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The map label for this gene is grdD [H]

Identifier: 220903402

GI number: 220903402

Start: 150386

End: 151552

Strand: Direct

Name: grdD [H]

Synonym: Ddes_0116

Alternate gene names: 220903402

Gene position: 150386-151552 (Clockwise)

Preceding gene: 220903401

Following gene: 220903403

Centisome position: 5.23

GC content: 64.7

Gene sequence:

>1167_bases
ATGGCTAGTCAAAATGACAAGCGCGCCATCCTCGGCAAGGCTCTTGAAGACCTGGTGACGCGGGCGCGCAGCGGGCGCGA
GCCGTGCCGCATAGGGCTTATGGCCGCCGGAGGCGAGCATTCGGATATGGAGTTCATCACGGCTGCGGCTGCTGCCATGA
AGGAAGACGCCGCCCTGACCGTGGTGGGGGTCGGCCCGCGTCCTGCCGGGCTGCTGCCCGCTGGTATGGATTGGATCGAA
ACCGGCTGCGAGGGCGGCGAACTGGCAGCAGGTATGGAAAAGGCCCTGGACAGCGGCCATATCCAGGGGGCTGTGGCCCT
GCACTATCCCTTCCCGCTGGGCGTGAGCACCGTAGGCCGCATCCTTACGCCTGCTCTGGGCAGGGCCATGTTTGTGGCCT
GCACCACGGGCATGAGCGCTGCCAAAAGGCAGCAGGCCCTGCTGCGCAATGCGGTGCTGGGCATCGCCGTGGCAAAAGCC
TCGGGGCTGGCCGCGCCCGCCGTGGGCGTGCTCAATGTGGATGCGGCTCCCCAGGTCTTGCGCGCCCTGAACCGCATGGC
GGAAAAGGGCTATGCCCTGAACCTCGGGCAGAGCGTCAGGGGTGACGGCGGCTCGCTGCTGCGTGGCAACGACCTTTTGC
GCGGCGCTGTTGATGTGTGCGTTACGGATACACTGACGGGCAATGTGCTCATGAAGCTCTTTGGCGCATTCACTTCGGGC
GGCGCTTACGAAACCACCGGCTGGGGCTACGGGCCTTCCGTGGGCGAAGGCTGGAACAAGGTTGTAAGCATCATCTCCCG
TGCATCGGGTTCCCCGGTTATCGCCAATGCCCTTGCCTATACGGCGGCGGCCGTGCGTGGCCGGCTGCCTGTCCTGGTAG
CTGAAGAATTGCGCATGGCGCGCGCTGCCGGACTGGATGATGAGCTGGCCGCCTTTGAAAAGAGCGATGCCGCCCCGGCC
GTTCAGGTGTCGCCGCCCCCGGTTGAACCCACTGATGAGGAAATACACGGCATTGACGTGCTGGACCTGGAGCAGGCAGT
GCGCTGCCTGTGGAAGGAAAAAATATATGCCGAGGCCGCCATGGGCTGCACCGGCCCCGTGGTGAAGCTGGCTTCGGCCC
GGCTTGAGGCTGCGCGTAAGATATTGGCGGATGCCGGTTACATTTGA

Upstream 100 bases:

>100_bases
GCGGCGCAGGATGTCAGCCAGGCGGATGTGACGGAAATGCTGCTCGGCACTCTGGGCGATCTGGCGGCCAATCTGCAAAA
GGGCCGGTAGAGGAGGGGCT

Downstream 100 bases:

>100_bases
TCCTCCGGCAGGCGGGCCGCCCTGAGTCGGAGCCGTCCGGCACAGGCCCCGGCCCGCCTTTATCTATAAAGTTTCAACCA
TCCGCAAGCAAAGCGAGGTG

Product: glycine reductase

Products: NA

Alternate protein names: Protein PC alpha [H]

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MASQNDKRAILGKALEDLVTRARSGREPCRIGLMAAGGEHSDMEFITAAAAAMKEDAALTVVGVGPRPAGLLPAGMDWIE
TGCEGGELAAGMEKALDSGHIQGAVALHYPFPLGVSTVGRILTPALGRAMFVACTTGMSAAKRQQALLRNAVLGIAVAKA
SGLAAPAVGVLNVDAAPQVLRALNRMAEKGYALNLGQSVRGDGGSLLRGNDLLRGAVDVCVTDTLTGNVLMKLFGAFTSG
GAYETTGWGYGPSVGEGWNKVVSIISRASGSPVIANALAYTAAAVRGRLPVLVAEELRMARAAGLDDELAAFEKSDAAPA
VQVSPPPVEPTDEEIHGIDVLDLEQAVRCLWKEKIYAEAAMGCTGPVVKLASARLEAARKILADAGYI

Sequences:

>Translated_388_residues
MASQNDKRAILGKALEDLVTRARSGREPCRIGLMAAGGEHSDMEFITAAAAAMKEDAALTVVGVGPRPAGLLPAGMDWIE
TGCEGGELAAGMEKALDSGHIQGAVALHYPFPLGVSTVGRILTPALGRAMFVACTTGMSAAKRQQALLRNAVLGIAVAKA
SGLAAPAVGVLNVDAAPQVLRALNRMAEKGYALNLGQSVRGDGGSLLRGNDLLRGAVDVCVTDTLTGNVLMKLFGAFTSG
GAYETTGWGYGPSVGEGWNKVVSIISRASGSPVIANALAYTAAAVRGRLPVLVAEELRMARAAGLDDELAAFEKSDAAPA
VQVSPPPVEPTDEEIHGIDVLDLEQAVRCLWKEKIYAEAAMGCTGPVVKLASARLEAARKILADAGYI
>Mature_387_residues
ASQNDKRAILGKALEDLVTRARSGREPCRIGLMAAGGEHSDMEFITAAAAAMKEDAALTVVGVGPRPAGLLPAGMDWIET
GCEGGELAAGMEKALDSGHIQGAVALHYPFPLGVSTVGRILTPALGRAMFVACTTGMSAAKRQQALLRNAVLGIAVAKAS
GLAAPAVGVLNVDAAPQVLRALNRMAEKGYALNLGQSVRGDGGSLLRGNDLLRGAVDVCVTDTLTGNVLMKLFGAFTSGG
AYETTGWGYGPSVGEGWNKVVSIISRASGSPVIANALAYTAAAVRGRLPVLVAEELRMARAAGLDDELAAFEKSDAAPAV
QVSPPPVEPTDEEIHGIDVLDLEQAVRCLWKEKIYAEAAMGCTGPVVKLASARLEAARKILADAGYI

Specific function: In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a c

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003664
- InterPro:   IPR012116 [H]

Pfam domain/function: PF02504 FA_synthesis [H]

EC number: =1.21.4.2; =1.21.4.3; =1.21.4.4 [H]

Molecular weight: Translated: 39982; Mature: 39851

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASQNDKRAILGKALEDLVTRARSGREPCRIGLMAAGGEHSDMEFITAAAAAMKEDAALT
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEE
VVGVGPRPAGLLPAGMDWIETGCEGGELAAGMEKALDSGHIQGAVALHYPFPLGVSTVGR
EEECCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
ILTPALGRAMFVACTTGMSAAKRQQALLRNAVLGIAVAKASGLAAPAVGVLNVDAAPQVL
HHHHHHHHHEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHH
RALNRMAEKGYALNLGQSVRGDGGSLLRGNDLLRGAVDVCVTDTLTGNVLMKLFGAFTSG
HHHHHHHHCCCEEECCCCCCCCCCCEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
GAYETTGWGYGPSVGEGWNKVVSIISRASGSPVIANALAYTAAAVRGRLPVLVAEELRMA
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RAAGLDDELAAFEKSDAAPAVQVSPPPVEPTDEEIHGIDVLDLEQAVRCLWKEKIYAEAA
HHCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHH
MGCTGPVVKLASARLEAARKILADAGYI
CCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASQNDKRAILGKALEDLVTRARSGREPCRIGLMAAGGEHSDMEFITAAAAAMKEDAALT
CCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEE
VVGVGPRPAGLLPAGMDWIETGCEGGELAAGMEKALDSGHIQGAVALHYPFPLGVSTVGR
EEECCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHH
ILTPALGRAMFVACTTGMSAAKRQQALLRNAVLGIAVAKASGLAAPAVGVLNVDAAPQVL
HHHHHHHHHEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHH
RALNRMAEKGYALNLGQSVRGDGGSLLRGNDLLRGAVDVCVTDTLTGNVLMKLFGAFTSG
HHHHHHHHCCCEEECCCCCCCCCCCEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
GAYETTGWGYGPSVGEGWNKVVSIISRASGSPVIANALAYTAAAVRGRLPVLVAEELRMA
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
RAAGLDDELAAFEKSDAAPAVQVSPPPVEPTDEEIHGIDVLDLEQAVRCLWKEKIYAEAA
HHCCCCHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHH
MGCTGPVVKLASARLEAARKILADAGYI
CCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11737196; 1587286 [H]