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The map label for this gene is hflX [H]

Identifier: 220904152

GI number: 220904152

Start: 1027950

End: 1029635

Strand: Reverse

Name: hflX [H]

Synonym: Ddes_0879

Alternate gene names: 220904152

Gene position: 1029635-1027950 (Counterclockwise)

Preceding gene: 220904153

Following gene: 220904150

Centisome position: 35.83

GC content: 61.8

Gene sequence:

>1686_bases
TTGCGCCAGGAGCATGATATTTCAAAACCAGAAGGCAATCTGCAAGGGCTGAAACCCAGCCAGCTGGCCGCCCTCAACCG
CCTGTTTAACCGCCGTTTTCCGGCGGAAGACGTGTATACGGTGGAGCAGGCGCGCGAACTGGCCCTGCTGTCACGCGCTC
TCGGGCGGCAAATAGGCCTGCTCATTGACCGCAAGGGCCGTGTACAGACGGTCATTGTGGGCAAGGCCGGCAGCATCCTG
ATACCCGAACTGCCCCGAGGCCGCAGCGGCGGCGAGCGTTTGCGCGGCCTTCGGCTGCTGCATACCCACCTGACCCCCGA
CGGCCTCAGCCAGGAAGACCTGATGGACATGCTCTTTCTGCGCCTGGATGCCGTCATTGTCCTGACTGTCAATCCTGTGG
GCGAACCGGTACAGTGGCAGGCGGCGCATCTTTTGCCCACAAACGTCAACGGGCAAGGTTATCATCTGGAGCTGCCACGC
CCGTGGGACCGCACAGCGGCCCAGATGGTGGGTACGGCCGAAGCGCTGGAAAAAGACCTCTCCCGCCGGGCCGAAAGCAG
CCATGAAGCGGAAAACAGGCCCCGCGCCCTGCTTATCTCTGTGGCAGCCCTGCCCCGCATCATGCAGGAGCGTAATCTGG
ACGAACTGGCCGAACTGGCCCGCACAGCCGGGCTTGCCATAGCCGGGCGCATGGTGCAGCGCGTCCCCCAGGTGAACCCG
CGCCTGATCATGGGCCGGGGCAAGGTGGCGGAACTGGAGGTGCTGACCCTGCAGGGTCGGGCGGACACTCTTGTTTTTGA
TGGTGAACTTTCGCCTGCGCAGCTGCATAATCTGGCAGATATTACCGAGCGCAAAGTCATTGACCGCACCCAGCTTATTC
TTGATATCTTTGCCCAGCATGCAGTAAGCCGGGCCGGAAAGCTGCAGGTTGAGCTGGCCCAGTTGCGCTATACCCAGCCG
CGACTGGTGGGCAAAAACCGCGCCATGGACCGCCTTATGGGCGGCATCGGCGGGCGCGGCCCCGGCGAAACAAAACTTGA
AACCGACCGACGCAAAATACGCGAGCGTATGGCCCGCATCCGGAAAGACCTTGAGCGCTTACGCCGCCAGCGTGCCTTCA
CCCGCGACCGCCGTTCACGCCAGGGCATTCCTCTGGCGGCGCTGGTGGGCTACACCAATGCGGGCAAATCCACCCTGCTC
AACACGCTCACCCGCTCTGAGGTCCTGGTGGAAAACAAACTTTTCGCCACGCTTGATCCCACCACACGGCGCTTGCGCTT
TCCGGCCGAGAAAGAACTTATCCTGGCGGACACCGTGGGCTTTATCCGCAATCTGCCCAAAGAGCTGATGGACGCGTTTC
GCGCCACCCTTGAGGAGCTGGAAGCCGCCCACCTGCTTTTGCATGTGGCCGACGCCTCTCACCCTGACCTGTTGCAGCAG
ATCAGCGCCGTTGAAACCATTCTGGCAGAAATGGAGCTTGACCGTATGCCCCGTCTGCTCATCCTGAACAAGTGGGACCA
GCTTGAGGCCCCGGCCAGGGCTGAACTGGCCGACGCCTTTCCCCATGCCCTGCCCGTGGCTGCCAAAACCGGCGAAGGGT
GCAAGCCCTTGCTTGAACAGCTTGAAATGCGCCTGCTGCATCAGGCCACCAACATCGTGACCGAAATATCCCCCAGTCTG
AATTAG

Upstream 100 bases:

>100_bases
ATCTGCGCCCGTAACCACCATCAGGCAGGGCGGCCCCGGGCCGCCCTGTTTTTTTCAGCCGTGGCCCGCCAGCATGCGGG
CCAGAGCGAAAAGCGCACCA

Downstream 100 bases:

>100_bases
GGAATTTTTCCCTGATATTGCTCTGGAGACTGCGCGGCAACTTCCTACATCGCCTGCCTGAACCAGCCACAACATCGCCA
GCTGCCCGAATCTGCCCAAA

Product: GTP-binding proten HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MRQEHDISKPEGNLQGLKPSQLAALNRLFNRRFPAEDVYTVEQARELALLSRALGRQIGLLIDRKGRVQTVIVGKAGSIL
IPELPRGRSGGERLRGLRLLHTHLTPDGLSQEDLMDMLFLRLDAVIVLTVNPVGEPVQWQAAHLLPTNVNGQGYHLELPR
PWDRTAAQMVGTAEALEKDLSRRAESSHEAENRPRALLISVAALPRIMQERNLDELAELARTAGLAIAGRMVQRVPQVNP
RLIMGRGKVAELEVLTLQGRADTLVFDGELSPAQLHNLADITERKVIDRTQLILDIFAQHAVSRAGKLQVELAQLRYTQP
RLVGKNRAMDRLMGGIGGRGPGETKLETDRRKIRERMARIRKDLERLRRQRAFTRDRRSRQGIPLAALVGYTNAGKSTLL
NTLTRSEVLVENKLFATLDPTTRRLRFPAEKELILADTVGFIRNLPKELMDAFRATLEELEAAHLLLHVADASHPDLLQQ
ISAVETILAEMELDRMPRLLILNKWDQLEAPARAELADAFPHALPVAAKTGEGCKPLLEQLEMRLLHQATNIVTEISPSL
N

Sequences:

>Translated_561_residues
MRQEHDISKPEGNLQGLKPSQLAALNRLFNRRFPAEDVYTVEQARELALLSRALGRQIGLLIDRKGRVQTVIVGKAGSIL
IPELPRGRSGGERLRGLRLLHTHLTPDGLSQEDLMDMLFLRLDAVIVLTVNPVGEPVQWQAAHLLPTNVNGQGYHLELPR
PWDRTAAQMVGTAEALEKDLSRRAESSHEAENRPRALLISVAALPRIMQERNLDELAELARTAGLAIAGRMVQRVPQVNP
RLIMGRGKVAELEVLTLQGRADTLVFDGELSPAQLHNLADITERKVIDRTQLILDIFAQHAVSRAGKLQVELAQLRYTQP
RLVGKNRAMDRLMGGIGGRGPGETKLETDRRKIRERMARIRKDLERLRRQRAFTRDRRSRQGIPLAALVGYTNAGKSTLL
NTLTRSEVLVENKLFATLDPTTRRLRFPAEKELILADTVGFIRNLPKELMDAFRATLEELEAAHLLLHVADASHPDLLQQ
ISAVETILAEMELDRMPRLLILNKWDQLEAPARAELADAFPHALPVAAKTGEGCKPLLEQLEMRLLHQATNIVTEISPSL
N
>Mature_561_residues
MRQEHDISKPEGNLQGLKPSQLAALNRLFNRRFPAEDVYTVEQARELALLSRALGRQIGLLIDRKGRVQTVIVGKAGSIL
IPELPRGRSGGERLRGLRLLHTHLTPDGLSQEDLMDMLFLRLDAVIVLTVNPVGEPVQWQAAHLLPTNVNGQGYHLELPR
PWDRTAAQMVGTAEALEKDLSRRAESSHEAENRPRALLISVAALPRIMQERNLDELAELARTAGLAIAGRMVQRVPQVNP
RLIMGRGKVAELEVLTLQGRADTLVFDGELSPAQLHNLADITERKVIDRTQLILDIFAQHAVSRAGKLQVELAQLRYTQP
RLVGKNRAMDRLMGGIGGRGPGETKLETDRRKIRERMARIRKDLERLRRQRAFTRDRRSRQGIPLAALVGYTNAGKSTLL
NTLTRSEVLVENKLFATLDPTTRRLRFPAEKELILADTVGFIRNLPKELMDAFRATLEELEAAHLLLHVADASHPDLLQQ
ISAVETILAEMELDRMPRLLILNKWDQLEAPARAELADAFPHALPVAAKTGEGCKPLLEQLEMRLLHQATNIVTEISPSL
N

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=238, Percent_Identity=36.1344537815126, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI310133116, Length=230, Percent_Identity=36.0869565217391, Blast_Score=129, Evalue=9e-30,
Organism=Homo sapiens, GI310124269, Length=213, Percent_Identity=37.0892018779343, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI310124267, Length=213, Percent_Identity=37.0892018779343, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI310124171, Length=213, Percent_Identity=37.0892018779343, Blast_Score=128, Evalue=2e-29,
Organism=Homo sapiens, GI310124169, Length=213, Percent_Identity=37.0892018779343, Blast_Score=128, Evalue=2e-29,
Organism=Escherichia coli, GI1790615, Length=336, Percent_Identity=45.5357142857143, Blast_Score=261, Evalue=8e-71,
Organism=Caenorhabditis elegans, GI17561038, Length=289, Percent_Identity=27.681660899654, Blast_Score=110, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24650079, Length=322, Percent_Identity=34.7826086956522, Blast_Score=134, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 62732; Mature: 62732

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQEHDISKPEGNLQGLKPSQLAALNRLFNRRFPAEDVYTVEQARELALLSRALGRQIGL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCE
LIDRKGRVQTVIVGKAGSILIPELPRGRSGGERLRGLRLLHTHLTPDGLSQEDLMDMLFL
EEECCCCEEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
RLDAVIVLTVNPVGEPVQWQAAHLLPTNVNGQGYHLELPRPWDRTAAQMVGTAEALEKDL
HHCEEEEEEECCCCCCCCCCCCEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
SRRAESSHEAENRPRALLISVAALPRIMQERNLDELAELARTAGLAIAGRMVQRVPQVNP
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RLIMGRGKVAELEVLTLQGRADTLVFDGELSPAQLHNLADITERKVIDRTQLILDIFAQH
EEEECCCCEEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSRAGKLQVELAQLRYTQPRLVGKNRAMDRLMGGIGGRGPGETKLETDRRKIRERMARI
HHHHCCCCEEEHHHHHCCCCHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
RKDLERLRRQRAFTRDRRSRQGIPLAALVGYTNAGKSTLLNTLTRSEVLVENKLFATLDP
HHHHHHHHHHHHHHHHHHHCCCCCEEHEECCCCCCHHHHHHHHHHHHHHHHCCEEEEECC
TTRRLRFPAEKELILADTVGFIRNLPKELMDAFRATLEELEAAHLLLHVADASHPDLLQQ
CHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ISAVETILAEMELDRMPRLLILNKWDQLEAPARAELADAFPHALPVAAKTGEGCKPLLEQ
HHHHHHHHHHHHHHHCCCEEEECCCHHCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LEMRLLHQATNIVTEISPSLN
HHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRQEHDISKPEGNLQGLKPSQLAALNRLFNRRFPAEDVYTVEQARELALLSRALGRQIGL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCE
LIDRKGRVQTVIVGKAGSILIPELPRGRSGGERLRGLRLLHTHLTPDGLSQEDLMDMLFL
EEECCCCEEEEEEECCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
RLDAVIVLTVNPVGEPVQWQAAHLLPTNVNGQGYHLELPRPWDRTAAQMVGTAEALEKDL
HHCEEEEEEECCCCCCCCCCCCEEEECCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHH
SRRAESSHEAENRPRALLISVAALPRIMQERNLDELAELARTAGLAIAGRMVQRVPQVNP
HHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
RLIMGRGKVAELEVLTLQGRADTLVFDGELSPAQLHNLADITERKVIDRTQLILDIFAQH
EEEECCCCEEEEEEEEECCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVSRAGKLQVELAQLRYTQPRLVGKNRAMDRLMGGIGGRGPGETKLETDRRKIRERMARI
HHHHCCCCEEEHHHHHCCCCHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
RKDLERLRRQRAFTRDRRSRQGIPLAALVGYTNAGKSTLLNTLTRSEVLVENKLFATLDP
HHHHHHHHHHHHHHHHHHHCCCCCEEHEECCCCCCHHHHHHHHHHHHHHHHCCEEEEECC
TTRRLRFPAEKELILADTVGFIRNLPKELMDAFRATLEELEAAHLLLHVADASHPDLLQQ
CHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ISAVETILAEMELDRMPRLLILNKWDQLEAPARAELADAFPHALPVAAKTGEGCKPLLEQ
HHHHHHHHHHHHHHHCCCEEEECCCHHCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LEMRLLHQATNIVTEISPSLN
HHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]