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The map label for this gene is nrfX [H]

Identifier: 218709914

GI number: 218709914

Start: 2070602

End: 2071183

Strand: Reverse

Name: nrfX [H]

Synonym: VS_1927

Alternate gene names: 218709914

Gene position: 2071183-2070602 (Counterclockwise)

Preceding gene: 218709915

Following gene: 218709913

Centisome position: 62.78

GC content: 42.27

Gene sequence:

>582_bases
ATGCATACCAGCGTTCGTAATAAACTCATTGCTCTATTTTCAGTGGCTGTTGCTTTGGTCGTTGCATTTTCATATGCGCT
CGACAATAAGCAACAAACGACCAGCGTTTCAGATCAAAAAAGGGCTTTCCCTGAATTTACGGCAGAAAAACTCGTTACTG
ATGAGTCATTCGATTCTGAAGCATTAAGCTCTGAAATATTAAGCTCTGAAACGGCTAAGCTTACTGATATTACTCAACAT
CCTTACCAACTGGTCAATGTATGGGCTTCATGGTGCGGAATATGTAAAACCGAGCACGCTTTTTTACTCGAACTGCAGAA
GAAAGGCATTCCAATTGTCGGTCTCAATTATCGAGATAACCCCGGTGCTGCGCTTAATGTATTGTCCAACGACGGCAATC
CGTACGCAACTGTGATCAGTGATCCTCAAGGGAAGTTGGCTTTAGAACTCGGTGTCATAGGGACTCCTGAGACGTATTTA
GTTGATGCTGAAGGCCAAATAGTTAAGAAGTTGCTAGGTGTGATTAATGAATCGGTTTGGCGCAAAGAACTCGCTCACTA
TTTTAAAGGTAAAAATGGATGA

Upstream 100 bases:

>100_bases
GCGTATGCTCGTTGGATATGGCTTGGTGGGCTGTTCTCAATTCTAGGTGCTGTGCTTTCACTGACCAATCGTAAAAAGAA
AACCGTTAAGGCTGCACAGT

Downstream 100 bases:

>100_bases
TGAAGTTCCTGCTCAACATAGTGCTCATACTTAGCTCCGCTATTGTCGTCAACTTCCCTGTAATAGCCGAGGACTTGTTT
ACGGCGAGTGATAAAGATAC

Product: thiol:disulfide interchange protein DsbE

Products: NA

Alternate protein names: Cytochrome c biogenesis protein NrfX [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MHTSVRNKLIALFSVAVALVVAFSYALDNKQQTTSVSDQKRAFPEFTAEKLVTDESFDSEALSSEILSSETAKLTDITQH
PYQLVNVWASWCGICKTEHAFLLELQKKGIPIVGLNYRDNPGAALNVLSNDGNPYATVISDPQGKLALELGVIGTPETYL
VDAEGQIVKKLLGVINESVWRKELAHYFKGKNG

Sequences:

>Translated_193_residues
MHTSVRNKLIALFSVAVALVVAFSYALDNKQQTTSVSDQKRAFPEFTAEKLVTDESFDSEALSSEILSSETAKLTDITQH
PYQLVNVWASWCGICKTEHAFLLELQKKGIPIVGLNYRDNPGAALNVLSNDGNPYATVISDPQGKLALELGVIGTPETYL
VDAEGQIVKKLLGVINESVWRKELAHYFKGKNG
>Mature_193_residues
MHTSVRNKLIALFSVAVALVVAFSYALDNKQQTTSVSDQKRAFPEFTAEKLVTDESFDSEALSSEILSSETAKLTDITQH
PYQLVNVWASWCGICKTEHAFLLELQKKGIPIVGLNYRDNPGAALNVLSNDGNPYATVISDPQGKLALELGVIGTPETYL
VDAEGQIVKKLLGVINESVWRKELAHYFKGKNG

Specific function: Could be involved in disulfide bond formation. Could catalyzes a late, reductive step in the assembly of periplasmic NrfA c-type cytochrome, probably the reduction of disulfide bonds of the apocytochrome c to allow covalent linkage with the heme. Possible

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=108, Percent_Identity=44.4444444444444, Blast_Score=104, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21170; Mature: 21170

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTSVRNKLIALFSVAVALVVAFSYALDNKQQTTSVSDQKRAFPEFTAEKLVTDESFDSE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHCCHHHHHHHHHCCCCCCHH
ALSSEILSSETAKLTDITQHPYQLVNVWASWCGICKTEHAFLLELQKKGIPIVGLNYRDN
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCC
PGAALNVLSNDGNPYATVISDPQGKLALELGVIGTPETYLVDAEGQIVKKLLGVINESVW
CCCEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHH
RKELAHYFKGKNG
HHHHHHHHCCCCC
>Mature Secondary Structure
MHTSVRNKLIALFSVAVALVVAFSYALDNKQQTTSVSDQKRAFPEFTAEKLVTDESFDSE
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHCCHHHHHHHHHCCCCCCHH
ALSSEILSSETAKLTDITQHPYQLVNVWASWCGICKTEHAFLLELQKKGIPIVGLNYRDN
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEECCCCCC
PGAALNVLSNDGNPYATVISDPQGKLALELGVIGTPETYLVDAEGQIVKKLLGVINESVW
CCCEEEEEECCCCEEEEEEECCCCCEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHHHH
RKELAHYFKGKNG
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]