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The map label for this gene is comM [H]

Identifier: 220903564

GI number: 220903564

Start: 335396

End: 336934

Strand: Direct

Name: comM [H]

Synonym: Ddes_0283

Alternate gene names: 220903564

Gene position: 335396-336934 (Clockwise)

Preceding gene: 220903563

Following gene: 220903573

Centisome position: 11.67

GC content: 66.21

Gene sequence:

>1539_bases
GTGGTGGTCCGGCTGAACAGCGGCGGCGTTGAAGGCGTTGATGCCTATCCCGTAGAACTGGAAGTGGACTATGTGCGCCA
GGGGCTTCCGGGCTTCACCATGGTGGGCCTGGCGGAAACCGCCGTGCGCGAGGCCAAGGACCGCGTTTTTGCTGCCTTGC
GGGCGGCAAACTTCAAGCTGCCCCCGGCGCGGGTAACCGTCAATCTTGCCCCTGCATGGCGGCGCAAGAGCGGGGCCAGC
TATGACCTGCCGCTGGCAATGGGGTTGCTGGCCGCTTCCGGCGGCATTCCCGCCGAAGGTTTGCAGCGTTTTTATATGGC
CGGCGAGCTTTCGCTCGCCGGTGATCTGCGCCCGGTCAGCGGTATTCTGCCTCTGGCGCTGCTGGCGCGGCAGCGCGGCG
CGGCTGGCATTATCGTGCCGCCGGGCAACGGGGCCGAGGCTGCCGTGGTACGCGGCCTGCCTGTGTATACCCCCCGTAAT
ATTGCGCAGTGCGCCGCCTTTCTGGCAGGCGCGGAGCCTCTTGAGCCGGTAGCGGAACCGGAAGAGGCGGGCCTGCCGCC
AGCGGAACATACCCTGGACTTTGCGGAAGTCAAAGGGCAGGAGGCTGCCAAGCGTGCCCTTGAGATCGCGGCGGCCGGAG
GCCATAACGTGCTTTTGCTGGGGCCTCCGGGCAGCGGCAAGACCATGCTTGCCCAGCGCCTGCCTACCATCCTTCCTCCC
CTTGATTTTGAAGAAGCTCTGGAAGTCACCAAGATTTACAGCGTGGCAAACAAGCTGCCCGGCCACGGGGGGCTTGTGCG
CCAAAGGCCTTTTCGAGCGCCGCATCACACCATTTCGGACGTGGCCCTTGTGGGCGGCGGGGCCTGGCCCCGCCCGGGCG
AAGTGAGCCTTGCCCATCGGGGGGTGCTTTTTCTTGATGAGCTGCCTGAATTTCAGAAGAGCGCGCTGGAATCACTGCGC
CAGCCTCTGGAGGGCGGCACGGTGCATATAGCGCGTGCTTCGCACAGCGTGGTTTTTCCCGCTGCCTGCATGCTTGTGGC
GGCCATGAATCCTTGCCCCTGCGGCTATTACGGCGACCCGACGCATGATTGCGTTTGCCGCCCGGACCAGCGGGCGCGGT
ATCAGGCCAGAATATCCGGCCCCATGCTGGACCGTATTGATGTGCATGTGGAGGTTCCCGCCGTGCCCTATGCTGATTTG
CGCCAGAGCAGGGCCGGGGCCGGTTCGGCGGCCATGCGGGAACGGGTGCTGGCTGCCCGGGCCGTGCAGAAGCGCCGTTA
TGGTGCGGGCGGGCCGCGCTGCAATGCGGAACTTTCCGGCGCGCTGCTTGACGCCCACTGCGGCCTTGACGCCCCGGGGC
ATGACCTTATGGAGGCGGCGGTGAACCGCCTTGCCCTGTCGGCACGCGCCTGTGCGCGGGTGTTGCGCATGGCGCGCACC
ATTGCCGATCTGGCTGGCGCAAAAAGCATTGATGCCGCGCACCTTGCCGAGGCCGTATCCCTGCGGGTTCTGGACCGGGG
GCAGGGCGGCATGGCCTGA

Upstream 100 bases:

>100_bases
ATCTACTGGTCCTGGGGCGGGCTTGACGACATGCGCTGGAACCGCATGGGCAAAAAAGTGGAATAGCCGCCCTGCGGCTC
AAGCGTGGCAAGGAGGCCCT

Downstream 100 bases:

>100_bases
GCAGGCCGGTTTTTCGTCCGCCTGGCCTGCGTTGGTCCCTGTTGCGTTTTACCCGCCGGGCTTCCGTTTTGATCTGGCCT
GAATTCCGGTCCGGCTCACG

Product: Mg chelatase, subunit ChlI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MVVRLNSGGVEGVDAYPVELEVDYVRQGLPGFTMVGLAETAVREAKDRVFAALRAANFKLPPARVTVNLAPAWRRKSGAS
YDLPLAMGLLAASGGIPAEGLQRFYMAGELSLAGDLRPVSGILPLALLARQRGAAGIIVPPGNGAEAAVVRGLPVYTPRN
IAQCAAFLAGAEPLEPVAEPEEAGLPPAEHTLDFAEVKGQEAAKRALEIAAAGGHNVLLLGPPGSGKTMLAQRLPTILPP
LDFEEALEVTKIYSVANKLPGHGGLVRQRPFRAPHHTISDVALVGGGAWPRPGEVSLAHRGVLFLDELPEFQKSALESLR
QPLEGGTVHIARASHSVVFPAACMLVAAMNPCPCGYYGDPTHDCVCRPDQRARYQARISGPMLDRIDVHVEVPAVPYADL
RQSRAGAGSAAMRERVLAARAVQKRRYGAGGPRCNAELSGALLDAHCGLDAPGHDLMEAAVNRLALSARACARVLRMART
IADLAGAKSIDAAHLAEAVSLRVLDRGQGGMA

Sequences:

>Translated_512_residues
MVVRLNSGGVEGVDAYPVELEVDYVRQGLPGFTMVGLAETAVREAKDRVFAALRAANFKLPPARVTVNLAPAWRRKSGAS
YDLPLAMGLLAASGGIPAEGLQRFYMAGELSLAGDLRPVSGILPLALLARQRGAAGIIVPPGNGAEAAVVRGLPVYTPRN
IAQCAAFLAGAEPLEPVAEPEEAGLPPAEHTLDFAEVKGQEAAKRALEIAAAGGHNVLLLGPPGSGKTMLAQRLPTILPP
LDFEEALEVTKIYSVANKLPGHGGLVRQRPFRAPHHTISDVALVGGGAWPRPGEVSLAHRGVLFLDELPEFQKSALESLR
QPLEGGTVHIARASHSVVFPAACMLVAAMNPCPCGYYGDPTHDCVCRPDQRARYQARISGPMLDRIDVHVEVPAVPYADL
RQSRAGAGSAAMRERVLAARAVQKRRYGAGGPRCNAELSGALLDAHCGLDAPGHDLMEAAVNRLALSARACARVLRMART
IADLAGAKSIDAAHLAEAVSLRVLDRGQGGMA
>Mature_512_residues
MVVRLNSGGVEGVDAYPVELEVDYVRQGLPGFTMVGLAETAVREAKDRVFAALRAANFKLPPARVTVNLAPAWRRKSGAS
YDLPLAMGLLAASGGIPAEGLQRFYMAGELSLAGDLRPVSGILPLALLARQRGAAGIIVPPGNGAEAAVVRGLPVYTPRN
IAQCAAFLAGAEPLEPVAEPEEAGLPPAEHTLDFAEVKGQEAAKRALEIAAAGGHNVLLLGPPGSGKTMLAQRLPTILPP
LDFEEALEVTKIYSVANKLPGHGGLVRQRPFRAPHHTISDVALVGGGAWPRPGEVSLAHRGVLFLDELPEFQKSALESLR
QPLEGGTVHIARASHSVVFPAACMLVAAMNPCPCGYYGDPTHDCVCRPDQRARYQARISGPMLDRIDVHVEVPAVPYADL
RQSRAGAGSAAMRERVLAARAVQKRRYGAGGPRCNAELSGALLDAHCGLDAPGHDLMEAAVNRLALSARACARVLRMART
IADLAGAKSIDAAHLAEAVSLRVLDRGQGGMA

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=496, Percent_Identity=44.9596774193548, Blast_Score=384, Evalue=1e-108,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 53801; Mature: 53801

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVRLNSGGVEGVDAYPVELEVDYVRQGLPGFTMVGLAETAVREAKDRVFAALRAANFKL
CEEEECCCCCCCCCCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PPARVTVNLAPAWRRKSGASYDLPLAMGLLAASGGIPAEGLQRFYMAGELSLAGDLRPVS
CCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCEEECCCCCCHH
GILPLALLARQRGAAGIIVPPGNGAEAAVVRGLPVYTPRNIAQCAAFLAGAEPLEPVAEP
HHHHHHHHHHCCCCCEEEECCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
EEAGLPPAEHTLDFAEVKGQEAAKRALEIAAAGGHNVLLLGPPGSGKTMLAQRLPTILPP
HHCCCCCHHHCCHHHHHCCHHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHCHHHCCC
LDFEEALEVTKIYSVANKLPGHGGLVRQRPFRAPHHTISDVALVGGGAWPRPGEVSLAHR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEECCCCCCCCCCEEHHHC
GVLFLDELPEFQKSALESLRQPLEGGTVHIARASHSVVFPAACMLVAAMNPCPCGYYGDP
CEEEHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCC
THDCVCRPDQRARYQARISGPMLDRIDVHVEVPAVPYADLRQSRAGAGSAAMRERVLAAR
CCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHH
AVQKRRYGAGGPRCNAELSGALLDAHCGLDAPGHDLMEAAVNRLALSARACARVLRMART
HHHHHHCCCCCCCCCCHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IADLAGAKSIDAAHLAEAVSLRVLDRGQGGMA
HHHHHCCCCCCHHHHHHHHHHHEEECCCCCCC
>Mature Secondary Structure
MVVRLNSGGVEGVDAYPVELEVDYVRQGLPGFTMVGLAETAVREAKDRVFAALRAANFKL
CEEEECCCCCCCCCCCEEEEEHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
PPARVTVNLAPAWRRKSGASYDLPLAMGLLAASGGIPAEGLQRFYMAGELSLAGDLRPVS
CCCEEEEEECCHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHCCEEECCCCCCHH
GILPLALLARQRGAAGIIVPPGNGAEAAVVRGLPVYTPRNIAQCAAFLAGAEPLEPVAEP
HHHHHHHHHHCCCCCEEEECCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
EEAGLPPAEHTLDFAEVKGQEAAKRALEIAAAGGHNVLLLGPPGSGKTMLAQRLPTILPP
HHCCCCCHHHCCHHHHHCCHHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHCHHHCCC
LDFEEALEVTKIYSVANKLPGHGGLVRQRPFRAPHHTISDVALVGGGAWPRPGEVSLAHR
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHEEEECCCCCCCCCCEEHHHC
GVLFLDELPEFQKSALESLRQPLEGGTVHIARASHSVVFPAACMLVAAMNPCPCGYYGDP
CEEEHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCCCCCCCCCCCC
THDCVCRPDQRARYQARISGPMLDRIDVHVEVPAVPYADLRQSRAGAGSAAMRERVLAAR
CCCCCCCCCHHHHHHHHCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHH
AVQKRRYGAGGPRCNAELSGALLDAHCGLDAPGHDLMEAAVNRLALSARACARVLRMART
HHHHHHCCCCCCCCCCHHCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IADLAGAKSIDAAHLAEAVSLRVLDRGQGGMA
HHHHHCCCCCCHHHHHHHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]