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The map label for this gene is yfnH [H]

Identifier: 218884448

GI number: 218884448

Start: 1070285

End: 1071136

Strand: Reverse

Name: yfnH [H]

Synonym: DKAM_1137

Alternate gene names: 218884448

Gene position: 1071136-1070285 (Counterclockwise)

Preceding gene: 218884450

Following gene: 218884447

Centisome position: 78.46

GC content: 46.13

Gene sequence:

>852_bases
TTGATTAAACAGGGGTTTATTAGGTTTTCCACGAGCCAGAGGGTGTTCGCTATCTTGAGGGAGTTCTGTACTGTGTTAAT
TATTTTTATATTACGTCTTGGATGGATACTAATGTGGTGTATTAGAATGCTCGCCGTGATCCTGGCTGGAGGATATGGTA
AAAGGCTTAGACCATACACGGATGACGTTCCTAAGCCAATGATCCCGGTTGGGGATAAACCTATCCTGGAATGGCAGATC
GAGTGGTTGAAAAAGTATGGGTTTAGGGAGATAGTTCTCCTAGTTGGCTATAGGAAGGAGAAGATAATAGAATATATTGG
TAGTGGGAGCAGGCTTGGCGTGAGGGTTACATACGTAGTTGAGGATGAACCCTTGGGGACCGGGGGAGCCATTAAGAACG
CTGAGCATGTCTTATCCAGGAACGGCACGTTCCTAGTTATCAACGGAGATATAATTACCAATCTCAACCCGCTAAAGCTA
GTCGAGAAACTCGAGGGTTCAAGGTATCTTGGTGTAATAGCATCGATACCTCTGCCAAGCCCATATGGTGTCCTCGAAAT
AGAGGATGAAGACAGGGTTAAGGGATTTGTTGAGAAGCCCCAGTTAAGTGACTACTGGATCAATGCCGGAGTATACGCTT
TAAACCCTGAGGCTTTAAGATACTTCCCAGAGAAAGGGGACTTGGAGAAAACAGCGTTCCCTGCCATGGCCCGGGATGGA
GTGCTAGGTACGGTGAGATATACTGGTGTATTCTGGAAGGCTATAGATACATTCAAGGAGTTAGAGGAGGCGTCCAGGGC
GATCCATGAAATATTCCATGAATCACCTCAGCCACTTAGAAGGAGGGAGTAA

Upstream 100 bases:

>100_bases
AGGATGAGTCATGGTATGCCGCCGCGGGGACTTGAACCCCGGACATCCCGGTCTTCAGCCGGGCGCTCTCCCAGCTGAGC
TACGGCGGCACCATTATTAA

Downstream 100 bases:

>100_bases
GAATGATTCTAAGCGACTGGGATATCCGGGTTTACATCGAGAAGAAGCTCCTGATTATAGACCCGTTATTCGATGATACA
GTGAGGGAGAATGGAGTGGA

Product: Putative sugar-phosphate nucleotidyl transferase

Products: NA

Alternate protein names: CDP-glucose pyrophosphorylase [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MIKQGFIRFSTSQRVFAILREFCTVLIIFILRLGWILMWCIRMLAVILAGGYGKRLRPYTDDVPKPMIPVGDKPILEWQI
EWLKKYGFREIVLLVGYRKEKIIEYIGSGSRLGVRVTYVVEDEPLGTGGAIKNAEHVLSRNGTFLVINGDIITNLNPLKL
VEKLEGSRYLGVIASIPLPSPYGVLEIEDEDRVKGFVEKPQLSDYWINAGVYALNPEALRYFPEKGDLEKTAFPAMARDG
VLGTVRYTGVFWKAIDTFKELEEASRAIHEIFHESPQPLRRRE

Sequences:

>Translated_283_residues
MIKQGFIRFSTSQRVFAILREFCTVLIIFILRLGWILMWCIRMLAVILAGGYGKRLRPYTDDVPKPMIPVGDKPILEWQI
EWLKKYGFREIVLLVGYRKEKIIEYIGSGSRLGVRVTYVVEDEPLGTGGAIKNAEHVLSRNGTFLVINGDIITNLNPLKL
VEKLEGSRYLGVIASIPLPSPYGVLEIEDEDRVKGFVEKPQLSDYWINAGVYALNPEALRYFPEKGDLEKTAFPAMARDG
VLGTVRYTGVFWKAIDTFKELEEASRAIHEIFHESPQPLRRRE
>Mature_283_residues
MIKQGFIRFSTSQRVFAILREFCTVLIIFILRLGWILMWCIRMLAVILAGGYGKRLRPYTDDVPKPMIPVGDKPILEWQI
EWLKKYGFREIVLLVGYRKEKIIEYIGSGSRLGVRVTYVVEDEPLGTGGAIKNAEHVLSRNGTFLVINGDIITNLNPLKL
VEKLEGSRYLGVIASIPLPSPYGVLEIEDEDRVKGFVEKPQLSDYWINAGVYALNPEALRYFPEKGDLEKTAFPAMARDG
VLGTVRYTGVFWKAIDTFKELEEASRAIHEIFHESPQPLRRRE

Specific function: Catalyzes the transfer of a CMP moiety from CTP to glucose 1-phosphate [H]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucose-1-phosphate cytidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=226, Percent_Identity=37.6106194690265, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI11761619, Length=226, Percent_Identity=37.6106194690265, Blast_Score=129, Evalue=3e-30,
Organism=Homo sapiens, GI31881779, Length=258, Percent_Identity=29.0697674418605, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI45447090, Length=258, Percent_Identity=29.0697674418605, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1790224, Length=242, Percent_Identity=28.099173553719, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788351, Length=239, Percent_Identity=26.3598326359833, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI133931050, Length=225, Percent_Identity=36.8888888888889, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17509979, Length=240, Percent_Identity=29.5833333333333, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509981, Length=228, Percent_Identity=28.5087719298246, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6320148, Length=227, Percent_Identity=38.3259911894273, Blast_Score=127, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320417, Length=126, Percent_Identity=26.984126984127, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355443, Length=223, Percent_Identity=36.7713004484305, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24644084, Length=223, Percent_Identity=36.7713004484305, Blast_Score=126, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013446
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.33 [H]

Molecular weight: Translated: 32291; Mature: 32291

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKQGFIRFSTSQRVFAILREFCTVLIIFILRLGWILMWCIRMLAVILAGGYGKRLRPYT
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DDVPKPMIPVGDKPILEWQIEWLKKYGFREIVLLVGYRKEKIIEYIGSGSRLGVRVTYVV
CCCCCCCCCCCCCCHHHHHHHHHHHCCHHEEEHHHCCCHHHHHHHHCCCCEEEEEEEEEE
EDEPLGTGGAIKNAEHVLSRNGTFLVINGDIITNLNPLKLVEKLEGSRYLGVIASIPLPS
ECCCCCCCCCCCHHHHHHHCCCEEEEECCCEECCCCHHHHHHHHCCCEEEEEEEECCCCC
PYGVLEIEDEDRVKGFVEKPQLSDYWINAGVYALNPEALRYFPEKGDLEKTAFPAMARDG
CCCEEEECCCHHHHHHHCCCCCCCEEECCCEEEECHHHHHCCCCCCCCCHHHCCHHHCCC
VLGTVRYTGVFWKAIDTFKELEEASRAIHEIFHESPQPLRRRE
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIKQGFIRFSTSQRVFAILREFCTVLIIFILRLGWILMWCIRMLAVILAGGYGKRLRPYT
CCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DDVPKPMIPVGDKPILEWQIEWLKKYGFREIVLLVGYRKEKIIEYIGSGSRLGVRVTYVV
CCCCCCCCCCCCCCHHHHHHHHHHHCCHHEEEHHHCCCHHHHHHHHCCCCEEEEEEEEEE
EDEPLGTGGAIKNAEHVLSRNGTFLVINGDIITNLNPLKLVEKLEGSRYLGVIASIPLPS
ECCCCCCCCCCCHHHHHHHCCCEEEEECCCEECCCCHHHHHHHHCCCEEEEEEEECCCCC
PYGVLEIEDEDRVKGFVEKPQLSDYWINAGVYALNPEALRYFPEKGDLEKTAFPAMARDG
CCCEEEECCCHHHHHHHCCCCCCCEEECCCEEEECHHHHHCCCCCCCCCHHHCCHHHCCC
VLGTVRYTGVFWKAIDTFKELEEASRAIHEIFHESPQPLRRRE
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]