Click here to switch to the map view.

The map label for this gene is ilvE [H]

Identifier: 218532162

GI number: 218532162

Start: 4511470

End: 4512327

Strand: Reverse

Name: ilvE [H]

Synonym: Mchl_4274

Alternate gene names: 218532162

Gene position: 4512327-4511470 (Counterclockwise)

Preceding gene: 218532163

Following gene: 218532157

Centisome position: 78.1

GC content: 73.43

Gene sequence:

>858_bases
ATGCTGTGGTCTAACGGGCGGCTGGTTGAGGGCGGCACCCTCCCCTTCGCCATGGGGGATCGTGGCCTGCTGCTCGGCGA
CGGCGTGTTCGACACCGCCCTGGCGATTCAGGGGCAGGTCGCCTTCGAAGCCGCCCATGTTGATCGCCTCGCCGCCGCCG
CGGAAGCGCTCGGCTTCGCGATCGCGCGGGAGCGGATCGTCGAGGCGATGCGCGCGCTGGCCAGCACCGCGCCGCTCGCG
GCGATCCGCACGACGTTGACCCGCGGCCCCGGTCCGCGCGGGCTGGCGCCCCCGCCCGAGCCGAACCCGTTCCTGTTCGG
CAGCGCCGCCCCGGCCCGCGCCGCCCTGTTCTTCGCGCCCTTGCGGCTGGCGCTCACGGAGATTGCCCGCAACGAGACCT
CGCCGGCCGCGCGCCTCAAGACGCTGGGCTATCTCGACGCGGTGCTCGCCGCCCGCGCGGCGCAGGCGCAAGGCTTCGAC
GAGGCTCTGTTCCTGAACACGCGGGGCCGCGTCGCCTGCGCCGGCACCGGCAATGTCTTTGCGGTTTTCGGAGGGACGCT
CGTCACGCCGCCGCTGGAGGACGGCGTCCTGCCGGGTATCGTTCGGGCCGAGCTTGTTGCCAGGATCGCGCCGAGCCTCG
GCATCGCGGTCGAAGAGCGCCCTCTCCTGCCCTCGGAGCTGGCGGCGGCGGAGGCGCTGTTCGTCACCAACTCGCTGCGC
CTGCTCGCCCCCGTGAACGCGCTCGGTGCGCAGCCCTATGACAGCGCCGGGCACGGGACGGTTCGCAGCCTCTACGCGGC
TTTGCGGGAAACCGTGGCGGCGGAGTGCGGCGTCGAGGCGGACGCCCTCGACCCGTGA

Upstream 100 bases:

>100_bases
GTGCTGACCGAGAACGGCCACGCGCTGTTTTCCAACTTCCTGAAGGAGGCCCGTGCGTGGCGGGCGGCGGGCGCGTCGGA
GCGGACGGACAGGCTCGCCG

Downstream 100 bases:

>100_bases
TCCCGCCTTCCTGAAGCCACGGCCGTCCAGGCCCTCCCCTCATCCTGAGGTGCCCGCGCCAGCGGGCCTCGAAGGATCCT
CCAACTCGCGCGCGGTGCCT

Product: aminotransferase class IV

Products: NA

Alternate protein names: BCAT; Transaminase B [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MLWSNGRLVEGGTLPFAMGDRGLLLGDGVFDTALAIQGQVAFEAAHVDRLAAAAEALGFAIARERIVEAMRALASTAPLA
AIRTTLTRGPGPRGLAPPPEPNPFLFGSAAPARAALFFAPLRLALTEIARNETSPAARLKTLGYLDAVLAARAAQAQGFD
EALFLNTRGRVACAGTGNVFAVFGGTLVTPPLEDGVLPGIVRAELVARIAPSLGIAVEERPLLPSELAAAEALFVTNSLR
LLAPVNALGAQPYDSAGHGTVRSLYAALRETVAAECGVEADALDP

Sequences:

>Translated_285_residues
MLWSNGRLVEGGTLPFAMGDRGLLLGDGVFDTALAIQGQVAFEAAHVDRLAAAAEALGFAIARERIVEAMRALASTAPLA
AIRTTLTRGPGPRGLAPPPEPNPFLFGSAAPARAALFFAPLRLALTEIARNETSPAARLKTLGYLDAVLAARAAQAQGFD
EALFLNTRGRVACAGTGNVFAVFGGTLVTPPLEDGVLPGIVRAELVARIAPSLGIAVEERPLLPSELAAAEALFVTNSLR
LLAPVNALGAQPYDSAGHGTVRSLYAALRETVAAECGVEADALDP
>Mature_285_residues
MLWSNGRLVEGGTLPFAMGDRGLLLGDGVFDTALAIQGQVAFEAAHVDRLAAAAEALGFAIARERIVEAMRALASTAPLA
AIRTTLTRGPGPRGLAPPPEPNPFLFGSAAPARAALFFAPLRLALTEIARNETSPAARLKTLGYLDAVLAARAAQAQGFD
EALFLNTRGRVACAGTGNVFAVFGGTLVTPPLEDGVLPGIVRAELVARIAPSLGIAVEERPLLPSELAAAEALFVTNSLR
LLAPVNALGAQPYDSAGHGTVRSLYAALRETVAAECGVEADALDP

Specific function: Acts on leucine, isoleucine and valine [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787338, Length=260, Percent_Identity=29.2307692307692, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI48994963, Length=261, Percent_Identity=26.0536398467433, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005785 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 29379; Mature: 29379

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLWSNGRLVEGGTLPFAMGDRGLLLGDGVFDTALAIQGQVAFEAAHVDRLAAAAEALGFA
CCCCCCCEEECCCCCEEECCCCEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IARERIVEAMRALASTAPLAAIRTTLTRGPGPRGLAPPPEPNPFLFGSAAPARAALFFAP
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHH
LRLALTEIARNETSPAARLKTLGYLDAVLAARAAQAQGFDEALFLNTRGRVACAGTGNVF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCEE
AVFGGTLVTPPLEDGVLPGIVRAELVARIAPSLGIAVEERPLLPSELAAAEALFVTNSLR
EEECCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHCCHH
LLAPVNALGAQPYDSAGHGTVRSLYAALRETVAAECGVEADALDP
EEECHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MLWSNGRLVEGGTLPFAMGDRGLLLGDGVFDTALAIQGQVAFEAAHVDRLAAAAEALGFA
CCCCCCCEEECCCCCEEECCCCEEEECCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
IARERIVEAMRALASTAPLAAIRTTLTRGPGPRGLAPPPEPNPFLFGSAAPARAALFFAP
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHH
LRLALTEIARNETSPAARLKTLGYLDAVLAARAAQAQGFDEALFLNTRGRVACAGTGNVF
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEECCCCEE
AVFGGTLVTPPLEDGVLPGIVRAELVARIAPSLGIAVEERPLLPSELAAAEALFVTNSLR
EEECCEEECCCCCCCCCCHHHHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHHCCHH
LLAPVNALGAQPYDSAGHGTVRSLYAALRETVAAECGVEADALDP
EEECHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]