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The map label for this gene is pabB [H]

Identifier: 218532164

GI number: 218532164

Start: 4512940

End: 4514340

Strand: Reverse

Name: pabB [H]

Synonym: Mchl_4276

Alternate gene names: 218532164

Gene position: 4514340-4512940 (Counterclockwise)

Preceding gene: 218532169

Following gene: 218532163

Centisome position: 78.13

GC content: 69.81

Gene sequence:

>1401_bases
ATGACGGCCGAGCCCATGGTCTGGACCCGCGAGATTCCCTTCATCGACCCGGTCGCGGCCGCGGCGCGGCTCGCCCGGCT
GCCCGGCCTCGCCTTCCTCGACAGCGCCATGCGGCACGATACGCTCGGCCGCGTCTCGGTGCTGGCTGCCGACCCGTTCG
CGCGGTTCCGCTACCGCGATGGTCGTGCCACCCTGGACGGGCGCGCGGTGCCCGGCTCGCCCATCGCGGCGTTGCGGGCC
TGCCTCGCACCCTACCGTCTGGCGCCCCGGCCCGACCTGCCCGCCATTCCGGGAGCGATCGGCTATTTCGCCTACGATCT
CGGCGCGAGCCTGGAGCGAGTCGCGGCCCCGGCGCGCCGGGCGGGGCTCACCGATGACATCGCCTTCAACCTCTACGACA
CCCTGCTCGCCGTCGATCATGGCCGCGGCACCTGCCTGCTGATCGCTACCGGCTTTCCCGAAGCCGATGGACCGGCCCGC
GCGGCACGGGCGCGGGCGCGGCTCGATGCCTTCGCCGATTGGCTCGCCGCCCCGTCCGAGCCGCTGCCGAAATGGACGGG
CGCCCGGCTCACATGGCGCTCGAATTTTTCGCGACAAACCTATGAAGCGGCTGTCGAAAAGGTCCGGGACTACATCCGTG
CCGGCGACATCTATCAGGCCAACATCGCCCAGCGTTTCGCCGCCGACCTGCCGCCCGGCTTCGACCCGTTCGCCTTCTAC
CGGAGGCTTCGCGAGACCAACCCGGCGACCTTCGGCGCCTATCTCGATTTCGAAGGGCTTACCGTCGCCTCCTCCTCGCC
CGAGCGCTTCCTCAAGTTGGAGGGGCGGGCGGTCGAGACGCGGCCGATCAAGGGCACCGTGGCCCGCGATCCCGATCCCG
CCCGCGATGCCGAGATCGCCGCCGCGCTCCAGGCCAATCCGAAGGAGCGGGCCGAGAACATCATGATCGTGGACCTGCTG
CGCAACGACCTGTCGCGGGTGTGCGAGCCGGGCAGCGTGCGGGTGCCGACCCTGTGCGGGCTGGAATCCTATGCCGGCAT
CCACCATCTCGTCTCAGTGGTGACGGGTACGCTGCGCGAGGGTTCGGATGCGCTCGACCTCATCCAGAAAACCTTTCCCG
GGGGCTCGATCACCGGCGCGCCGAAGCTCAGGGCCATGGATATCATCACCGAGATCGAGACGGATGCGCGCGAGCTCTAT
TGCGGGGCGATCGGCGCGCTTGGCTTCGACGGATCGCTCGACACCTCGATCGCGATCCGCACCGTGTTCATGGCGAAGGG
ACAGGCCGTGCTCCAGGCGGGCGGGGGCGTGACGCTGCTCTCCGAGCCCGGCCCCGAATACGAGGAGACGCTGACCAAGG
CGGCCCGCGTCTTCGCGGCCTTCGAGGAGGAGGCGCCATGA

Upstream 100 bases:

>100_bases
GCGCTGGCGCATACCCCGCCCGCGAGACCGGAACGCGGGGGCGATTGACGGGAGGGTGCCGCGCGCCCTTGGGTGAATCC
CAATGAGCGCCGCACGAGGC

Downstream 100 bases:

>100_bases
TCCTCGTCGTCGACAACTACGATTCCTTCGTCTTCAACGTGGTGCGCTACTTCGAGGAGTTGGGCGAGACCGTCGAGGTC
GTGCGCAACGACGCGCTCGA

Product: para-aminobenzoate synthase, subunit I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTAEPMVWTREIPFIDPVAAAARLARLPGLAFLDSAMRHDTLGRVSVLAADPFARFRYRDGRATLDGRAVPGSPIAALRA
CLAPYRLAPRPDLPAIPGAIGYFAYDLGASLERVAAPARRAGLTDDIAFNLYDTLLAVDHGRGTCLLIATGFPEADGPAR
AARARARLDAFADWLAAPSEPLPKWTGARLTWRSNFSRQTYEAAVEKVRDYIRAGDIYQANIAQRFAADLPPGFDPFAFY
RRLRETNPATFGAYLDFEGLTVASSSPERFLKLEGRAVETRPIKGTVARDPDPARDAEIAAALQANPKERAENIMIVDLL
RNDLSRVCEPGSVRVPTLCGLESYAGIHHLVSVVTGTLREGSDALDLIQKTFPGGSITGAPKLRAMDIITEIETDARELY
CGAIGALGFDGSLDTSIAIRTVFMAKGQAVLQAGGGVTLLSEPGPEYEETLTKAARVFAAFEEEAP

Sequences:

>Translated_466_residues
MTAEPMVWTREIPFIDPVAAAARLARLPGLAFLDSAMRHDTLGRVSVLAADPFARFRYRDGRATLDGRAVPGSPIAALRA
CLAPYRLAPRPDLPAIPGAIGYFAYDLGASLERVAAPARRAGLTDDIAFNLYDTLLAVDHGRGTCLLIATGFPEADGPAR
AARARARLDAFADWLAAPSEPLPKWTGARLTWRSNFSRQTYEAAVEKVRDYIRAGDIYQANIAQRFAADLPPGFDPFAFY
RRLRETNPATFGAYLDFEGLTVASSSPERFLKLEGRAVETRPIKGTVARDPDPARDAEIAAALQANPKERAENIMIVDLL
RNDLSRVCEPGSVRVPTLCGLESYAGIHHLVSVVTGTLREGSDALDLIQKTFPGGSITGAPKLRAMDIITEIETDARELY
CGAIGALGFDGSLDTSIAIRTVFMAKGQAVLQAGGGVTLLSEPGPEYEETLTKAARVFAAFEEEAP
>Mature_465_residues
TAEPMVWTREIPFIDPVAAAARLARLPGLAFLDSAMRHDTLGRVSVLAADPFARFRYRDGRATLDGRAVPGSPIAALRAC
LAPYRLAPRPDLPAIPGAIGYFAYDLGASLERVAAPARRAGLTDDIAFNLYDTLLAVDHGRGTCLLIATGFPEADGPARA
ARARARLDAFADWLAAPSEPLPKWTGARLTWRSNFSRQTYEAAVEKVRDYIRAGDIYQANIAQRFAADLPPGFDPFAFYR
RLRETNPATFGAYLDFEGLTVASSSPERFLKLEGRAVETRPIKGTVARDPDPARDAEIAAALQANPKERAENIMIVDLLR
NDLSRVCEPGSVRVPTLCGLESYAGIHHLVSVVTGTLREGSDALDLIQKTFPGGSITGAPKLRAMDIITEIETDARELYC
GAIGALGFDGSLDTSIAIRTVFMAKGQAVLQAGGGVTLLSEPGPEYEETLTKAARVFAAFEEEAP

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=450, Percent_Identity=38.4444444444444, Blast_Score=288, Evalue=5e-79,
Organism=Escherichia coli, GI1787518, Length=369, Percent_Identity=34.9593495934959, Blast_Score=196, Evalue=3e-51,
Organism=Escherichia coli, GI1786809, Length=229, Percent_Identity=26.2008733624454, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87082077, Length=213, Percent_Identity=27.6995305164319, Blast_Score=82, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6320935, Length=465, Percent_Identity=32.258064516129, Blast_Score=216, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6324361, Length=403, Percent_Identity=27.0471464019851, Blast_Score=143, Evalue=6e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 50233; Mature: 50101

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAEPMVWTREIPFIDPVAAAARLARLPGLAFLDSAMRHDTLGRVSVLAADPFARFRYRD
CCCCCCEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCHHHHEECC
GRATLDGRAVPGSPIAALRACLAPYRLAPRPDLPAIPGAIGYFAYDLGASLERVAAPARR
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCHHHH
AGLTDDIAFNLYDTLLAVDHGRGTCLLIATGFPEADGPARAARARARLDAFADWLAAPSE
CCCCHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
PLPKWTGARLTWRSNFSRQTYEAAVEKVRDYIRAGDIYQANIAQRFAADLPPGFDPFAFY
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCHHHHH
RRLRETNPATFGAYLDFEGLTVASSSPERFLKLEGRAVETRPIKGTVARDPDPARDAEIA
HHHHHCCCCEEEEEEECCCEEEECCCCHHHHEECCCEEECCCCCCCCCCCCCCCCHHHHH
AALQANPKERAENIMIVDLLRNDLSRVCEPGSVRVPTLCGLESYAGIHHLVSVVTGTLRE
HHHCCCCHHHHCCEEEHHHHHHHHHHHCCCCCEECCHHHCCHHHHHHHHHHHHHHHHHHC
GSDALDLIQKTFPGGSITGAPKLRAMDIITEIETDARELYCGAIGALGFDGSLDTSIAIR
CCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
TVFMAKGQAVLQAGGGVTLLSEPGPEYEETLTKAARVFAAFEEEAP
HHHHHCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TAEPMVWTREIPFIDPVAAAARLARLPGLAFLDSAMRHDTLGRVSVLAADPFARFRYRD
CCCCCEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCHHHHEECC
GRATLDGRAVPGSPIAALRACLAPYRLAPRPDLPAIPGAIGYFAYDLGASLERVAAPARR
CCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHCHHHH
AGLTDDIAFNLYDTLLAVDHGRGTCLLIATGFPEADGPARAARARARLDAFADWLAAPSE
CCCCHHHHHHHHHHHHEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
PLPKWTGARLTWRSNFSRQTYEAAVEKVRDYIRAGDIYQANIAQRFAADLPPGFDPFAFY
CCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCHHHHH
RRLRETNPATFGAYLDFEGLTVASSSPERFLKLEGRAVETRPIKGTVARDPDPARDAEIA
HHHHHCCCCEEEEEEECCCEEEECCCCHHHHEECCCEEECCCCCCCCCCCCCCCCHHHHH
AALQANPKERAENIMIVDLLRNDLSRVCEPGSVRVPTLCGLESYAGIHHLVSVVTGTLRE
HHHCCCCHHHHCCEEEHHHHHHHHHHHCCCCCEECCHHHCCHHHHHHHHHHHHHHHHHHC
GSDALDLIQKTFPGGSITGAPKLRAMDIITEIETDARELYCGAIGALGFDGSLDTSIAIR
CCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
TVFMAKGQAVLQAGGGVTLLSEPGPEYEETLTKAARVFAAFEEEAP
HHHHHCCCEEEECCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]