Click here to switch to the map view.

The map label for this gene is yfbQ [H]

Identifier: 218710163

GI number: 218710163

Start: 2343382

End: 2344614

Strand: Direct

Name: yfbQ [H]

Synonym: VS_2193

Alternate gene names: 218710163

Gene position: 2343382-2344614 (Clockwise)

Preceding gene: 218710156

Following gene: 218710164

Centisome position: 71.03

GC content: 47.36

Gene sequence:

>1233_bases
ATGCAAAATATCGGGATGTCGTCAAAACTCAACAGCGTATGCTACGAAATCAGGGGGCCTGTACTCAAACATGCTAAGCG
CATGGAAGAAGAAGGGCATAAAATACTGAAGCTTAATATTGGTAACCCCGCCCCATTTGGTTTTGACGCCCCTGATGAAA
TCCTTGTTGATGTAATCCGTAACCTACCGACATCTCAAGGTTACTGCGACTCAAAAGGCATCTATTCAGCCCGCAAAGCG
GTTGTTCAGCACTACCAGAAAAAAGGCCTACGTAACCTTGATGTAGAAGACGTTTACATTGGTAACGGCGCATCAGAGCT
TATCGTTATGTCTATGCAGGCGCTACTGGATAATGGTGATGAAATCTTAGTTCCCGCTCCAGACTACCCACTATGGACAG
CGTCTGTTGCGCTTTCTGGTGGTACACCTGTTCATTACATGTGTGATGAAGATGCCGATTGGTACCCAGACCTTGATGAC
ATGCGTGCGAAGATCTCACCAAAGACTCGCGGCATCGTTCTTATCAACCCGAACAACCCAACAGGCGCTGTATACAGCCG
TGATTTCCTATTACAAGTTGTTGAAATTGCTCGTGAGCACGGGTTAATTATCTTCGCTGATGAAATCTACGACAAAGTGC
TTTACGACGGTGCGGTACACACTTCAGTTGCAACGCTTGCCGAAGATGTATTAATGGTCACATTCAACGGTCTGTCTAAG
GCTTACCGTGTATGTGGTTTCCGTGGTGGCTGGATGTTCTTAACGGGTCCAAAACACATAGCGAAAGGCTACGTTGAAGG
GCTAGAAATGCTGGCCTCGATGCGTTTGTGTGCCAACGTGCCAATGCAACACGCTATCCAAACTGCACTCGGTGGTTATC
AGAGTATCAATGAGCTGATTCTTCCTGGTGGTCGACTGCTTGAACAGCGCGACCGTGCATGGGAACTGATCAACAAGATC
CCTGGCGTTTCTTGTGTGAAACCGAAAGGCGCAATGTACCTGTTCCCTAAAATCGACACCAAGATGTACAACATCAAAGA
CGATCAGAAGTTTGTACTCGACTTCCTTAAGCAAGAGAAGGTGTTATTGGTTCAAGGTACTGGCTTCAACTGGCCGAAAC
CGGATCACTTCCGCATCGTGACTCTGCCGCACATCGAAGATCTAGAAATCGCGATTGGTCGTCTAGAGCGCTTCTTACAG
ACCTACAGTCAAGACGACCTCATCGAAGGTTAA

Upstream 100 bases:

>100_bases
ACGTGACACTGAAATACGACATTCATCAGATTTTTATTCTATCAAACGTCATTTTGCGGTACTTTAATAAAGTATTTAAA
TTAATTTCAGGAAATCGGCA

Downstream 100 bases:

>100_bases
TGAGCACAAAGAAAGATGGCTACAATTTGCTGTTTTAAAAGACTTTAACTTGTATTCATTCACTTCTATGCTTAAAAGGC
TCCTGTTTAGGAGCCTTTTT

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MQNIGMSSKLNSVCYEIRGPVLKHAKRMEEEGHKILKLNIGNPAPFGFDAPDEILVDVIRNLPTSQGYCDSKGIYSARKA
VVQHYQKKGLRNLDVEDVYIGNGASELIVMSMQALLDNGDEILVPAPDYPLWTASVALSGGTPVHYMCDEDADWYPDLDD
MRAKISPKTRGIVLINPNNPTGAVYSRDFLLQVVEIAREHGLIIFADEIYDKVLYDGAVHTSVATLAEDVLMVTFNGLSK
AYRVCGFRGGWMFLTGPKHIAKGYVEGLEMLASMRLCANVPMQHAIQTALGGYQSINELILPGGRLLEQRDRAWELINKI
PGVSCVKPKGAMYLFPKIDTKMYNIKDDQKFVLDFLKQEKVLLVQGTGFNWPKPDHFRIVTLPHIEDLEIAIGRLERFLQ
TYSQDDLIEG

Sequences:

>Translated_410_residues
MQNIGMSSKLNSVCYEIRGPVLKHAKRMEEEGHKILKLNIGNPAPFGFDAPDEILVDVIRNLPTSQGYCDSKGIYSARKA
VVQHYQKKGLRNLDVEDVYIGNGASELIVMSMQALLDNGDEILVPAPDYPLWTASVALSGGTPVHYMCDEDADWYPDLDD
MRAKISPKTRGIVLINPNNPTGAVYSRDFLLQVVEIAREHGLIIFADEIYDKVLYDGAVHTSVATLAEDVLMVTFNGLSK
AYRVCGFRGGWMFLTGPKHIAKGYVEGLEMLASMRLCANVPMQHAIQTALGGYQSINELILPGGRLLEQRDRAWELINKI
PGVSCVKPKGAMYLFPKIDTKMYNIKDDQKFVLDFLKQEKVLLVQGTGFNWPKPDHFRIVTLPHIEDLEIAIGRLERFLQ
TYSQDDLIEG
>Mature_410_residues
MQNIGMSSKLNSVCYEIRGPVLKHAKRMEEEGHKILKLNIGNPAPFGFDAPDEILVDVIRNLPTSQGYCDSKGIYSARKA
VVQHYQKKGLRNLDVEDVYIGNGASELIVMSMQALLDNGDEILVPAPDYPLWTASVALSGGTPVHYMCDEDADWYPDLDD
MRAKISPKTRGIVLINPNNPTGAVYSRDFLLQVVEIAREHGLIIFADEIYDKVLYDGAVHTSVATLAEDVLMVTFNGLSK
AYRVCGFRGGWMFLTGPKHIAKGYVEGLEMLASMRLCANVPMQHAIQTALGGYQSINELILPGGRLLEQRDRAWELINKI
PGVSCVKPKGAMYLFPKIDTKMYNIKDDQKFVLDFLKQEKVLLVQGTGFNWPKPDHFRIVTLPHIEDLEIAIGRLERFLQ
TYSQDDLIEG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=474, Percent_Identity=25.9493670886076, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=27.9891304347826, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI4885351, Length=450, Percent_Identity=25.5555555555556, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI4507369, Length=378, Percent_Identity=28.3068783068783, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI56713254, Length=319, Percent_Identity=25.3918495297806, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI56713256, Length=319, Percent_Identity=25.3918495297806, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI95147551, Length=181, Percent_Identity=29.2817679558011, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI169881279, Length=181, Percent_Identity=29.2817679558011, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI149944424, Length=361, Percent_Identity=24.9307479224377, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI169881281, Length=167, Percent_Identity=28.1437125748503, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=75.4950495049505, Blast_Score=666, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=380, Percent_Identity=28.9473684210526, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1786816, Length=234, Percent_Identity=25.6410256410256, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=28.9189189189189, Blast_Score=159, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI71981209, Length=463, Percent_Identity=25.7019438444924, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI71981215, Length=293, Percent_Identity=26.6211604095563, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=209, Percent_Identity=30.1435406698565, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=207, Percent_Identity=29.4685990338164, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=175, Percent_Identity=29.1428571428571, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323118, Length=360, Percent_Identity=28.0555555555556, Blast_Score=139, Evalue=6e-34,
Organism=Saccharomyces cerevisiae, GI6320317, Length=363, Percent_Identity=27.5482093663912, Blast_Score=129, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6322401, Length=277, Percent_Identity=23.4657039711191, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI18859735, Length=383, Percent_Identity=27.4151436031332, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24641770, Length=457, Percent_Identity=25.601750547046, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24641760, Length=457, Percent_Identity=25.601750547046, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24641768, Length=457, Percent_Identity=25.601750547046, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24641766, Length=457, Percent_Identity=25.601750547046, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24641764, Length=457, Percent_Identity=25.601750547046, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI45551451, Length=457, Percent_Identity=25.601750547046, Blast_Score=128, Evalue=7e-30,
Organism=Drosophila melanogaster, GI28573069, Length=207, Percent_Identity=26.0869565217391, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24646114, Length=207, Percent_Identity=26.0869565217391, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28573067, Length=207, Percent_Identity=26.0869565217391, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI28573065, Length=207, Percent_Identity=26.0869565217391, Blast_Score=87, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45862; Mature: 45862

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNIGMSSKLNSVCYEIRGPVLKHAKRMEEEGHKILKLNIGNPAPFGFDAPDEILVDVIR
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTSQGYCDSKGIYSARKAVVQHYQKKGLRNLDVEDVYIGNGASELIVMSMQALLDNGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
EILVPAPDYPLWTASVALSGGTPVHYMCDEDADWYPDLDDMRAKISPKTRGIVLINPNNP
EEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGAVYSRDFLLQVVEIAREHGLIIFADEIYDKVLYDGAVHTSVATLAEDVLMVTFNGLSK
CCCHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHEEEEHHHHH
AYRVCGFRGGWMFLTGPKHIAKGYVEGLEMLASMRLCANVPMQHAIQTALGGYQSINELI
HHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRDRAWELINKIPGVSCVKPKGAMYLFPKIDTKMYNIKDDQKFVLDFLKQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCEEECCCCHHHHHHHHHCCCC
VLLVQGTGFNWPKPDHFRIVTLPHIEDLEIAIGRLERFLQTYSQDDLIEG
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQNIGMSSKLNSVCYEIRGPVLKHAKRMEEEGHKILKLNIGNPAPFGFDAPDEILVDVIR
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLPTSQGYCDSKGIYSARKAVVQHYQKKGLRNLDVEDVYIGNGASELIVMSMQALLDNGD
CCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCC
EILVPAPDYPLWTASVALSGGTPVHYMCDEDADWYPDLDDMRAKISPKTRGIVLINPNNP
EEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHCCCCCCEEEEECCCCC
TGAVYSRDFLLQVVEIAREHGLIIFADEIYDKVLYDGAVHTSVATLAEDVLMVTFNGLSK
CCCHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHCCHHHHHHHHHHHHHHEEEEHHHHH
AYRVCGFRGGWMFLTGPKHIAKGYVEGLEMLASMRLCANVPMQHAIQTALGGYQSINELI
HHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHH
LPGGRLLEQRDRAWELINKIPGVSCVKPKGAMYLFPKIDTKMYNIKDDQKFVLDFLKQEK
CCCHHHHHHHHHHHHHHHHCCCCEEECCCCCEEEEECCCCEEECCCCHHHHHHHHHCCCC
VLLVQGTGFNWPKPDHFRIVTLPHIEDLEIAIGRLERFLQTYSQDDLIEG
EEEEEECCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]