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The map label for this gene is murA

Identifier: 218710664

GI number: 218710664

Start: 2911779

End: 2913047

Strand: Reverse

Name: murA

Synonym: VS_2744

Alternate gene names: 218710664

Gene position: 2913047-2911779 (Counterclockwise)

Preceding gene: 218710665

Following gene: 218710663

Centisome position: 88.29

GC content: 47.04

Gene sequence:

>1269_bases
ATGATGGAAAAGTTTCGAGTTATTGGATCGGATAAGCCGCTAAGCGGTGAAGTGACGATCTCAGGCGCAAAAAATGCAGC
CCTACCAATCCTATTTGCTTCAATTCTAGCTGAAGAGCCGGTTGAAGTGAGTAATGTTCCTCACCTACGTGACATCGATA
CTACGATGGAATTGCTTAAGCGTTTAGGCGCAAAAGTATCACGCAACGGTAGTGTTCATGTTGATGGCCGCGAAATTAAT
GAATTTTGTGCACCTTACGATTTAGTAAAAACAATGCGCGCTTCTATCTGGGCTTTAGGTCCTTTAGTCGCTCGTTTTGG
TGAAGGCCAAGTGTCACTTCCGGGCGGTTGTGCAATTGGTGCTCGACCTGTTGATTTACATATCCATGGCCTAGAGCAAC
TAGGTGCGACCATTGTATTGGAAGATGGTTATGTGAAAGCAAGTGTTGATGGCCGTCTGAAAGGCGCGCACATCGTGATG
GATAAAGTAAGTGTGGGTGCCACCATTACTATCATGTGTGCAGCAACATTGGCTGAAGGTACAACTGTATTAGATAACTC
AGCGCGAGAGCCTGAGATTGTTGATACGGCTGATTTCCTAAACAAACTGGGTGCTAAGATTTCTGGCGCAGGTACAGACA
CGATCACTATCGAAGGCGTTGAGCGTCTTGGTGGTGGCCAACACTCTGTGGTTGCTGACCGTATTGAAACCGGTACGTTC
TTGGTTGCTGCGGCAGTGTCTGGCGGTAAAGTGGTTTGTCGCAACACCAACGCTCATCTTCTTGAAGCTGCATTAGCGAA
GCTTGAAGAAGCGGGTGCGAAGGTTGAAACGGGCGAAGGTTGGATCAGCCTTGATATGACAGATCGTGAGCTGAAAGCGG
TGAAAATCGTAACAGCACCTCACCCAGGTTTCCCAACCGACATGCAAGCACAGTTTACTCTGCTCAACATGATGGCGAAG
GGCAGTGGTGTTATCACTGAGACTATCTTTGAAAACCGCTTTATGCACATTCCTGAGTTACAGCGAATGGGCGCAAAAGC
GGAAATCGAAGGCAACACGGCTATTTGTGGTGAAACTGAGAAGTTAAGCGGCGCTCAAGTAATGGCAACGGATCTTCGTG
CATCTGCGAGTCTAGTTATTGCTGGTTGTATTGCCCAAGGCGAAACTATCGTTGACCGTATTTATCACATCGATCGTGGC
TACGATAAGATTGAAGATAAACTTTCAGCTTTAGGCGCAAACATTACACGATTTAGCGAGTCGAACTAA

Upstream 100 bases:

>100_bases
TGGAATACATTCAACGCAATGATATCCATGCTCTTTCTATTAAGGCTTTCACGCCGGAAGAGTGGGAACGTGATAAGAAA
CTGATGTCACTTTAAGGTTT

Downstream 100 bases:

>100_bases
CTTAGGTTAGTGGATTCATGAATCAGTAAGATGAAAACATAAAAGTCGGAACCTTGGTTTCGGCTTTTTTATAGTTGTAT
TTACCGCAAGTGAGTCTATT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MMEKFRVIGSDKPLSGEVTISGAKNAALPILFASILAEEPVEVSNVPHLRDIDTTMELLKRLGAKVSRNGSVHVDGREIN
EFCAPYDLVKTMRASIWALGPLVARFGEGQVSLPGGCAIGARPVDLHIHGLEQLGATIVLEDGYVKASVDGRLKGAHIVM
DKVSVGATITIMCAATLAEGTTVLDNSAREPEIVDTADFLNKLGAKISGAGTDTITIEGVERLGGGQHSVVADRIETGTF
LVAAAVSGGKVVCRNTNAHLLEAALAKLEEAGAKVETGEGWISLDMTDRELKAVKIVTAPHPGFPTDMQAQFTLLNMMAK
GSGVITETIFENRFMHIPELQRMGAKAEIEGNTAICGETEKLSGAQVMATDLRASASLVIAGCIAQGETIVDRIYHIDRG
YDKIEDKLSALGANITRFSESN

Sequences:

>Translated_422_residues
MMEKFRVIGSDKPLSGEVTISGAKNAALPILFASILAEEPVEVSNVPHLRDIDTTMELLKRLGAKVSRNGSVHVDGREIN
EFCAPYDLVKTMRASIWALGPLVARFGEGQVSLPGGCAIGARPVDLHIHGLEQLGATIVLEDGYVKASVDGRLKGAHIVM
DKVSVGATITIMCAATLAEGTTVLDNSAREPEIVDTADFLNKLGAKISGAGTDTITIEGVERLGGGQHSVVADRIETGTF
LVAAAVSGGKVVCRNTNAHLLEAALAKLEEAGAKVETGEGWISLDMTDRELKAVKIVTAPHPGFPTDMQAQFTLLNMMAK
GSGVITETIFENRFMHIPELQRMGAKAEIEGNTAICGETEKLSGAQVMATDLRASASLVIAGCIAQGETIVDRIYHIDRG
YDKIEDKLSALGANITRFSESN
>Mature_422_residues
MMEKFRVIGSDKPLSGEVTISGAKNAALPILFASILAEEPVEVSNVPHLRDIDTTMELLKRLGAKVSRNGSVHVDGREIN
EFCAPYDLVKTMRASIWALGPLVARFGEGQVSLPGGCAIGARPVDLHIHGLEQLGATIVLEDGYVKASVDGRLKGAHIVM
DKVSVGATITIMCAATLAEGTTVLDNSAREPEIVDTADFLNKLGAKISGAGTDTITIEGVERLGGGQHSVVADRIETGTF
LVAAAVSGGKVVCRNTNAHLLEAALAKLEEAGAKVETGEGWISLDMTDRELKAVKIVTAPHPGFPTDMQAQFTLLNMMAK
GSGVITETIFENRFMHIPELQRMGAKAEIEGNTAICGETEKLSGAQVMATDLRASASLVIAGCIAQGETIVDRIYHIDRG
YDKIEDKLSALGANITRFSESN

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily

Homologues:

Organism=Escherichia coli, GI1789580, Length=416, Percent_Identity=77.8846153846154, Blast_Score=671, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURA_VIBSL (B7VKU1)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002418285.1
- GeneID:   7162233
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2744
- HOGENOM:   HBG482701
- OMA:   MVKTMRA
- ProtClustDB:   PRK09369
- GO:   GO:0005737
- HAMAP:   MF_00111
- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750
- Gene3D:   G3DSA:3.65.10.10
- PANTHER:   PTHR21090:SF4
- TIGRFAMs:   TIGR01072

Pfam domain/function: PF00275 EPSP_synthase; SSF55205 RNA3'_cycl/enolpyr_transf_A/B

EC number: =2.5.1.7

Molecular weight: Translated: 44716; Mature: 44716

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: ACT_SITE 117-117

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEKFRVIGSDKPLSGEVTISGAKNAALPILFASILAEEPVEVSNVPHLRDIDTTMELLK
CCCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
RLGAKVSRNGSVHVDGREINEFCAPYDLVKTMRASIWALGPLVARFGEGQVSLPGGCAIG
HHCCCCCCCCCEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCC
ARPVDLHIHGLEQLGATIVLEDGYVKASVDGRLKGAHIVMDKVSVGATITIMCAATLAEG
CEEEEEEEECHHHCCCEEEEECCEEEEECCCCCCCEEEEEEEECCCCEEEEEEEEHHHCC
TTVLDNSAREPEIVDTADFLNKLGAKISGAGTDTITIEGVERLGGGQHSVVADRIETGTF
CEEECCCCCCCCCCCHHHHHHHHCCEEECCCCCEEEEEEHHHCCCCCCCHHHHHHCCCEE
LVAAAVSGGKVVCRNTNAHLLEAALAKLEEAGAKVETGEGWISLDMTDRELKAVKIVTAP
EEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCEEEEEEEECC
HPGFPTDMQAQFTLLNMMAKGSGVITETIFENRFMHIPELQRMGAKAEIEGNTAICGETE
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHCCCCEEECCCEEECCCCC
KLSGAQVMATDLRASASLVIAGCIAQGETIVDRIYHIDRGYDKIEDKLSALGANITRFSE
CCCCCEEEEHHHHCCCEEEEEEHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEECCC
SN
CC
>Mature Secondary Structure
MMEKFRVIGSDKPLSGEVTISGAKNAALPILFASILAEEPVEVSNVPHLRDIDTTMELLK
CCCCEEEECCCCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
RLGAKVSRNGSVHVDGREINEFCAPYDLVKTMRASIWALGPLVARFGEGQVSLPGGCAIG
HHCCCCCCCCCEEECCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCC
ARPVDLHIHGLEQLGATIVLEDGYVKASVDGRLKGAHIVMDKVSVGATITIMCAATLAEG
CEEEEEEEECHHHCCCEEEEECCEEEEECCCCCCCEEEEEEEECCCCEEEEEEEEHHHCC
TTVLDNSAREPEIVDTADFLNKLGAKISGAGTDTITIEGVERLGGGQHSVVADRIETGTF
CEEECCCCCCCCCCCHHHHHHHHCCEEECCCCCEEEEEEHHHCCCCCCCHHHHHHCCCEE
LVAAAVSGGKVVCRNTNAHLLEAALAKLEEAGAKVETGEGWISLDMTDRELKAVKIVTAP
EEEEECCCCEEEEECCCHHHHHHHHHHHHHCCCEEECCCCEEEEECCCCCEEEEEEEECC
HPGFPTDMQAQFTLLNMMAKGSGVITETIFENRFMHIPELQRMGAKAEIEGNTAICGETE
CCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCHHHHCCCCEEECCCEEECCCCC
KLSGAQVMATDLRASASLVIAGCIAQGETIVDRIYHIDRGYDKIEDKLSALGANITRFSE
CCCCCEEEEHHHHCCCEEEEEEHHHCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCEECCC
SN
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA