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The map label for this gene is ptsG [H]

Identifier: 218710596

GI number: 218710596

Start: 2834835

End: 2836403

Strand: Reverse

Name: ptsG [H]

Synonym: VS_2649

Alternate gene names: 218710596

Gene position: 2836403-2834835 (Counterclockwise)

Preceding gene: 218710597

Following gene: 218710595

Centisome position: 85.97

GC content: 41.56

Gene sequence:

>1569_bases
TTGATAAAGTTCGTTGGTATTCTAACGATATTAAAGGACTTTATTATGCTAGATAGTTTTAAAAGCGGCTTATCTAAGCT
TTCCTTAATTGGTAAAGCATTGATGTTGCCCATATCTATATTACCCGCAGCGGGGTTATTACTTGCCTTCGGTGCTAAGC
TCGACATTCCCCTAATGATGCGTGCTGGTGGCGTTATATTTGATAACTTAGCCTTACTGTTTGCGGTAGGAGCCGCGGTT
GGTTTGACTAAGGAGTCAGGGATTGCCGCTTTAGCCGCGATTGTCGCCATGGTCGTGATGAATGCGACAATGGGGGTGGC
GCTCGGCATTACACCTGAGATGGCGATGGGAGGTGGCCGTTATGCAATGGTGATGGGTATTCCTTCATTGCAAACAGGTG
TATTTGGCGGACTCATTGCAGGTATCCTCGCAGCCGTTATGTATCAACGTTTCTATGATACTAAGCTGCCTGATTTCCTT
GGTTTCTTTGCCGGTAAACGCTTTGTACCGATTGTGACTGCGTTTTCTGCATTCCTAATTGGTTTAGTTTTACCCCATAT
TTGGTCATATATTCAATCAGGTATTGATGCGCTATCGCATATGGCGAATGGCGGAAACATGTACGTATCAACTTTCATCT
ACGGATTTATGGAGCGCGCTTTAATTCCAGTTGGTCTCCATCATATTTTTTATAGCCCTTATTGGTTTTCTTTCGGTGAG
TACACAACTGCCGCGGGTACCATTGTAAATGGCGATCATACCATTTGGTTTAAAATGCTTGAAGATGGAGTAAAAACGTT
CTCAACCAGTGAATACCAAGAAGCAGGAAAATTCCTATCGGGTAATTTTGCTATCTACATGTTTGCTTTCCCTGCAGCAT
GTTTAGCTATGTATCATGAAGCGAATGATAAAAATAAAAAAATTGCAGCAGGTATTTTAGGCTCTGCTGCTCTTACTTCT
TTTGTTACAGGTATAACAGAACCCGTTGAATTTGCTTTTATCTTTGTCGCACCTTTACTTTATGTTTTTTCTGCAATCAT
GGCAGGGGTGTCTTACGCGGTGACTTATGCGTTGGATGTTCATATTGGTAAAACCTTCTCAGCCGGCATTATTGATTTCG
TGTCTTTTGGTGTTCTTCCCGCGATGGATGGGTTCAAAACTAACTGGATCAATGTGATTCTTTGGGGGCTAACCATGGCC
GCTATTTATTACACGGTTTTCCGTTTTGCTATTCGAAAGTTCAATTTGAAAACAGTAGGACGTGAGGATACTCAAAGTAA
GGCGATCACTTTGGACAATGAAGATTTAGCTAGTGAAATCACAATCTTGATTGGTGGTGCCGCTAACATTACTTCGATAG
GAGCATGTATTACGAGATTGCGTTTACAGATTAAAGATCAGGCTCTTGTGAATGAACAAGGAATCAAAGACCTAGGTGCT
ATGGGAGTTATAAAAGTAGGTTCAAATGGATTGCAAATTATTTTGGGCTCAAGAGCTCAATTTGTGGCTGATCTTATGAG
TGAAAGAACTGGTGAGTCACCAAGTGCACTATCAACTAATCCAAGTTAA

Upstream 100 bases:

>100_bases
CTAGAAATTACTATGTACCTTCGACATTTTCCAGCCTAGGTCTATTGTAAAAAACGAGTTACAAACTACTTGCTATTTGT
AACCTTGAGATTCAATTAGC

Downstream 100 bases:

>100_bases
AAGCACGGGCTACTTCCGATAAAGCTGGTGGCAACAAGCTTGTTGTCTCTGATACATAAATAATAACGCTATCAACGCTA
TGGTTGGTGGCGTTTATTTG

Product: PTS system glucose-specific transporter subunit EIICBA

Products: NA

Alternate protein names: EIICBA-Glc; EII-Glc; Glucose permease IIC component; PTS system glucose-specific EIIC component; Glucose-specific phosphotransferase enzyme IIB component; PTS system glucose-specific EIIB component; Glucose-specific phosphotransferase enzyme IIA component; PTS system glucose-specific EIIA component [H]

Number of amino acids: Translated: 522; Mature: 522

Protein sequence:

>522_residues
MIKFVGILTILKDFIMLDSFKSGLSKLSLIGKALMLPISILPAAGLLLAFGAKLDIPLMMRAGGVIFDNLALLFAVGAAV
GLTKESGIAALAAIVAMVVMNATMGVALGITPEMAMGGGRYAMVMGIPSLQTGVFGGLIAGILAAVMYQRFYDTKLPDFL
GFFAGKRFVPIVTAFSAFLIGLVLPHIWSYIQSGIDALSHMANGGNMYVSTFIYGFMERALIPVGLHHIFYSPYWFSFGE
YTTAAGTIVNGDHTIWFKMLEDGVKTFSTSEYQEAGKFLSGNFAIYMFAFPAACLAMYHEANDKNKKIAAGILGSAALTS
FVTGITEPVEFAFIFVAPLLYVFSAIMAGVSYAVTYALDVHIGKTFSAGIIDFVSFGVLPAMDGFKTNWINVILWGLTMA
AIYYTVFRFAIRKFNLKTVGREDTQSKAITLDNEDLASEITILIGGAANITSIGACITRLRLQIKDQALVNEQGIKDLGA
MGVIKVGSNGLQIILGSRAQFVADLMSERTGESPSALSTNPS

Sequences:

>Translated_522_residues
MIKFVGILTILKDFIMLDSFKSGLSKLSLIGKALMLPISILPAAGLLLAFGAKLDIPLMMRAGGVIFDNLALLFAVGAAV
GLTKESGIAALAAIVAMVVMNATMGVALGITPEMAMGGGRYAMVMGIPSLQTGVFGGLIAGILAAVMYQRFYDTKLPDFL
GFFAGKRFVPIVTAFSAFLIGLVLPHIWSYIQSGIDALSHMANGGNMYVSTFIYGFMERALIPVGLHHIFYSPYWFSFGE
YTTAAGTIVNGDHTIWFKMLEDGVKTFSTSEYQEAGKFLSGNFAIYMFAFPAACLAMYHEANDKNKKIAAGILGSAALTS
FVTGITEPVEFAFIFVAPLLYVFSAIMAGVSYAVTYALDVHIGKTFSAGIIDFVSFGVLPAMDGFKTNWINVILWGLTMA
AIYYTVFRFAIRKFNLKTVGREDTQSKAITLDNEDLASEITILIGGAANITSIGACITRLRLQIKDQALVNEQGIKDLGA
MGVIKVGSNGLQIILGSRAQFVADLMSERTGESPSALSTNPS
>Mature_522_residues
MIKFVGILTILKDFIMLDSFKSGLSKLSLIGKALMLPISILPAAGLLLAFGAKLDIPLMMRAGGVIFDNLALLFAVGAAV
GLTKESGIAALAAIVAMVVMNATMGVALGITPEMAMGGGRYAMVMGIPSLQTGVFGGLIAGILAAVMYQRFYDTKLPDFL
GFFAGKRFVPIVTAFSAFLIGLVLPHIWSYIQSGIDALSHMANGGNMYVSTFIYGFMERALIPVGLHHIFYSPYWFSFGE
YTTAAGTIVNGDHTIWFKMLEDGVKTFSTSEYQEAGKFLSGNFAIYMFAFPAACLAMYHEANDKNKKIAAGILGSAALTS
FVTGITEPVEFAFIFVAPLLYVFSAIMAGVSYAVTYALDVHIGKTFSAGIIDFVSFGVLPAMDGFKTNWINVILWGLTMA
AIYYTVFRFAIRKFNLKTVGREDTQSKAITLDNEDLASEITILIGGAANITSIGACITRLRLQIKDQALVNEQGIKDLGA
MGVIKVGSNGLQIILGSRAQFVADLMSERTGESPSALSTNPS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787343, Length=505, Percent_Identity=41.7821782178218, Blast_Score=360, Evalue=1e-100,
Organism=Escherichia coli, GI1786894, Length=501, Percent_Identity=39.7205588822355, Blast_Score=309, Evalue=3e-85,
Organism=Escherichia coli, GI1787908, Length=513, Percent_Identity=36.4522417153996, Blast_Score=288, Evalue=9e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011055
- InterPro:   IPR018113
- InterPro:   IPR001127
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011299 [H]

Pfam domain/function: PF00358 PTS_EIIA_1; PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 55901; Mature: 55901

Theoretical pI: Translated: 7.67; Mature: 7.67

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure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CEEEEECCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA