Click here to switch to the map view.

The map label for this gene is alr [H]

Identifier: 218532193

GI number: 218532193

Start: 4546780

End: 4547808

Strand: Reverse

Name: alr [H]

Synonym: Mchl_4305

Alternate gene names: 218532193

Gene position: 4547808-4546780 (Counterclockwise)

Preceding gene: 218532194

Following gene: 218532192

Centisome position: 78.71

GC content: 72.01

Gene sequence:

>1029_bases
GTGGTGGCGAACTGGCGGGCGCTCGGCGCGTGCGCGCCGCAGGCCGAGTGCGGCGCCGTGGTGAAGGCGGACGCCTATGG
CTGCGGCCTCGCGGCGGTCGCCCCGGCCCTATGGCGGGCGGGCTGCCGGACATTCTTCGTGGCGCACCTCTCCGAGGGCA
TCGCCGCGCGGAAAATGCTGCCGGAGGCGGCGCTCTACGTGCTCAATGGTCTGCCGCCCGGCCACGCGGAGGCGTTTCGC
GCCCACCGCCTGCGCCCGGTCCTGGGGGACGCGCAAGAACTCGCCGAGTGGGCCGAGGCCATGCAGGGCGGGGGGCCGGC
CGCGCTCCACGTCGATACCGGCATGAACCGGCTCGGCCTCTCCGTCGCGGAGGCTCTGGCGCTGGCCGGCGATCCGGTGA
TCGCGCGCGCCGGCATCGACCTCGTGATGAGCCATCTCGTCAGCGCGGAATTGCCCGACGATCCGCTCAACGCGCGCCAA
GCCGCCGATTTCGCCCGTGTGCGGGCGGCCTTTCCGCAGATGCGCGCCTCGCTTGCCAATTCCTCGGGCACCTGCCTTGC
GAATGACGCCCGCCACGACCTGCTGCGGCCGGGCTATGCGCTCTTCGGCGGTAACCCGGATCCGGGCCAACCCAATCCGA
TGCGGCCGGTGGTGCGGCTGGAGGCGACGATCCTGCAGGTCCGTGACGTCGAGGCCGGCGCGACCTGCGGCTACAACGCC
CGCTGGCAGGCCCCGGCCCCGCGCCGGCTGGCCACGCTCTCGCTCGGCTACGCCGACGGCTATCCCCGCTCGGCCAGCAA
CAGCGGCCACGCGCTGGTCGGCGGCATGCCCTGCCCGATCGTCGGCCTGATCTCGATGGACCTCATCATCCTCGACGTCA
CCGACGCATCGCAGGCCCGGCGCGGAGGCACCGCCACGCTGATCGGCGACAGCCTCGACATCGACACGGTGGGGCAAGCC
GCCGGCACCATCGGCTACGAGATCCTGACGAGCCTGGGTTCCCGTTATGTTCGCAACTATGTAGAGTGA

Upstream 100 bases:

>100_bases
GTCTGTCATAGCGCCCGTAGAATCCTTCCCGGAAAACCCGACCACGGGCGATCCATTCCGCAGCGGCCACGGCGCCCGTC
TGACGGTCGATCTCTCGGCC

Downstream 100 bases:

>100_bases
CCGATCTTTCCCACCCATTCCCCTCATCCTGAGGCGGCGGCGCGAAGCGGCGCCCTCGAAGGAGGGCTCCAGGGATCGCG
TGGCCGGCTGGAGCCCTCCT

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MVANWRALGACAPQAECGAVVKADAYGCGLAAVAPALWRAGCRTFFVAHLSEGIAARKMLPEAALYVLNGLPPGHAEAFR
AHRLRPVLGDAQELAEWAEAMQGGGPAALHVDTGMNRLGLSVAEALALAGDPVIARAGIDLVMSHLVSAELPDDPLNARQ
AADFARVRAAFPQMRASLANSSGTCLANDARHDLLRPGYALFGGNPDPGQPNPMRPVVRLEATILQVRDVEAGATCGYNA
RWQAPAPRRLATLSLGYADGYPRSASNSGHALVGGMPCPIVGLISMDLIILDVTDASQARRGGTATLIGDSLDIDTVGQA
AGTIGYEILTSLGSRYVRNYVE

Sequences:

>Translated_342_residues
MVANWRALGACAPQAECGAVVKADAYGCGLAAVAPALWRAGCRTFFVAHLSEGIAARKMLPEAALYVLNGLPPGHAEAFR
AHRLRPVLGDAQELAEWAEAMQGGGPAALHVDTGMNRLGLSVAEALALAGDPVIARAGIDLVMSHLVSAELPDDPLNARQ
AADFARVRAAFPQMRASLANSSGTCLANDARHDLLRPGYALFGGNPDPGQPNPMRPVVRLEATILQVRDVEAGATCGYNA
RWQAPAPRRLATLSLGYADGYPRSASNSGHALVGGMPCPIVGLISMDLIILDVTDASQARRGGTATLIGDSLDIDTVGQA
AGTIGYEILTSLGSRYVRNYVE
>Mature_342_residues
MVANWRALGACAPQAECGAVVKADAYGCGLAAVAPALWRAGCRTFFVAHLSEGIAARKMLPEAALYVLNGLPPGHAEAFR
AHRLRPVLGDAQELAEWAEAMQGGGPAALHVDTGMNRLGLSVAEALALAGDPVIARAGIDLVMSHLVSAELPDDPLNARQ
AADFARVRAAFPQMRASLANSSGTCLANDARHDLLRPGYALFGGNPDPGQPNPMRPVVRLEATILQVRDVEAGATCGYNA
RWQAPAPRRLATLSLGYADGYPRSASNSGHALVGGMPCPIVGLISMDLIILDVTDASQARRGGTATLIGDSLDIDTVGQA
AGTIGYEILTSLGSRYVRNYVE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1787439, Length=338, Percent_Identity=33.4319526627219, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790487, Length=353, Percent_Identity=31.1614730878187, Blast_Score=133, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 35696; Mature: 35696

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVANWRALGACAPQAECGAVVKADAYGCGLAAVAPALWRAGCRTFFVAHLSEGIAARKML
CCCCCCHHCCCCCCHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PEAALYVLNGLPPGHAEAFRAHRLRPVLGDAQELAEWAEAMQGGGPAALHVDTGMNRLGL
HHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
SVAEALALAGDPVIARAGIDLVMSHLVSAELPDDPLNARQAADFARVRAAFPQMRASLAN
HHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
SSGTCLANDARHDLLRPGYALFGGNPDPGQPNPMRPVVRLEATILQVRDVEAGATCGYNA
CCCCEEECCHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCCC
RWQAPAPRRLATLSLGYADGYPRSASNSGHALVGGMPCPIVGLISMDLIILDVTDASQAR
EECCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCHHHHHHCEEEEEEECCHHHHH
RGGTATLIGDSLDIDTVGQAAGTIGYEILTSLGSRYVRNYVE
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVANWRALGACAPQAECGAVVKADAYGCGLAAVAPALWRAGCRTFFVAHLSEGIAARKML
CCCCCCHHCCCCCCHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PEAALYVLNGLPPGHAEAFRAHRLRPVLGDAQELAEWAEAMQGGGPAALHVDTGMNRLGL
HHHHHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
SVAEALALAGDPVIARAGIDLVMSHLVSAELPDDPLNARQAADFARVRAAFPQMRASLAN
HHHHHHHHCCCCEEEHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
SSGTCLANDARHDLLRPGYALFGGNPDPGQPNPMRPVVRLEATILQVRDVEAGATCGYNA
CCCCEEECCHHHHHHCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCCC
RWQAPAPRRLATLSLGYADGYPRSASNSGHALVGGMPCPIVGLISMDLIILDVTDASQAR
EECCCCCCCEEEEEECCCCCCCCCCCCCCCEEECCCCCCHHHHHHCEEEEEEECCHHHHH
RGGTATLIGDSLDIDTVGQAAGTIGYEILTSLGSRYVRNYVE
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA