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The map label for this gene is glsA

Identifier: 218710636

GI number: 218710636

Start: 2876315

End: 2877235

Strand: Reverse

Name: glsA

Synonym: VS_2690

Alternate gene names: 218710636

Gene position: 2877235-2876315 (Counterclockwise)

Preceding gene: 218710637

Following gene: 218710628

Centisome position: 87.21

GC content: 45.39

Gene sequence:

>921_bases
ATGAAACCAACTCAAGCTATTTTGGCCGAGATTTTAGATGAAGTTCGCCCTTTAATTGGTCAGGGAAAGGTCGCTGATTA
TATTCCTGCATTGGCTCGTGTATCGAACCAGAAATTGGCGATTGCGGTATACACCAATGAAGGTGAAGTCATTCAAGCTG
GCGATGCTGATGAAGCCTTTTCCGTGCAATCAATCTCTAAAGCTTTAAGCCTGACGTTGGCGATGGTGTTGTATAAGCCG
GAAGAAATTTGGCAACGCGTTGGAAAGGAACCTTCAGGACAAGCCTTTAACTCGATGATTCAGCTTGAGATGGAACACGG
CATCCCTCGTAACCCGTTTATTAATGCTGGCGCGATTGTCGTTGCTGACTTATTACAAAGCCGTTTATCAGCACCAAGAC
ACCGTTTATTAGAATTTGTCCGTCAGCTATCAGGTGATACACATATCGTGTATGACAAGGTTGTGGCAGCTTCTGAGATG
ATGCACAGCGATCGTAATGCTGCTATCGCTTATTTGATGCGTTCATTTGGTAATTTTGAGAACGATGTTATCCCCGTACT
CAACAATTACTTTCATGCTTGTGCGCTTAAAATGACCTGTGTTGACTTGGCGAAGACCTTTAGCTATTTGGCAAACAAAG
GTGTGTCTGTTCAGACTAAGAAAGAGATCATCACGCCAGTTCAAACCAAACAGCTGAATGCTTTGCTTGCGACATGTGGT
TTGTACGATGGGGCGGGAGAGTTTGCCTATCGTGTTGGTATGCCGGGTAAATCGGGTGTTGGCGGTGGGATTATTGCGAT
TGTTCCTGGCGAAATGACGATCGCGGTGTGGTCTCCAGAGTTGGATGCATCGGGTAATTCACTGGCGGGAACTCAGGCTT
TAGAATTACTCTCAGAGCGTATTGGTCGCTCTATTTTCTAA

Upstream 100 bases:

>100_bases
GTTGGCTTTTTTGTCCTTAGGCTTTTATTGCGATAAAGGTTTAAGGACAGAAAGTAATGTCGTACCCCCTACAAAAATAA
CAATAAAGAAGTAAGCACAC

Downstream 100 bases:

>100_bases
GTTCTAAGTTCGACAAAAAAAGCCTCTCGTGATGAGAGACTTTTTGCATTCTAGCGTTCGAACTATTCGTCTTCTTCTGC
CATAAAGGCTTCAAGCAAAT

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MKPTQAILAEILDEVRPLIGQGKVADYIPALARVSNQKLAIAVYTNEGEVIQAGDADEAFSVQSISKALSLTLAMVLYKP
EEIWQRVGKEPSGQAFNSMIQLEMEHGIPRNPFINAGAIVVADLLQSRLSAPRHRLLEFVRQLSGDTHIVYDKVVAASEM
MHSDRNAAIAYLMRSFGNFENDVIPVLNNYFHACALKMTCVDLAKTFSYLANKGVSVQTKKEIITPVQTKQLNALLATCG
LYDGAGEFAYRVGMPGKSGVGGGIIAIVPGEMTIAVWSPELDASGNSLAGTQALELLSERIGRSIF

Sequences:

>Translated_306_residues
MKPTQAILAEILDEVRPLIGQGKVADYIPALARVSNQKLAIAVYTNEGEVIQAGDADEAFSVQSISKALSLTLAMVLYKP
EEIWQRVGKEPSGQAFNSMIQLEMEHGIPRNPFINAGAIVVADLLQSRLSAPRHRLLEFVRQLSGDTHIVYDKVVAASEM
MHSDRNAAIAYLMRSFGNFENDVIPVLNNYFHACALKMTCVDLAKTFSYLANKGVSVQTKKEIITPVQTKQLNALLATCG
LYDGAGEFAYRVGMPGKSGVGGGIIAIVPGEMTIAVWSPELDASGNSLAGTQALELLSERIGRSIF
>Mature_306_residues
MKPTQAILAEILDEVRPLIGQGKVADYIPALARVSNQKLAIAVYTNEGEVIQAGDADEAFSVQSISKALSLTLAMVLYKP
EEIWQRVGKEPSGQAFNSMIQLEMEHGIPRNPFINAGAIVVADLLQSRLSAPRHRLLEFVRQLSGDTHIVYDKVVAASEM
MHSDRNAAIAYLMRSFGNFENDVIPVLNNYFHACALKMTCVDLAKTFSYLANKGVSVQTKKEIITPVQTKQLNALLATCG
LYDGAGEFAYRVGMPGKSGVGGGIIAIVPGEMTIAVWSPELDASGNSLAGTQALELLSERIGRSIF

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family

Homologues:

Organism=Homo sapiens, GI156104878, Length=273, Percent_Identity=35.8974358974359, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI20336214, Length=291, Percent_Identity=32.6460481099656, Blast_Score=164, Evalue=8e-41,
Organism=Escherichia coli, GI1787804, Length=301, Percent_Identity=66.4451827242525, Blast_Score=424, Evalue=1e-120,
Organism=Escherichia coli, GI1786693, Length=286, Percent_Identity=38.8111888111888, Blast_Score=198, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17507019, Length=298, Percent_Identity=37.9194630872483, Blast_Score=194, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI17532727, Length=291, Percent_Identity=36.426116838488, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI193204073, Length=279, Percent_Identity=36.5591397849462, Blast_Score=174, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI193204075, Length=281, Percent_Identity=35.9430604982206, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI281363241, Length=290, Percent_Identity=34.8275862068965, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24653164, Length=290, Percent_Identity=34.8275862068965, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24653162, Length=290, Percent_Identity=34.8275862068965, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI281363239, Length=290, Percent_Identity=34.8275862068965, Blast_Score=184, Evalue=5e-47,
Organism=Drosophila melanogaster, GI24653158, Length=290, Percent_Identity=34.8275862068965, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24653156, Length=290, Percent_Identity=34.8275862068965, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=34.7368421052632, Blast_Score=184, Evalue=6e-47,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=34.7368421052632, Blast_Score=184, Evalue=7e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLSA_VIBSL (B7VKR3)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002418257.1
- ProteinModelPortal:   B7VKR3
- SMR:   B7VKR3
- GeneID:   7162205
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_2690
- HOGENOM:   HBG512335
- OMA:   RNASIAY
- ProtClustDB:   PRK00971
- HAMAP:   MF_00313
- InterPro:   IPR012338
- InterPro:   IPR015868
- Gene3D:   G3DSA:3.40.710.20
- PANTHER:   PTHR12544
- TIGRFAMs:   TIGR03814

Pfam domain/function: PF04960 Glutaminase; SSF56601 PBP_transp_fold

EC number: =3.5.1.2

Molecular weight: Translated: 33113; Mature: 33113

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPTQAILAEILDEVRPLIGQGKVADYIPALARVSNQKLAIAVYTNEGEVIQAGDADEAF
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCCCCHH
SVQSISKALSLTLAMVLYKPEEIWQRVGKEPSGQAFNSMIQLEMEHGIPRNPFINAGAIV
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHH
VADLLQSRLSAPRHRLLEFVRQLSGDTHIVYDKVVAASEMMHSDRNAAIAYLMRSFGNFE
HHHHHHHHHCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
NDVIPVLNNYFHACALKMTCVDLAKTFSYLANKGVSVQTKKEIITPVQTKQLNALLATCG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHC
LYDGAGEFAYRVGMPGKSGVGGGIIAIVPGEMTIAVWSPELDASGNSLAGTQALELLSER
CCCCCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
IGRSIF
HCCCCC
>Mature Secondary Structure
MKPTQAILAEILDEVRPLIGQGKVADYIPALARVSNQKLAIAVYTNEGEVIQAGDADEAF
CCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCCCCHH
SVQSISKALSLTLAMVLYKPEEIWQRVGKEPSGQAFNSMIQLEMEHGIPRNPFINAGAIV
HHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHH
VADLLQSRLSAPRHRLLEFVRQLSGDTHIVYDKVVAASEMMHSDRNAAIAYLMRSFGNFE
HHHHHHHHHCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHCCCC
NDVIPVLNNYFHACALKMTCVDLAKTFSYLANKGVSVQTKKEIITPVQTKQLNALLATCG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHCCCHHHHHHHHHHHHC
LYDGAGEFAYRVGMPGKSGVGGGIIAIVPGEMTIAVWSPELDASGNSLAGTQALELLSER
CCCCCCCCEEEECCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
IGRSIF
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA