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The map label for this gene is pabA [H]

Identifier: 218532163

GI number: 218532163

Start: 4512314

End: 4512943

Strand: Reverse

Name: pabA [H]

Synonym: Mchl_4275

Alternate gene names: 218532163

Gene position: 4512943-4512314 (Counterclockwise)

Preceding gene: 218532164

Following gene: 218532162

Centisome position: 78.11

GC content: 71.27

Gene sequence:

>630_bases
ATGATCCTCGTCGTCGACAACTACGATTCCTTCGTCTTCAACGTGGTGCGCTACTTCGAGGAGTTGGGCGAGACCGTCGA
GGTCGTGCGCAACGACGCGCTCGATGTGGCCGGCATCCGCGCGCGGAACCCGGAGGCGGTGGTGATCTCGCCCGGCCCCT
GCACCCCGGCGGAGGCCGGCGTGAGCCTGCCGGCCATCCGCGAATTGTCCGGCGAGGTGCCGATCCTCGGCGTCTGCCTC
GGGCATCAGGCGATCGGCGCGGCGTTCGGCGGCCGGGTCGAGCGGGCGGGCCGCCCGCTGCACGGCCACGCCACGCCGAT
CCGGCACGGGGGCGAGCGGCTGTTCGCAGGGCTGCCGCAGCCGATGCAGGTCGGGCGCTACCACTCGCTGATCGTGGCGC
CGACGCCGGAGATGGAGCGGCATCTCACGGTCGATGCCGCCTCCGGGGAGGGCGAGGTGATGGCGCTGTCGCACCGCAGC
CACCCGACCTGGGGCATCCAGTTCCACCCGGAATCGGTGCTGACCGAGAACGGCCACGCGCTGTTTTCCAACTTCCTGAA
GGAGGCCCGTGCGTGGCGGGCGGCGGGCGCGTCGGAGCGGACGGACAGGCTCGCCGATGCTGTGGTCTAA

Upstream 100 bases:

>100_bases
CGGGCGGGGGCGTGACGCTGCTCTCCGAGCCCGGCCCCGAATACGAGGAGACGCTGACCAAGGCGGCCCGCGTCTTCGCG
GCCTTCGAGGAGGAGGCGCC

Downstream 100 bases:

>100_bases
CGGGCGGCTGGTTGAGGGCGGCACCCTCCCCTTCGCCATGGGGGATCGTGGCCTGCTGCTCGGCGACGGCGTGTTCGACA
CCGCCCTGGCGATTCAGGGG

Product: glutamine amidotransferase

Products: NA

Alternate protein names: ADC synthase [H]

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MILVVDNYDSFVFNVVRYFEELGETVEVVRNDALDVAGIRARNPEAVVISPGPCTPAEAGVSLPAIRELSGEVPILGVCL
GHQAIGAAFGGRVERAGRPLHGHATPIRHGGERLFAGLPQPMQVGRYHSLIVAPTPEMERHLTVDAASGEGEVMALSHRS
HPTWGIQFHPESVLTENGHALFSNFLKEARAWRAAGASERTDRLADAVV

Sequences:

>Translated_209_residues
MILVVDNYDSFVFNVVRYFEELGETVEVVRNDALDVAGIRARNPEAVVISPGPCTPAEAGVSLPAIRELSGEVPILGVCL
GHQAIGAAFGGRVERAGRPLHGHATPIRHGGERLFAGLPQPMQVGRYHSLIVAPTPEMERHLTVDAASGEGEVMALSHRS
HPTWGIQFHPESVLTENGHALFSNFLKEARAWRAAGASERTDRLADAVV
>Mature_209_residues
MILVVDNYDSFVFNVVRYFEELGETVEVVRNDALDVAGIRARNPEAVVISPGPCTPAEAGVSLPAIRELSGEVPILGVCL
GHQAIGAAFGGRVERAGRPLHGHATPIRHGGERLFAGLPQPMQVGRYHSLIVAPTPEMERHLTVDAASGEGEVMALSHRS
HPTWGIQFHPESVLTENGHALFSNFLKEARAWRAAGASERTDRLADAVV

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=186, Percent_Identity=54.8387096774194, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1787517, Length=195, Percent_Identity=41.5384615384615, Blast_Score=139, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6322638, Length=208, Percent_Identity=37.9807692307692, Blast_Score=162, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=32.8571428571429, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 22495; Mature: 22495

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVVDNYDSFVFNVVRYFEELGETVEVVRNDALDVAGIRARNPEAVVISPGPCTPAEAG
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECCCCCCHHHCC
VSLPAIRELSGEVPILGVCLGHQAIGAAFGGRVERAGRPLHGHATPIRHGGERLFAGLPQ
CCCHHHHHHCCCCCEEEEECCCHHHHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHCCCCC
PMQVGRYHSLIVAPTPEMERHLTVDAASGEGEVMALSHRSHPTWGIQFHPESVLTENGHA
HHHCCCEEEEEEECCCCCHHEEEEEECCCCCCEEEEECCCCCCCEEEECCHHHHCCCCHH
LFSNFLKEARAWRAAGASERTDRLADAVV
HHHHHHHHHHHHHHCCCCHHHHHHHHHCC
>Mature Secondary Structure
MILVVDNYDSFVFNVVRYFEELGETVEVVRNDALDVAGIRARNPEAVVISPGPCTPAEAG
CEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCCEEEECCCCCCHHHCC
VSLPAIRELSGEVPILGVCLGHQAIGAAFGGRVERAGRPLHGHATPIRHGGERLFAGLPQ
CCCHHHHHHCCCCCEEEEECCCHHHHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHCCCCC
PMQVGRYHSLIVAPTPEMERHLTVDAASGEGEVMALSHRSHPTWGIQFHPESVLTENGHA
HHHCCCEEEEEEECCCCCHHEEEEEECCCCCCEEEEECCCCCCCEEEECCHHHHCCCCHH
LFSNFLKEARAWRAAGASERTDRLADAVV
HHHHHHHHHHHHHHCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3894673; 2403545; 11677609 [H]