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The map label for this gene is sapC [H]

Identifier: 218709976

GI number: 218709976

Start: 2142742

End: 2143629

Strand: Direct

Name: sapC [H]

Synonym: VS_1995

Alternate gene names: 218709976

Gene position: 2142742-2143629 (Clockwise)

Preceding gene: 218709975

Following gene: 218709977

Centisome position: 64.95

GC content: 46.17

Gene sequence:

>888_bases
ATGCTAACAAATAACGTCTACCAAGAAGAACAGATTCCAACTCAATTCGAGCGTTTCTGGCGCAGCTTCCGTGGCAATAA
TCTCGCAATGTTTGGACTATGGTGTTTGGTCTTGATCATTCTGATCACCATCACTTCACCATGGCTAGCACCGCATGATG
CTCAAGAGCAGACGGGGCACCTACTAACACCTCCTTCTTGGGATCCTGCTGGAACAGTTGAGTATTTTCTAGGTACTGAT
GATTTAGGGCGAGATATTCTATCCCGTCTGATTATTGGCTCTCAGCTGACATTTGGTGCCGCAGTGGTGATTACCTTTAT
CGCAGCAGTCATTGGTTGCCTGATTGGCGTACTTGCAGGTATGACTCGTGGGTTGCTATCAAGCACGCTAAACCACCTGC
TTGACACGGTAATGTCTATTCCGTCGCTGCTACTCGCGATTATCTTCGTGGCATTTCTTGGCTTTGGCGAGTTTAATATC
TTGCTAGCCTTATGTTTGGCATTGATTCCACGCTTTATTCGTTCGGTATACATTGCCGTGCATGCAGAAGTAGAAAAAGA
CTATATTTTGGCTTCTCGCCTTGATGGTGCGAATGACTTCTACCTGTTATGGAATTCAATCCTTCCTAATATTCTTACTG
TGGTGGCACTTGAAATTACACTGGCATTGTCAGTCGCCATTCTTGATATCACGGCCTTGGGTTTCTTAGGGCTTGGCGCT
CAAGCACCCAGTACCGAATGGGGCTCAATTTTGGGTGACTCTGTAGAGCTGATTTACCTTGCGCCATGGACAGTAACTCT
ACCCGGCTTAGCCATTATGTTTACAGTGATCGTGATTAACCTTGTCGGTGAAGGTGTTCGCCAAGCGCTAAATGCAGGAA
TCGAATAA

Upstream 100 bases:

>100_bases
CAAGCTGGTGTAATTGTGGTAGCAACCTTGGTTTTGACCGCGAATATACTGTCCGATCTACTGGGCGCGATGGTCAATCC
TCTGGTAAGGAAGGAATGGT

Downstream 100 bases:

>100_bases
TGCCGTTACTTGATATTCGACATCTCACCATCAAGATTGAGACCCCTCAAGGGATGGTTAAAGCAGTAGATCGAATGAGT
ATTACCCTCAATGAGGGAGA

Product: peptide transport system permease SapC

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MLTNNVYQEEQIPTQFERFWRSFRGNNLAMFGLWCLVLIILITITSPWLAPHDAQEQTGHLLTPPSWDPAGTVEYFLGTD
DLGRDILSRLIIGSQLTFGAAVVITFIAAVIGCLIGVLAGMTRGLLSSTLNHLLDTVMSIPSLLLAIIFVAFLGFGEFNI
LLALCLALIPRFIRSVYIAVHAEVEKDYILASRLDGANDFYLLWNSILPNILTVVALEITLALSVAILDITALGFLGLGA
QAPSTEWGSILGDSVELIYLAPWTVTLPGLAIMFTVIVINLVGEGVRQALNAGIE

Sequences:

>Translated_295_residues
MLTNNVYQEEQIPTQFERFWRSFRGNNLAMFGLWCLVLIILITITSPWLAPHDAQEQTGHLLTPPSWDPAGTVEYFLGTD
DLGRDILSRLIIGSQLTFGAAVVITFIAAVIGCLIGVLAGMTRGLLSSTLNHLLDTVMSIPSLLLAIIFVAFLGFGEFNI
LLALCLALIPRFIRSVYIAVHAEVEKDYILASRLDGANDFYLLWNSILPNILTVVALEITLALSVAILDITALGFLGLGA
QAPSTEWGSILGDSVELIYLAPWTVTLPGLAIMFTVIVINLVGEGVRQALNAGIE
>Mature_295_residues
MLTNNVYQEEQIPTQFERFWRSFRGNNLAMFGLWCLVLIILITITSPWLAPHDAQEQTGHLLTPPSWDPAGTVEYFLGTD
DLGRDILSRLIIGSQLTFGAAVVITFIAAVIGCLIGVLAGMTRGLLSSTLNHLLDTVMSIPSLLLAIIFVAFLGFGEFNI
LLALCLALIPRFIRSVYIAVHAEVEKDYILASRLDGANDFYLLWNSILPNILTVVALEITLALSVAILDITALGFLGLGA
QAPSTEWGSILGDSVELIYLAPWTVTLPGLAIMFTVIVINLVGEGVRQALNAGIE

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4171

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787549, Length=296, Percent_Identity=51.6891891891892, Blast_Score=302, Evalue=2e-83,
Organism=Escherichia coli, GI1789964, Length=296, Percent_Identity=38.8513513513513, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1787054, Length=290, Percent_Identity=35.1724137931034, Blast_Score=186, Evalue=2e-48,
Organism=Escherichia coli, GI1787760, Length=291, Percent_Identity=33.6769759450172, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1789889, Length=256, Percent_Identity=31.640625, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787498, Length=292, Percent_Identity=28.4246575342466, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1788505, Length=233, Percent_Identity=25.3218884120172, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 32054; Mature: 32054

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTNNVYQEEQIPTQFERFWRSFRGNNLAMFGLWCLVLIILITITSPWLAPHDAQEQTGH
CCCCCCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCC
LLTPPSWDPAGTVEYFLGTDDLGRDILSRLIIGSQLTFGAAVVITFIAAVIGCLIGVLAG
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MTRGLLSSTLNHLLDTVMSIPSLLLAIIFVAFLGFGEFNILLALCLALIPRFIRSVYIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
HAEVEKDYILASRLDGANDFYLLWNSILPNILTVVALEITLALSVAILDITALGFLGLGA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QAPSTEWGSILGDSVELIYLAPWTVTLPGLAIMFTVIVINLVGEGVRQALNAGIE
CCCCCCHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLTNNVYQEEQIPTQFERFWRSFRGNNLAMFGLWCLVLIILITITSPWLAPHDAQEQTGH
CCCCCCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCC
LLTPPSWDPAGTVEYFLGTDDLGRDILSRLIIGSQLTFGAAVVITFIAAVIGCLIGVLAG
CCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
MTRGLLSSTLNHLLDTVMSIPSLLLAIIFVAFLGFGEFNILLALCLALIPRFIRSVYIAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
HAEVEKDYILASRLDGANDFYLLWNSILPNILTVVALEITLALSVAILDITALGFLGLGA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
QAPSTEWGSILGDSVELIYLAPWTVTLPGLAIMFTVIVINLVGEGVRQALNAGIE
CCCCCCHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]