Click here to switch to the map view.

The map label for this gene is epd [H]

Identifier: 218710595

GI number: 218710595

Start: 2833579

End: 2834640

Strand: Reverse

Name: epd [H]

Synonym: VS_2648

Alternate gene names: 218710595

Gene position: 2834640-2833579 (Counterclockwise)

Preceding gene: 218710596

Following gene: 294514842

Centisome position: 85.92

GC content: 43.97

Gene sequence:

>1062_bases
ATGTACGGAACTATGCTAAAAGTCGCGATAAACGGATTTGGACGAATAGGGCGCAATGTATTGCGCGCTGTCTATGAAAG
TGGCAAAAGCCAACAAATCAAAGTAGTAGCGGTCAATGAGCTTGCTCAACCTGACGCTATGGCTCACCTATTGCAGTACG
ACACCAGTCACGGCCGCTTCGGCAAGAAAATCTCTAATGATCAAGAGCACATTTATGTTCATCATGGCATTGGTGCTGAA
GATAAAGGCGAGTTTGATACTATTCGTATCTTACACCTGGCTGATATTGAACTATTGCCTTGGCGTGATCTTGAAGTCGA
TATTGTTCTCGATTGTACCGGTGTTTACGGTTGCCGAGATGATGGCCTAGCGCACATCGCTGCTGGAGCTAAAAAGGTAC
TGTTTTCACACCCTGGAGCTAACGACCTTGATAACACCATTATTTACGGTGTGAATCACGACACTATTACCGCTGACCAT
CGAATCGTTTCCAATGGTTCATGCACGACTAACTGTATTGTCCCTATCATCAAGGTGCTTGATGATGCTTTTGGTATTGA
GTCCGGCACAATTACGACCATTCACTCTTCTATGAATGACCAGCAAGTTATCGATGCATACCACAGCGACCTTCGTCGAA
CTCGAGCAGCAAGCCAATCAATCATTCCTGTCGATACCAAATTGCATAAAGGTATTGAAAGAATCTTTCCGAAATTTTCT
AACAAATTTGAAGCGATATCCGTGCGTGTGCCAACGGTAAACGTCACTGCGATGGATTTAAGTGTCACAATTAATGCAAA
TGTGAAAGTTAATGACGTAAATCAAACCATTGTTAATGCATCCCAGTGTACATTACACAATATAGTTGACTATACTGAAG
CGCCGCTCGTTTCCATCGACTTTAATCACGATCCCCATAGCGCAATCGTTGATGGTTCACAAACTCGAGTGAGCAATGGC
ACCTTAGTGAAAATGCTGGTGTGGTGTGACAATGAATGGGGCTTTGCGAACCGGATGCTGGATACGGTTCTTGCAATGCA
AGCTTCAGAAGGCAAGAAGTAA

Upstream 100 bases:

>100_bases
TATTTGTATCTAAAGTTATGTGCTTATGGCAGCTTTAGTATTCAATTAATGCGCTTTGAATAGGATTCAGTTATCATCTG
TTGCACGAAATTTTGGTTAG

Downstream 100 bases:

>100_bases
GACCTAGAAGCAAATGTGTGGATTATTTATTTTTTATCTTGAAATAAATGCTATGTGTCCACATATTATTAGCAGTTAAA
GTATTACCAGTTGAATAATT

Product: erythrose 4-phosphate dehydrogenase

Products: NA

Alternate protein names: E4PDH [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MYGTMLKVAINGFGRIGRNVLRAVYESGKSQQIKVVAVNELAQPDAMAHLLQYDTSHGRFGKKISNDQEHIYVHHGIGAE
DKGEFDTIRILHLADIELLPWRDLEVDIVLDCTGVYGCRDDGLAHIAAGAKKVLFSHPGANDLDNTIIYGVNHDTITADH
RIVSNGSCTTNCIVPIIKVLDDAFGIESGTITTIHSSMNDQQVIDAYHSDLRRTRAASQSIIPVDTKLHKGIERIFPKFS
NKFEAISVRVPTVNVTAMDLSVTINANVKVNDVNQTIVNASQCTLHNIVDYTEAPLVSIDFNHDPHSAIVDGSQTRVSNG
TLVKMLVWCDNEWGFANRMLDTVLAMQASEGKK

Sequences:

>Translated_353_residues
MYGTMLKVAINGFGRIGRNVLRAVYESGKSQQIKVVAVNELAQPDAMAHLLQYDTSHGRFGKKISNDQEHIYVHHGIGAE
DKGEFDTIRILHLADIELLPWRDLEVDIVLDCTGVYGCRDDGLAHIAAGAKKVLFSHPGANDLDNTIIYGVNHDTITADH
RIVSNGSCTTNCIVPIIKVLDDAFGIESGTITTIHSSMNDQQVIDAYHSDLRRTRAASQSIIPVDTKLHKGIERIFPKFS
NKFEAISVRVPTVNVTAMDLSVTINANVKVNDVNQTIVNASQCTLHNIVDYTEAPLVSIDFNHDPHSAIVDGSQTRVSNG
TLVKMLVWCDNEWGFANRMLDTVLAMQASEGKK
>Mature_353_residues
MYGTMLKVAINGFGRIGRNVLRAVYESGKSQQIKVVAVNELAQPDAMAHLLQYDTSHGRFGKKISNDQEHIYVHHGIGAE
DKGEFDTIRILHLADIELLPWRDLEVDIVLDCTGVYGCRDDGLAHIAAGAKKVLFSHPGANDLDNTIIYGVNHDTITADH
RIVSNGSCTTNCIVPIIKVLDDAFGIESGTITTIHSSMNDQQVIDAYHSDLRRTRAASQSIIPVDTKLHKGIERIFPKFS
NKFEAISVRVPTVNVTAMDLSVTINANVKVNDVNQTIVNASQCTLHNIVDYTEAPLVSIDFNHDPHSAIVDGSQTRVSNG
TLVKMLVWCDNEWGFANRMLDTVLAMQASEGKK

Specific function: Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate [H]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. Epd subfamily [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=351, Percent_Identity=35.3276353276353, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI7657116, Length=344, Percent_Identity=34.8837209302326, Blast_Score=205, Evalue=4e-53,
Organism=Escherichia coli, GI1789295, Length=341, Percent_Identity=68.6217008797654, Blast_Score=499, Evalue=1e-143,
Organism=Escherichia coli, GI1788079, Length=341, Percent_Identity=36.6568914956012, Blast_Score=228, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI17534677, Length=340, Percent_Identity=36.7647058823529, Blast_Score=230, Evalue=1e-60,
Organism=Caenorhabditis elegans, GI17534679, Length=340, Percent_Identity=36.4705882352941, Blast_Score=228, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI32566163, Length=343, Percent_Identity=35.8600583090379, Blast_Score=218, Evalue=5e-57,
Organism=Caenorhabditis elegans, GI17568413, Length=339, Percent_Identity=35.9882005899705, Blast_Score=217, Evalue=8e-57,
Organism=Saccharomyces cerevisiae, GI6322468, Length=341, Percent_Identity=37.8299120234604, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6322409, Length=343, Percent_Identity=37.6093294460641, Blast_Score=243, Evalue=3e-65,
Organism=Saccharomyces cerevisiae, GI6321631, Length=341, Percent_Identity=38.41642228739, Blast_Score=242, Evalue=5e-65,
Organism=Drosophila melanogaster, GI85725000, Length=348, Percent_Identity=34.7701149425287, Blast_Score=221, Evalue=5e-58,
Organism=Drosophila melanogaster, GI22023983, Length=348, Percent_Identity=34.7701149425287, Blast_Score=221, Evalue=5e-58,
Organism=Drosophila melanogaster, GI19922412, Length=345, Percent_Identity=34.4927536231884, Blast_Score=218, Evalue=4e-57,
Organism=Drosophila melanogaster, GI17933600, Length=348, Percent_Identity=33.9080459770115, Blast_Score=217, Evalue=1e-56,
Organism=Drosophila melanogaster, GI18110149, Length=348, Percent_Identity=33.9080459770115, Blast_Score=217, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006422
- InterPro:   IPR020831
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.72 [H]

Molecular weight: Translated: 38814; Mature: 38814

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYGTMLKVAINGFGRIGRNVLRAVYESGKSQQIKVVAVNELAQPDAMAHLLQYDTSHGRF
CCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCC
GKKISNDQEHIYVHHGIGAEDKGEFDTIRILHLADIELLPWRDLEVDIVLDCTGVYGCRD
CCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECEEEECCCCCEEEEEEEECCCCCCCC
DGLAHIAAGAKKVLFSHPGANDLDNTIIYGVNHDTITADHRIVSNGSCTTNCIVPIIKVL
CCCHHHHCCCCEEEEECCCCCCCCCCEEEECCCCEEECCCEEECCCCCCHHHHHHHHHHH
DDAFGIESGTITTIHSSMNDQQVIDAYHSDLRRTRAASQSIIPVDTKLHKGIERIFPKFS
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHC
NKFEAISVRVPTVNVTAMDLSVTINANVKVNDVNQTIVNASQCTLHNIVDYTEAPLVSID
CCEEEEEEEECEEEEEEEEEEEEEECCEEEECCHHHHHCCHHHHHHHHHCCCCCCEEEEE
FNHDPHSAIVDGSQTRVSNGTLVKMLVWCDNEWGFANRMLDTVLAMQASEGKK
CCCCCCCEEECCCCEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MYGTMLKVAINGFGRIGRNVLRAVYESGKSQQIKVVAVNELAQPDAMAHLLQYDTSHGRF
CCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCC
GKKISNDQEHIYVHHGIGAEDKGEFDTIRILHLADIELLPWRDLEVDIVLDCTGVYGCRD
CCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEECEEEECCCCCEEEEEEEECCCCCCCC
DGLAHIAAGAKKVLFSHPGANDLDNTIIYGVNHDTITADHRIVSNGSCTTNCIVPIIKVL
CCCHHHHCCCCEEEEECCCCCCCCCCEEEECCCCEEECCCEEECCCCCCHHHHHHHHHHH
DDAFGIESGTITTIHSSMNDQQVIDAYHSDLRRTRAASQSIIPVDTKLHKGIERIFPKFS
HHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHC
NKFEAISVRVPTVNVTAMDLSVTINANVKVNDVNQTIVNASQCTLHNIVDYTEAPLVSID
CCEEEEEEEECEEEEEEEEEEEEEECCEEEECCHHHHHCCHHHHHHHHHCCCCCCEEEEE
FNHDPHSAIVDGSQTRVSNGTLVKMLVWCDNEWGFANRMLDTVLAMQASEGKK
CCCCCCCEEECCCCEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA