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The map label for this gene is grdB [H]

Identifier: 220903399

GI number: 220903399

Start: 146239

End: 147543

Strand: Direct

Name: grdB [H]

Synonym: Ddes_0113

Alternate gene names: 220903399

Gene position: 146239-147543 (Clockwise)

Preceding gene: 220903398

Following gene: 220903400

Centisome position: 5.09

GC content: 60.84

Gene sequence:

>1305_bases
ATGGCATATAAGCTTGTGCATTATATAAATCAGTTTTTTGCCGGTATCGGCGGTGAAGACAAGGCCGACGTCAGCCCCGA
AGTGCGCGAGGGCATCGTGGGTCCCGGCATGGCCTTCAAGGCCGCTCTGGGCGATCAGGCCGAAATCGTGGCTACCTTTA
TCTGCGGCGATAACTATTGCGCCAACAATCTCGACGCCGTGGCCGCCAGGATGGTGGAAACCGTAAAGAGCTTCGGGGCT
GACGGCCTCATAGCCGGGCCTGCCTTTAACGCGGGCCGCTACGGCACTGCCTGCGGCGCGGTGTGCGCTGCAGTCAACAA
GCAGCTCGGCCTGCCCGTGGTAAGCGGCATGTACCGTGAAAGCCCCGGTGTGGACCTGTACCGCAAGGAAGTAACCATTG
TGGAAACGGCCGACAGCGCCCGCGGCATGGGCAAGGCCGTACCTGCCATGGCCGCTGTGGTGCTTAAGCTGCTGCGCGGC
GAAGAAATCGCCGACCCGGCGGCCGAAGGCGTTTTTCCCAAGGGCATCCGCAAGAACATGTTTTATGACGAACCCGGGGC
CGAGCGCGCTGTACGCATGCTCATCAAGAAGGTCGGGGGCGAAGAGTTCAAGACCGAATACGCCATGCCCATATTCGACC
GTGTGGAGCCGCGCCCGGCCATTGCCGACATGAGCAGGGCCACCATCGCCGTGGTTACCTCGGGCGGCATCGTGCCTGAA
GGTAACCCCGACCATATCGCCGCCTCGTCGGCCCAGAACTTCGGCGCCTACAGCATCGAGGGCGTTACCGACCTTGAAAA
GGGCAGGTACCTCACCGCTCACGGCGGCTATGACCAGACCTACGCCAATCAGGATCCCGATCGCGTACTGCCCATAGACG
TGCTGCGCGACCTGGAAAAAGAAGGCAGGATCGGCAAGCTCTACAACGTGTTCTACACCACTGTGGGCAACGGTACATCC
GTAGCCAACTCGCGCAAGTTTGGCACAGAAATCGGCTCGCAGCTCAAGGCCGCACATGTGGACGGGGTCATACTCACATC
CACCTGAGGCACGTGCACGCGTTGCGGTGCAACGCTCGCCAAGGCCATTGAAGAAGCTGCCGATGTGCCCGTGGTCCACA
TGTGCACCATCGTGCCGATTTCCCTGAGTATCGGGGCCAACCGTATTGTGCCCACTGTGTCCATTCCTCACCCCCTGGGC
AATCCCGAACTTTCTGCCGCTGAAGAAAAGCATCTGCGACGCGAGCTGGTGCTCAAGGCCCTTCAGGCCCTTTCCACCGG
GGTAGACGGGCAGACGGTGTTCTAG

Upstream 100 bases:

>100_bases
GAGTTGCAGGCCATACTCGGCGCCACGAACGAACTGGGCTTTAACCGCATTGGCGGCCGCACCCTGTAGGGGCGTCCGGC
TCAAGGAGCAGGAGACTATC

Downstream 100 bases:

>100_bases
CCCGCACGGGTTTTCGTTCTCCGGCTTCCGGCAGCGTCGCAAAAGCGTCCGGAAGCCGGGATCAGACCGGCGGCCAAACG
GCGGGCAGGCGGCTCTATTC

Product: selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family

Products: NA

Alternate protein names: Selenoprotein PB gamma [H]

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MAYKLVHYINQFFAGIGGEDKADVSPEVREGIVGPGMAFKAALGDQAEIVATFICGDNYCANNLDAVAARMVETVKSFGA
DGLIAGPAFNAGRYGTACGAVCAAVNKQLGLPVVSGMYRESPGVDLYRKEVTIVETADSARGMGKAVPAMAAVVLKLLRG
EEIADPAAEGVFPKGIRKNMFYDEPGAERAVRMLIKKVGGEEFKTEYAMPIFDRVEPRPAIADMSRATIAVVTSGGIVPE
GNPDHIAASSAQNFGAYSIEGVTDLEKGRYLTAHGGYDQTYANQDPDRVLPIDVLRDLEKEGRIGKLYNVFYTTVGNGTS
VANSRKFGTEIGSQLKAAHVDGVILTSTUGTCTRCGATLAKAIEEAADVPVVHMCTIVPISLSIGANRIVPTVSIPHPLG
NPELSAAEEKHLRRELVLKALQALSTGVDGQTVF

Sequences:

>Translated_434_residues
MAYKLVHYINQFFAGIGGEDKADVSPEVREGIVGPGMAFKAALGDQAEIVATFICGDNYCANNLDAVAARMVETVKSFGA
DGLIAGPAFNAGRYGTACGAVCAAVNKQLGLPVVSGMYRESPGVDLYRKEVTIVETADSARGMGKAVPAMAAVVLKLLRG
EEIADPAAEGVFPKGIRKNMFYDEPGAERAVRMLIKKVGGEEFKTEYAMPIFDRVEPRPAIADMSRATIAVVTSGGIVPE
GNPDHIAASSAQNFGAYSIEGVTDLEKGRYLTAHGGYDQTYANQDPDRVLPIDVLRDLEKEGRIGKLYNVFYTTVGNGTS
VANSRKFGTEIGSQLKAAHVDGVILTST*GTCTRCGATLAKAIEEAADVPVVHMCTIVPISLSIGANRIVPTVSIPHPLG
NPELSAAEEKHLRRELVLKALQALSTGVDGQTVF
>Mature_433_residues
AYKLVHYINQFFAGIGGEDKADVSPEVREGIVGPGMAFKAALGDQAEIVATFICGDNYCANNLDAVAARMVETVKSFGAD
GLIAGPAFNAGRYGTACGAVCAAVNKQLGLPVVSGMYRESPGVDLYRKEVTIVETADSARGMGKAVPAMAAVVLKLLRGE
EIADPAAEGVFPKGIRKNMFYDEPGAERAVRMLIKKVGGEEFKTEYAMPIFDRVEPRPAIADMSRATIAVVTSGGIVPEG
NPDHIAASSAQNFGAYSIEGVTDLEKGRYLTAHGGYDQTYANQDPDRVLPIDVLRDLEKEGRIGKLYNVFYTTVGNGTSV
ANSRKFGTEIGSQLKAAHVDGVILTST*GTCTRCGATLAKAIEEAADVPVVHMCTIVPISLSIGANRIVPTVSIPHPLGN
PELSAAEEKHLRRELVLKALQALSTGVDGQTVF

Specific function: In the first step of glycine reductase, the substrate is bound to component PB via a Schiff base intermediate. Then the PB- activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated seleno

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the grdB/grdF/grdH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010186
- InterPro:   IPR022787
- InterPro:   IPR010187 [H]

Pfam domain/function: PF07355 GRDB [H]

EC number: =1.21.4.2 [H]

Molecular weight: Translated: 45765; Mature: 45634

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYKLVHYINQFFAGIGGEDKADVSPEVREGIVGPGMAFKAALGDQAEIVATFICGDNYC
CHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHCCCCCEEEEEEEECCCCC
ANNLDAVAARMVETVKSFGADGLIAGPAFNAGRYGTACGAVCAAVNKQLGLPVVSGMYRE
CCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
SPGVDLYRKEVTIVETADSARGMGKAVPAMAAVVLKLLRGEEIADPAAEGVFPKGIRKNM
CCCCCEEECEEEEEECCHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHCC
FYDEPGAERAVRMLIKKVGGEEFKTEYAMPIFDRVEPRPAIADMSRATIAVVTSGGIVPE
CCCCCCHHHHHHHHHHHHCCHHHHHHCCCCHHHCCCCCCCHHHCCCCEEEEEECCCCCCC
GNPDHIAASSAQNFGAYSIEGVTDLEKGRYLTAHGGYDQTYANQDPDRVLPIDVLRDLEK
CCCCCEECCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCEECHHHHHHHHH
EGRIGKLYNVFYTTVGNGTSVANSRKFGTEIGSQLKAAHVDGVILTSTGTCTRCGATLAK
CCCHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHH
AIEEAADVPVVHMCTIVPISLSIGANRIVPTVSIPHPLGNPELSAAEEKHLRRELVLKAL
HHHHHHCCCEEEEHEEEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
QALSTGVDGQTVF
HHHHCCCCCCCCC
>Mature Secondary Structure 
AYKLVHYINQFFAGIGGEDKADVSPEVREGIVGPGMAFKAALGDQAEIVATFICGDNYC
HHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCHHHHHHCCCCCEEEEEEEECCCCC
ANNLDAVAARMVETVKSFGADGLIAGPAFNAGRYGTACGAVCAAVNKQLGLPVVSGMYRE
CCCHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHC
SPGVDLYRKEVTIVETADSARGMGKAVPAMAAVVLKLLRGEEIADPAAEGVFPKGIRKNM
CCCCCEEECEEEEEECCHHHCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCHHHHCC
FYDEPGAERAVRMLIKKVGGEEFKTEYAMPIFDRVEPRPAIADMSRATIAVVTSGGIVPE
CCCCCCHHHHHHHHHHHHCCHHHHHHCCCCHHHCCCCCCCHHHCCCCEEEEEECCCCCCC
GNPDHIAASSAQNFGAYSIEGVTDLEKGRYLTAHGGYDQTYANQDPDRVLPIDVLRDLEK
CCCCCEECCCCCCCCCEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCEECHHHHHHHHH
EGRIGKLYNVFYTTVGNGTSVANSRKFGTEIGSQLKAAHVDGVILTSTGTCTRCGATLAK
CCCHHHEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHH
AIEEAADVPVVHMCTIVPISLSIGANRIVPTVSIPHPLGNPELSAAEEKHLRRELVLKAL
HHHHHHCCCEEEEHEEEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHH
QALSTGVDGQTVF
HHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA