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The map label for this gene is cbiC [H]

Identifier: 218710608

GI number: 218710608

Start: 2849004

End: 2849663

Strand: Direct

Name: cbiC [H]

Synonym: VS_2662

Alternate gene names: 218710608

Gene position: 2849004-2849663 (Clockwise)

Preceding gene: 218710607

Following gene: 218710609

Centisome position: 86.35

GC content: 45.3

Gene sequence:

>660_bases
ATGACTAACGATATGCGTCAAATGACCAAGCAAGGCCGTCAAATTGAAAGTGACTCTTTCTCTATCATTGATGAAGAAAT
AGAAACTCTCCATGGGGGACATAACTTCAATCAAGGTGAATGGAATGTGGTTCGTCGTGCCATTCATACTACGGGTGATT
TTGAATACGCTAAATTATATCAATTCAGCGACAACGCGATTGAGTCTGCCATTACCGCTTTAAAAAACGGTGCCAACATC
ATTACCGATGTCAGCATGATCGTGACAGGTTTAAACCAAACTCGCCTCAACGCTTACGGCAATAAAGCACAGTGCTTCAT
TAGTCATCCAGACGTCATTAGCACGGCTAAAGAGACAGGAGAAACACGTGCTATTCACTCAATGCGTTATGCCCGCGATA
ACGGCCTACTCGACGGCTCTATCATAGGTGTAGGCAATGCGCCTACCGCATTACTTGAGCTATTGCGCATGATTGAGGCA
GGAGAAGCCAAACCCGCACTGATCATCGGTATTCCTGTTGGCTTTGTAAAAGCAGATGAATCTAAGCAAGCATTAACCGA
ACAAAACACAGTGCCTTACATTGCCAGCCTAGGCCGTAAAGGTGGCAGCCCGTTAGTGGTATCGACTATTCACGCCCTAC
TTGCTGAGTCAGTAAAATGA

Upstream 100 bases:

>100_bases
TCGATTTTAACGGCGATCTATTAGCAGAACATCTCTGCTCAAAAGGAAGTGATACCAACACTCACTTTCATGATGAATAA
GCATGAACAAGGAAAACTCC

Downstream 100 bases:

>100_bases
ATAATGTAAGTACTCACTCTCAGCTTATCGATTGCTATCAAACGGCCATCACGGTAGTCGGAGTACCCGAAGATGGGTGT
TTAAGCCTAACCAGTCGAGC

Product: precorrin-8X methylmutase CbiC

Products: hydrogenobyrinate

Alternate protein names: Cobalt-precorrin isomerase; HBA synthase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MTNDMRQMTKQGRQIESDSFSIIDEEIETLHGGHNFNQGEWNVVRRAIHTTGDFEYAKLYQFSDNAIESAITALKNGANI
ITDVSMIVTGLNQTRLNAYGNKAQCFISHPDVISTAKETGETRAIHSMRYARDNGLLDGSIIGVGNAPTALLELLRMIEA
GEAKPALIIGIPVGFVKADESKQALTEQNTVPYIASLGRKGGSPLVVSTIHALLAESVK

Sequences:

>Translated_219_residues
MTNDMRQMTKQGRQIESDSFSIIDEEIETLHGGHNFNQGEWNVVRRAIHTTGDFEYAKLYQFSDNAIESAITALKNGANI
ITDVSMIVTGLNQTRLNAYGNKAQCFISHPDVISTAKETGETRAIHSMRYARDNGLLDGSIIGVGNAPTALLELLRMIEA
GEAKPALIIGIPVGFVKADESKQALTEQNTVPYIASLGRKGGSPLVVSTIHALLAESVK
>Mature_218_residues
TNDMRQMTKQGRQIESDSFSIIDEEIETLHGGHNFNQGEWNVVRRAIHTTGDFEYAKLYQFSDNAIESAITALKNGANII
TDVSMIVTGLNQTRLNAYGNKAQCFISHPDVISTAKETGETRAIHSMRYARDNGLLDGSIIGVGNAPTALLELLRMIEAG
EAKPALIIGIPVGFVKADESKQALTEQNTVPYIASLGRKGGSPLVVSTIHALLAESVK

Specific function: Catalyzes the conversion of cobalt-precorrin-8X to cobyrinic acid; a methyl migration reaction during the transformation of cobalt-precorrin-3 to form cobyrinic acid [H]

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003722 [H]

Pfam domain/function: PF02570 CbiC [H]

EC number: 5.4.1.2

Molecular weight: Translated: 23757; Mature: 23626

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNDMRQMTKQGRQIESDSFSIIDEEIETLHGGHNFNQGEWNVVRRAIHTTGDFEYAKLY
CCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHE
QFSDNAIESAITALKNGANIITDVSMIVTGLNQTRLNAYGNKAQCFISHPDVISTAKETG
ECCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCHHHHHHHHCC
ETRAIHSMRYARDNGLLDGSIIGVGNAPTALLELLRMIEAGEAKPALIIGIPVGFVKADE
HHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCC
SKQALTEQNTVPYIASLGRKGGSPLVVSTIHALLAESVK
HHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNDMRQMTKQGRQIESDSFSIIDEEIETLHGGHNFNQGEWNVVRRAIHTTGDFEYAKLY
CCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHE
QFSDNAIESAITALKNGANIITDVSMIVTGLNQTRLNAYGNKAQCFISHPDVISTAKETG
ECCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCHHHHHHHHCC
ETRAIHSMRYARDNGLLDGSIIGVGNAPTALLELLRMIEAGEAKPALIIGIPVGFVKADE
HHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCEEEEECCCCEEECCC
SKQALTEQNTVPYIASLGRKGGSPLVVSTIHALLAESVK
HHHHHHHCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]