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The map label for this gene is focA [H]

Identifier: 218709989

GI number: 218709989

Start: 2155035

End: 2155877

Strand: Reverse

Name: focA [H]

Synonym: VS_2008

Alternate gene names: 218709989

Gene position: 2155877-2155035 (Counterclockwise)

Preceding gene: 218709990

Following gene: 218709988

Centisome position: 65.34

GC content: 44.6

Gene sequence:

>843_bases
ATGAATCTAAACCAATTCGACTCATTATTACCGCCACAAATGGCTGAGCGCGCTGCAGATATTGGCGTAGGTAAAGCAAC
CAAAGATCCAATCAAATCTTTTCTCCTAGCGATCTCTGCCGGCATACATATTGGTATCGCGTTTGTGTTCTACACTATCG
TGACTACCGGTGCTGGTGATTTACCGTGGGGTATTACTCGCTTATTGGGTGGTCTAGCTTTTAGCTTAGGATTAATCCTT
GTTGTTGTTACTGGTGGTGAACTGTTTACCAGCTCGGTGTTGACGCTTGTTGCTCGCGCAAGTGGCAAGATTACCTGGCG
TACATTAGTTAAGAACTGGACCACGGTTTATGTAGGTAACTTAATTGGTGCATTGCTGCTGGTGGCCTGTATGCTTCTGA
CTAAACAGTACATGTTCGATCATGGACAAGTGGGTTTGAATGCCATGGCTATTTCCCAACACAAAATGCACCATGATTTT
ATCCAAGCTATCGCGCTTGGCATCATGTGTAATGTGTTGGTTTGTATCGCGGTATGGATGACGTTTAGTGGACGTACACT
GACTGACAAAATCGCAGTTATGATTTTACCTGTGGCGATGTTCGTATCAGCCGGTTTTGAGCACTGTATTGCCAACATGT
TCCAAGTCCCTTTAGCTATCGGTATCAAAACATTTGCTCCCGCAGAATTTTGGACAATGACAGGCGCTAACCCTGCGGAC
TATGTTGATCTGAACATGATGGACTTTTTGATGAACAACTTGCTGCCCGTTACCATTGGTAACATCATTGGCGGTGGTAT
CTTTGTTGGTATGTGGTACTGGTTGATCTACCTACGTGACTAA

Upstream 100 bases:

>100_bases
GGTTGTGAGAGGCATTTCGAGCTTAAAATAGCTCTTGAATTCAGAAATGAAAGAGAGGATTATCGCGCTCCCGACGACAT
GTTTCAAAATGTAAATCATC

Downstream 100 bases:

>100_bases
TAAGGGTGGCGTGATCCACCAAGCAAAGGTTTCGTGATTAATTCCGATTACGCGGTTAATTCAGTTTACGAGTTAACTGG
GTAACTTGGACTCAGTGAAA

Product: formate transporter 1

Products: formate [Periplasm]; formate [Cytoplasm] [C]

Alternate protein names: Formate channel 1 [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MNLNQFDSLLPPQMAERAADIGVGKATKDPIKSFLLAISAGIHIGIAFVFYTIVTTGAGDLPWGITRLLGGLAFSLGLIL
VVVTGGELFTSSVLTLVARASGKITWRTLVKNWTTVYVGNLIGALLLVACMLLTKQYMFDHGQVGLNAMAISQHKMHHDF
IQAIALGIMCNVLVCIAVWMTFSGRTLTDKIAVMILPVAMFVSAGFEHCIANMFQVPLAIGIKTFAPAEFWTMTGANPAD
YVDLNMMDFLMNNLLPVTIGNIIGGGIFVGMWYWLIYLRD

Sequences:

>Translated_280_residues
MNLNQFDSLLPPQMAERAADIGVGKATKDPIKSFLLAISAGIHIGIAFVFYTIVTTGAGDLPWGITRLLGGLAFSLGLIL
VVVTGGELFTSSVLTLVARASGKITWRTLVKNWTTVYVGNLIGALLLVACMLLTKQYMFDHGQVGLNAMAISQHKMHHDF
IQAIALGIMCNVLVCIAVWMTFSGRTLTDKIAVMILPVAMFVSAGFEHCIANMFQVPLAIGIKTFAPAEFWTMTGANPAD
YVDLNMMDFLMNNLLPVTIGNIIGGGIFVGMWYWLIYLRD
>Mature_280_residues
MNLNQFDSLLPPQMAERAADIGVGKATKDPIKSFLLAISAGIHIGIAFVFYTIVTTGAGDLPWGITRLLGGLAFSLGLIL
VVVTGGELFTSSVLTLVARASGKITWRTLVKNWTTVYVGNLIGALLLVACMLLTKQYMFDHGQVGLNAMAISQHKMHHDF
IQAIALGIMCNVLVCIAVWMTFSGRTLTDKIAVMILPVAMFVSAGFEHCIANMFQVPLAIGIKTFAPAEFWTMTGANPAD
YVDLNMMDFLMNNLLPVTIGNIIGGGIFVGMWYWLIYLRD

Specific function: Involved in the bidirectional transport of formate [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI1787132, Length=277, Percent_Identity=58.1227436823105, Blast_Score=339, Evalue=1e-94,
Organism=Escherichia coli, GI1788837, Length=279, Percent_Identity=42.6523297491039, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI87082249, Length=271, Percent_Identity=27.6752767527675, Blast_Score=68, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6321779, Length=225, Percent_Identity=26.6666666666667, Blast_Score=77, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 30426; Mature: 30426

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS01005 FORMATE_NITRITE_TP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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EEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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EEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate [Cytoplasm]; formate [Periplasm] [C]

Specific reaction: formate [Cytoplasm] = formate [Periplasm] formate [Periplasm] = formate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]