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The map label for this gene is dcd

Identifier: 218884447

GI number: 218884447

Start: 1069737

End: 1070282

Strand: Reverse

Name: dcd

Synonym: DKAM_1136

Alternate gene names: 218884447

Gene position: 1070282-1069737 (Counterclockwise)

Preceding gene: 218884448

Following gene: 218884446

Centisome position: 78.4

GC content: 47.99

Gene sequence:

>546_bases
ATGATTCTAAGCGACTGGGATATCCGGGTTTACATCGAGAAGAAGCTCCTGATTATAGACCCGTTATTCGATGATACAGT
GAGGGAGAATGGAGTGGACTTAAGGTTCGGGGACGAATTCTGTAGGTTCAAGAGGGAGAACAGTGTAGTTGATACCTCGA
GGGACGGGGTTGACAATGTGTTAGAGTGCTATAGGGTTAGAGGCGATGGGTTCGTGATAAACCCGTTGGAGCATGTTTTA
ACCACGACCCTTGAGTATGTTGAGTTCCCCCATGACCTAGTGGGCTTGGTGAATCTTAGAAGTACTTTTGCCCGCTTCGG
CTTATACATTCCGCCGACAGTGATAGATGCCGGGTTCAAGGGGAATATAACCATTGAACTCGTAGGTAGCACGGTACCGG
TTAAGGTTTATCCGGGTCAGAGATTCCTCCACTTAATACTGGCGAGGACCAGTAGCCCTGTGTACAAGCCTTACACGGGT
AAGTATCAGGGACAGCGAGGTGTAACACCGCCCAAGCTCGATAACAGCTCCTCTAAAAATTTTTAA

Upstream 100 bases:

>100_bases
GGAAGGCTATAGATACATTCAAGGAGTTAGAGGAGGCGTCCAGGGCGATCCATGAAATATTCCATGAATCACCTCAGCCA
CTTAGAAGGAGGGAGTAAGA

Downstream 100 bases:

>100_bases
ATACCAGCTAGTTTCTAATTCATGGTTTTAAACACTGTTTCAACTATCTAAGACTTGATGGTGGAGTGGGTCGGCTTGGT
TAATGATCCACTGGCTGTAG

Product: deoxycytidine triphosphate deaminase

Products: NA

Alternate protein names: dCTP deaminase

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MILSDWDIRVYIEKKLLIIDPLFDDTVRENGVDLRFGDEFCRFKRENSVVDTSRDGVDNVLECYRVRGDGFVINPLEHVL
TTTLEYVEFPHDLVGLVNLRSTFARFGLYIPPTVIDAGFKGNITIELVGSTVPVKVYPGQRFLHLILARTSSPVYKPYTG
KYQGQRGVTPPKLDNSSSKNF

Sequences:

>Translated_181_residues
MILSDWDIRVYIEKKLLIIDPLFDDTVRENGVDLRFGDEFCRFKRENSVVDTSRDGVDNVLECYRVRGDGFVINPLEHVL
TTTLEYVEFPHDLVGLVNLRSTFARFGLYIPPTVIDAGFKGNITIELVGSTVPVKVYPGQRFLHLILARTSSPVYKPYTG
KYQGQRGVTPPKLDNSSSKNF
>Mature_181_residues
MILSDWDIRVYIEKKLLIIDPLFDDTVRENGVDLRFGDEFCRFKRENSVVDTSRDGVDNVLECYRVRGDGFVINPLEHVL
TTTLEYVEFPHDLVGLVNLRSTFARFGLYIPPTVIDAGFKGNITIELVGSTVPVKVYPGQRFLHLILARTSSPVYKPYTG
KYQGQRGVTPPKLDNSSSKNF

Specific function: De novo synthesis of thymidylate. [C]

COG id: COG0717

COG function: function code F; Deoxycytidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dCTP deaminase family

Homologues:

Organism=Escherichia coli, GI1788379, Length=193, Percent_Identity=33.160621761658, Blast_Score=80, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCD_DESK1 (B8D5T1)

Other databases:

- EMBL:   CP001140
- RefSeq:   YP_002428829.1
- GeneID:   7171228
- GenomeReviews:   CP001140_GR
- KEGG:   dka:DKAM_1136
- HOGENOM:   HBG553199
- OMA:   FSGHVTL
- ProtClustDB:   PRK00416
- HAMAP:   MF_00146
- InterPro:   IPR011962
- InterPro:   IPR008180
- TIGRFAMs:   TIGR02274

Pfam domain/function: PF00692 dUTPase

EC number: =3.5.4.13

Molecular weight: Translated: 20561; Mature: 20561

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILSDWDIRVYIEKKLLIIDPLFDDTVRENGVDLRFGDEFCRFKRENSVVDTSRDGVDNV
CCCCCCEEEEEEEEEEEEEECCCCHHHHHCCCEEEECHHHHHHHCCCCCCCCCCCCHHHH
LECYRVRGDGFVINPLEHVLTTTLEYVEFPHDLVGLVNLRSTFARFGLYIPPTVIDAGFK
HHHHEECCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCC
GNITIELVGSTVPVKVYPGQRFLHLILARTSSPVYKPYTGKYQGQRGVTPPKLDNSSSKN
CCEEEEEECCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
F
C
>Mature Secondary Structure
MILSDWDIRVYIEKKLLIIDPLFDDTVRENGVDLRFGDEFCRFKRENSVVDTSRDGVDNV
CCCCCCEEEEEEEEEEEEEECCCCHHHHHCCCEEEECHHHHHHHCCCCCCCCCCCCHHHH
LECYRVRGDGFVINPLEHVLTTTLEYVEFPHDLVGLVNLRSTFARFGLYIPPTVIDAGFK
HHHHEECCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCC
GNITIELVGSTVPVKVYPGQRFLHLILARTSSPVYKPYTGKYQGQRGVTPPKLDNSSSKN
CCEEEEEECCEEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
F
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA