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The map label for this gene is murQ [H]

Identifier: 218532582

GI number: 218532582

Start: 4976835

End: 4977722

Strand: Reverse

Name: murQ [H]

Synonym: Mchl_4696

Alternate gene names: 218532582

Gene position: 4977722-4976835 (Counterclockwise)

Preceding gene: 218532585

Following gene: 218532581

Centisome position: 86.15

GC content: 74.66

Gene sequence:

>888_bases
ATGAGAACCGAGGACGCCAGCGCCCGCTACGTCGATCTCGACGCCTGGGGCGGGCTCGACATCCTCCAGGCGCTCTGGGA
GGGCCAGCTCGCGGCAGTGGCGGCGGTGGGGCCGGCCCTGCCGGCGATCGATGGGGCGGCGCGGGCCGCCGAGCCGGGCC
TGCGCGAGGGCGGACGGCTGGTCTATGTCGGCGCCGGCACCTCCGCGCGGATCGGCGTGCAGGACGGGGCGGAATTGCCG
CCGACCTTCGACTGGCCGGAGGCGCAGCTCGGTTTCGCCATCGCCGGCGGGGAGGGCGCCCTGTTGCGCGCGGTGGAGGA
TGCGGAGGATTCCGCCGCCGACGGCGCCGCCTGGATCGCAAGCGCCGAGATCGGCCCGCGCGACGTGGTGGTGGGGCTGG
CCGCCAGCGGCTCGACGCCGTTCACCGTCGAGGCGCTGAAGGCCGCCCGCAGCCGCGGCGCCGTCACCGTCGGCGTCAGC
AACAACCCCGACGCGCCGATCCTGCGCGAGGCCGCCCATGGCATCCTCGCCGCCACGGGGGCCGAGGTGCTGGCGGGCTC
CACCCGCATGAAGGCGGGCACGGCCCAGAAGGTGATCCTCAACCTGTTCTCGACCCTGGTGATGATCCGGCTCGGCCGGG
TCTATCGCGGGCGGATGGTGGCGATGCGCGCGACCAACCGGAAGCTGCGCGCCCGCGGCGTCGCCATGGTCTCCGAGCTC
GCCGGCTGCCCGGCAGACGTCGCCGCCGACGCCCTGACGCGAGCCGAGGGCGACATCAAGCGTGCGGTGCTGCTCGCAGG
GGGGATGAGCGCCATGCGGGCCGACGACCTGCTCCTGCGCCATGACGGCAACCTGCGCCGGGCGCTTCGTGAGGTGGGCC
GATCATGA

Upstream 100 bases:

>100_bases
CCGCATCGGCGATGACCTCTTTCGAACAGGCGAGGCGCGTGATGCAGTGCCGAAGACGGAATCAAGTAAACGCGATGCGG
ACGAGCAGGGCACACAAGGC

Downstream 100 bases:

>100_bases
GCGCAACGACCTTCATGGCGCGGGAGATCGCCGAGATCCCCGACGCCGCCTCTCTGCTGGTAGCCGGCGAAGCAGCCCGG
ATCGGCGCGACGCTGCGGGC

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MRTEDASARYVDLDAWGGLDILQALWEGQLAAVAAVGPALPAIDGAARAAEPGLREGGRLVYVGAGTSARIGVQDGAELP
PTFDWPEAQLGFAIAGGEGALLRAVEDAEDSAADGAAWIASAEIGPRDVVVGLAASGSTPFTVEALKAARSRGAVTVGVS
NNPDAPILREAAHGILAATGAEVLAGSTRMKAGTAQKVILNLFSTLVMIRLGRVYRGRMVAMRATNRKLRARGVAMVSEL
AGCPADVAADALTRAEGDIKRAVLLAGGMSAMRADDLLLRHDGNLRRALREVGRS

Sequences:

>Translated_295_residues
MRTEDASARYVDLDAWGGLDILQALWEGQLAAVAAVGPALPAIDGAARAAEPGLREGGRLVYVGAGTSARIGVQDGAELP
PTFDWPEAQLGFAIAGGEGALLRAVEDAEDSAADGAAWIASAEIGPRDVVVGLAASGSTPFTVEALKAARSRGAVTVGVS
NNPDAPILREAAHGILAATGAEVLAGSTRMKAGTAQKVILNLFSTLVMIRLGRVYRGRMVAMRATNRKLRARGVAMVSEL
AGCPADVAADALTRAEGDIKRAVLLAGGMSAMRADDLLLRHDGNLRRALREVGRS
>Mature_295_residues
MRTEDASARYVDLDAWGGLDILQALWEGQLAAVAAVGPALPAIDGAARAAEPGLREGGRLVYVGAGTSARIGVQDGAELP
PTFDWPEAQLGFAIAGGEGALLRAVEDAEDSAADGAAWIASAEIGPRDVVVGLAASGSTPFTVEALKAARSRGAVTVGVS
NNPDAPILREAAHGILAATGAEVLAGSTRMKAGTAQKVILNLFSTLVMIRLGRVYRGRMVAMRATNRKLRARGVAMVSEL
AGCPADVAADALTRAEGDIKRAVLLAGGMSAMRADDLLLRHDGNLRRALREVGRS

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=290, Percent_Identity=39.3103448275862, Blast_Score=187, Evalue=6e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 30367; Mature: 30367

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTEDASARYVDLDAWGGLDILQALWEGQLAAVAAVGPALPAIDGAARAAEPGLREGGRL
CCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHCCCCCCCCCEE
VYVGAGTSARIGVQDGAELPPTFDWPEAQLGFAIAGGEGALLRAVEDAEDSAADGAAWIA
EEEECCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCEEEE
SAEIGPRDVVVGLAASGSTPFTVEALKAARSRGAVTVGVSNNPDAPILREAAHGILAATG
ECCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCC
AEVLAGSTRMKAGTAQKVILNLFSTLVMIRLGRVYRGRMVAMRATNRKLRARGVAMVSEL
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHH
AGCPADVAADALTRAEGDIKRAVLLAGGMSAMRADDLLLRHDGNLRRALREVGRS
CCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCEEEECCCHHHHHHHHHCCC
>Mature Secondary Structure
MRTEDASARYVDLDAWGGLDILQALWEGQLAAVAAVGPALPAIDGAARAAEPGLREGGRL
CCCCCCCCEEEEECCCCCHHHHHHHHCCCHHHHHHHCCCCCCCCCHHHHCCCCCCCCCEE
VYVGAGTSARIGVQDGAELPPTFDWPEAQLGFAIAGGEGALLRAVEDAEDSAADGAAWIA
EEEECCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCEEEE
SAEIGPRDVVVGLAASGSTPFTVEALKAARSRGAVTVGVSNNPDAPILREAAHGILAATG
ECCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHCC
AEVLAGSTRMKAGTAQKVILNLFSTLVMIRLGRVYRGRMVAMRATNRKLRARGVAMVSEL
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHH
AGCPADVAADALTRAEGDIKRAVLLAGGMSAMRADDLLLRHDGNLRRALREVGRS
CCCCHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHCEEEECCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA