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The map label for this gene is trxB [H]

Identifier: 220903400

GI number: 220903400

Start: 147790

End: 148704

Strand: Direct

Name: trxB [H]

Synonym: Ddes_0114

Alternate gene names: 220903400

Gene position: 147790-148704 (Clockwise)

Preceding gene: 220903399

Following gene: 220903401

Centisome position: 5.14

GC content: 56.72

Gene sequence:

>915_bases
ATGGAAAAGCGTGAACTGGTCATCATCGGCGCAGGTCCGGCGGGCCTTTCTGCCGCCATTTACGGCAAGCGCGCCGGTCT
TGATACACTTGTTCTGGAAAAAGGCCGTCCAGGCGGCCAGATACTGACCACCAGCAGGGTGGAAAACTATCCCGGCATCA
TTGACGGCACGGGAACAGGGCTGGCCGATGCGTTTCGTGCGCATGCGGAATTTTTCAAGGCGGAGTTCCGTTCGGTTTCT
GTGCAAAAGCTCGAGGTGCGCGGCAACGAAAAGATCATCACCCTCAAGGACGGTACGGAAATCGCCGCCGGGGCCGTGAT
TGTCGCCAGCGGAGCCTACTTTCGCAAACAGGGCTGCCCCGGCGAAAAAAAATACACGGGCATGGGCGTTTCCTATTGCG
CCGTGTGCGATGCGGCTTTTTTTGAAGATCTTGAAGTGGCTGTCATCGGCGGTGGCAATACCGCTGTGGAAGAAGCCTGC
TACCTTACGGGCTTTGCCTCCAGGGTATACCTCATCCATCGCCGTGACGAGTTTCGTGCCGACAGGCTTGTGGTAGAGCA
CGCCCTGGCAAATCCCAAGATTGTACCTGTGATGGACAGCGTGCTGGAATCCATTGAAGGTAGCGACATGGTTGAAAAAA
TCATGGTGCGCAACGTGAAAACCAATAAAATGCGCCAGATCGATCTGAGCGGCGTGTTCATTTTCATCGGCACATTGCCC
AATGCGGAATTTCTGCATGGCCTGCTGCAGACGGATGCCGGTGGCTGGATAATCACCGATGACAAGCTGCAAACCTCTGT
TCCCGGTATTTTTGCAGCCGGCGACGTACGCAACACCTCGTTGCGGCAGGTCGTCACAGCGGCCGGTGACGGCGCACGGG
CCGCCATGGCGGCCTATGCCTACCTTCAACACTAG

Upstream 100 bases:

>100_bases
ATGCCGGGCCTTGCCGGAGCCGGAAACCAAAGGAACACACAGCAGACTTCGCGGCCGGATAACGCCACGGCGTACGCATA
CGGCCCTTCAAGGAGTTTTT

Downstream 100 bases:

>100_bases
AGCGTCACGCAACGGAGCGGGTGCATGCGCCGCAAGGCCTGCGCCTTGCCGTGGAGCAGACACCGGCAGGCCCCCCTGCC
GTTAAGCAACTCTTTCAAGT

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MEKRELVIIGAGPAGLSAAIYGKRAGLDTLVLEKGRPGGQILTTSRVENYPGIIDGTGTGLADAFRAHAEFFKAEFRSVS
VQKLEVRGNEKIITLKDGTEIAAGAVIVASGAYFRKQGCPGEKKYTGMGVSYCAVCDAAFFEDLEVAVIGGGNTAVEEAC
YLTGFASRVYLIHRRDEFRADRLVVEHALANPKIVPVMDSVLESIEGSDMVEKIMVRNVKTNKMRQIDLSGVFIFIGTLP
NAEFLHGLLQTDAGGWIITDDKLQTSVPGIFAAGDVRNTSLRQVVTAAGDGARAAMAAYAYLQH

Sequences:

>Translated_304_residues
MEKRELVIIGAGPAGLSAAIYGKRAGLDTLVLEKGRPGGQILTTSRVENYPGIIDGTGTGLADAFRAHAEFFKAEFRSVS
VQKLEVRGNEKIITLKDGTEIAAGAVIVASGAYFRKQGCPGEKKYTGMGVSYCAVCDAAFFEDLEVAVIGGGNTAVEEAC
YLTGFASRVYLIHRRDEFRADRLVVEHALANPKIVPVMDSVLESIEGSDMVEKIMVRNVKTNKMRQIDLSGVFIFIGTLP
NAEFLHGLLQTDAGGWIITDDKLQTSVPGIFAAGDVRNTSLRQVVTAAGDGARAAMAAYAYLQH
>Mature_304_residues
MEKRELVIIGAGPAGLSAAIYGKRAGLDTLVLEKGRPGGQILTTSRVENYPGIIDGTGTGLADAFRAHAEFFKAEFRSVS
VQKLEVRGNEKIITLKDGTEIAAGAVIVASGAYFRKQGCPGEKKYTGMGVSYCAVCDAAFFEDLEVAVIGGGNTAVEEAC
YLTGFASRVYLIHRRDEFRADRLVVEHALANPKIVPVMDSVLESIEGSDMVEKIMVRNVKTNKMRQIDLSGVFIFIGTLP
NAEFLHGLLQTDAGGWIITDDKLQTSVPGIFAAGDVRNTSLRQVVTAAGDGARAAMAAYAYLQH

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=309, Percent_Identity=39.8058252427184, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI87081763, Length=304, Percent_Identity=36.8421052631579, Blast_Score=166, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6320560, Length=315, Percent_Identity=37.1428571428571, Blast_Score=192, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6321898, Length=315, Percent_Identity=35.2380952380952, Blast_Score=181, Evalue=2e-46,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 32552; Mature: 32552

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKRELVIIGAGPAGLSAAIYGKRAGLDTLVLEKGRPGGQILTTSRVENYPGIIDGTGTG
CCCCEEEEEECCCCCCEEEEECCCCCCCEEEEECCCCCCEEEEECCCCCCCCEEECCCCC
LADAFRAHAEFFKAEFRSVSVQKLEVRGNEKIITLKDGTEIAAGAVIVASGAYFRKQGCP
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCEEEEECCCHHHHCCCC
GEKKYTGMGVSYCAVCDAAFFEDLEVAVIGGGNTAVEEACYLTGFASRVYLIHRRDEFRA
CCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHEECCCEEEEEEECCHHHH
DRLVVEHALANPKIVPVMDSVLESIEGSDMVEKIMVRNVKTNKMRQIDLSGVFIFIGTLP
HHHHHHHHHCCCCEEHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCC
NAEFLHGLLQTDAGGWIITDDKLQTSVPGIFAAGDVRNTSLRQVVTAAGDGARAAMAAYA
CHHHHHHHHHCCCCCEEEECCCHHCCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHHH
YLQH
HHCC
>Mature Secondary Structure
MEKRELVIIGAGPAGLSAAIYGKRAGLDTLVLEKGRPGGQILTTSRVENYPGIIDGTGTG
CCCCEEEEEECCCCCCEEEEECCCCCCCEEEEECCCCCCEEEEECCCCCCCCEEECCCCC
LADAFRAHAEFFKAEFRSVSVQKLEVRGNEKIITLKDGTEIAAGAVIVASGAYFRKQGCP
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCCCCCCCEEEEECCCHHHHCCCC
GEKKYTGMGVSYCAVCDAAFFEDLEVAVIGGGNTAVEEACYLTGFASRVYLIHRRDEFRA
CCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHEECCCEEEEEEECCHHHH
DRLVVEHALANPKIVPVMDSVLESIEGSDMVEKIMVRNVKTNKMRQIDLSGVFIFIGTLP
HHHHHHHHHCCCCEEHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEECCEEEEEEECCC
NAEFLHGLLQTDAGGWIITDDKLQTSVPGIFAAGDVRNTSLRQVVTAAGDGARAAMAAYA
CHHHHHHHHHCCCCCEEEECCCHHCCCCCEEEECCCCCHHHHHHHHHCCCCHHHHHHHHH
YLQH
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA