Click here to switch to the map view.

The map label for this gene is asnC [H]

Identifier: 218709797

GI number: 218709797

Start: 1941379

End: 1942779

Strand: Direct

Name: asnC [H]

Synonym: VS_1809

Alternate gene names: 218709797

Gene position: 1941379-1942779 (Clockwise)

Preceding gene: 218709795

Following gene: 218709798

Centisome position: 58.84

GC content: 47.82

Gene sequence:

>1401_bases
ATGACTTACGCGCCTGTAACAGACGTACTTGGCGGCAAGCTAGCGGTAGACAGTGAAGTAACTGTTCGCGGCTGGATCCG
TTCACGTCGTGATTCCAAAGCTGGAATCTCTTTCCTTGCCATTTATGACGGCTCTTGTTTCGACCCGATTCAGGCCGTGG
TTCCTAATAATCTTAATAATTACGAAGACGAAGTATTAAAGCTAACTACTGGCTGCTCTGTTGAAGTAACAGGTAAGATT
GTTGAGTCTCCTGCGAAAGGTCAAGACTTCGAACTAGCAGCAACTGACGTTAAAGTTGTAGGTTGGGTTGAAGACGCTGA
TACTTACCCAATGGCTAAGACACGTCACTCTATCGAATACCTTCGTGAAGTTGCTCACCTACGCCCACGTACAAACGTGA
TCGGCGCAGTAGCACGTGTACGTAACTGTCTATCTCAAGCGATTCACCGTTTCTACCACGAGCAAGGTTTCTTCTGGACT
TCAGCTCCGCTTATCACTGCATCTGATGCAGAAGGCGCTGGTGAAATGTTCCGCGTATCGACGCTAGACATGGAAAACCT
ACCTCGCACTGACGAAGGCAAAGTTGACTTCAACGAAGATTTCTTCGGTAAAGAAACTTTCCTTACAGTATCTGGTCAAC
TTAATGCTGAAGCTTACGCTTGTGCACTAAGCAAGGTTTACACGTTCGGTCCTACGTTCCGTGCTGAAAACTCAAACACA
AGCCGCCACCTAGCTGAATTCTGGATGGTTGAGCCTGAAGTTGCGTTTGCAGACCTTGACGATGTAGCAAAACTGGCTGA
AGACATGCTTAAGTACGTTTTCGCTGCTGTTCTTGAAGAGCGCCGCGACGACCTTGAGTTCTTCGCTTCTCGTATCGACA
AGCAAGCAATCACTCGTCTAGAGCAATTCGTAGACGCTGATTTCGCACAAGTTGACTACACTGACGCAATCCAAATCCTA
CTAGACTCTGGTAAGAAATTTGAATTCGACGTTGAGTGGGGCATCGACATGTCTTCAGAGCATGAGCGTTACCTAGCTGA
AGAGCACTTCAAAGCACCTGTTATCGTTAAGAACTACCCGAAAGACATCAAAGCTTTCTACATGCGTTTAAACGACGACG
GCAAAACAGTTGCAGCAATGGACGTACTTGCACCAGGCATCGGTGAAATTATCGGTGGTGCACAACGTGAAGAGCGTCTA
GACATTCTAGACGAGCGTATGATTGCTATGGGTATCGACCCTGAGCACATGAGCTGGTACCGCGACCTACGTAAATACGG
CACAGTGCCTCACGCTGGCTTCGGTCTTGGCTTTGAGCGTCTAGTGTCTTACGTAACAGGTATGGGCAACGTTCGTGACG
TTATCCCGTTCCCACGTACACCACGCTCTGCTAACTTCTAA

Upstream 100 bases:

>100_bases
ACTTAATGTTTCGGCTAATTATTGTGCAAATGTATGTTTATTTGCAGCAATGCCAGAGACTTTGAGTTGAATTTGTCCCT
CAATGGAGAATGAAATCAAC

Downstream 100 bases:

>100_bases
TCTCAGCTTTCTTCTTTCAGAGAAGTCAGTATAGATAGATAATTAAATAGATAAAAACCTCCGTATATACGGAGGTTTTT
TTATTCCCCGAGATTATTTC

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 466; Mature: 465

Protein sequence:

>466_residues
MTYAPVTDVLGGKLAVDSEVTVRGWIRSRRDSKAGISFLAIYDGSCFDPIQAVVPNNLNNYEDEVLKLTTGCSVEVTGKI
VESPAKGQDFELAATDVKVVGWVEDADTYPMAKTRHSIEYLREVAHLRPRTNVIGAVARVRNCLSQAIHRFYHEQGFFWT
SAPLITASDAEGAGEMFRVSTLDMENLPRTDEGKVDFNEDFFGKETFLTVSGQLNAEAYACALSKVYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFADLDDVAKLAEDMLKYVFAAVLEERRDDLEFFASRIDKQAITRLEQFVDADFAQVDYTDAIQIL
LDSGKKFEFDVEWGIDMSSEHERYLAEEHFKAPVIVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERL
DILDERMIAMGIDPEHMSWYRDLRKYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPRSANF

Sequences:

>Translated_466_residues
MTYAPVTDVLGGKLAVDSEVTVRGWIRSRRDSKAGISFLAIYDGSCFDPIQAVVPNNLNNYEDEVLKLTTGCSVEVTGKI
VESPAKGQDFELAATDVKVVGWVEDADTYPMAKTRHSIEYLREVAHLRPRTNVIGAVARVRNCLSQAIHRFYHEQGFFWT
SAPLITASDAEGAGEMFRVSTLDMENLPRTDEGKVDFNEDFFGKETFLTVSGQLNAEAYACALSKVYTFGPTFRAENSNT
SRHLAEFWMVEPEVAFADLDDVAKLAEDMLKYVFAAVLEERRDDLEFFASRIDKQAITRLEQFVDADFAQVDYTDAIQIL
LDSGKKFEFDVEWGIDMSSEHERYLAEEHFKAPVIVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERL
DILDERMIAMGIDPEHMSWYRDLRKYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPRSANF
>Mature_465_residues
TYAPVTDVLGGKLAVDSEVTVRGWIRSRRDSKAGISFLAIYDGSCFDPIQAVVPNNLNNYEDEVLKLTTGCSVEVTGKIV
ESPAKGQDFELAATDVKVVGWVEDADTYPMAKTRHSIEYLREVAHLRPRTNVIGAVARVRNCLSQAIHRFYHEQGFFWTS
APLITASDAEGAGEMFRVSTLDMENLPRTDEGKVDFNEDFFGKETFLTVSGQLNAEAYACALSKVYTFGPTFRAENSNTS
RHLAEFWMVEPEVAFADLDDVAKLAEDMLKYVFAAVLEERRDDLEFFASRIDKQAITRLEQFVDADFAQVDYTDAIQILL
DSGKKFEFDVEWGIDMSSEHERYLAEEHFKAPVIVKNYPKDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERLD
ILDERMIAMGIDPEHMSWYRDLRKYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPRSANF

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=463, Percent_Identity=43.4125269978402, Blast_Score=391, Evalue=1e-109,
Organism=Homo sapiens, GI4758762, Length=451, Percent_Identity=29.0465631929047, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI45439306, Length=342, Percent_Identity=29.2397660818713, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1787161, Length=466, Percent_Identity=78.1115879828326, Blast_Score=791, Evalue=0.0,
Organism=Escherichia coli, GI1790571, Length=364, Percent_Identity=23.6263736263736, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1788173, Length=109, Percent_Identity=34.8623853211009, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17556372, Length=433, Percent_Identity=31.8706697459584, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71984122, Length=460, Percent_Identity=28.695652173913, Blast_Score=178, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17551876, Length=481, Percent_Identity=27.4428274428274, Blast_Score=122, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6319872, Length=469, Percent_Identity=37.3134328358209, Blast_Score=305, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6321807, Length=457, Percent_Identity=32.3851203501094, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6323011, Length=484, Percent_Identity=25.8264462809917, Blast_Score=124, Evalue=4e-29,
Organism=Drosophila melanogaster, GI19922416, Length=448, Percent_Identity=36.6071428571429, Blast_Score=278, Evalue=5e-75,
Organism=Drosophila melanogaster, GI19921528, Length=467, Percent_Identity=27.8372591006424, Blast_Score=168, Evalue=8e-42,
Organism=Drosophila melanogaster, GI17136276, Length=343, Percent_Identity=29.1545189504373, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 52418; Mature: 52286

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYAPVTDVLGGKLAVDSEVTVRGWIRSRRDSKAGISFLAIYDGSCFDPIQAVVPNNLNN
CCCCCCHHHCCCCEEECCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCC
YEDEVLKLTTGCSVEVTGKIVESPAKGQDFELAATDVKVVGWVEDADTYPMAKTRHSIEY
HHHHHEEEECCCCEEEEHHHHCCCCCCCCCEEEECCEEEEEEEECCCCCCCHHHHHHHHH
LREVAHLRPRTNVIGAVARVRNCLSQAIHRFYHEQGFFWTSAPLITASDAEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEECCCCCCCCEEEEE
TLDMENLPRTDEGKVDFNEDFFGKETFLTVSGQLNAEAYACALSKVYTFGPTFRAENSNT
ECCHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFADLDDVAKLAEDMLKYVFAAVLEERRDDLEFFASRIDKQAITRL
HHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQFVDADFAQVDYTDAIQILLDSGKKFEFDVEWGIDMSSEHERYLAEEHFKAPVIVKNYP
HHHHCCCHHHCCHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERLDILDERMIAMGIDPEHMSWY
HHHEEHEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
RDLRKYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPRSANF
HHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TYAPVTDVLGGKLAVDSEVTVRGWIRSRRDSKAGISFLAIYDGSCFDPIQAVVPNNLNN
CCCCCHHHCCCCEEECCCCHHHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHCCCCCCC
YEDEVLKLTTGCSVEVTGKIVESPAKGQDFELAATDVKVVGWVEDADTYPMAKTRHSIEY
HHHHHEEEECCCCEEEEHHHHCCCCCCCCCEEEECCEEEEEEEECCCCCCCHHHHHHHHH
LREVAHLRPRTNVIGAVARVRNCLSQAIHRFYHEQGFFWTSAPLITASDAEGAGEMFRVS
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEEEECCCCCCCCEEEEE
TLDMENLPRTDEGKVDFNEDFFGKETFLTVSGQLNAEAYACALSKVYTFGPTFRAENSNT
ECCHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEECCCCCC
SRHLAEFWMVEPEVAFADLDDVAKLAEDMLKYVFAAVLEERRDDLEFFASRIDKQAITRL
HHHHHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQFVDADFAQVDYTDAIQILLDSGKKFEFDVEWGIDMSSEHERYLAEEHFKAPVIVKNYP
HHHHCCCHHHCCHHHHHHHHHCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCC
KDIKAFYMRLNDDGKTVAAMDVLAPGIGEIIGGAQREERLDILDERMIAMGIDPEHMSWY
HHHEEHEEEECCCCCEEEHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
RDLRKYGTVPHAGFGLGFERLVSYVTGMGNVRDVIPFPRTPRSANF
HHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA