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The map label for this gene is ychE [H]

Identifier: 218533126

GI number: 218533126

Start: 5623612

End: 5624253

Strand: Reverse

Name: ychE [H]

Synonym: Mchl_5252

Alternate gene names: 218533126

Gene position: 5624253-5623612 (Counterclockwise)

Preceding gene: 218533129

Following gene: 218533124

Centisome position: 97.34

GC content: 65.89

Gene sequence:

>642_bases
ATGTCTGTCGATCTGTCCTTCGTCACGAAGGTCTTCGCCGCTTTGTTCGCCATCATGAACCCGATCGCGAATGTGCCGGT
GTTCCTCTCCCTGACCGATGGCGCGTCCGACGCCGTGCGGCGGCACGTTGCGGTCAAGGCCGCTGTCGGGACCACGATCG
GCTGCCTCGTCTCGATTGTGGCCGGGCAGGCCGTCCTGGATGCCTTCGGACTCAGCGTCGACGACTTCCGTCTGGCGGGC
GGGCTCATCGTCCTAACGATCGCGCTCTCGATGCTTCAGGGCTCGTCGAGCCAGACGCATGGCCGCAGTCCCAAGGAGAA
GGAAGACCAGATCGATGCGGACAGCGTCGCCATCTACCCGCTGACCATCCCCCTGCTCGTCGGGCCGGGGACGATCGCGA
CGCTCACCGTGTTCGGCCAAACCGCCAAGGCGCAGGCCAAATGGCCGGAACTCGTGCTCGGTGTCGGCGCCTTTCTCACG
CTTCTGACGGTCGCGCTGCTCTCGGCCCCCTGGCTCGGCCACCATCTGTCCGCGACGGCCACCGCGATCACGCGCCGCCT
GATGGGCATGATCCTGGCCGCGGTTGCGATGGAGATGATCGTGACGAGCCTGCGCAACCTGTTCCCCGGCCTCAGCCATT
GA

Upstream 100 bases:

>100_bases
GTGGGGCGCCGGCGTGACCGCCCTTCGCTGCCTGCGTACCCAGCGCCGGGCCGAAGCCGAAGCTATGCTATGGGTCCGAG
GCTCGAAACCGGGATTCGCG

Downstream 100 bases:

>100_bases
GCCGCAGAGAGCGCTCCAGACGGCGGCGCTTCTCGACGCCGCGTTACAGCCAGCCCTTCGCCTTGAAATAGAGCAGCGGC
ACGATCGCCGAGATCGCGAT

Product: multiple antibiotic resistance (MarC)-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 212

Protein sequence:

>213_residues
MSVDLSFVTKVFAALFAIMNPIANVPVFLSLTDGASDAVRRHVAVKAAVGTTIGCLVSIVAGQAVLDAFGLSVDDFRLAG
GLIVLTIALSMLQGSSSQTHGRSPKEKEDQIDADSVAIYPLTIPLLVGPGTIATLTVFGQTAKAQAKWPELVLGVGAFLT
LLTVALLSAPWLGHHLSATATAITRRLMGMILAAVAMEMIVTSLRNLFPGLSH

Sequences:

>Translated_213_residues
MSVDLSFVTKVFAALFAIMNPIANVPVFLSLTDGASDAVRRHVAVKAAVGTTIGCLVSIVAGQAVLDAFGLSVDDFRLAG
GLIVLTIALSMLQGSSSQTHGRSPKEKEDQIDADSVAIYPLTIPLLVGPGTIATLTVFGQTAKAQAKWPELVLGVGAFLT
LLTVALLSAPWLGHHLSATATAITRRLMGMILAAVAMEMIVTSLRNLFPGLSH
>Mature_212_residues
SVDLSFVTKVFAALFAIMNPIANVPVFLSLTDGASDAVRRHVAVKAAVGTTIGCLVSIVAGQAVLDAFGLSVDDFRLAGG
LIVLTIALSMLQGSSSQTHGRSPKEKEDQIDADSVAIYPLTIPLLVGPGTIATLTVFGQTAKAQAKWPELVLGVGAFLTL
LTVALLSAPWLGHHLSATATAITRRLMGMILAAVAMEMIVTSLRNLFPGLSH

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787494, Length=208, Percent_Identity=33.1730769230769, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1787809, Length=194, Percent_Identity=28.8659793814433, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789842, Length=201, Percent_Identity=28.3582089552239, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 22175; Mature: 22044

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVDLSFVTKVFAALFAIMNPIANVPVFLSLTDGASDAVRRHVAVKAAVGTTIGCLVSIV
CCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQAVLDAFGLSVDDFRLAGGLIVLTIALSMLQGSSSQTHGRSPKEKEDQIDADSVAIYP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCEEEEE
LTIPLLVGPGTIATLTVFGQTAKAQAKWPELVLGVGAFLTLLTVALLSAPWLGHHLSATA
EEEEEEECCCHHEEEEECCCCHHCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TAITRRLMGMILAAVAMEMIVTSLRNLFPGLSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SVDLSFVTKVFAALFAIMNPIANVPVFLSLTDGASDAVRRHVAVKAAVGTTIGCLVSIV
CCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AGQAVLDAFGLSVDDFRLAGGLIVLTIALSMLQGSSSQTHGRSPKEKEDQIDADSVAIYP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHCCCCCCEEEEE
LTIPLLVGPGTIATLTVFGQTAKAQAKWPELVLGVGAFLTLLTVALLSAPWLGHHLSATA
EEEEEEECCCHHEEEEECCCCHHCHHCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
TAITRRLMGMILAAVAMEMIVTSLRNLFPGLSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2015910; 9097039; 9278503 [H]