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The map label for this gene is groES [H]

Identifier: 218533124

GI number: 218533124

Start: 5622059

End: 5622349

Strand: Reverse

Name: groES [H]

Synonym: Mchl_5250

Alternate gene names: 218533124

Gene position: 5622349-5622059 (Counterclockwise)

Preceding gene: 218533126

Following gene: 218533123

Centisome position: 97.31

GC content: 63.92

Gene sequence:

>291_bases
ATGAAGTTCCGTCCGCTGCACGACCGCGTCGTCGTCCGTCGCATCGAGAGCGAAGAGAAGACGAAAGGCGGCATCATCAT
CCCGGATACCGCCAAGGAGAAGCCGCAAGAGGGCGAGATCGTCGCCGTCGGCCCCGGCGCTCGCGACGAGCAGGGCCGCG
TCAACGCCCTCGACGTGAAGGTCGGTGACCGCGTGCTGTTCGGCAAGTGGTCCGGCACCGAGGTCAAGATCGACGGCCAG
GATCTCCTCATCATGAAGGAATCCGACATCATGGGCGTCGTCGCCCTCTAA

Upstream 100 bases:

>100_bases
TCGTTAGCACTCACTTGCTTGGAGTGCTAACAATCAGGTGGAGCGCGGTCGTCCCGGCCGCATGAAGACCAACCGCCATT
CCGAAGCAAGAGGGCAGCTC

Downstream 100 bases:

>100_bases
GGCGCGCAACCCCTCCACCGCCCTTCGAGGCCGCCAGGGCTTTTGCCCTCGGCCGGCTTCAGGGCCCCTTCCATCATTCG
AGGTAAACTCACATGGCAGC

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 96; Mature: 96

Protein sequence:

>96_residues
MKFRPLHDRVVVRRIESEEKTKGGIIIPDTAKEKPQEGEIVAVGPGARDEQGRVNALDVKVGDRVLFGKWSGTEVKIDGQ
DLLIMKESDIMGVVAL

Sequences:

>Translated_96_residues
MKFRPLHDRVVVRRIESEEKTKGGIIIPDTAKEKPQEGEIVAVGPGARDEQGRVNALDVKVGDRVLFGKWSGTEVKIDGQ
DLLIMKESDIMGVVAL
>Mature_96_residues
MKFRPLHDRVVVRRIESEEKTKGGIIIPDTAKEKPQEGEIVAVGPGARDEQGRVNALDVKVGDRVLFGKWSGTEVKIDGQ
DLLIMKESDIMGVVAL

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=91, Percent_Identity=41.7582417582418, Blast_Score=71, Evalue=2e-13,
Organism=Homo sapiens, GI169210012, Length=91, Percent_Identity=38.4615384615385, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=50.5263157894737, Blast_Score=90, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17555568, Length=91, Percent_Identity=46.1538461538462, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6324594, Length=92, Percent_Identity=38.0434782608696, Blast_Score=71, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21356029, Length=93, Percent_Identity=43.010752688172, Blast_Score=75, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21358317, Length=93, Percent_Identity=40.8602150537634, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10567; Mature: 10567

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRPLHDRVVVRRIESEEKTKGGIIIPDTAKEKPQEGEIVAVGPGARDEQGRVNALDVK
CCCCCCCHHHHEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEE
VGDRVLFGKWSGTEVKIDGQDLLIMKESDIMGVVAL
ECCEEEEECCCCCEEEECCCEEEEEECCCEEEEEEC
>Mature Secondary Structure
MKFRPLHDRVVVRRIESEEKTKGGIIIPDTAKEKPQEGEIVAVGPGARDEQGRVNALDVK
CCCCCCCHHHHEEECCCCCCCCCCEEECCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEE
VGDRVLFGKWSGTEVKIDGQDLLIMKESDIMGVVAL
ECCEEEEECCCCCEEEECCCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA