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The map label for this gene is speB1 [H]

Identifier: 220903360

GI number: 220903360

Start: 96075

End: 96959

Strand: Direct

Name: speB1 [H]

Synonym: Ddes_0074

Alternate gene names: 220903360

Gene position: 96075-96959 (Clockwise)

Preceding gene: 220903359

Following gene: 220903361

Centisome position: 3.34

GC content: 62.6

Gene sequence:

>885_bases
ATGCAGCATTTTCTGGCATCAGAATACAGCCCTGTTTTGCCTGAACAGGCGGGTTTTCATATCATCCCCGTTCCGCTTGA
GCAGAGCGTTTCTTACGGCGCGGGTACGGCTGGCGGCCCTGCGGCTCTGCTCGAGGCCTCGCAGCAGCTTGAAGCCTGGG
AATGCGGACATGCCCCGGGCGAGACAGGTTTTTATACCGCGCCGCCTGTGGACTGCGGCGGCCCTGTTGAAAAGGTGCTC
GACCGCATCGAGGCTGCCACGGCCCGCGCCATTTCGTGTGCGGCCCTGCCCGTGCTGCTCGGCGGCGAGCATACCGTTAC
CCTTGGCGCACTGCGCGCCCTGGCAAAAGAAGCGCAACGCAGTCGCGAGCCTTTCGGCATCGTGCAGTTCGACGCCCATG
CCGACCTGCGGTCTTCGTATGAAGGAAGCCCCTATTCCCACGCCTGTGTGATGCACCGTGCCGTGGCCGATCTTGGCCTG
CCGCTGGTGCAGTTTGCCGTGCGCGACTTTTGCCGCGAAGAGGCCGAGGTGCGCAAGGCGCATAATGTTACGCATTATGA
TGCCTATTTCATGGCGCGTGTGGGCCTGCCCGAGCAGCCCCTGCCCGAGGATTTTCCCCGGCGTATCTATATCACCTTTG
ATGTGGACGCGTTTGACGCATCACTCATGCCTGCCACAGGCACACCTTCGCCCGGCGGCATAAGCTGGCGCGAGGCCCAC
TTCATTCTTGAGCGCTGCGTGGCCGGGCGCAGGGTAATCGGGCTTGATGTGGTGGAGCTGGCGCCCATACAGGGGCTGCA
CCATTGCAACTTTACGGCGGCCAAACTGACGCATCTGCTTATGGGGCTGGCCCATGCGGCCAATACCGGCCCGGATGGGG
CATGA

Upstream 100 bases:

>100_bases
TACCTTCCTTTCTTTTGCTGACAGCCTCCTCCAAAATAGAACGGCCTGCCTCCCCAAGCGGGCCGTTTTATTTTCACACA
GCGCAGACATGAGGACAGTC

Downstream 100 bases:

>100_bases
TCAGAAGCGCTGTGGCAGCCGCCCGCCCGCAGGCGGCCCCAACGGCTAACTGTAAGAGTGTTTCAGGCGGTCATTGCCCT
AAATGCAGTAATGGCGCTAC

Product: agmatinase

Products: NA

Alternate protein names: Agmatine ureohydrolase 1; AUH 1 [H]

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MQHFLASEYSPVLPEQAGFHIIPVPLEQSVSYGAGTAGGPAALLEASQQLEAWECGHAPGETGFYTAPPVDCGGPVEKVL
DRIEAATARAISCAALPVLLGGEHTVTLGALRALAKEAQRSREPFGIVQFDAHADLRSSYEGSPYSHACVMHRAVADLGL
PLVQFAVRDFCREEAEVRKAHNVTHYDAYFMARVGLPEQPLPEDFPRRIYITFDVDAFDASLMPATGTPSPGGISWREAH
FILERCVAGRRVIGLDVVELAPIQGLHHCNFTAAKLTHLLMGLAHAANTGPDGA

Sequences:

>Translated_294_residues
MQHFLASEYSPVLPEQAGFHIIPVPLEQSVSYGAGTAGGPAALLEASQQLEAWECGHAPGETGFYTAPPVDCGGPVEKVL
DRIEAATARAISCAALPVLLGGEHTVTLGALRALAKEAQRSREPFGIVQFDAHADLRSSYEGSPYSHACVMHRAVADLGL
PLVQFAVRDFCREEAEVRKAHNVTHYDAYFMARVGLPEQPLPEDFPRRIYITFDVDAFDASLMPATGTPSPGGISWREAH
FILERCVAGRRVIGLDVVELAPIQGLHHCNFTAAKLTHLLMGLAHAANTGPDGA
>Mature_294_residues
MQHFLASEYSPVLPEQAGFHIIPVPLEQSVSYGAGTAGGPAALLEASQQLEAWECGHAPGETGFYTAPPVDCGGPVEKVL
DRIEAATARAISCAALPVLLGGEHTVTLGALRALAKEAQRSREPFGIVQFDAHADLRSSYEGSPYSHACVMHRAVADLGL
PLVQFAVRDFCREEAEVRKAHNVTHYDAYFMARVGLPEQPLPEDFPRRIYITFDVDAFDASLMPATGTPSPGGISWREAH
FILERCVAGRRVIGLDVVELAPIQGLHHCNFTAAKLTHLLMGLAHAANTGPDGA

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=264, Percent_Identity=28.7878787878788, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI10947139, Length=310, Percent_Identity=25.1612903225806, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI4502215, Length=267, Percent_Identity=27.7153558052434, Blast_Score=72, Evalue=6e-13,
Organism=Escherichia coli, GI1789306, Length=259, Percent_Identity=29.7297297297297, Blast_Score=86, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6325146, Length=219, Percent_Identity=25.1141552511416, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24638886, Length=189, Percent_Identity=29.6296296296296, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005925
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 31540; Mature: 31540

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHFLASEYSPVLPEQAGFHIIPVPLEQSVSYGAGTAGGPAALLEASQQLEAWECGHAPG
CCCCCCCCCCCCCCCCCCCEEEECCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
ETGFYTAPPVDCGGPVEKVLDRIEAATARAISCAALPVLLGGEHTVTLGALRALAKEAQR
CCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHH
SREPFGIVQFDAHADLRSSYEGSPYSHACVMHRAVADLGLPLVQFAVRDFCREEAEVRKA
CCCCCEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
HNVTHYDAYFMARVGLPEQPLPEDFPRRIYITFDVDAFDASLMPATGTPSPGGISWREAH
HCCCHHHHHHHEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHH
FILERCVAGRRVIGLDVVELAPIQGLHHCNFTAAKLTHLLMGLAHAANTGPDGA
HHHHHHHCCCEEECCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQHFLASEYSPVLPEQAGFHIIPVPLEQSVSYGAGTAGGPAALLEASQQLEAWECGHAPG
CCCCCCCCCCCCCCCCCCCEEEECCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCC
ETGFYTAPPVDCGGPVEKVLDRIEAATARAISCAALPVLLGGEHTVTLGALRALAKEAQR
CCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHH
SREPFGIVQFDAHADLRSSYEGSPYSHACVMHRAVADLGLPLVQFAVRDFCREEAEVRKA
CCCCCEEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
HNVTHYDAYFMARVGLPEQPLPEDFPRRIYITFDVDAFDASLMPATGTPSPGGISWREAH
HCCCHHHHHHHEECCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHH
FILERCVAGRRVIGLDVVELAPIQGLHHCNFTAAKLTHLLMGLAHAANTGPDGA
HHHHHHHCCCEEECCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]