGTGCAGGGGAGACCTGGAACTCACGCAGCGGACGCCAGAAAATCCATTATTCACAA
CAACTGGCGGGCGGCAAGCCGGGTATGCACTCTCTTGCCATTGCCATGCATCCCTTTATGCAACTGCACGGCCTGCTTGA
AGAGCGCGCGCTTGATGTCATGCTGGAGGTCAAAGACAAGAATCTTTCGGCCATCAAATGTGCAAACCTGACCCGGGCGG
GCCTGCCGCGCAAAAACCTCACGGAAGAGTGGGCGCGCTATAAATACCTTATACTTGAACGTAGCCCCGGCGTGTACTCG
GCCATACGCCAGCTGCTCAAAAGCGAAAATCCGACAGCAGAGGCGTTTTACGGCCTGCTCGAAGACGCGCTTGCCTGTCG
TCTGGAACCAGGCAAGGCCAGAAATGCCGCAGAACACGTATGGGGATATGTAAGCAGAAATGCCCCGGCCAGAGAATCCG
CCCGCATACTCAAAGACCTTGAACTTCTGGGCAATGACCTTACGCCGCTGCCCCGCATCAAGCGTAAACTACTGACCTTG
GCGGCGGATAACAACGAAGACTATTTGCTGCACAGCCTCTATTTCTATATAAACTAG

Upstream 100 bases:

>100_bases
CGGCATGGGCGGCATGTACTAAGGCCGGTCCCTGCAGTTTAAACGTCTCTTATCAAAGCCCCCGCGCAAGCGGGGGCTTT
TTTCGCAACAGGAGCATACC

Downstream 100 bases:

>100_bases
CTCTTGTGGCGCACAGATGCGGCACAGCCTCCATCAAAACCGCTGACTGCCTGCGGCTGCATGCAATGGCTCACCCAGGC
GCGTCGCAACCACTCGTTGC

Product: UV-endonuclease UvdE

Products: NA

Alternate protein names: UV-endonuclease; UVED [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MIRYGFACKTVGLPGAAQSSLTLSRASRDNLLSVSRNNLGALETMLRYCHRQSLALMRVSSDIIPLASHEAVHFDWQTEL
RSELESLAALAHQSGVRLSMHPGQYTVLNSPRPDVVRKAVADLAYHAAFLDALQAGPECRIILHLGGGYGDRESALQRLR
SNLAALPASILQRLALENDERIYTIEDVLAVCRDFDLPAVFDIFHHELNPPPHGDTQYWLDRAGETWNSRSGRQKIHYSQ
QLAGGKPGMHSLAIAMHPFMQLHGLLEERALDVMLEVKDKNLSAIKCANLTRAGLPRKNLTEEWARYKYLILERSPGVYS
AIRQLLKSENPTAEAFYGLLEDALACRLEPGKARNAAEHVWGYVSRNAPARESARILKDLELLGNDLTPLPRIKRKLLTL
AADNNEDYLLHSLYFYIN

Sequences:

>Translated_418_residues
MIRYGFACKTVGLPGAAQSSLTLSRASRDNLLSVSRNNLGALETMLRYCHRQSLALMRVSSDIIPLASHEAVHFDWQTEL
RSELESLAALAHQSGVRLSMHPGQYTVLNSPRPDVVRKAVADLAYHAAFLDALQAGPECRIILHLGGGYGDRESALQRLR
SNLAALPASILQRLALENDERIYTIEDVLAVCRDFDLPAVFDIFHHELNPPPHGDTQYWLDRAGETWNSRSGRQKIHYSQ
QLAGGKPGMHSLAIAMHPFMQLHGLLEERALDVMLEVKDKNLSAIKCANLTRAGLPRKNLTEEWARYKYLILERSPGVYS
AIRQLLKSENPTAEAFYGLLEDALACRLEPGKARNAAEHVWGYVSRNAPARESARILKDLELLGNDLTPLPRIKRKLLTL
AADNNEDYLLHSLYFYIN
>Mature_418_residues
MIRYGFACKTVGLPGAAQSSLTLSRASRDNLLSVSRNNLGALETMLRYCHRQSLALMRVSSDIIPLASHEAVHFDWQTEL
RSELESLAALAHQSGVRLSMHPGQYTVLNSPRPDVVRKAVADLAYHAAFLDALQAGPECRIILHLGGGYGDRESALQRLR
SNLAALPASILQRLALENDERIYTIEDVLAVCRDFDLPAVFDIFHHELNPPPHGDTQYWLDRAGETWNSRSGRQKIHYSQ
QLAGGKPGMHSLAIAMHPFMQLHGLLEERALDVMLEVKDKNLSAIKCANLTRAGLPRKNLTEEWARYKYLILERSPGVYS
AIRQLLKSENPTAEAFYGLLEDALACRLEPGKARNAAEHVWGYVSRNAPARESARILKDLELLGNDLTPLPRIKRKLLTL
AADNNEDYLLHSLYFYIN

Specific function: Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion [H]

COG id: COG4294

COG function: function code L; UV damage repair endonuclease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uve1/uvsE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004601
- InterPro:   IPR013022 [H]

Pfam domain/function: PF03851 UvdE [H]

EC number: NA

Molecular weight: Translated: 46817; Mature: 46817

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRYGFACKTVGLPGAAQSSLTLSRASRDNLLSVSRNNLGALETMLRYCHRQSLALMRVS
CCEECCEEEECCCCCCCCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
SDIIPLASHEAVHFDWQTELRSELESLAALAHQSGVRLSMHPGQYTVLNSPRPDVVRKAV
CCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCHHHHHHHH
ADLAYHAAFLDALQAGPECRIILHLGGGYGDRESALQRLRSNLAALPASILQRLALENDE
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RIYTIEDVLAVCRDFDLPAVFDIFHHELNPPPHGDTQYWLDRAGETWNSRSGRQKIHYSQ
CEEEHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHH
QLAGGKPGMHSLAIAMHPFMQLHGLLEERALDVMLEVKDKNLSAIKCANLTRAGLPRKNL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCHHCCCCCCCH
TEEWARYKYLILERSPGVYSAIRQLLKSENPTAEAFYGLLEDALACRLEPGKARNAAEHV
HHHHHHEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
WGYVSRNAPARESARILKDLELLGNDLTPLPRIKRKLLTLAADNNEDYLLHSLYFYIN
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEEC
>Mature Secondary Structure
MIRYGFACKTVGLPGAAQSSLTLSRASRDNLLSVSRNNLGALETMLRYCHRQSLALMRVS
CCEECCEEEECCCCCCCCCCHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHC
SDIIPLASHEAVHFDWQTELRSELESLAALAHQSGVRLSMHPGQYTVLNSPRPDVVRKAV
CCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEECCCCHHHHHHHH
ADLAYHAAFLDALQAGPECRIILHLGGGYGDRESALQRLRSNLAALPASILQRLALENDE
HHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RIYTIEDVLAVCRDFDLPAVFDIFHHELNPPPHGDTQYWLDRAGETWNSRSGRQKIHYSQ
CEEEHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCHHHHHHH
QLAGGKPGMHSLAIAMHPFMQLHGLLEERALDVMLEVKDKNLSAIKCANLTRAGLPRKNL
HHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEEECCCHHCCCCCCCH
TEEWARYKYLILERSPGVYSAIRQLLKSENPTAEAFYGLLEDALACRLEPGKARNAAEHV
HHHHHHEEEEEEECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
WGYVSRNAPARESARILKDLELLGNDLTPLPRIKRKLLTLAADNNEDYLLHSLYFYIN
HHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11792842 [H]