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The map label for this gene is surE

Identifier: 220903416

GI number: 220903416

Start: 166710

End: 167483

Strand: Direct

Name: surE

Synonym: Ddes_0130

Alternate gene names: 220903416

Gene position: 166710-167483 (Clockwise)

Preceding gene: 220903409

Following gene: 220903417

Centisome position: 5.8

GC content: 63.57

Gene sequence:

>774_bases
ATGAACGTTCTCCTGACCAATGACGACGGCATCCGGGCCAAGGGGCTGCGCGCCCTGTACGCGGCCCTGCGCGAGGCCGG
TCATACGGTATATGTGGTGGCCCCCATGAGCCAGCAGTCCGGCGTGGGGCATTCGCTCACGGTTTTCGAGCCTGTACGGG
CCACAGTGATTGAAGAGCCGGACTTTACTGGCACGGGCGTTTACGGAACCCCCACAGACTGCGTGAAGCTGGCCCTGGGG
CGGCTGCTGCCCCACAAGCCCGACCTTGTCATGTCCGGCATCAATGCCGGGGCCAACGTGGGGCCGGACATCCTGTATTC
CGGCACAGTGGGCGCGGCTACCGAGGCCGCCCACGAGGAACTGCCGAGCATGGCCGTCTCGTTTGACAGCTTCAGCCACA
ATACCGCTCCGGATATGGACCTTATGCCCCAGGCACGACATGCCGTGAACCTGGCCGAGCGTATGAACTGGTCTGCCGTG
GGCCGCCGCCGGGTGATCAATATCAACTATCCCGCCTGCCCCCTGGACGAGGCCCAGGATCTGCGAGTCTGCCCCCAGAC
CAGCGCCGTGTGGAAAAACGTCTATATCGAGCGTGAAGACCCGCGCGGCGCGCCCTACTGGTGGCTTGAGGGCGAAATTC
CCCCGGCAAGCATCGAGCCGGGGTCGGACAAGGACCTGCTCAACCGCGGGCATATCACCCTCACGCCTCTGTGCTTTGAT
TTTACCGACCATGAGGGACTGACCGCGCTCAAGTGCATGAAGCTTCAGGGCTGA

Upstream 100 bases:

>100_bases
CTGGCCAGGAGCGCCTGACGCCCGTGCGTTTTGAGCGCCGCCGCAAGGGCGGCTCATAGCGAAGCTTTTTCGAATTTCCC
TTCTTTCCGAGGTATTGTCA

Downstream 100 bases:

>100_bases
TGTGTCTGAAGCGGCTGTTGCCGCGCCTTTTGCCGCCTGCCGGGCATGATGCCAGAGCGCGGCGACAGGCTGAAAATACC
GTTCTGTTGTGCCGGAGACG

Product: stationary-phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MNVLLTNDDGIRAKGLRALYAALREAGHTVYVVAPMSQQSGVGHSLTVFEPVRATVIEEPDFTGTGVYGTPTDCVKLALG
RLLPHKPDLVMSGINAGANVGPDILYSGTVGAATEAAHEELPSMAVSFDSFSHNTAPDMDLMPQARHAVNLAERMNWSAV
GRRRVININYPACPLDEAQDLRVCPQTSAVWKNVYIEREDPRGAPYWWLEGEIPPASIEPGSDKDLLNRGHITLTPLCFD
FTDHEGLTALKCMKLQG

Sequences:

>Translated_257_residues
MNVLLTNDDGIRAKGLRALYAALREAGHTVYVVAPMSQQSGVGHSLTVFEPVRATVIEEPDFTGTGVYGTPTDCVKLALG
RLLPHKPDLVMSGINAGANVGPDILYSGTVGAATEAAHEELPSMAVSFDSFSHNTAPDMDLMPQARHAVNLAERMNWSAV
GRRRVININYPACPLDEAQDLRVCPQTSAVWKNVYIEREDPRGAPYWWLEGEIPPASIEPGSDKDLLNRGHITLTPLCFD
FTDHEGLTALKCMKLQG
>Mature_257_residues
MNVLLTNDDGIRAKGLRALYAALREAGHTVYVVAPMSQQSGVGHSLTVFEPVRATVIEEPDFTGTGVYGTPTDCVKLALG
RLLPHKPDLVMSGINAGANVGPDILYSGTVGAATEAAHEELPSMAVSFDSFSHNTAPDMDLMPQARHAVNLAERMNWSAV
GRRRVININYPACPLDEAQDLRVCPQTSAVWKNVYIEREDPRGAPYWWLEGEIPPASIEPGSDKDLLNRGHITLTPLCFD
FTDHEGLTALKCMKLQG

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=246, Percent_Identity=37.3983739837398, Blast_Score=150, Evalue=8e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_DESDA (B8J2G2)

Other databases:

- EMBL:   CP001358
- RefSeq:   YP_002478728.1
- ProteinModelPortal:   B8J2G2
- GeneID:   7283784
- GenomeReviews:   CP001358_GR
- KEGG:   dds:Ddes_0130
- HOGENOM:   HBG600532
- ProtClustDB:   CLSK705613
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 27921; Mature: 27921

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVLLTNDDGIRAKGLRALYAALREAGHTVYVVAPMSQQSGVGHSLTVFEPVRATVIEEP
CEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEECCCEEEEECCC
DFTGTGVYGTPTDCVKLALGRLLPHKPDLVMSGINAGANVGPDILYSGTVGAATEAAHEE
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEECCCCCCHHHHHHHH
LPSMAVSFDSFSHNTAPDMDLMPQARHAVNLAERMNWSAVGRRRVININYPACPLDEAQD
HHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCCCCCCC
LRVCPQTSAVWKNVYIEREDPRGAPYWWLEGEIPPASIEPGSDKDLLNRGHITLTPLCFD
CEECCCHHHHHHEEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCEEEEEEEEE
FTDHEGLTALKCMKLQG
CCCCCCCCEEEEEECCC
>Mature Secondary Structure
MNVLLTNDDGIRAKGLRALYAALREAGHTVYVVAPMSQQSGVGHSLTVFEPVRATVIEEP
CEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEECCCEEEEECCC
DFTGTGVYGTPTDCVKLALGRLLPHKPDLVMSGINAGANVGPDILYSGTVGAATEAAHEE
CCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCEEECCCCCCHHHHHHHH
LPSMAVSFDSFSHNTAPDMDLMPQARHAVNLAERMNWSAVGRRRVININYPACPLDEAQD
HHHHEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCCCCCCC
LRVCPQTSAVWKNVYIEREDPRGAPYWWLEGEIPPASIEPGSDKDLLNRGHITLTPLCFD
CEECCCHHHHHHEEEEECCCCCCCCEEEECCCCCCCCCCCCCCHHHHCCCCEEEEEEEEE
FTDHEGLTALKCMKLQG
CCCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA