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The map label for this gene is sucD [H]

Identifier: 218532111

GI number: 218532111

Start: 4430648

End: 4431553

Strand: Reverse

Name: sucD [H]

Synonym: Mchl_4206

Alternate gene names: 218532111

Gene position: 4431553-4430648 (Counterclockwise)

Preceding gene: 218532112

Following gene: 218532099

Centisome position: 76.7

GC content: 71.3

Gene sequence:

>906_bases
ATGATCATCTACCGTCAGTCCGCCCGCGTCCTCGTCCAGGGCATCACGGGCAAGCAAGGCACCTTCTGGACGCAGAAGAT
GATGGAGTGCGGCACGCAGGTGGTCGCCGGCGTCAACCCGAAGCGTGCGGGCGAGCGGCATCTCGGCGTGCCGGTCTACG
CGACCGCCAAGGCGGCGATGGCCGAGAGCCCGTTCGACGTGGCGGTGATGTTCATCCCGCCGGCCATGGCCCGCGAGGCG
GCGCTCGACGCTATTCAAGCCGGCGCCCGCACCGTGGTGATCCTGACCGAGCACATCCCGGCCCGCGACGTGATGGCGAT
CCATCACGCGGCGGCGCAACACGGCACCCGAATCGTTGGCCCGAACACCGCCGGCATCGTGACGCCAGGCGAGGGGTTCG
TGGGCATCATGCCGGGGCACAACCCGAACATCTTCCAGCCGGGCGCGGTCGGCGTGATCTCGCGCTCGGGCAGCCTCGGG
ACGCTGATCTGCCTCAACCTCACCCGCGCCGGCCTCGGCCAGTCGGCCTTCCTCGGGATCGGCGGCGATCCGATGATCGG
CACGACGACCCGCGATGCGCTCCAGGCGCTCGACGAGGATGCGCGCACCCGCGCCGTGGTGCTCGTCGGCGAGATCGGCG
GGGCGATGGAGGAGGCAGCCGCCGACTACGCCGCCGGGATGTCGAAGCCGGTCGTGTCCTTCATCGCCGGGCGCGCCTCG
CCGCCGGGCAAGAAGATGGGCCATGCCGGCGCGATCGTGTCGGGGACTTTCGGCAGCTACGACGGCAAGCGCCGGGCGCT
GGAGGCGGCGGGCGTCGCGGTGGCCGACACGCCGGCCGAAATCCCGCGCCTGCTCGGCCTCGGCGAGACCCGGACAGGCT
CGGTCGCCCAGACACTTCAGGCCTGA

Upstream 100 bases:

>100_bases
TGCGCGAGGGACTCGGCTGCGAGCCCTTCGACCTGATGGAGGACGCGGTCCAGGCCGCCGTGGACGCCGCGCACTCGACT
GCGAGCCGGGGAGTCGCCCG

Downstream 100 bases:

>100_bases
CGCACGAAAAAGGCGCAGCGAGCCGTCGCGGCGCCTTCGATCCCGTGTCGGTGCGGGTTCAGACCCCGACGACGGTCCGG
AGATGGCCGAACAGCGCGGC

Product: CoA-binding protein

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MIIYRQSARVLVQGITGKQGTFWTQKMMECGTQVVAGVNPKRAGERHLGVPVYATAKAAMAESPFDVAVMFIPPAMAREA
ALDAIQAGARTVVILTEHIPARDVMAIHHAAAQHGTRIVGPNTAGIVTPGEGFVGIMPGHNPNIFQPGAVGVISRSGSLG
TLICLNLTRAGLGQSAFLGIGGDPMIGTTTRDALQALDEDARTRAVVLVGEIGGAMEEAAADYAAGMSKPVVSFIAGRAS
PPGKKMGHAGAIVSGTFGSYDGKRRALEAAGVAVADTPAEIPRLLGLGETRTGSVAQTLQA

Sequences:

>Translated_301_residues
MIIYRQSARVLVQGITGKQGTFWTQKMMECGTQVVAGVNPKRAGERHLGVPVYATAKAAMAESPFDVAVMFIPPAMAREA
ALDAIQAGARTVVILTEHIPARDVMAIHHAAAQHGTRIVGPNTAGIVTPGEGFVGIMPGHNPNIFQPGAVGVISRSGSLG
TLICLNLTRAGLGQSAFLGIGGDPMIGTTTRDALQALDEDARTRAVVLVGEIGGAMEEAAADYAAGMSKPVVSFIAGRAS
PPGKKMGHAGAIVSGTFGSYDGKRRALEAAGVAVADTPAEIPRLLGLGETRTGSVAQTLQA
>Mature_301_residues
MIIYRQSARVLVQGITGKQGTFWTQKMMECGTQVVAGVNPKRAGERHLGVPVYATAKAAMAESPFDVAVMFIPPAMAREA
ALDAIQAGARTVVILTEHIPARDVMAIHHAAAQHGTRIVGPNTAGIVTPGEGFVGIMPGHNPNIFQPGAVGVISRSGSLG
TLICLNLTRAGLGQSAFLGIGGDPMIGTTTRDALQALDEDARTRAVVLVGEIGGAMEEAAADYAAGMSKPVVSFIAGRAS
PPGKKMGHAGAIVSGTFGSYDGKRRALEAAGVAVADTPAEIPRLLGLGETRTGSVAQTLQA

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=282, Percent_Identity=43.9716312056738, Blast_Score=195, Evalue=3e-50,
Organism=Homo sapiens, GI38569423, Length=250, Percent_Identity=28.4, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI38569421, Length=250, Percent_Identity=28.4, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI1786949, Length=285, Percent_Identity=42.4561403508772, Blast_Score=234, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI17550194, Length=283, Percent_Identity=43.8162544169611, Blast_Score=210, Evalue=7e-55,
Organism=Caenorhabditis elegans, GI17553126, Length=286, Percent_Identity=41.958041958042, Blast_Score=210, Evalue=8e-55,
Organism=Caenorhabditis elegans, GI17557344, Length=247, Percent_Identity=27.9352226720648, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17551266, Length=247, Percent_Identity=27.5303643724696, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324716, Length=287, Percent_Identity=42.1602787456446, Blast_Score=200, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21356559, Length=283, Percent_Identity=42.756183745583, Blast_Score=224, Evalue=7e-59,
Organism=Drosophila melanogaster, GI28574296, Length=281, Percent_Identity=44.8398576512456, Blast_Score=209, Evalue=1e-54,
Organism=Drosophila melanogaster, GI281363477, Length=246, Percent_Identity=30.0813008130081, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281363475, Length=246, Percent_Identity=30.0813008130081, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281363473, Length=246, Percent_Identity=30.0813008130081, Blast_Score=89, Evalue=4e-18,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30869; Mature: 30869

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIYRQSARVLVQGITGKQGTFWTQKMMECGTQVVAGVNPKRAGERHLGVPVYATAKAAM
CEEEECCCEEEEEECCCCCCCHHHHHHHHCCHHEECCCCCCCCCCCCCCCCEEEHHHHHH
AESPFDVAVMFIPPAMAREAALDAIQAGARTVVILTEHIPARDVMAIHHAAAQHGTRIVG
CCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEC
PNTAGIVTPGEGFVGIMPGHNPNIFQPGAVGVISRSGSLGTLICLNLTRAGLGQSAFLGI
CCCCEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEEEEEHHHCCCCCCEEEEC
GGDPMIGTTTRDALQALDEDARTRAVVLVGEIGGAMEEAAADYAAGMSKPVVSFIAGRAS
CCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHCCCC
PPGKKMGHAGAIVSGTFGSYDGKRRALEAAGVAVADTPAEIPRLLGLGETRTGSVAQTLQ
CCCCCCCCCCCEEECCCCCCCCHHHHHHHCCEEEECCHHHHHHHHCCCCCCCCHHHHHHC
A
C
>Mature Secondary Structure
MIIYRQSARVLVQGITGKQGTFWTQKMMECGTQVVAGVNPKRAGERHLGVPVYATAKAAM
CEEEECCCEEEEEECCCCCCCHHHHHHHHCCHHEECCCCCCCCCCCCCCCCEEEHHHHHH
AESPFDVAVMFIPPAMAREAALDAIQAGARTVVILTEHIPARDVMAIHHAAAQHGTRIVG
CCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEC
PNTAGIVTPGEGFVGIMPGHNPNIFQPGAVGVISRSGSLGTLICLNLTRAGLGQSAFLGI
CCCCEEEECCCCEEEEECCCCCCCCCCCCEEEEECCCCCEEEEEEEHHHCCCCCCEEEEC
GGDPMIGTTTRDALQALDEDARTRAVVLVGEIGGAMEEAAADYAAGMSKPVVSFIAGRAS
CCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHCCCC
PPGKKMGHAGAIVSGTFGSYDGKRRALEAAGVAVADTPAEIPRLLGLGETRTGSVAQTLQ
CCCCCCCCCCCEEECCCCCCCCHHHHHHHCCEEEECCHHHHHHHHCCCCCCCCHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]