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The map label for this gene is fldA [H]

Identifier: 218710223

GI number: 218710223

Start: 2423594

End: 2424127

Strand: Direct

Name: fldA [H]

Synonym: VS_2256

Alternate gene names: 218710223

Gene position: 2423594-2424127 (Clockwise)

Preceding gene: 218710222

Following gene: 218710225

Centisome position: 73.46

GC content: 44.57

Gene sequence:

>534_bases
ATGGCAAGTGTAGGTCTCTTCTTTGGTAGCGATACAGGTAACACTGAAGCTGTTGCTAAGATGATTCAAAAGCAATTGGG
CAAGCAGCTCGTTCAAGTTCAAGACATTGCAAAAAGCAGCAAAGAAGATATCGATAACTTCGATCTGCTGCTGCTTGGTA
TCCCTACGTGGTACTACGGCGAAGCACAATGTGATTGGGATGACTTTTTCCCTGAGCTAGAAGCTATTGATTTCTCAACT
AAGCTTGTTGCTATTTTTGGTTGTGGCGACCAAGAAGATTACGCAGAATACTTCTGCGATGCTATGGGTACTATCCGCGA
TATCGTTGAAGCAAAAGGCGGTACTATCCTAGGTCACACGTCAACTGAAGGCTACGAATTCGAAGCATCGAAAGGTTTAG
TTGAAGGCGATGACAGCCAGTTCGTTGGTCTATGTATCGATGAAGACCGTCAACCTGAGCTGACTGATGAGCGTGTATCT
AACTGGGTTAAACAAATCCACGAAGAGATGTGCCTAGCAGAGCTTGAAGACTAA

Upstream 100 bases:

>100_bases
AAAAGGGATAATCCAACTAAGCTGGGAAGGAACTGGAATCTAACGATTTCCTCCGAACTTTATTACACCGACAACAGACA
AAATGAAAGGTAATGATTCT

Downstream 100 bases:

>100_bases
TTCATTAGCGGTCATTAATTGTTACAATTAATGACCGTTATGTAGATATGAAAAAACCTCCTTATAGGAGGTTTTTTTCT
ATTCAATATTTATCAATCAA

Product: flavodoxin FldA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 176

Protein sequence:

>177_residues
MASVGLFFGSDTGNTEAVAKMIQKQLGKQLVQVQDIAKSSKEDIDNFDLLLLGIPTWYYGEAQCDWDDFFPELEAIDFST
KLVAIFGCGDQEDYAEYFCDAMGTIRDIVEAKGGTILGHTSTEGYEFEASKGLVEGDDSQFVGLCIDEDRQPELTDERVS
NWVKQIHEEMCLAELED

Sequences:

>Translated_177_residues
MASVGLFFGSDTGNTEAVAKMIQKQLGKQLVQVQDIAKSSKEDIDNFDLLLLGIPTWYYGEAQCDWDDFFPELEAIDFST
KLVAIFGCGDQEDYAEYFCDAMGTIRDIVEAKGGTILGHTSTEGYEFEASKGLVEGDDSQFVGLCIDEDRQPELTDERVS
NWVKQIHEEMCLAELED
>Mature_176_residues
ASVGLFFGSDTGNTEAVAKMIQKQLGKQLVQVQDIAKSSKEDIDNFDLLLLGIPTWYYGEAQCDWDDFFPELEAIDFSTK
LVAIFGCGDQEDYAEYFCDAMGTIRDIVEAKGGTILGHTSTEGYEFEASKGLVEGDDSQFVGLCIDEDRQPELTDERVSN
WVKQIHEEMCLAELED

Specific function: Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase [H]

COG id: COG0716

COG function: function code C; Flavodoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1786900, Length=175, Percent_Identity=74.8571428571429, Blast_Score=273, Evalue=7e-75,
Organism=Escherichia coli, GI1789262, Length=169, Percent_Identity=40.8284023668639, Blast_Score=142, Evalue=1e-35,

Paralogues:

None

Copy number: 242 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR001226
- InterPro:   IPR010086 [H]

Pfam domain/function: PF00258 Flavodoxin_1 [H]

EC number: NA

Molecular weight: Translated: 19749; Mature: 19618

Theoretical pI: Translated: 3.78; Mature: 3.78

Prosite motif: PS00201 FLAVODOXIN ; PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASVGLFFGSDTGNTEAVAKMIQKQLGKQLVQVQDIAKSSKEDIDNFDLLLLGIPTWYYG
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECC
EAQCDWDDFFPELEAIDFSTKLVAIFGCGDQEDYAEYFCDAMGTIRDIVEAKGGTILGHT
CCCCCHHHHCCCHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
STEGYEFEASKGLVEGDDSQFVGLCIDEDRQPELTDERVSNWVKQIHEEMCLAELED
CCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ASVGLFFGSDTGNTEAVAKMIQKQLGKQLVQVQDIAKSSKEDIDNFDLLLLGIPTWYYG
CCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCEECC
EAQCDWDDFFPELEAIDFSTKLVAIFGCGDQEDYAEYFCDAMGTIRDIVEAKGGTILGHT
CCCCCHHHHCCCHHHCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
STEGYEFEASKGLVEGDDSQFVGLCIDEDRQPELTDERVSNWVKQIHEEMCLAELED
CCCCEEEECCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]